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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
B6.129S-Tnftm1Gkl/J Resource Report Resource Website 10+ mentions Issue |
RRID:IMSR_JAX:005540 | Mus musculus |
B6.129S6-Tnf |
gene symbol note: tumor necrosis factor; mutant strain|congenic strain: Tnf | tumor necrosis factor | targeted mutation 1; George Kollias | JAX:005540 | JAX Mice and Services | JAX | live | 2026-07-24 09:44:00 | 19 | ||||
|
NOD.Cg-Rag1tm1Mom H2-Ab1 Resource Report Resource Website 1+ mentions Issue |
RRID:IMSR_JAX:006022 | Mus musculus |
NOD.Cg-Rag1 |
gene symbol note: CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1; mutant strain|congenic strain: CD4|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell|H2-Ab1|Rag1|CD2|HLA-DQA1|HLA-DQB1 | CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1 | transgene insertion 1; John F Elliott|targeted mutation 1; Michael J Grusby|targeted mutation 1; Peter Mombaerts | JAX:006022 | JAX Mice and Services | JAX | embryo | 2026-07-24 09:44:04 | 1 | ||||
|
NOD.Cg-Rag1tm1Mom H2-Ab1 Resource Report Resource Website Issue |
RRID:IMSR_JAX:006024 | Mus musculus |
NOD.Cg-Rag1 |
gene symbol note: major histocompatibility complex; class II; DQ alpha 1|recombination activating 1|transgene insertion N8; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule|major histocompatibility complex; class II; DQ beta 1; mutant strain|congenic strain: HLA-DQA1|Rag1|Tg(CD4;HLA-DQA1;HLA-DQB1)N8Ell|H2-Ab1|CD4|HLA-DQB1 | major histocompatibility complex; class II; DQ alpha 1|recombination activating 1|transgene insertion N8; John F Elliott|histocompatibility 2; class II antigen A; beta 1|CD4 molecule|major histocompatibility complex; class II; DQ beta 1 | transgene insertion N8; John F Elliott|targeted mutation 1; Peter Mombaerts|targeted mutation 1; Michael J Grusby | JAX:006024 | JAX Mice and Services | JAX | embryo | 2026-07-24 09:44:05 | 0 | ||||
|
NOD.B6-Tg(IghelMD4)4Ccg/DvsJ Resource Report Resource Website Issue |
RRID:IMSR_JAX:006345 | Mus musculus | NOD.IgHEL | gene symbol note: transgene insertion 4; Christopher C Goodnow|Immunoglobulin heavy chain (gamma polypeptide); mutant strain|congenic strain: Tg(IghelMD4)4Ccg|Ighg | transgene insertion 4; Christopher C Goodnow|Immunoglobulin heavy chain (gamma polypeptide) | transgene insertion 4; Christopher C Goodnow | JAX:006345 | JAX Mice and Services | JAX | embryo | 2026-07-24 09:44:07 | 0 | ||||
|
B6;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04918 | Mus musculus | gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04918 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:41 | 0 | |||||
|
C;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04919 | Mus musculus |
C.129S2-Il6 |
gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04919 | RIKEN BioResource Research Center | RBRC | sperm | 2026-07-24 10:21:41 | 0 | ||||
|
B6.Cg-Ighmtm1Cgn Tg(Aicda-cre)9Mbu Gt(ROSA)26Sor Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC05550 | Mus musculus |
B6.Cg-Gt(ROSA)26Sor |
gene symbol note: transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|gene trap ROSA 26; Philippe Soriano|activation-induced cytidine deaminase|; mutant stock: Tg(Aicda-cre)9Mbu|Ighm|Gt(ROSA)26Sor|Aicda| | transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|gene trap ROSA 26; Philippe Soriano|activation-induced cytidine deaminase| | transgene insertion 9; Meinrad Busslinger|targeted mutation 1; University of Cologne|targeted mutation 1; Stuart Orkin|activation-induced cytidine deaminase| | RBRC05550 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:46 | 0 | ||||
|
MSM.MRL-Faslpr/OhnotRbrc Resource Report Resource Website Issue |
RRID:IMSR_RBRC06798 | Mus musculus | gene symbol note: Fas cell surface death receptor; mutant strain: Fas | Fas cell surface death receptor | lymphoproliferation | RBRC06798 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:56 | 0 | |||||
|
MXH51/Mo-lpr/lpr Resource Report Resource Website 1+ mentions Issue |
RRID:IMSR_RBRC11145 | Mus musculus |
MXH51-Fas |
gene symbol note: Fas cell surface death receptor; recombinant congenic: Fas | Fas cell surface death receptor | lymphoproliferation | RBRC11145 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:22:14 | 1 | ||||
|
MRL.Cg-Faslpr Cd180 Resource Report Resource Website Issue |
RRID:IMSR_RBRC02728 | Mus musculus |
MRL.Cg-Cd180 |
gene symbol note: Fas cell surface death receptor|CD180 antigen; mutant strain: Fas|Cd180 | Fas cell surface death receptor|CD180 antigen | lymphoproliferation|targeted mutation 1; Kensuke Miyake | RBRC02728 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:29 | 0 | ||||
|
EOD/ThpNkcRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC02885 | Mus musculus | gene symbol note: Fas cell surface death receptor|accelerated autoimmunity and lymphoproliferation transposition; mutant strain|inbred strain: Fas|Yaa | Fas cell surface death receptor|accelerated autoimmunity and lymphoproliferation transposition | lymphoproliferation|accelerated autoimmunity and lymphoproliferation | RBRC02885 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:30 | 0 | |||||
|
EOD/ThpNkc-Cnocno-II/NkcRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC02886 | Mus musculus | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition|Fas cell surface death receptor|biogenesis of lysosomal organelles complex-1; subunit 4; cappuccino; coisogenic strain|mutant strain: Yaa|Fas|Bloc1s4 | accelerated autoimmunity and lymphoproliferation transposition|Fas cell surface death receptor|biogenesis of lysosomal organelles complex-1; subunit 4; cappuccino | accelerated autoimmunity and lymphoproliferation|lymphoproliferation|cappuccino-II | RBRC02886 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:30 | 0 | |||||
|
SCG/ThpNkcRbrc Resource Report Resource Website Issue |
RRID:IMSR_RBRC03105 | Mus musculus | gene symbol note: Fas cell surface death receptor; inbred strain: Fas | Fas cell surface death receptor | lymphoproliferation | RBRC03105 | RIKEN BioResource Research Center | RBRC | embryo | 2026-07-24 10:21:31 | 0 | |||||
|
C57BL/6-Tg(CAG-hAPP770)Skita Tg(Tek-cre)1Ywa Resource Report Resource Website Issue |
RRID:IMSR_RBRC11808 | Mus musculus | gene symbol note: transgene insertion 1; Masashi Yanagisawa|transgene insertion 1; Shinobu Kitazume; mutant strain: Tg(Tek-cre)1Ywa|Tg(CAG-hAPP770)Skita | transgene insertion 1; Masashi Yanagisawa|transgene insertion 1; Shinobu Kitazume | transgene insertion 1; Masashi Yanagisawa|transgene insertion 1; Shinobu Kitazume | RBRC11808 | RIKEN BioResource Research Center | RBRC | sperm | 2026-07-24 10:22:20 | 0 | |||||
|
C.129(ICR)-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:581 | Mus musculus |
C.129S4(Cg)-Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:581 | Center for Animal Resources and Development | CARD | embryo | 2026-07-24 10:20:53 | 0 | ||||
|
NZB;129(ICR)(C)(NZW)-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:582 | Mus musculus |
STOCK Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:582 | Center for Animal Resources and Development | CARD | embryo | 2026-07-24 10:20:53 | 0 | ||||
|
B6;129(ICR)-Parp1tm1Hsmm Tg(GPT-delta)/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:585 | Mus musculus |
STOCK Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | transgene; National Cancer Center Research Institute|targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:585 | Center for Animal Resources and Development | CARD | embryo | 2026-07-24 10:20:53 | 0 | ||||
|
D2;129-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:584 | Mus musculus |
D2;129S4-Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:584 | Center for Animal Resources and Development | CARD | embryo | 2026-07-24 10:20:53 | 0 | ||||
|
C.129S2(B6)-Ighmtm1Cgn/Mmmh Resource Report Resource Website Issue Issue |
RRID:MMRRC_000205-MU | Mus musculus | Research areas: Cardiovascular, Immunology and Inflammation, Research Tools, Virology; Mutation Type: Targeted Mutation ; Collection: | decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| decreased compact bone thickness [MP:0000135]| enlarged heart [MP:0000274]| increased cell proliferation [MP:0000351]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal spleen morphology [MP:0000689]| enlarged lymph nodes [MP:0000702]| abnormal skin condition [MP:0001191]| abnormal cardiovascular system physiology [MP:0001544]| abnormal humoral immune response [MP:0001800]| arrested B cell differentiation [MP:0001802]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| thymus hypoplasia [MP:0001823]| abnormal antigen presentation [MP:0001835]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| heart inflammation [MP:0001853]| myocarditis [MP:0001856]| kidney inflammation [MP:0001859]| abnormal lymphatic vessel morphology [MP:0001879]| premature death [MP:0002083]| abnormal respiratory system physiology [MP:0002133]| abnormal B cell differentiation [MP:0002144]| abnormal spleen marginal sinus morphology [MP:0002363]| abnormal B lymphocyte antigen presentation [MP:0002453]| decreased immunoglobulin level [MP:0002460]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| tubular nephritis [MP:0002704]| increased urine protein level [MP:0002962]| abnormal cytokine secretion [MP:0003009]| cardiac fibrosis [MP:0003141]| thrombocytopenia [MP:0003179]| small intestinal inflammation [MP:0003306]| increased susceptibility to induced arthritis [MP:0003724]| increased autoantibody level [MP:0003725]| abnormal compact bone morphology [MP:0003797]| abnormal PR interval [MP:0003901]| insulitis [MP:0004031]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased spleen weight [MP:0004953]| increased osteoclast cell number [MP:0004984]| increased T cell number [MP:0005015]| decreased B cell number [MP:0005017]| abnormal response to infection [MP:0005025]| increased susceptibility to parasitic infection [MP:0005027]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| cachexia [MP:0005150]| decreased susceptibility to injury [MP:0005166]| abnormal pancreatic islet morphology [MP:0005215]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005559]| increased circulating glucose level [MP:0005616]| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]| abnormal T cell number [MP:0008071]| absent B cells [MP:0008075]| decreased CD4-positive [MP:0008079]| alpha beta T cell number [MP:0008127]| decreased CD8-positive [MP:0008171]| alpha-beta T cell number [MP:0008201]| decreased dendritic cell number [MP:0008211]| abnormal mature B cell morphology [MP:0008212]| absent follicular dendritic cells [MP:0008213]| decreased mature B cell number [MP:0008240]| absent mature B cells [MP:0008241]| absent immature B cells [MP:0008401]| abnormal spleen marginal zone macrophage morphology [MP:0008470]| abnormal metallophilic macrophage morphology [MP:0008495]| abnormal CD8 positive [MP:0009346]| alpha-beta intraepithelial T cell morphology [MP:0010965]| abnormal spleen B cell follicle morphology [MP:0012431] | Ighm | 000205-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10553048 | MMRRC_205-MU, MMRRC_000205, MMRRC_25 | 2026-07-25 09:35:01 | 0 | |||
|
B6.129-Tcrbtm1Mom Ifngtm1Ts/Mmnc Resource Report Resource Website Issue |
RRID:MMRRC_000337-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000938]| motor neuron degeneration [MP:0001219]| thick epidermis [MP:0001243]| abnormal dermal layer morphology [MP:0001263]| weight loss [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002144]| abnormal B cell differentiation [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002816]| colitis [MP:0003691]| abnormal microglial cell physiology [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0004939]| increased anti-chromatin antibody level [MP:0004947]| abnormal B cell morphology [MP:0005014]| skin inflammation [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005017]| decreased lymphocyte cell number [MP:0005018]| decreased B cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0008075]| decreased double-positive T cell number [MP:0008079]| decreased CD4-positive [MP:0008098]| alpha beta T cell number [MP:0008173]| decreased CD8-positive [MP:0008181]| alpha-beta T cell number [MP:0008188]| decreased plasma cell number [MP:0008210]| increased follicular B cell number [MP:0008214]| increased marginal zone B cell number [MP:0008495]| abnormal transitional stage B cell morphology [MP:0009925]| increased mature B cell number [MP:0010229]| increased immature B cell number [MP:0010286]| decreased IgG1 level [MP:0011320]| increased transitional stage T2 B cell number [MP:0011427]| increased transitional stage T3 B cell number [MP:0020519]| increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466] | |Tcrb||Ifngr2 | 000337-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:1359428 PMID:11705890 |
MMRRC_337-UNC, MMRRC_000337, MMRRC_337 | 2026-07-25 09:35:02 | 0 |
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