URL: http://www.wormbase.org/db/get?name=WBStrain00004531

Proper Citation: RRID:WB-STRAIN:WBStrain00004531

Description: Caenorhabditis elegans with name glp-1(e2141) from WB.

Species: Caenorhabditis elegans

Synonyms: glp-1(e2141)

Notes: Made_by: Schnabels|"Reference WBPaper00059294 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype glp-1(e2141) III."|"Supplementary_genotype [glp-1(e2141)]"|"Temperature sensitive. Sterile at 25C. Maintain at 15C. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. [2/98: Craig Mello noticed a different embryonic phenotype in this strain as compared to the e2141 stock that Jim Priess obtained from England-the ABp fate appears WT.] [NOTE (11/16/10 - J. Hubbard): This strain is NOT synonymous with glp-1(e2144) as previously reported in Kodoyianni V, Maine EM, Kimble J. (1992) [Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans. Mol Biol Cell. 3,1199-213. PMID: 1457827]. As reported in Worm Breeders Gazette December 2010; 18(3), e2144 carries the mutation c2785t in exon 8, leading to the amino acid change L929F, whereas e2141 carries the mutations c2920t and a3610g in exon 8, leading to the amino acid changes R974C and T1204A.]"|"WBStrain provided so WBPaper00060426 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00060484 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."

Affected Gene: WBGene00001609(glp-1)