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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Bycom
 
Resource Report
Resource Website
Bycom (RRID:SCR_000659) software resource A software which can perform methylcytosine calling from BS-seq (WGBS and RRBS), and permits either unmapped reads (FASTQ) or mapped reads (SAM/BAM) to be used as the input data. Certain SNPs (C>A/G) can also be selected in the output. methylcytosine, bs-seq, fastq, sam, bam, snps, snp, wgbs, rrbs, sorftw is listed by: OMICtools
has parent organization: SourceForge
PMID:25255082 Free, Available for download, Freely available OMICS_00594 SCR_000659 2026-07-25 12:10:24 0
BamView
 
Resource Report
Resource Website
10+ mentions
BamView (RRID:SCR_004207) BamView software resource, source code A free interactive display of read alignments in BAM data files that can be launched with Java Web Start or downloaded. This interactive Java application for visualizing the large amounts of data stored for sequence reads which are aligned against a reference genome sequence can be used in a number of contexts including SNP calling and structural annotation. It has been integrated into Artemis so that the reads can be viewed in the context of the nucleotide sequence and genomic features. The source code is available as part of the Artemis code which can be downloaded from GitHub. bam, next-generation sequencing, java, snp calling, structural annotation, macosx, unix, windows, visualize, analyze, sequence read, reference sequence, single nucleotide polymorphism, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:22253280
PMID:20071372
GNU General Public License biotools:bamview, OMICS_00878, nlx_22933 https://bio.tools/bamview SCR_004207 2026-07-25 12:13:22 21
ALCHEMY
 
Resource Report
Resource Website
1+ mentions
ALCHEMY (RRID:SCR_005761) ALCHEMY software resource, source code ALCHEMY is a genotype calling algorithm for Affymetrix and Illumina products which is not based on clustering methods. Features include explicit handling of reduced heterozygosity due to inbreeding and accurate results with small sample sizes. ALCHEMY is a method for automated calling of diploid genotypes from raw intensity data produced by various high-throughput multiplexed SNP genotyping methods. It has been developed for and tested on Affymetrix GeneChip Arrays, Illumina GoldenGate, and Illumina Infinium based assays. Primary motivations for ALCHEMY''s development was the lack of available genotype calling methods which can perform well in the absence of heterozygous samples (due to panels of inbred lines being genotyped) or provide accurate calls with small sample batches. ALCHEMY differs from other genotype calling methods in that genotype inference is based on a parametric Bayesian model of the raw intensity data rather than a generalized clustering approach and the model incorporates population genetic principles such as Hardy-Weinberg equilibrium adjusted for inbreeding levels. ALCHEMY can simultaneously estimate individual sample inbreeding coefficients from the data and use them to improve statistical inference of diploid genotypes at individual SNPs. The main documentation for ALCHEMY is maintained on the sourceforge-hosted MediaWiki system. Features * Population genetic model based SNP genotype calling * Simultaneous estimation of per-sample inbreeding coefficients, allele frequencies, and genotypes * Bayesian model provides posterior probabilities of genotype correctness as quality measures * Growing number of scripts and supporting programs for validation of genotypes against control data and output reformating needs * Multithreaded program for parallel execution on multi-CPU/core systems * Non-clustering based methods can handle small sample sets for empirical optimization of sample preparation techniques and accurate calling of SNPs missing genotype classes ALCHEMY is written in C and developed on the GNU/Linux platform. It should compile on any current GNU/Linux distribution with the development packages for the GNU Scientific Library (gsl) and other development packages for standard system libraries. It may also compile and run on Mac OS X if gsl is installed. diploid, genotype, snp, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Cornell University; New York; USA
NSF 0606461 PMID:20926420 GNU General Public License biotools:alchemy, nlx_149227 https://bio.tools/alchemy SCR_005761 ALCHEMY - An automated population genetic model driven SNP genotype calling method 2026-07-25 12:13:24 5
OWL API
 
Resource Report
Resource Website
10+ mentions
OWL API (RRID:SCR_005734) OWL API software resource, source code The OWL API is a Java API and reference implementation for creating, manipulating and serializing OWL Ontologies. The latest version of the API is focused towards OWL 2. The OWLAPI underpins ontology browsing and editing tools and platforms such as SWOOP and Protege4. Note that this API, or any other OWL-based API, can be used without an integrated OWL parser if you download a pre-converted OWL file generated from OBO. See OBO Ontologies List for all OBO ontologies converted to OWL (we do not list the full complement of OWL-based APIs here, only those of direct relevance to GO). The OWL API includes the following components: * An API for OWL 2 and an efficient in-memory reference implementation * RDF/XML parser and writer * OWL/XML parser and writer * OWL Functional Syntax parser and writer * Turtle parser and writer * KRSS parser * OBO Flat file format parser * Reasoner interfaces for working with reasoners such as FaCT++, HermiT, Pellet and Racer Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible ontology, owl, api, java, software library, parser, writer is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: SourceForge
Open unspecified license - Free for academic use; available under either the LGPL or Apache Licenses nlx_149195 SCR_005734 The OWL API, OWLAPI 2026-07-25 12:13:24 15
Neurofitter
 
Resource Report
Resource Website
1+ mentions
Neurofitter (RRID:SCR_005843) Neurofitter software resource, source code Neurofitter is software for parameter tuning of electrophysiological neuron models. It automatically searches for sets of parameters of neuron models that best fit available experimental data, and therefore acts as an interface between neuron simulators, like Neuron or Genesis, and optimization algorithms, like Particle Swarm Optimization, Evolutionary Strategies, etc. neuron, parameter, tuning, electrophysiology, model, neuron simulator, neuron model has parent organization: SourceForge
has parent organization: University of Antwerp; Antwerp; Belgium
has parent organization: Brandeis University; Massachusetts; USA
has parent organization: Okinawa Institute of Science and Technology
Okinawa Institute of Science and Technology PMID:18974796 GNU General Public License, v2 nlx_149366 SCR_005843 2026-07-25 12:13:24 1
OrChem
 
Resource Report
Resource Website
1+ mentions
OrChem (RRID:SCR_008865) OrChem software resource, source code OrChem is an extension for the Oracle 11G database that adds registration and indexing of chemical structures to support fast substructure and similarity searching. The cheminformatics functionality is provided by the Chemistry Development Kit. OrChem provides similarity searching with response times in the order of seconds for databases with millions of compounds, depending on a given similarity cut-off. For substructure searching, it can make use of multiple processor cores on today''s powerful database servers to provide fast response times in equally large data sets. OrChem is an Oracle chemistry plug-in using the Chemistry Development Kit (CDK). The CDK is an open source Java library for Chemoinformatics and Bioinformatics. OrChem is maintained by the chemoinformatics and metabolism team of the European Bioinformatics Institute. Oracle Data cartridges extend the capabilities of the Oracle server. For chemistry various commercial cartridges exist that facilitate searching and analyzing chemical data. OrChem also provides functionality like this, but is not a cartridge. It doesn''t need Oracle''s extensibility architecture because its Java components run as Java stored procedures inside the Oracle standard JVM (Aurora). OrChem is suitable for Oracle 11G and onwards. Starting with Oracle 11g release 1 (11.1) there is a just-in-time(JIT) compiler for Oracle JVM environment. A JIT compiler for Oracle JVM enables much faster execution because it manages the invalidation, recompilation, and storage of code without an external mechanism. This new Oracle feature makes Java classes perform better than before. oracle, chemistry, cdk, similarity search, chemical structure, cheminformatics, bioinformatics, plugin is listed by: 3DVC
has parent organization: SourceForge
has parent organization: European Bioinformatics Institute
PMID:20298521 GNU Lesser General Public License nlx_149252 SCR_008865 2026-07-25 12:13:26 1
iso2mesh
 
Resource Report
Resource Website
10+ mentions
iso2mesh (RRID:SCR_013202) iso2mesh software application, software resource, software toolkit A Matlab / Octave-based mesh generation toolbox designed for easy creation of high quality surface and tetrahedral meshes from 3D volumetric images. It contains a rich set of mesh processing scripts/programs, functioning independently or interfacing with external free meshing utilities. Iso2mesh toolbox can operate directly on 3D binary, segmented or gray-scale images, such as those from MRI or CT scans, making it particularly suitable for multi-modality medical imaging data analysis or multi-physics modeling. matlab, mesh generation, modeling, magnetic resonance, optical imaging, os independent, mri, computed tomography, octave is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
GNU General Public License nlx_155855 http://www.nitrc.org/projects/iso2mesh SCR_013202 2026-07-26 09:05:51 25
PerlPrimer
 
Resource Report
Resource Website
100+ mentions
PerlPrimer (RRID:SCR_012038) software application, software resource A free, open-source GUI software application written in Perl that designs primers for standard PCR, bisulphite PCR, real-time PCR (QPCR) and sequencing. is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:15073005
DOI:10.1093/bioinformatics/bth254
Open unspecified license OMICS_02354 https://sources.debian.org/src/perlprimer/ SCR_012038 PerlPrimer - open-source PCR primer design 2026-07-26 09:05:37 236
MetAssign
 
Resource Report
Resource Website
1+ mentions
MetAssign (RRID:SCR_000092) software application, software resource, standalone software Software that combines information from the mass-to-charge ratio, retention time and intensity of each peak, together with a model of the inter-peak dependency structure, to increase the accuracy of peak annotation. The software has been implemented as part of the mzMatch metabolomics analysis pipeline, which is available for download. peak annotation, peaks probabilistic identifications, is listed by: OMICtools
is listed by: SourceForge
has parent organization: University of Glasgow; Glasgow; United Kingdom
PMID:24916385 Free, Available for download, Freely available OMICS_04679 http://mzmatch.sourceforge.net/ SCR_000092 2026-07-26 09:02:43 1
NGS-Cleaner
 
Resource Report
Resource Website
NGS-Cleaner (RRID:SCR_000574) NGS-Cleaner software application, software resource Software application that provides cleaning of FASTQ/A formatted large DNA sequence files containing multiple short-reads sequences provided by Next Generation Sequencing platforms. next-generation sequencing is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available, OMICS_01166 SCR_000574 2026-07-26 09:02:50 0
OLORIN
 
Resource Report
Resource Website
OLORIN (RRID:SCR_002015) OLORIN software application, software resource An interactive filtering tool for next generation sequencing data coming from the study of large complex disease pedigrees. It integrates gene flow output from Merlin and next generation sequencing data. Users can interactively filter and prioritize variants based on haplotype sharing across different sets of selected individuals and allele frequency in reference datasets. (entry from Genetic Analysis Software) gene, genetic, genomic, java, any platform with java 1.6 or later, next generation sequencing, variant, haplotype, allele frequency, java swing is listed by: OMICtools
is listed by: Genetic Analysis Software
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
has parent organization: SourceForge
PMID:23052039 Free, Available for download, Freely available nlx_154503, OMICS_01556 http://sourceforge.net/p/olorin/ SCR_002015 2026-07-26 09:03:12 0
HAPLOPAINTER
 
Resource Report
Resource Website
10+ mentions
HAPLOPAINTER (RRID:SCR_001710) HaploPainter software application, software resource A pedigree drawing program, suitable in processing haplotype outputs from GENEHUNTER, ALLEGRO, MERLIN, and SIMWALK (entry from Genetic Analysis Software) gene, genetic, genomic, perl, pedigree, haplotype, draw, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:15377505 Free, Freely Available nlx_154062, OMICS_00209, biotools:haplopainter https://bio.tools/haplopainter http://haplopainter.sourceforge.net/html/ManualIndex.htm SCR_001710 2026-07-26 09:03:03 45
Object-Oriented Development Interface for NMR
 
Resource Report
Resource Website
10+ mentions
Object-Oriented Development Interface for NMR (RRID:SCR_005974) ODIN software application, software resource A C++ software framework to develop, simulate and run magnetic resonance sequences on different platforms. analyze, c++, console (text based), dicom, image display, image reconstruction, modeling, magnetic resonance, nifti, os independent, simulation, visualization is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: SourceForge
GNU General Public License nlx_155909 https://sources.debian.org/src/odin/ SCR_005974 Object Oriented Development Interface for NMR, ODIN - Object-Oriented Development Interface for NMR 2026-07-26 09:04:04 15
Mesh-based Monte Carlo (MMC)
 
Resource Report
Resource Website
Mesh-based Monte Carlo (MMC) (RRID:SCR_006950) MMC software application, software resource A Monte Carlo (MC) solver for photon migration in 3D turbid media. Different from existing MC software designed for layered (such as MCML) or voxel-based media (such as MMC or tMCimg), MMC can represent a complex domain using a tetrahedral mesh. This not only greatly improves the accuracy of the solutions when modeling objects with smooth/complex boundaries, but also gives an efficient way to sample the problem domain to use less memory. The current version of MMC support multi-threaded programming and can give a almost proportional speed-up when using multiple CPU cores. c, console (text based), modeling, monte carlo, optical imaging, posix/unix-like is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
GNU General Public License nlx_155810 http://www.nitrc.org/projects/mmc SCR_006950 Mesh-based Monte Carlo 2026-07-26 09:04:19 0
BioMail
 
Resource Report
Resource Website
1+ mentions
BioMail (RRID:SCR_008174) software application, software resource BioMail is a small web-based application for medical researchers, biologists, and anyone who wants to know the latest information about a disease or a biological phenomenon. It is written to automate searching for recent scientific papers in the PubMed Medline database. BioMail is free and will stay free. What does BioMail do? Periodically BioMail does a user-customized Medline search and sends all matching articles recently added to Medline to the users'' e-mail address. HTML-formatted e-mails generated by BioMail can be used to view selected references in medline format (compatible with most reference manager programs). Why is BioMail helpful? If you use Medline, it may be hard to remember when you did your last search. Often you must scan titles you have already seen to be certain you didn''t miss an important reference. BioMail will perform routine searches for you. This program alerts users to all new papers in their fields automatically. It also helps the user to ''refine'' search patterns once and for all. There is no need to wonder: ''What was that great search pattern I used last Saturday?''. All patterns are safe in the database and can be accessed, tuned, or deleted any time. It is also useful for countries where access to the Internet is not yet widely available. If a person has a permanent e-mail address, but only sporadic www access, she/he only needs to fill out a BioMail form once and then will receive new references from Medline continually. articles, journals, medline interface has parent organization: SourceForge nif-0000-21059 SCR_008174 BioMail 2026-07-26 09:04:35 1
MUMmerGPU
 
Resource Report
Resource Website
1+ mentions
MUMmerGPU (RRID:SCR_001200) MUMmerGPU software application, software resource, data processing software Software tool as high throughput DNA sequence alignment program that runs on nVidia G80-class GPUs. Aligns sequences in parallel on video card to accelerate widely used serial CPU program MUMmer. parallel computation 4, high-throughput sequencing, sequence alignment, dna, graphics processing unit is listed by: OMICtools
is related to: MUMmer
has parent organization: SourceForge
has parent organization: University of Maryland; Maryland; USA
NLM R01 LM006845;
NIGMS R01 GM083873
PMID:20161021 Free, Available for download, Freely available OMICS_02151 SCR_001200 High-throughput sequence alignment using Graphics Processing Units 2026-07-26 09:03:00 5
skewer
 
Resource Report
Resource Website
10+ mentions
skewer (RRID:SCR_001151) skewer software application, software resource, data processing software Software program for adapter trimming that is specially designed for processing Illumina paired-end sequences. illumina, unix/linux, c++, adapter trimming, paired-end, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24925680 Free, Available for download, Freely available OMICS_02106, biotools:skewer https://bio.tools/skewer, https://sources.debian.org/src/skewer/, https://github.com/relipmoc/skewer SCR_001151 skewer - A fast and sensitive adapter trimmer for illumina paired-end sequences 2026-07-26 09:03:01 11
UnoSeq
 
Resource Report
Resource Website
1+ mentions
UnoSeq (RRID:SCR_005116) UnoSeq software library, software resource, software toolkit A Java library to analyze next generation sequencing data and especially perform expression profiling in organisms where no well-annotated reference genome exists. java, expression profile, next generation sequencing is listed by: OMICtools
has parent organization: SourceForge
PMID:20194116 OMICS_01296 SCR_005116 UnoSeq - Expression profiling with next generation sequencing without a reference genome 2026-07-27 09:32:12 1
SeqAnt
 
Resource Report
Resource Website
1+ mentions
SeqAnt (RRID:SCR_005186) SeqAnt service resource, data analysis service, analysis service resource, software resource, production service resource A free web service and open source software package that performs rapid, automated annotation of DNA sequence variants (single base mutations, insertions, deletions) discovered with any sequencing platform. Variant sites are characterized with respect to their functional type (Silent, Replacement, 5' UTR, 3' UTR, Intronic, Intergenic), whether they have been previously submitted to dbSNP, and their evolutionary conservation. Annotated variants can be viewed directly on the web browser, downloaded in a tab delimited text file, or directly uploaded in a Browser Extended Data (BED) format to the UCSC genome browser. SeqAnt further identifies all loci harboring two or more coding sequence variants that help investigators identify potential compound heterozygous loci within exome sequencing experiments. In total, SeqAnt resolves a significant bottleneck by allowing an investigator to rapidly prioritize the functional analysis of those variants of interest. annotation, dna sequence variant, single base mutation, insertion, deletion, sequencing, mutation, variant, sequence variant, perl, sequence, genome is listed by: OMICtools
has parent organization: Emory University; Georgia; USA
has parent organization: SourceForge
PMID:20854673 GNU General Public License, v2 OMICS_00182 SCR_005186 SeqAnt - Sequence Annotator 2026-07-27 09:32:13 2
PAZAR
 
Resource Report
Resource Website
10+ mentions
PAZAR (RRID:SCR_005410) PAZAR service resource, database, software resource, storage service resource, data repository, data or information resource Database that unites independently created and maintained data collections of transcription factor and regulatory sequence annotation. The flexible PAZAR schema permits the representation of diverse information derived from experiments ranging from biochemical protein-DNA binding to cellular reporter gene assays. Data collections can be made available to the public, or restricted to specific system users. The data ''boutiques'' within the shopping-mall-inspired system facilitate the analysis of genomics data and the creation of predictive models of gene regulation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, target gene, regulatory sequence, transcription factor profile, annotation, sequence, profile, transcription factor binding profile, chip, chip-seq, gene, cis-regulatory element, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of British Columbia; British Columbia; Canada
has parent organization: SourceForge
PMID:18971253 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00540, biotools:pazar https://bio.tools/pazar SCR_005410 2026-07-27 09:32:16 32

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