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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
sapFinder
 
Resource Report
Resource Website
sapFinder (RRID:SCR_002685) software resource An R software package, for detection of the variant peptides based on tandem mass spectrometry (MS/MS)-based proteomics data. It automates (1) variation-associated database construction, (2) database searching, (3) post-processing, (4) HTML-based report generation in shotgun proteomics. standalone software, r, mass spectrometry, proteomics, rna-seq, report writing, snp, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25053745 Free, Available for download, Freely available biotools:sapfinder, OMICS_05285 https://bio.tools/sapfinder SCR_002685 sapFinder - A package for variant peptides detection and visualization in shotgun proteomics. 2026-09-19 12:50:03 0
leeHom
 
Resource Report
Resource Website
50+ mentions
leeHom (RRID:SCR_002710) software resource Software program for the Bayesian reconstruction of ancient DNA fragments. The algorithm removes the adaptors and reconstructs the original DNA sequences using a Bayesian maximum a posteriori probability approach. standalone software, illumina, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25100869 Free, Available for download, Freely available biotools:leehom, OMICS_05254 https://bio.tools/leehom SCR_002710 2026-09-19 12:50:03 59
ANDES
 
Resource Report
Resource Website
10+ mentions
ANDES (RRID:SCR_002791) data analysis software, data processing software, software application, software resource, software toolkit Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses. deep sequencing, biomarker detection, statistical analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:20633290 Free, Freely available, Available for download biotools:andes, OMICS_01119 https://bio.tools/andes SCR_002791 Statistical tools for the Analyses of Deep Sequencing (ANDES), Statistical tools for the Analyses of Deep Sequencing, Statistical tools for the ANalyses of Deep Sequencing 2026-09-19 12:50:05 26
NCBI database of Genotypes and Phenotypes (dbGap)
 
Resource Report
Resource Website
500+ mentions
NCBI database of Genotypes and Phenotypes (dbGap) (RRID:SCR_002709) dbGaP data or information resource, data repository, database, service resource, storage service resource Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits. clinical, trial, genotype, interaction, homology, cell, morphology, interaction, phenotype, molecular diagnosis, genetic recombination, gold standard, bio.tools is used by: International Genomics of Alzheimers Project
is used by: NIDDK Inflammatory Bowel Disease Genetics Consortium
is used by: NIH Heal Project
is used by: Genomic Data Commons Data Portal (GDC Data Portal)
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: NIDDK Central Repository
is related to: eMERGE Network: electronic Medical Records and Genomics
is related to: Framingham Heart Study
is related to: PhenoExplorer
is related to: Chronic Renal Insufficiency Cohort Study
is related to: DbGaP Cleaner
is related to: Psychiatric Genomics Consortium
is related to: ISCA Consortium
is related to: Allen Institute for Brain Science
has parent organization: NCBI
is parent organization of: Resource for Genetic Epidemiology Research on Adult Health and Aging
NLM PMID:24297256
PMID:17898773
Restricted nif-0000-23342, OMICS_00263, biotools:dbgap, r3d100010788 http://www.ncbi.nlm.nih.gov/sites/entrez?db=gap, https://bio.tools/dbgap, https://doi.org/10.17616/R3GS4K SCR_002709 database of Genotypes and Phenotypes (dbGaP), dbGaP, NCBI, Database of Genotypes and Phenotypes 2026-09-19 12:50:03 736
Pathview
 
Resource Report
Resource Website
500+ mentions
Pathview (RRID:SCR_002732) software resource A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. software package, r, differential expression, gene expression, gene set enrichment, genetics, graph, network, metabolomics, microarray, pathway, proteomics, rna-seq, sequencing, systems biology, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23740750 Free, Freely available, Available for download biotools:pathview, OMICS_05212 http://pathview.r-forge.r-project.org/, https://bio.tools/pathview SCR_002732 path view 2026-09-19 12:50:04 569
SuperPred: Drug classification and target prediction
 
Resource Report
Resource Website
10+ mentions
SuperPred: Drug classification and target prediction (RRID:SCR_002691) SuperPred data access protocol, data or information resource, database, software resource, web service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 24,2025. Publicly available web-server to predict medical indication areas based on properties and similarity of chemical compounds. The web-server translates a user-defined molecule into a structural fingerprint that is compared to about 6300 drugs, which are enriched by 7300 links to molecular targets of the drugs, derived through text mining followed by manual curation. Links to the affected pathways are provided. The similarity to the medical compounds is expressed by the Tanimoto coefficient that gives the structural similarity of two compounds. A similarity score higher than 0.85 results in correct ATC prediction for 81% of all cases. As the biological effect is well predictable, if the structural similarity is sufficient, the web-server allows prognoses about the medical indication area of novel compounds and to find new leads for known targets. The combination of physicochemical property and similarity searching provides the possibility to detect new biologically active compounds and novel targets for drug-like compounds. SuperPred can be applied for drug repositioning purposes, too. A further intention of SuperPred is to find side effects elicited by drugs caused through off-target hits. drug, drug class, drug target, addiction, anatomical therapeutic chemical, application area, biological activity, chemical, chemical classification, chemical property, classification, compound, molecular target, molecule, nervous system, pathway, pharmacological property, physicochemical property, prediction, activity spectra, substance, structural similarity, structure, tanimoto coefficient, tanimoto score, target prediction, target-prediction server, therapeutic approach, therapeutic property, drug classification, target prediction, similarity score, target, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Charite - Universitatsmedizin Berlin; Berlin; Germany
SFB 449 ;
IRTG Berlin-Boston-Kyoto and Deutsche Krebshilfe. ;
DFG
PMID:18499712
PMID:24878925
THIS RESOURCE IS NO LONGER IN SERVICE biotools:superpred, nif-0000-00415 https://bio.tools/superpred SCR_002691 2026-09-19 12:50:06 10
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) data analysis software, data processing software, sequence analysis software, software application, software resource Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow, https://sources.debian.org/src/bio-rainbow/ SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-09-19 12:50:04 41
Coding Potential Calculator
 
Resource Report
Resource Website
100+ mentions
Coding Potential Calculator (RRID:SCR_002764) CPC analysis service resource, data analysis service, production service resource, service resource, software resource A Support Vector Machine-based classifier to assesses the protein-coding potential of a transcript based on six biologically meaningful sequence features. CPC can discriminate coding from noncoding transcripts with high accuracy and speed. In addition to predicting the coding potential of the input transcripts, the CPC web server also graphically displays detailed sequence features and additional annotations of the transcript that may facilitate users' further investigation. The coding potential calculator tool reads FASTA data format as input. fasta, transcript, protein coding, coding potential, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Peking University; Beijing; China
PMID:17631615 Free, Freely available biotools:cpc, rid_000106 https://bio.tools/cpc SCR_002764 2026-09-19 12:50:05 225
rBiopaxParser
 
Resource Report
Resource Website
1+ mentions
rBiopaxParser (RRID:SCR_002744) software resource A software package that provides a comprehensive set of functions for parsing, viewing and modifying BioPAX pathway data within R. At the moment BioPAX level 2 and level 3 are supported. software package, mac os x, unix/linux, windows, data representation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23274212 Free, Freely available, Available for download biotools:rbiopaxparser, OMICS_05211 https://github.com/frankkramer/rBiopaxParser, https://bio.tools/rbiopaxparser SCR_002744 rBiopaxParser - Parses BioPax files and represents them in R 2026-09-19 12:50:04 4
hot scan
 
Resource Report
Resource Website
1+ mentions
hot scan (RRID:SCR_002840) software resource A free software to detect genomic regions unusually rich in translocation breakpoints. More generally, it may be used to detect a region that is unusually rich in a given character of a binary sequence. software package, perl, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24860160 Free, Freely available, Available for download biotools:hot_scan, OMICS_05200 https://bio.tools/hot_scan SCR_002840 hot_scan 2026-09-19 12:50:06 6
GreenPhylDB
 
Resource Report
Resource Website
10+ mentions
GreenPhylDB (RRID:SCR_002834) GreenPhylDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource A database designed for plant comparative and functional genomics based on complete genomes. It comprises complete proteome sequences from the major phylum of plant evolution. The clustering of these proteomes was performed to define a consistent and extensive set of homeomorphic plant families. Based on this, lists of gene families such as plant or species specific families and several tools are provided to facilitate comparative genomics within plant genomes. The analyses follow two main steps: gene family clustering and phylogenomic analysis of the generated families. Once a group of sequences (cluster) is validated, phylogenetic analyses are performed to predict homolog relationships such as orthologs and ultraparalogs. comparative genomics, genome, functional genomics, genomics, gene family, homolog, bio.tools uses: Gene Ontology
is listed by: bio.tools
is listed by: Debian
has parent organization: CIRAD
PMID:20864446 Free, Freely available, Available for download biotools:greenphyldb, nif-0000-02928 http://greenphyl.cirad.fr, http://www.greenphyl.org/v3/, https://bio.tools/greenphyldb SCR_002834 2026-09-19 12:50:10 20
Cancer Genome Anatomy Project
 
Resource Report
Resource Website
100+ mentions
Cancer Genome Anatomy Project (RRID:SCR_003072) CGAP data or information resource, portal, topical portal Project to determine the gene expression profiles of normal, precancer, and cancer cells, whose generated resources are available to the cancer community. Interconnected modules provide access to all CGAP data, bioinformatic analysis tools, and biological resources allowing the user to find in silico answers to biological questions in a fraction of the time it once took in the laboratory. * Genes * Tissues * Pathways * RNAi * Chromosomes * SAGE Genie * Tools gene, gene expression, normal cell, precancer cell, cancer cell, cell, genome, anatomy, gene expression profile, tissue, pathway, rnai, chromosome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: National Cancer Institute
is parent organization of: CGAP GO Browser
Cancer, Normal, Precancer NCI Free, download Freely available biotools:cgap, nif-0000-30468 https://mitelmandatabase.isb-cgc.org/mb_search SCR_003072 Cancer Genome Anatomy Project (CGAP) 2026-09-19 12:50:11 108
Primer3Plus
 
Resource Report
Resource Website
1000+ mentions
Primer3Plus (RRID:SCR_003081) Primer3Plus analysis service resource, data analysis service, production service resource, service resource, software resource, source code A web interface to the Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. primer, dna sequence, primer design, perl, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Primer3
has parent organization: Wageningen University and Research Centre; Gelderland; Netherlands
Howard Hughes Medical Institute ;
NHGRI R01-HG00257;
NHGRI P50-HG00098
PMID:17485472 Free, Freely available biotools:primer3plus, OMICS_02347 https://bio.tools/primer3plus SCR_003081 Primer3Plus - pick primers from a DNA sequence 2026-09-19 12:50:11 1860
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-09-19 12:50:10 4
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-09-19 12:50:09 47
DIALIGN
 
Resource Report
Resource Website
10+ mentions
DIALIGN (RRID:SCR_003041) DIALIGN analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, web service Tool for multiple sequence alignment using various sources of external information that is particularly useful to detect local homologies in sequences with low overall similarity. While standard alignment methods rely on comparing single residues and imposing gap penalties, DIALIGN constructs pairwise and multiple alignments by comparing entire segments of the sequences. No gap penalty is used. This approach can be used for both global and local alignment, but it is particularly successful in situations where sequences share only local homologies. Several versions of DIALIGN are available online at GOBICS, http://dialign.gobics.de/ dna, protein, sequence alignment, sequence, alignment, fasta, genome, genomic sequence, homology, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Bielefeld University; North Rhine-Westphalia; Germany
PMID:15215344
PMID:23620293
DOI:10.1186/1748-7188-3-6
Free, Available for download, Freely available nif-0000-30417, OMICS_24606, OMICS_00973, biotools:dialign-tx http://dialign.gobics.de/, https://bio.tools/dialign-tx https://sources.debian.org/src/dialign-tx/ SCR_003041 DIALIGN at GOBICS 2026-09-19 12:50:10 44
SALT
 
Resource Report
Resource Website
1000+ mentions
SALT (RRID:SCR_003187) SALT software resource Software that can accurately and sensitivity classify short reads of next-generation sequencing (NGS) into protein domain families. It is based on profile HMM and a supervised graph contribution algorithm. Compared to existing tools, it has high sensitivity and specificity in classifying short reads into their native domain families. next-generation sequencing, protein, protein domain, short read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23782615 Free, Available for download, Freely available OMICS_01565, biotools:salt https://bio.tools/salt SCR_003187 SALT - Protein domain classifier 2026-09-19 12:50:13 1307
PredictNLS
 
Resource Report
Resource Website
10+ mentions
PredictNLS (RRID:SCR_003133) PredictNLS analysis service resource, data analysis service, production service resource, service resource, software resource Software automated tool for analysis and determination of Nuclear Localization Signals (NLS). Predicts that your protein is nuclear or finds out whether your potential NLS is found in our database. The program also compiles statistics on the number of nuclear/non-nuclear proteins in which your potential NLS is found. Finally, proteins with similar NLS motifs are reported, and the experimental paper describing the particular NLS are given. bio.tools, nuclear localization signal, protein, protein sequence is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: ROSTLAB
has parent organization: Columbia University; New York; USA
DOI:10.1093/embo-reports/kvd092 Free, Available for download, Freely available nif-0000-31416, OMICS_01633, SCR_008553, biotools:predictnls https://www.rdocumentation.org/packages/propagate/versions/1.0-4/topics/predictNLS SCR_003133 Prediction and Analysis of Nuclear Localization Signals 2026-09-19 12:50:12 33
NovelSeq
 
Resource Report
Resource Website
NovelSeq (RRID:SCR_003136) NovelSeq software resource Software pipeline to detect novel sequence insertions using high throughput paired-end whole genome sequencing data. sequence, insertion, genome sequencing, genome, next-generation sequencing, illumina, unix, linux, c, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:20385726 Free, Available for download, Freely available biotools:novelseq, nlx_156791, OMICS_02164 https://mybiosoftware.com/novelseq-1-0-2-sequence-insertions-detection.html#google_vignette SCR_003136 NovelSeq: Novel Sequence Insertion Detection 2026-09-19 12:50:12 0
mrCaNaVaR
 
Resource Report
Resource Website
10+ mentions
mrCaNaVaR (RRID:SCR_003135) mrCaNaVaR software resource Copy number caller that analyzes the whole-genome next-generation sequence mapping read depth to discover large segmental duplications and deletions. It also has the capability of predicting absolute copy numbers of genomic intervals. genome, next-generation sequence, duplication, deletion, copy number variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
Free, Freely available OMICS_02138, nlx_156790, biotools:mrcanavar https://bio.tools/mrcanavar SCR_003135 mrCaNaVaR - micro-read Copy Number Variant Regions, micro-read Copy Number Variant Regions 2026-09-19 12:50:12 16

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