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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Corpus Callosum Thickness Profile Analysis Pipeline
 
Resource Report
Resource Website
Corpus Callosum Thickness Profile Analysis Pipeline (RRID:SCR_003575) ccsegthickness software resource An end-to-end pipeline for corpus callosum processing that provides automated midsagittal alignment, CC segmentation with a quality control tool, and thickness profile generation. Groupwise analysis is facilitated by permutation testing with FWER and FDR multiple comparison correction. Results display is facilitated by a display script that shows p-values on a 3D pipe representation of a CC. This pipeline is implemented in MATLAB and requires the Image Processing Toolbox. There are plans to implement it completely in Python. linux, matlab, mr, nifti-1, posix/unix-like, corpus callosum is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) PMID:24968872 GNU General Public License nlx_157716 SCR_003575 2026-07-25 12:05:40 0
CIGAL
 
Resource Report
Resource Website
1+ mentions
CIGAL (RRID:SCR_002232) CIGAL software resource Software program that provides accurate real-time stimulus control, behavioral and physiological recording, and synchronization with external devices. It can also provide continuous real-time feedback of task performance and physiological responses. Task programming typically involves a simple text file specifying basic parameter settings (e.g. screen color) and a list of stimulus events, which can include images, animated movies, sound files, text stimuli, video graphics, or commands that communicate with external hardware devices. Multiple video and auditory stimuli can be presented simultaneously. Multi-channel response recording and real-time feedback features require no user programming. Advanced users can add customized stimulus events using CIGAL's real-time programming capabilities. Output files can be automatically created in a variety of output formats (e.g. FSL 3-column files, XML Events files, CSV trial tables). magnetic resonance, stimulus control, behavioral recording, physiological recording is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Duke University; North Carolina; USA
Free, Available for download, Freely available nlx_155528 http://www.nitrc.org/projects/cigal http://fourier.biac.duke.edu/wiki/doku.php/jvs:cigal SCR_002232 Compilable Imaging Graphics and Analytical Language 2026-07-25 12:05:19 6
4D Atlases Construction
 
Resource Report
Resource Website
1+ mentions
4D Atlases Construction (RRID:SCR_002227) software resource Software package for constructing longitudinal atlases, which are the necessary steps for many brain-related applications. magnetic resonance, altas, brain, software package is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of North Carolina at Chapel Hill School of Medicine; North Carolina; USA
PMID:34891818
PMID:31115143
Free, Available for download, Freely available nlx_155688 http://www.nitrc.org/projects/atlas4d http://www.med.unc.edu/bric/ideagroup/free-softwares/4d-atlases-construction SCR_002227 4D Atlas Construction Toolbox, 4D Atlas Construction 2026-07-25 12:05:18 1
Multi-Modal MRI Reproducibility Resource
 
Resource Report
Resource Website
10+ mentions
Multi-Modal MRI Reproducibility Resource (RRID:SCR_002442) Multi-Modal MRI Reproducibility Resource image collection, data or information resource Scan-rescan imaging sessions on 21 healthy volunteers (no history of neurological disease) intended to be a resource for statisticians and imaging scientists to be able to quantify the reproducibility of their imaging methods using data available from a generic 1 hour session at 3T. Imaging modalities include MPRAGE, FLAIR, DTI, resting state fMRI, B0 and B1 field maps, ASL, VASO, quantitative T1 mapping, quantitative T2 mapping, and magnetization transfer imaging. All data have been converted to NIFTI format. Please cite: Bennett. A. Landman, Alan J. Huang, Aliya Gifford, Deepti S. Vikram, Issel Anne L. Lim, Jonathan A.D. Farrell, John A. Bogovic, Jun Hua, Min Chen, Samson Jarso, Seth A. Smith, Suresh Joel, Susumu Mori, James J. Pekar, Peter B. Barker, Jerry L. Prince, and Peter C.M. van Zijl. ?Multi-Parametric Neuroimaging Reproducibility: A 3T Resource Study?, NeuroImage. (2010) NIHMS/PMC:252138 doi:10.1016/j.neuroimage.2010.11.047 java image science toolkit, magnetic resonance, nifti, neuroimaging, reproducibility, mprage, flair, dti, resting state fmri, b0 field map, b1 field map, asl, vaso, quantitative t1 mapping, quantitative t2 mapping, magnetization transfer imaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: JIST: Java Image Science Toolkit
Healthy PMID:21094686 Free, Available for download, Freely available nlx_155818 SCR_002442 2026-07-25 12:05:26 11
Multicomponent T2 estimation with stimulated echo correction
 
Resource Report
Resource Website
Multicomponent T2 estimation with stimulated echo correction (RRID:SCR_002446) Multicomponent T2 estimation with stimulated echo correction software resource Software tool designed to assist users in the estimation of multiple relaxation components from MRI T2 weighted spin-echo data such as that produced by a Carr-Purcell-Meiboom-Gill (CPMG) sequence. This problem is important to study myelin content in white matter diseases such as multiple sclerosis. Stimulated echoes arising from non-ideal flip angles are accounted for using the Extended Phase Graph (EPG) algorithm. The distribution is modelled as a small number of discrete components and a Bayesian estimation algorithm is provided to determine the weights and locations of the components as well as the actual flip angle. This algorithm outperforms iterative gradient descent based approaches. algorithm, matlab, magnetic resonance, mri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) PMID:23629849 Free, Available for download, Freely available nlx_155820 SCR_002446 2026-07-25 12:05:27 0
COGNISION
 
Resource Report
Resource Website
1+ mentions
COGNISION (RRID:SCR_002362) COGNISION software resource A portable, highly integrated, internet-enabled, hardware / software platform and patient management system, which includes an online Patient Manager module which complies with the HIPAA Final Security Rule, an event-related potential (ERP) Viewer module to view and analyze raw and average ERP waves, and a Protocol Editor module to simplify the choice and administration of selected ERP protocols. It is also easy to train and administer with non-specialized personnel, and is designed to be used in an out-patient setting. COGNISION TM with auditory or visual event-related potential (ERP) technology, provides a direct physiologic measure of patients' cognitive processing (i.e., a cognitive biomarker). eeg, eeg, meg, electrocorticography, event-related potentials, hardware, physiological recording, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial License nlx_155724 http://www.nitrc.org/projects/neuronetrix SCR_002362 COGNISION (TM) System 2026-07-25 12:05:21 2
NiBabel
 
Resource Report
Resource Website
100+ mentions
NiBabel (RRID:SCR_002498) NiBabel software resource A Python package for reading and writing a variety of medical and neuroimaging file formats. This includes: ANALYZE (plain, SPM99, SPM2), NIfTI1, as well as MINC. NiBabel is the successor of PyNIfTI. magnetic resonance, python, neuroimaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: PyNIfTI
is related to: MNE software
has parent organization: Neuroimaging in Python
Free, Available for download, Freely available nlx_155896 http://www.nitrc.org/projects/nibabel SCR_002498 NIPY File IO 2026-07-25 12:05:23 122
Pythagorean Displacement and Motion Regressors
 
Resource Report
Resource Website
1+ mentions
Pythagorean Displacement and Motion Regressors (RRID:SCR_002525) Pythagorean Displacement and Motion Regressors software resource Matlab script that uses the Pythagorean Theorem to calculate head motion and position, while preserving degrees of freedom. The motion parameters output by SPM (rp*.txt) estimate head position relative to the first volume in 3D translation and 3D rotation, which are often entered as a nuisance regressor during individual-level statistics. Regressing the total displacement and relative position can potentially explain more variance in voxel-level BOLD signals that is related to head movement during an fMRI experiment. algorithm, magnetic resonance, matlab, pythagorean theorem, head, motion, position, fmri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155931 SCR_002525 2026-07-25 12:05:29 5
Signed Differential Mapping
 
Resource Report
Resource Website
100+ mentions
Signed Differential Mapping (RRID:SCR_002554) SDM software resource Statistical method and software for conducting image- and coordinate-based meta-analysis of neuroimaging studies investigating differences in brain activity (e.g. BOLD response in fMRI, metabolism in PET) or structure (e.g. gray matter volume in VBM, voxel-based or TBSS white matter fractional anisotropy in DTI, etcetera). magnetic resonance, pet, spect, fmri, vbm, meta-analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155962 http://www.nitrc.org/projects/sdm SCR_002554 2026-07-25 12:05:25 150
Triangle BioSystems
 
Resource Report
Resource Website
10+ mentions
Triangle BioSystems (RRID:SCR_002603) TBSI commercial organization THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. A biomedical device company focused on developing and manufacturing neural hardware solutions for application in medical research using animals when bio-monitoring, recording and stimulation functions are needed. * Neural Recording Equipment * Neural Stimulation Equipment * Data Acquisition Hardware and Software computational neuroscience, eeg, eeg, meg, electrocorticography, hardware, other software resource, physiological recording, software is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) THIS RESOURCE IS NO LONGER IN SERVICE nlx_156006 http://www.nitrc.org/projects/tbsi SCR_002603 Triangle BioSystems International 2026-07-25 12:05:30 11
TetraMetrix
 
Resource Report
Resource Website
1+ mentions
TetraMetrix (RRID:SCR_002601) TetraMetrix software resource An open-source software project for distributed Tetrahedral Mesh Modeling and Analysis (TMMA) of multidimensional data. Tetrahedra are 3D, space filling, geometric objects that can be used to form representations and partitions of objects like volumes and shapes obtained from biomedical images (e.g., 3D MRI brain images). Tetrahedra are a natural extension of lines (1D) and surface triangulations (2D) which enable finite element analysis of irregular shapes, and permit a greater range of morphometric characterization of multidimensional objects. A beta version of the program is available for download. Please see the very brief instructions on the "Docs" tab on the left. magnetic resonance, 3d, mri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Laboratory of Neuro Imaging
Free, Available for download, Freely available nlx_156004 SCR_002601 2026-07-25 12:05:25 1
PennCNV
 
Resource Report
Resource Website
100+ mentions
PennCNV (RRID:SCR_002518) PennCNV software resource A free software tool for Copy Number Variation (CNV) detection from SNP genotyping arrays. Currently it can handle signal intensity data from Illumina and Affymetrix arrays. With appropriate preparation of file format, it can also handle other types of SNP arrays and oligonucleotide arrays. PennCNV implements a hidden Markov model (HMM) that integrates multiple sources of information to infer CNV calls for individual genotyped samples. It differs form segmentation-based algorithm in that it considered SNP allelic ratio distribution as well as other factors, in addition to signal intensity alone. In addition, PennCNV can optionally utilize family information to generate family-based CNV calls by several different algorithms. Furthermore, PennCNV can generate CNV calls given a specific set of candidate CNV regions, through a validation-calling algorithm. imaging genomics, copy number variation, snp, genotyping array, array, oligonucleotide, hidden markov model, genotype, genome is listed by: OMICtools
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: VegaMC
is related to: OpenBioinformatics.org
has parent organization: University of Pennsylvania; Philadelphia; USA
NIMH MH604687 PMID:17921354 Free OMICS_00729, nlx_155921 http://www.openbioinformatics.org/penncnv/
http://www.neurogenome.org/cnv/penncnv SCR_002518 PennCNV: copy number variation detection 2026-07-25 12:05:28 349
Web Interfaces for Multiscale Images
 
Resource Report
Resource Website
Web Interfaces for Multiscale Images (RRID:SCR_002589) Web Interfaces for Multiscale Images knowledge environment THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 13, 2026. Venue for discussing and defining standard web interfaces for sharing images, annotations, and analyses of multiscale biological images. The goal is to increase interoperability of code to share the burden of infrastructure, increase code reuse, and allow us to spend more time focused on scientific questions. Please visit our Wiki to start participating. Together we can develop a small group of interfaces which are easy to implement, extensible, and cover the major tasks of developing tools for multiscale data on the web. magnetic resonance, interoperability, microscopy, standard specification, forum is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) THIS RESOURCE IS NO LONGER IN SERVICE nlx_156020 SCR_002589 2026-07-25 12:05:26 0
OEI: fMRI compatible olfactometer
 
Resource Report
Resource Website
1+ mentions
OEI: fMRI compatible olfactometer (RRID:SCR_002507) OEI fMRI compatible olfactometer instrument resource A computerized, odor delivery device that can be used for basic research applications including mapping olfactory centers, cognitive / learning research, neuro-marketing among other uses. Additional products including tests for odor threshold, odor identification, odor discrimination and odor memory. experiment control, hardware, magnetic resonance, stimulus presentation, odor, olfactory, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial License https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_002507.pdf nlx_155907 http://www.nitrc.org/projects/oei, http://www.osmicenterprises.com/docs/OsmicFMRIOlfactomterManual%207-1-13.pdf SCR_002507 2026-07-25 12:05:24 4
Faceted Search Based Ontology Visualizer
 
Resource Report
Resource Website
Faceted Search Based Ontology Visualizer (RRID:SCR_000124) ontologyviz software resource Software that allows user to do faceted search on an ontology and enables visualization of the search results on the 3D digital atlas. Currently supports faceted search of functional neuroanatomy. computational neuroscience, magnetic resonance, ontology, functional neuroanatomy, facet, visualization is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Freely available nlx_155874 SCR_000124 2026-07-25 12:04:36 0
Scribe
 
Resource Report
Resource Website
Scribe (RRID:SCR_000423) Scribe software resource Scribe encodes papers to populate the BrainMap Database magnetic resonance, pet, spect is used by: brainmap.org
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
Free, Freely available nlx_155958 SCR_000423 2026-07-25 12:04:45 0
BASH4RfMRI
 
Resource Report
Resource Website
BASH4RfMRI (RRID:SCR_005970) software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented July 23, 2015. Of note: most functions have been integrated in 1000 Functional Connectomes Project (www.nitrc.org/projects/fcon_1000). This package is not updated, thus please visit 1000 Functional Connectomes Project site and download relevant bash scripts. BASH Scripts for a resting-state functional MRI study. The functions include seed-based correlation analysis, amplitude analysis and independent component analysis. Note: this tool is just a plug-in for FSL, AFNI and FreeSurfer. Thus, you need have them before you use BASH4RfMRI. algorithm or reusable library, information theory, spectral analysis, correlation, multivariate analysis, platform or development environment, magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: FSL
is related to: Analysis of Functional NeuroImages
is related to: FreeSurfer
is related to: 1000 Functional Connectomes Project
THIS RESOURCE IS NO LONGER IN SERVICE nlx_151343 SCR_005970 BASH Scripts, bash-rs-fcmri 2026-07-25 12:06:12 0
NiftySim
 
Resource Report
Resource Website
1+ mentions
NiftySim (RRID:SCR_006591) NiftySim software resource A high-performance nonlinear finite element solver. A key feature is the option of GPU-based execution, which allows the solver to significantly out-perform equivalent commercial packages. pet, spect is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University College London; London; United Kingdom
BSD License nlx_155900 http://www.nitrc.org/projects/niftysim SCR_006591 Nifty Sim 2026-07-25 12:06:26 3
Web Game for Collaborative Labeling
 
Resource Report
Resource Website
1+ mentions
Web Game for Collaborative Labeling (RRID:SCR_006685) Web Game for Collaborative Labeling software resource Web game that provides an innovative infrastructure for labeling to enable an alternative to expert raters for medical image labeling through statistical analysis of the collaborative efforts of many, minimally-trained raters. Statistical atlases of regional brain anatomy have proven to be extremely useful in characterizing the relationship between the structure and function of the human nervous system. Typically, an expert human rater manually examines each slice of a three-dimensional volume. This approach can be exceptionally time and resource intensive, so cost severely limits the clinical studies where subject-specific labeling is feasible. Methods for improved efficiency and reliability of manual labeling would be of immense benefit for clinical investigation into morphological correlates of brain function. magnetic resonance, labeling, crowdsourcing is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) GNU Lesser General Public License nlx_156019 http://www.nitrc.org/projects/webmill SCR_006685 2026-07-25 12:06:25 2
POLGUI - Matlab Polhemus Interface
 
Resource Report
Resource Website
1+ mentions
POLGUI - Matlab Polhemus Interface (RRID:SCR_006752) POLGUI software resource An interface between MATLAB and the Polhemus Fastrak digitizer used to digitize fiducial locations and scalp EEG electrode locations. There are 5 versions all of which work under MATLAB R14 (on both linux and windows platforms), # polgui_ver1_r14 : works with 1 receiver (stylus pen) # polgui_ver2_r14 : works with 2 receivers (including the pen) # polgui_ver3_r14 : works with 3 receivers(including the pen) # polgui_ver4_r14 : works with 4 receivers (including the pen) # polgui_ver5_r14 : Generic version which works with 1/2/3/4 receivers (WARNING: Ver 5 might be buggy; not fully tested) Requirements: MATLAB R14 (Linux/Windows) eeg, meg, electrocorticography, linux, matlab, microsoft, magnetic resonance, posix/unix-like, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
BSD License nlx_155915 http://www.nitrc.org/projects/polgui SCR_006752 POLGUI - Matlab GUI for Polhemus Fastrak 2026-07-25 12:06:30 4

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