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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/galaxyproject/tools-iuc/tree/master/tools/scater
Software tool as Galaxy based training resource for single cell RNA-seq quality control and analyses.
Proper citation: Galaxy scater (RRID:SCR_017394) Copy
http://paintmychromosomes.com/
Software tool as algorithm for identifying population structure using dense sequencing data. Can perform model based Bayesian clustering on large datasets, including full resequencing data.
Proper citation: fineSTRUCTURE (RRID:SCR_018170) Copy
https://github.com/yousra291987/ChiCMaxima
Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling.
Proper citation: ChiCMaxima (RRID:SCR_018178) Copy
https://github.com/esctrionsit/snphub
Web Shiny-based server framework for retrieving, analyzing and visualizing large genomic variations data.
Proper citation: SnpHub (RRID:SCR_018177) Copy
https://github.com/santeripuranen/SpydrPick
Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree.
Proper citation: SpydrPick (RRID:SCR_018176) Copy
https://www.synapse.org/#!Synapse:syn11459638
Dockerized environment for winning algorithm in 2017 Multiple Myeloma DREAM Challenge, Sub-Challenge 3.
Proper citation: Multiple Myeloma survival predictor (RRID:SCR_017651) Copy
https://github.com/tanghaibao/mcscan
Software package to simultaneously scan multiple genomes to identify homologous chromosomal regions and subsequently align these regions using genes as anchors.Used to identify conserved gene arrays both within same genome and across different genomes. Command line program to wrap dagchainer and combine pairwise results into multi alignments in column format.
Proper citation: MCScan (RRID:SCR_017650) Copy
https://blobtools.readme.io/docs
Software tool as modular command line solution for visualisation, quality control and taxonomic partitioning of genome datasets. Used for interrogation of genome assemblies. Assists in primary partitioning of data, leading to improved assemblies, and screening of final assemblies for potential contaminants.
Proper citation: Blobtools (RRID:SCR_017618) Copy
https://github.com/philres/ngmlr
Software tool as long read mapper designed to align PacBio or Oxford Nanopore reads to reference genome and optimized for structural variation detection.
Proper citation: Ngmlr (RRID:SCR_017620) Copy
https://github.com/WangHYLab/fcirc
Software Python pipeline for linear and circular RNAs of known fusions exploration. Pipeline for exploring linear transcripts and circRNAs of known fusions based on RNA-Seq data. Known fusion genes are from multiple databases like COSMIC, ChimerDB, TicDB, FARE-CAFE and FusionCancer or user-added gene-pairs.
Proper citation: Fcirc (RRID:SCR_018090) Copy
http://www.prc.boun.edu.tr/appserv/prc/hingeprot/index.html
Web server for predicting rigid protein parts and flexible hinge regions connecting them in native topology of protein chains by employing elastic network (EN) models. Automated prediction of hinges in protein structures.
Proper citation: HingeProt (RRID:SCR_018136) Copy
https://github.com/ctlab/GADMA
Software tool to implement methods for automatic inferring joint demographic history of multiple populations from genetic data. Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data.
Proper citation: GADMA (RRID:SCR_017680) Copy
https://crispy.secondarymetabolites.org
Web tool to design sgRNAs for CRISPR applications. Web tool based on CRISPy to design sgRNAs for any user-provided microbial genome. Implemented as standalone web application for Cas9 target prediction.
Proper citation: CRISPy-web (RRID:SCR_017970) Copy
https://github.com/slimsuite/pafscaff
Software as Pairwise mApping Format reference based Scaffold anchoring and super scaffolding tool. Dsigned for mapping genome assembly scaffolds to closely related chromosome level reference genome assembly.
Proper citation: PAFScaff (RRID:SCR_017976) Copy
http://bit.do/canidmeth-github
Software tool for visualisation and quantification of DNA methylation at candidate features.
Proper citation: CandiMeth (RRID:SCR_017974) Copy
https://github.com/AndreMacedo88/VEnCode
Software tool to perform intersectional genetics-related operations to find VEnCodes using databases provided by FANTOM5 consortium, namely CAGE enhancer and transcription start site (TSS) databases.
Proper citation: VEnCode (RRID:SCR_018024) Copy
https://github.com/cramerlab/warp
Software tool that automates all preprocessing steps of cryo-EM data acquisition and enables real-time evaluation. Corrects micrographs for global and local motion, estimates local defocus and monitors key parameters for each recorded micrograph or tomographic tilt series in real time. Software includes deep-learning-based models for accurate particle picking and image denoising.
Proper citation: Warp (RRID:SCR_018071) Copy
Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model.
Proper citation: RaptorX (RRID:SCR_018118) Copy
Webserver to process, analyse and visualise CLIP-Seq data. Software tools to process and visualise RNA protein interactions. CLIP-Seq data analysis in Galaxy. Galaxy CLIP-Explorer can process large CLIP-Seq data of eCLIP, iCLIP, and with simple changes to iCLIP workflows also FLASH, and uvCLAP.
Proper citation: CLIP-Explorer (RRID:SCR_018128) Copy
https://huygens.science.uva.nl/PlotTwist/
Web application for plotting and annotating continuous data. Open source web app for plotting and annotating time series data. Used to inspect data and generate publication quality visualizations. Available options for plotting include lineplot, small multiples and heatmap, summary statistics and inferential statistics.
Proper citation: PlotTwist (RRID:SCR_018331) Copy
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