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Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique.

Jürgen E Schneider | Jens Böse | Simon D Bamforth | Achim D Gruber | Carol Broadbent | Kieran Clarke | Stefan Neubauer | Andreas Lengeling | Shoumo Bhattacharya
BMC developmental biology | 2004

Congenital heart defects are the leading non-infectious cause of death in children. Genetic studies in the mouse have been crucial to uncover new genes and signaling pathways associated with heart development and congenital heart disease. The identification of murine models of congenital cardiac malformations in high-throughput mutagenesis screens and in gene-targeted models is hindered by the opacity of the mouse embryo.

Pubmed ID: 15615595

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Associated grants

  • Agency: British Heart Foundation, United Kingdom
    Id: PS/02/002/14893

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Advanced 3D Visualization and Volume Modeling (tool)

RRID:SCR_014305

Software tool for visualizing, manipulating, and understanding data from tomography, microscopy, MRI and other imaging processes.Used to import and export options, to processes 3D image filtering and DTI based fiber tracking to visualization, volume and surface rendering, author tools for virtual reality navigation, video generation, and more.

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