Tools   Select Another Resource Report Type

http://www.ninds.nih.gov/research/parkinsonsweb/amr/amr_mice_ucla_repository.htm

THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 26, 2011. Information for depositors Investigators who are willing to share mice with the PD research community through this resource should send an email to PDMice_at_ninds.nih.gov describing the mouse. The submission will be reviewed by the PD Models Repository Oversight Committee and, if accepted, a copy of the MTA will be sent by return email. NINDS is most interested in distributing mice that have been characterized in a peer-reviewed publication, but other models will certainly be considered. The email should describe the following: The protocol for identification from tail DNA. The health report of the mice to be shipped (the report has to be less than 2 months old). Information about the strain and any special needs for care and breeding. Information about any publications involving the mice Certification that mice are not encumbered by continuing intellectual property or other rights to any research, data or discovery utilizing the animals. Information for consumers Investigators desiring to study the mice available through the repository should send a request via email to PDMice_at_ninds.nih.gov. Requests will be reviewed by the PD Models Repository Oversight Committee and priority will be determined on a first come, first served basis; two breeding pairs will typically be shipped to any single requester. As detailed in the MTA, mice are not available for commercial research, including but not limited to drug screening. Neither the creator nor UCLA have a role in the governance of the Repository, and specifically, cannot impose conditions upon availability or distribution. It is anticipated that until the Repository is in a mode of steady state production, requests will be collected and mice distributed as supply allows. The email requesting mice should include: A brief description of the protocol Either a copy of the IACUC approval letter or numberNINDS/UCLA Repository for Parkinson's Disease Mouse Models: One of the most immediate and important benefits of discoveries regarding the genetic or environmental causes of Parkinson's disease (PD) is the subsequent development of animal models wherein therapeutic and/or preventative interventions may be studied. The widespread availability of such models is critically important to making progress against a disorder that affects more than 500,000 Americans at any given time. The National Institute of Neurological Disorders and Stroke (NINDS) fully recognizes the burden placed on investigators by the financial and logistical realities of distributing high demand research resources. Some investigators have deposited their mice with national distribution facilities but many mouse models are not available through such resources. Developing means to facilitate greater sharing of mouse models of PD is one of the goals developed by the PD research community at the July 2002 summit meeting convened by the NIH Director. Accordingly, as part of the effort to accelerate PD research, NINDS and the University of California at Los Angeles (UCLA) created a resource that will distribute transgenic mouse models of human PD that are not yet available through national commercial resources. Investigators who are willing to share mice with the PD research community can simply arrange with NINDS to have the mice deposited at UCLA and investigators desiring to study the mice may arrange with NINDS to obtain two breeding pairs. The process will use Material Transfer Agreements created specifically for this arrangement.

Proper citation: NINDS/UCLA Repository for Parkinson's Disease Mouse Models (RRID:SCR_007319) Copy   

•   Source: SciCrunch Registry

http://www.crash2.lshtm.ac.uk

This is a trial for a large randomised placebo controlled trial among trauma patients with, or at risk of, significant haemorrhage, of the effects of antifibrinolytic treatment on death and transfusion requirement. Sponsors: This resource is supported by UK NIHR Health Technology Assessment programme, Pfizer, BUPA Foundation, and J P Moulton Charitable Foundation. Keyowrds: Trial, Placebo, Drug, Trauma, Haemorrhage, Antifibrinolytic, Treatment, Death, Transfusion,

Proper citation: Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (RRID:SCR_007235) Copy   

•   Source: SciCrunch Registry

http://www.bitplane.com/go/products/autoaligner

Microtomy is a standard technique used for 2D microscopy, but it can also provide the foundation for 3D analysis using AutoAligner. AutoAligner reads a stack of serial sections and automatically aligns the single images, building up a 3D space that can be explored using Imaris. Each image is aligned in translation and rotation relative to its precursor image in the sequence. In addition to a fully automated mode, AutoAligner also provides manual control for neighboring images that are too different from each other for automatic alignment. The visual alignment tool uses fast display techniques for aligning images in real time.

Proper citation: Autoaligner (RRID:SCR_007355) Copy   

•   Source: SciCrunch Registry

http://www.fmritools.org/Activ2000/activ2000.htm

Data analysis software with the following main features: fMRI spatial and temporal pre-processing (gaussian filtering) with motion correction, time slicing and template co-registration ; fMRI multithreaded bloc processing with one or more conditions (up to 999), lateralization index, paradigm design (box-car style with HRF convolution), anatomic coregistration, multiplanar reconstructions, opengl 3D surfacic rendering. DPTools and Activ 2000 are now one single software: DPTools v 3.0 and above. All the features already included in DPTools are available for the fMRI processings (statistics, motion correction, time slicing, aso). DPTools 3.0 can read Siemens Mosaic and Philips REC/PAR files for diffusion / dynamic series, and can export files to SPM99 format. Features: * Images Conversion * Paradigm Creation * Images Pre-Processing * Images Processing * Statistics * Co-registration * 3D * Filming * Loading / Saving * Batch Script * PACS Integration * and more... Activ 2000 is freely downloadable (46 MB)

Proper citation: Activ 2000 (RRID:SCR_007352) Copy   

•   Source: SciCrunch Registry

http://mipgsun.mipg.upenn.edu/~Vnews/

Data-, machine-, and application- independent software system for the visualization and analysis of multidimensional images. This transportable, very inexpensive software system, has capabilities for visualizing, manipulating, and analyzing multidimensional, multimodality image information. It is designed to run on Unix machines under X-windows. It uses a data protocol that is a multidimensional generalization of the ACR-NEMA standards. We have tested it extensively on SGI and Sun workstations and PCs. Other recipients of 3DVIEWNIX have installed it on a variety of platforms including IBM RS6000s, HP700s, and Stardent, all from a single source code version. UNIQUE FEATURES OF 3DVIEWNIX * Transportable - based on UNIX, X-window, and C * Based on multidimensional generalization of ACR-NEMA standards of data representation * Application-independent * Image dimensionality independent * Can handle rigid, non-rigid, static, and dynamic objects and object assemblies * Can handle object information from multiple modalities and longitudinal acquisitions * Multitudes of visualization, manipulation, and analysis methods incorporated * Open software system distributed with source code

Proper citation: 3DViewnix (RRID:SCR_007351) Copy   

•   Source: SciCrunch Registry

http://www.visionnetwork.nei.nih.gov/

The National Eye Institute (NEI) created the VISION Public Information Network for the purpose of communicating with public information officers at NEI grantee institutions. The Network''s primary mission is to work with the NEI in disseminating research results to the national and local media. The Network also works to inform the public of the mission of the National Institutes of Health (NIH) to improve the health of America through medical research. The NEI is part of the NIH, U.S. Department of Health and Human Services (DHHS). General information portal for eye and vision related resources for the public. Sponsors: This resource is supported by the National Eye Institute.

Proper citation: Vision Public Information Network (RRID:SCR_007340) Copy   

•   Source: SciCrunch Registry

http://ncmir.ucsd.edu/downloads/xvoxtrace.shtm

Xvoxtrace enables volume segmentation of tomographic data using manual tracing. This program allows the researcher to outline features on individual planes of the volume while being guided by simultaneous views of the tracing displayed on a volume rendering or tilt-series. Traced contours can be viewed using XDend or used to generate surfaces for viewing in Synu. Basic Requirements:OpenGL, X windows, and Linux platforms : :

Proper citation: Xvoxtrace (RRID:SCR_007377) Copy   

•   Source: SciCrunch Registry

http://nsr.bioeng.washington.edu/

Database of physiological, pharmacological, and pathological information on humans and other organisms and integration through computational modeling. Models include everything from diagrammatic schema, suggesting relationships among elements composing a system, to fully quantitative, computational models describing the behavior of physiological systems and an organism''s response to environmental change. Each mathematical model is an internally self-consistent summary of available information, and thereby defines a working hypothesis about how a system operates. Predictions from such models are subject to test, with new results leading to new models.BR /> A Tool developed for the NSR Physiome project is JSim, an open source, free software. JSim is a Java-based simulation system for building quantitative numeric models and analyzing them with respect to experimental reference data. JSim''s primary focus is in physiology and biomedicine, however its computational engine is quite general and applicable to a wide range of scientific domains. JSim models may intermix ODEs, PDEs, implicit equations, integrals, summations, discrete events and procedural code as appropriate. JSim''s model compiler can automatically insert conversion factors for compatible physical units as well as detect and reject unit unbalanced equations. JSim also imports the SBML and CellML model archival formats. All JSim models are open source. Goals of the Physiome Project: - To develop and database observations of physiological phenomenon and interpret these in terms of mechanism (a fundamentally reductionist goal). - To integrate experimental information into quantitative descriptions of the functioning of humans and other organisms (modern integrative biology glued together via modeling). - To disseminate experimental data and integrative models for teaching and research. - To foster collaboration amongst investigators worldwide, to speed up the discovery of how biological systems work. - To determine the most effective targets (molecules or systems) for therapy, either pharmaceutic or genomic. - To provide information for the design of tissue-engineered, biocompatible implants.

Proper citation: NSR Physiome Project (RRID:SCR_007379) Copy   

•   Source: SciCrunch Registry

http://www.cpan.org

Welcome to CPAN, where you you will find All Things Perl. CPAN is the Comprehensive Perl Archive Network, a large collection of Perl software and documentation. You can begin exploring from either http://www.cpan.org/, http://www.perl.com/CPAN/ or any of the mirrors listed at http://www.cpan.org/SITES.html. Note that CPAN is also the name of a Perl module, CPAN.pm, which is used to download and install Perl software from the CPAN archive. This FAQ covers only a little about the CPAN module and you may find the documentation for it by using perldoc CPAN via the command line or on the web at http://search.cpan.org/dist/CPAN/lib/CPAN.pm. Sponsors: CPAN works with the generosity and cooperation of hundreds of developers, over 100 participating mirrors, funet.fi donating the network bandwidth, storage space and computing power, volunteers who help keep everything together and users whose interest in Perl keep the archive alive and growing. Keywords: Comprehension, Perl, Archive, Software, Documentation,

Proper citation: Comprehensive Perl Archive Network (RRID:SCR_007253) Copy   

•   Source: SciCrunch Registry

http://www.i-mouse.org/

Over recent years, the European Commission has supported an increasing number of functional genomics projects focusing on the use of the laboratory mouse as a model of human disease. (see http://www.prime-eu.org/euromouseiiprojects.htm for a fuller listing of current and recent projects). CASIMIR (Coordination and Sustainability of International Mouse Informatics Resources: http://www.casimir.org.uk) is aimed at recommending standards to allow data sharing and integration between the different projects. CASIMIR spans a number of areas: data representation (in particular the use of shared ontologies), non-semantic, technical issues concerning database compatibility and interoperability, data acquisition, curation and ownership, integration of biological collections and material resources into the data network, and user interactions. As part of the CASIMIR initiative i-mouse.org was created as a common portal to CASIMIR and other resources we hope will be helpful for investigators using the mouse as a model system for humans or systems biologists and geneticists using the mouse as an experimental system. ontology; metadata;

Proper citation: Informatics resources for mouse functional genomics (RRID:SCR_007374) Copy   

•   Source: SciCrunch Registry

http://dblab.duhs.duke.edu/modules/dblabs_topcat/index.php

TOPPCAT stands for T-One weighted Perfusion imaging Parameter CAlculation Toolkit. TOPPCAT creates quantitative maps of Ktrans (volume transfer constant between blood plasma and the extravascular extracellular space) and fPV (fractional plasma volume) from dynamic T1-weighted perfusion images. At the current time, analysis using the method of Patlak plots (most appropriate for first pass dynamic contrast-enhanced MR imaging) is supported. As a preliminary step for the parameter calculation, TOPPCAT also creates maps of T1 and S0 (equilibrium magnetization) from multi-flip angle T1-weighted SPGR (or FLASH) sequences.Daniel P. Barboriak, James R. MacFall, Anthony O. Padua,Gerald E. York, Benjamin L. Viglianti, and Mark W. Dewhirst. Standardized software for calculation of Ktrans and vp from dynamic T1-weighted MR images. Presented at the International Society for Magnetic Resonance in Medicine Workshop on MR in Drug Development: From Discovery to Clinical Therapeutic Trials, McLean VA, April 2004.

Proper citation: T-One weighted Perfusion imaging Parameter CAlculation Toolkit (RRID:SCR_007376) Copy   

•   Source: SciCrunch Registry

http://www.ebi.ac.uk/Tools/emboss/cpgplot/indexhtml

This portal allows for the detection of regions of genomic sequences that are rich in the CpG pattern is important because such regions are resistant to methylation and tend to be associated with genes which are frequently switched on. Regions rich in the CpG pattern are known as CpG islands. The function of the program cpgplot is to plot CpG rich areas, and cpgreport to report all CpG rich regions. The nuclear genomes of vertebrates are mosaics of isochores, very long stretches of DNA that are homogeneous in base composition and are compositionally correlated with the coding sequences that they embed. Isochores can be partitioned in a small number of families that cover a range of GC levels. Program isochore plots GC content over a sequence. Sponsors: This resource is supported by European Bioinformatics Institute. Keywords: Software, Plotting, Pattern, CpG, Gene, Function, Isochore, DNA, Genome, Homogeneous, Coding, Sequence, Family, Sequencing,

Proper citation: EMBOSS CpGPlot/CpGReport/Isochore (RRID:SCR_007254) Copy   

•   Source: SciCrunch Registry

https://bams1.org/

Knowledge management system designed to handle neurobiological information at different levels of organization of vertebrate nervous system. Database and repository for information about neural circuitry, storing and analyzing data concerned with nomenclature, taxonomy, axonal connections, and neuronal cell types. Handles data and metadata collated from original literature, or inserted by scientists that is associated to four levels of organization of vertebrate nervous system. Data about expressed molecules, neuron types and classes, brain regions, and networks of brain regions.

Proper citation: Brain Architecture Management System (RRID:SCR_007251) Copy   

•   Source: SciCrunch Registry

http://www.neurolens.org/NeuroLens/

An integrated environment for the analysis and visualization of functional neuroimages. It is intended to provide extremely fast and flexible image processing, via an intuitive user interface that encourages experimentation with analysis parameters and detailed inspection of both raw image data and processing results. All processing operations in NeuroLens are built around a Plugin architecture, making it easy to extend its functionality. NeuroLens runs on Apple computers based on the G4, G5, or Intel chipsets and running MacOSX 10.4 (Tiger) or later. It is available free for academic and non-profit research use. * Operating System: MacOS * Programming Language: Objective C * Supported Data Format: AFNI BRIK, ANALYZE, COR, DICOM, MGH/MGZ, MINC, Other Format

Proper citation: NeuroLens (RRID:SCR_007372) Copy   

•   Source: SciCrunch Registry

http://casp.sourceforge.net

CASP is a tool to image analysis in comet assay. CASP has been developed to work with either color, or gray-scale images of fluorescence-stained comets saved in TIF format. In its present version CASP does not control a video or CCD camera. Comets stained with silver (dark cells on white background) must be converted into negative images in order to be analysed correctly. An unlimited number of images can be marked, CASP will load them successively into a image view window (see screenshot). Only comets oriented from left (head) to right (tail) can be analysed correctly. The user can adjust various thresholds of sensitivity and save the adjustments for future use. A measurement frame is drawn on the screen and its size adjusted. The adjustments are frozen to prevent accidental modification. The frame is moved onto a cell and measurement is activated. An intensity profile shows up on a profile window together with selected result values (right window on figure 1) and the result can be saved. In addition to such parameter as head radius, tail length etc, the program calculates the tail moment (TM) and the Olive tail moment (OTM). If several cells are present on the same picture, the user can proceed with the measurement of another cell on the same picture or can load a new picture. The saved results can be visualized during the working session in a spreadsheet in view results window. When measurements are terminated, the results can be exported into a text file and imported into a commercial spreadsheet calculation program. CASP is optimized for a 600x800 resolution. Sponsors: This work has been supported by the University of Wroclaw. Keywords: Comet, Assay, Software, Laboratory, Camera, Negative, Cell, Analysis, Image,

Proper citation: CASPLab: Comet Assay Software Project Laboratory (RRID:SCR_007249) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/fiswidgets/

A set of Java libraries for rapidly creating GUIs for software modules (C, C++, Fortan, PERL scripts, etc.), and graphically controlling process flow among them. This allows a GUI to be created for existing image processing and analysis routines, which provides: 1) graphic elements for setting parameters, arguments, etc. (i.e., text dialogs, file browsers, etc.); 2) links to web based documentation; 3) simple point-and-click interface for setting up a path for data flow from one module to another. The purpose of FisWidgets is to provide an integrated and user-friendly environment for using the disparate and growing array of image processing and analysis tools created by different laboratories.

Proper citation: FisWidgets (RRID:SCR_007367) Copy   

•   Source: SciCrunch Registry

http://cardiogenomica.altervista.org/CARDIOGENOMICS/CardioGenomics%20Homepage.htm

The primary goal of the CardioGenomics PGA is to begin to link genes to structure, function, dysfunction and structural abnormalities of the cardiovascular system caused by clinically relevant genetic and environmental stimuli. The principal biological theme to be pursued is how the transcriptional network of the cardiovascular system responds to genetic and environmental stresses to maintain normal function and structure, and how this network is altered in disease. This PGA will generate a high quality, comprehensive data set for the functional genomics of structural and functional adaptation of the cardiovascular system by integrating expression data from animal models and human tissue samples, mutation screening of candidate genes in patients, and DNA polymorphisms in a well characterized general population. Such a data set will serve as a benchmark for future basic, clinical, and pharmacogenomic studies. Training and education are also a key focus of the CardioGenomics PGA. In addition to ongoing journal clubs and seminars, the PGA will be sponsoring symposia at major conferences, and developing workshops related to the areas of focus of this PGA. Information regarding upcoming events can be found in the Events section of this site, and information about training and education opportunities sponsored by CardioGenomics can be found on the Teaching and Education page. The CardioGenomics project came to a close in 2005. This server, cardiogenomics.med.harvard.edu, remains online in order to continue to distribute data that was generated by investigators under the auspices of the CardioGenomics Program for Genomic Applications (PGA). :Sponsors: This resource is supported by The National Heart, Lung and Blood Institute (NHLBI) of the NIH., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: CardioGenomics (RRID:SCR_007248) Copy   

•   Source: SciCrunch Registry

http://www.mediacy.com/imageproplus

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18,2023. Software package to capture, process, measure, analyze and share images and data.

Proper citation: Image Pro Plus (RRID:SCR_007369) Copy   

•   Source: SciCrunch Registry

http://www.bna.org.uk/

The British Neuroscience Association, formerly known as The Brain Research Association, was officially relaunched in 1997, continuing many of the traditions of the BRA but with a professional and revamped style. Membership has increased dramatically since this time, now standing at 2000, and the BNA has increasingly taken a leading role in major events, such as hosting the Second Forum of European Neuroscience in Brighton in June, 2000. The BNA is the largest body representing all aspects of neuroscience from ion channels to whole animal behaviour. The Aims and Objectives of the Association are as follows: 1. To promote on a multidisciplinary basis the study of the development structure and function of the nervous system in health and disease. 2. To promote the dissemination of information to all those interested in the neurosciences and related disciplines by means of lectures, discussions, meetings and reports from time to time obtained from such researchers. 3. To advise as far as possible on issues in neurosciences related to health and disease. 4. To endeavour to increase public awareness and understanding of neuroscience research in health and disease. 5. To assist in the training of neuroscientists and other professionals engaged in neuroscience teaching and research. The BNA achieves these aims as follows: 1. By hosting a national meeting biennially, by publishing the proceedings of that meeting and distributing them to the scientific community. 2. By organising a number of focussed ''One Day symposia'' during the year, contributing to training courses for young neuroscientists and organising public lectures and events . 3. By regularly distributing information by the BNA Newsletter or by the BNA News E-mail Alert facility that can inform members about other relevant events, publications and topical issues. 4. By encouraging attendance at its own national meeting and those to which it is affiliated by awarding bursaries to students and young postdoctoral workers, and facilitating participation in the Society for Neuroscience annual meeting by offering sponsored abstract forms. 5. By awarding graduate and undergraduate prizes, and special awards to senior neuroscientists and to lay people who have contributed significantly through their own charitable work to the success of our discipline. 6. By constantly negotiating special discount prices of relevant books and journals, and by offering free online access to the European Journal of Neuroscience.The BNA is the fastest growing learned society, now boasting more than 2000 members, a rise of more than 40% since its relaunch as the BNA in 1997 from the former Brain Research Association. In addition to discounted journals and books and other occasional ''special offers'', the benefits of membership now include the following: 1. Reduced registration fees (up to 50%) to the National Meeting, and FREE admission to many events throughout the year including ''One Day Symposia'' and The Christmas Symposium. 2. Regular mailing of BNA Bulletin and other relevant items. 3. Regular BNA and FENs Email Alert service. 4. Student prizes, and bursaries for attendance at BNA, FENS and IBRO meetings. 5. Free on-line access to European Journal of Neuroscience. 6. Concessionary (SFN membership rate) registration fees and sponsored abstract forms for Society for Neuroscience annual meeting. 7. Free advertising in the BNA Bulletin and on the BNA Website. 8. Free (automatic) membership of the Federation of European Neuroscience Societies (FENS), the International Brain Research Organisation (IBRO) and the Biosciences Federation (BSF). educational resource; jobs.

Proper citation: British Neuroscience Association (RRID:SCR_007402) Copy   

•   Source: SciCrunch Registry

http://www.autism-society.org/

ASA, the nations leading grassroots autism organization, exists to improve the lives of all affected by autism. We do this by increasing public awareness about the day-to-day issues faced by people on the spectrum, advocating for appropriate services for individuals across the lifespan, and providing the latest information regarding treatment, education, research and advocacy. :Founded in 1965 by Dr. Bernard Rimland, Dr. Ruth Sullivan and many other parents of children with autism, ASA is the leading source of trusted and reliable information about autism. Through its strong chapter network, ASA has spearheaded numerous pieces of state and local legislation, including the 2006 Combating Autism Act, the first federal autism-specific law. ASAs website is one of the most visited websites on autism in the world and its quarterly journal, Autism Advocate, has a broad national readership. ASA also hosts the most comprehensive national conference on autism, attended by 2000 people each year. Our information and referral team, our program staff, and our strong chapter presence serve thousands of families each year who are searching for help in their journey with autism. :ASAs national office is headquartered in Bethesda, Maryland. ASA is a member and chapter organization whos national Board of Directors is composed of democratically elected members and appointed members. We are proud to be one of the few organizations to have members with autism serving as active board directors. ASAs Panel of Professional Advisors sets the standards for our Options Policy that governs our practices, and we are proud to count the top professional experts in autism on our PPA. ASAs Panel of People on the Spectrum of Autism Advisors is a first-of-its-kind advisory panel comprised solely of individuals with autism, who help ASA staff create programs and services that will advocate for the rights of all people with autism to live fulfilling, interdependent lives. :Each year, people with autism, families and professionals volunteer thousands of hours to help ASA achieve its mission of serving all those affected by autism. To each and every one of you, thank you :

Proper citation: Autism Society of America (RRID:SCR_007401) Copy   

•   Source: SciCrunch Registry