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Publication

Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance.

Linda W van Laake | Li Qian | Paul Cheng | Yu Huang | Edward C Hsiao | Bruce R Conklin | Deepak Srivastava
Circulation research | 2010

Induced pluripotent stem (iPS) cells can differentiate into multiple cell types, including cardiomyocytes and have tremendous potential for drug discovery and regenerative therapies. However, it is unknown how much variability exists between differentiated lineages from independent iPS cell lines and, specifically, how similar iPS cell-derived cardiomyocytes (iPS-CMs) are to embryonic stem (ES) cell-derived cardiomyocytes (ES-CMs).

Pubmed ID: 20558827

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None found

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL089707
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL057181-13
  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL089707-01A1
  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL089707-02
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL057181-14
  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL089707-03
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL057181
  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL089707-04
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL080592
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL080592-05
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL057181-14W1
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL080592-06
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL057181-15
  • Agency: NCRR NIH HHS, United States
    Id: C06 RR018928

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B6;129P2-Tg(NKX2-5-EmGFP)2Conk/Mmnc (organism)

RRID:MMRRC_030440-UNC

Mus musculus with name B6;129P2-Tg(NKX2-5-EmGFP)2Conk/Mmnc from MMRRC.

View all literature mentions

E14 RP11-88L12 NKX2-5-EmGFP ES cell line (organism)

RRID:MMRRC_030473-UCD

Mus musculus with name E14 RP11-88L12 NKX2-5-EmGFP ES cell line from MMRRC.

View all literature mentions

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