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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A privately held spinal company that is driving significant technological advancements across a complete suite of spinal products. Founded in 2003, Globus'' single-minded focus on advancing spinal surgery has made it the fastest growing company in the history of orthopedics. Globus is driven to utilize superior engineering and technology to achieve pain free, active lives for all patients with spinal disorders. The ultimate goal at Globus is to deliver innovation by utilizing superior engineering and technology to help improve patients'' lives. This clinical inspiration is central to every endeavor we undertake. We have developed a Spine Innovation Engine to focus our efforts on delivering industry leading solutions to surgeons and their patients. Our Spine Innovation Engine has developed a portfolio that includes a comprehensive line of technologically-advanced spine products. To date we have released over 50 major products and have over 30 more in various stages of development. Clinical Studies are the foundation for advancing innovative spine care and Globus is committed to a robust investment into prospective and retrospective clinical trials to evaluate the safety and efficacy of our products. Globus is currently conducting several FDA-approved Investigational Device Exemption (IDE) clinical studies.
Proper citation: Globus Medical, Inc. (RRID:SCR_004836) Copy
Public research university located in Freiburg im Breisgau, Baden-Württemberg, Germany.
Proper citation: University of Freiburg; Baden-Wurttemberg; Germany (RRID:SCR_004825) Copy
http://compbio.cs.sfu.ca/software-variation-hunter
A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies.
Proper citation: VariationHunter (RRID:SCR_004865) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 17, 2021. An Antibody supplier.
Proper citation: Boston Biochem (RRID:SCR_004761) Copy
http://optn.transplant.hrsa.gov/
The only national patient waiting list and an online database system, called UNet, that links all of the professionals involved in the donation and transplantation system for the collection, storage, analysis, and publication of all OPTN data pertaining to the patient waiting list, organ matching, and transplants. The system contains data regarding every organ donation and transplant event occurring in the U.S. since October 1, 1987. UNet is a fail-safe, 24/7, secure Internet-based transplant information database created to enable the nation''''s organ transplant institutions to: * register patients for transplants * match donated organs to waiting patients * manage the time-sensitive, life-critical data of all patients, before and after their transplants Data reports are available by type: National Data, Regional Data, State Data, Center Data, Build Advanced Report, and Annual Report Data. UNet is being used right now by all of the nation''''s organ transplant programs, organ procurement organizations, and histocompatibility (tissue typing) laboratories working cooperatively to efficiently share a limited number of donated organs among thousands of patients.
Proper citation: Organ Procurement and Transplantation Network (RRID:SCR_004883) Copy
UniGe, is one of the largest universities in Italy. It is located in the city of Genoa and regional Metropolitan City of Genoa, on the Italian Riviera in the Liguria region of northwestern Italy. The original university was founded in 1481.
Proper citation: University of Genoa; Genoa; Italy (RRID:SCR_004878) Copy
http://www.nitrc.org/projects/xnat_extras
User software contributions for XNAT - The Extensible Neuroimaging Archive Toolkit, http://www.xnat.org
Proper citation: XNAT Extras (RRID:SCR_004759) Copy
http://www.cbcb.umd.edu/software/phymm/
Software for Phylogenetic Classification of Metagenomic Data with Interpolated Markov Models to taxonomically classify DNA sequences and accurately classify reads as short as 100 bp. PhymmBL, the hybrid classifier included in this distribution which combines analysis from both Phymm and BLAST, produces even higher accuracy.
Proper citation: Phymm and PhymmBL (RRID:SCR_004751) Copy
https://code.google.com/p/destruct/
A software tool for identifying structural variation in tumour genomes from whole genome illumina sequencing.
Proper citation: deStruct (RRID:SCR_004747) Copy
Wikipedia is a free, web-based, collaborative, multilingual encyclopedia project supported by the non-profit Wikimedia Foundation. Its 19 million articles (over 3.6 million in English) have been written collaboratively by volunteers around the world, and almost all of its articles can be edited by anyone with access to the site. As of July 2011, there were editions of Wikipedia in 282 languages. Wikipedia was launched in 2001 by Jimmy Wales and Larry Sanger and has become the largest and most popular general reference work on the Internet, ranking around seventh among all websites on Alexa and having 365 million readers. The name Wikipedia was coined by Larry Sanger and is a combination of wiki (a technology for creating collaborative websites, from the Hawaiian word wiki, meaning quick) and encyclopedia. Wikipedia''s departure from the expert-driven style of encyclopedia building and the large presence of unacademic content has been noted several times. Some have noted the importance of Wikipedia not only as an encyclopedic reference but also as a frequently updated news resource because of how quickly articles about recent events appear. Although the policies of Wikipedia strongly espouse verifiability and a neutral point of view, critics of Wikipedia accuse it of systemic bias and inconsistencies (including undue weight given to popular culture), and allege that it favors consensus over credentials in its editorial processes. Its reliability and accuracy are also targeted. A 2005 investigation in Nature showed that the science articles they compared came close to the level of accuracy of Encyclopedia Britannica and had a similar rate of serious errors.
Proper citation: Wikipedia (RRID:SCR_004897) Copy
http://wiki.iop.kcl.ac.uk/default.aspx/Neurodegeneration/Neurodegeneration%20Research%20Wiki.html
A wiki which provides information on neurodegenerative diseases to caregivers, students, and researchers.
Proper citation: Neurodegeneration Research Wiki (RRID:SCR_005015) Copy
Public research university in Iowa City, Iowa. Founded in 1847, it is the oldest and the second-largest university in the state.
Proper citation: University of Iowa; Iowa; USA (RRID:SCR_005011) Copy
http://wellness.wikispaces.com/
Wellness Wiki is offered to help clarify the complex problems plaguing the U.S. healthcare system and develop sustainable ways to improve the health and well-being of all people. This virtual encyclopedia of the healthcare crisis and potential remedies welcomes your comments! The Wellness Wiki Book (Understanding & Curing American Healthcare: A Wise Way to Better Outcomes and Lower Costs) is available for purchase as a softcover book or pdf download. Table of contents: *Introduction & Executive Summary *Defining the Problem *Examining Three Proposed Solutions *Introducing a New Solution - Overview and Benefits, Wellness-Plus Solution Tactics, Barriers and Drivers to Implementing the Wellness-Plus Solution *Conclusion & Epilogue *Appendix *Wellness Model Technology Blueprint
Proper citation: Wellness Wiki (RRID:SCR_004957) Copy
http://pythia.sourceforge.net/
Pythia is an open source thermodynamically oriented primer design python module. Pythia can be used in two ways. 1. Executable binaries only: under windows with cygwin and python 2.5 (built with mingw, that comes with the cygwin release). These executables allow the user to index DNA files for primer specificity search, design one primer pair per region, and tile regions with PCR amplicons. 2. A python module: under windows with cygwin, python2.5, numpy, swig, and mingw, or under linux with python2.4 or later, numpy, and swig (everything but numpy should be pre-installed on a normal linux system). The module gets you everything that the binaries get you, in a more pythonic framework. This package also includes modules for computing DNA binding and folding energies using the partition function approach with publicly available thermodynamic data. Usage documentation is in the downloads.
Proper citation: Pythia (RRID:SCR_004952) Copy
http://bioinformatics.rutgers.edu/Software/SLiQ/
Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph.
Proper citation: SLIQ (RRID:SCR_005003) Copy
http://cortexassembler.sourceforge.net/index_cortex_var.html
A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM
Proper citation: cortex var (RRID:SCR_005081) Copy
http://www.appliedbiosystems.com/absite/us/en/home.html
An Antibody supplier
Proper citation: Applied Biosystems (RRID:SCR_005039) Copy
http://www.unmc.edu/physiology/Mann/
The Nervous System In Action by Michael D. Mann, Ph.D. is a textbook on nervous system physiology. Available here is the web accessible version of of this textbook. An Adobe Acrobat (PDF) version is also supplied for better printing. You will need Acrobat Reader to see and print it. The textbook consists of the following: Preface (1) Neurophysiology, An Overview (2) Human Behavior (3) 1. Diffusion and Transport (4) 2. Control Systems and Homeostasis (5) 3a. Properties of Excitable Membranes: The Membrane Potential (6) 3b. Properties of Excitable Membranes: The Spike (7) 4a. Receptor Properties: Receptor Potentials and Coding (8) 4b. Sensory Receptors II (9) 5. Somesthesia--Peripheral Mechanisms (0) 6. Somesthesia--Central Mechanisms (a) 7. Vision (b) 8. Audition (c) 9. The Vestibular System (d) 10.Gustatory and Olfactory Senses (e) 11. Muscle Receptors (f) 12. Peripheral Nerves (g) 13. Synapses (h) 14. Muscle Contraction (i) 15. Reflexes (j) 16. Initiation and Control of Movement (k) 17. Activities Involving the Cerebral Hemispheres (l) 18. The Clinical Implications of Neurophysiological Concepts (m) 19. Learning and Memory Appendix: Common abbreviations (n) Glossary (o) Index (p)
Proper citation: The Nervous System in Action (RRID:SCR_004985) Copy
http://www.physics.rutgers.edu/~anirvans/SOPRA/
Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD.
Proper citation: SOPRA (RRID:SCR_005035) Copy
An Antibody supplier
Proper citation: Bioworld Technology (RRID:SCR_005036) Copy
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