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A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice.

David J Lloyd | Matthew C Wheeler | Nicholas Gekakis
Diabetes | 2010

Type 2 diabetes is caused by both environmental and genetic factors. To better understand the genetic factors we used forward genetics to discover genes that have not previously been implicated in the development of hyperglycemia or diabetes.

Pubmed ID: 19934005

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK079925
  • Agency: NIDDK NIH HHS, United States
    Id: DK-079925

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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