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http://cmac.concordia.ca/

Services include advise on microscope to use for research project, image acquisition, optimization image analysis and sample preparation, free of charge access to 500GB per laboratory on CMCI server in order to store data for project. Facility houses four wide-field, near-field (TIRF), three confocal (swept-field and laser-scanning) microscopes and laser capture microdissection system.

Proper citation: Concordia University Center for Microscopy and Cellular Imaging Core Facility (RRID:SCR_017804) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioinformatics/

Core to facilitate, amplify, and accelerate biological research and discovery through application of bioinformatics. Provides bioinformatic analysis services for Next Generation Sequencing (NGS) data.

Proper citation: Purdue University Bioinformatics Core Facility (RRID:SCR_017896) Copy   

•   Source: SciCrunch Registry

https://ki-sbc.mit.edu/dsmi

Core provides central hub to help leverage bioinformatics and data science methods in research projects. Services include Transcriptomics: bulk RNA-Seq, single-cell RNA-Seq, and spatial RNA-Seq; Genomics: SNP, structural variants (SV), and copy number variation (CNV) analyses; Regulatory genomics: ChIP-Seq, ATAC-Seq, CUT&RUN, and Hi-C; Functional genomics: CRISPR-based loss-of-function screens;Image and metadata analysis: AI/ML-based approaches including knowledge graphs. Offers training, education, collaboration, consultation,custom guidance on study design and analysis approaches. Provides classroom and custom training sessions on computational, data science, bioinformatics topics, tailored workshops for requested specialized topics. Offers technical infrastructure and support, computing resource optimization and facilitation, bioinformatics software deployment (conda environments and Docker containers), version control and reproducible science (Git repositories), data management support and submission to public repositories.

Proper citation: Koch Institute at MIT Data Science and Multimodal Integration Core Facility (RRID:SCR_017894) Copy   

•   Source: SciCrunch Registry

http://ssom.luc.edu/genomics/

Core provides next-generation sequencing capabilities using Illumina MiSeq. Helps with experimental design, quality control analysis, library preparation, and data analysis. MiSeq desktop sequencer allows to access applications such as targeted gene sequencing, metagenomics, small genome sequencing, targeted gene expression, amplicon sequencing, and HLA typing.MiSeq is capable of delivering up to 15 Gb of output with 25 million sequencing reads and 2x300 basepair read lengths.

Proper citation: Loyola University Genomics Core Facility (RRID:SCR_017857) Copy   

•   Source: SciCrunch Registry

http://nic.ucsf.edu/

Core provides light microscopy instrumentation, microscopy training and education and can provide assistance with experiment design, data acquisition, and image analysis. Provides training for users.Services include:Fluorescence imaging (up to 5 colors) Brightfield, phase contrast, and DIC imaging;High speed imaging (over 100 frames per second);Automated imaging, including multiwell plates;Super-resolution imaging (SIM / STORM / PALM);Single molecule imaging;3D confocal imaging;Gigapixel image stitching;Live cell time lapse imaging;Photoactivation and photobleaching;Light sheet imaging of cleared tissues.

Proper citation: University of California at San Francisco, Nikon Imaging Center Core Facility (RRID:SCR_017862) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/csb/mx/

Core provides support and infrastructure necessary to initiate and successfully complete structural biology or structural chemistry project. Offers services in Crystallization,X-Ray DiffractionData Collection,Structure Determination and Refinement.

Proper citation: North Carolina University at Chapel Hill School of Medicine Macromolecular X-Ray Crystallography Core Facility (RRID:SCR_017839) Copy   

•   Source: SciCrunch Registry

http://hihg.med.miami.edu/cgt/genotyping

Core provides services in analyzing genetic variation, performing genome-wide association studies, conducting non-human genotyping. Offers flexible platforms from low to high throughput, tailored to research needs. Specializes in Illumina Genotyping Arrays and TaqMan Allelic Discrimination Assays, with fully automated processing using Tecan EVOs and BioMek liquid handlers and Genologics LIMS for reliable data tracking.Applications include: GWAS – Identify genetic variants linked to traits and diseases; PRS Analysis – Assess genetic risk for complex diseases; Pharmacogenomics – Study genetic factors in drug response; Population Genetics – Explore ancestry and genetic diversity; CNV Analysis – Detect large-scale genomic variations; Methylation Analysis.

Proper citation: University of Miami Hussman Institute for Human Genomics Genotyping Core Facility (RRID:SCR_017820) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/flowcytometry/index.html

Flow cytometry core to measure phenotypic, biochemical and molecular characteristics of individual cells or particles suspended in fluid stream.Flow Cytometry Core on Jupiter, Florida campus of Scripps Research provides services including Cell Sorting, Analytical Cytometry,Data Analysis,Microdissection and Imaging. Hematology services including:Cell Sorting on ARIA: violet, blue, green and red lasers and on FUSION: violet, blue, green and red lasers; Cell Analysis on LSR2: ultra-violet, violet, blue, green and red lasers, GALLIOS: violet, blue, green and red lasers,CANTO: violet, blue and red lasers;Laser Microdissection and Fluorescence Imaging using LEICA LMD 7000;Hematology using HEMAVET 950FS.

Proper citation: Scripps Research Institute - Florida Flow Cytometry Core Facility (RRID:SCR_017830) Copy   

•   Source: SciCrunch Registry

https://biophysics.fsu.edu/facilities/x-ray-crystallography-facility

Shared macromolecular x-ray crystallography facility provides instruments and expertise for screening, optimizing, imaging, growing, and storing crystals of biological macromolecules. The X-Ray Facility coordinates single crystal x-ray diffraction data collection at third generation synchrotron x-ray source using FSU's membership at the National Synchrotron Light Source II at Brookhaven National Lab, Upton, NY. XRF also offers custom buffer preparation, optimization, and crystal set-up using multi-well format crystallization blocks and plates.XRF has ARI Crystal Gryphon robot, Formulatrix Rock Imager, Formulator 16, Rock Maker software, RUMED incubator, Cryo storage and shipping dewars, Leica S8 AP0 Zoom microscope and other amenities.

Proper citation: Florida State University X-Ray Crystallography Core Facility (RRID:SCR_017922) Copy   

•   Source: SciCrunch Registry

http://www.kumc.edu/school-of-medicine/hoglund-brain-imaging-center/facilities-and-resources.html

Core provides imaging capabilities, including magnetic resonance imaging, magnetoencephalolgraphy, electroencephalography, magnetocardiography, and ultrasound,expertise in cognitive neuroscience, neurobiology, biomedical physics, and computing, together with support team of technologists, nurses, research associates, and research assistants. Through strong collaborations, these individuals assist with study design, collection of data, analysis, and interpretation of results. HBIC supports investigators with new technique development, feasibility studies, pilot funding, preparing grant applications and manuscripts, and compliance. Carries out investigator-initiated research and research/clinical trials sponsored by public and private agencies. Offers education and training.

Proper citation: Kansas University Medical Center Hoglund Brain Imaging Center Core Facility (RRID:SCR_017920) Copy   

•   Source: SciCrunch Registry

https://www.biotech.iastate.edu/metabolomics/

Core facility that conducts fee for service mass spectrometry-based non-targeted and targeted metabolomic studies. The facility serves and partners with both on- and off-campus clients.

Proper citation: Iowa State University W.M. Keck Metabolomics Research Laboratory Core Facility (RRID:SCR_017911) Copy   

•   Source: SciCrunch Registry

https://www.igb.illinois.edu/corefacilities

Core for biological microscopy and image analysis. Offers high-end equipment,user training,ongoing support, including experiment design and data interpretation,twenty-four hour access Services,3D Printing, Transfer Files, Image Analysis,Histology,Instrument Training.

Proper citation: University of Illinois at Urbana-Champaign Core Facilities at IGB (RRID:SCR_017938) Copy   

•   Source: SciCrunch Registry

https://www.preventivemedicine.northwestern.edu/divisions/biostatistics/

Core where division members engage in statistical methods development and application, research design and statistical computing for health science research. Faculty interests encompass Bayesian methods, bioinformatics, causal inference, computational biology, clinical trials, diagnostic testing, longitudinal modeling, missing data modeling, observational data methods, semi-parametric models, spatial modeling, statistical genetics and survival analysis.

Proper citation: Northwestern University Biostatistics Collaborative Center (RRID:SCR_017943) Copy   

•   Source: SciCrunch Registry

https://education.musc.edu/colleges/medicine/departments/pharmacology/redox-center/cores/bioenergetics-profiling-core

Core provides several technologies that enable researchers to quantify fluxes of these metabolic reactions in cells, tissues, organoids and small animal models such as zebrafish embryos and nematodes.Technologies include high resolution respirometry using XF technology from Seahorse Biosciences/Agilent. Instrumentation utilizes 96-well microplates to provide sufficient sample numbers to provide flux profiles of glycolysis, mitochondrial respiration, fatty acid oxidation, glutamine utilization and other related metabolic processes. Rapid, high-throughput imaging optimized to XF plate architecture provides normalization of cell/tissue numbers, health, and other.Provides training, data analyses support and aid in experimental design.

Proper citation: South Carolina Medical University Bioenergetics Profiling Core Facility (RRID:SCR_017953) Copy   

•   Source: SciCrunch Registry

https://knightadrc.wustl.edu/professionals-clinicians/request-center-resources/

Provides on request resources including Data: clinical and cognitive measures as well as MRI and amyloid imaging scans; Tissue: frozen brain tissue, paraffin brain sections, antemortem CSF, DNA, fibroblast, dermal fibroblasts, plasma (fasting and non-fasting) and iPSC; Participants: eligible participants may be invited to enroll in research of other investigators after appropriate review. Researchers can use the request portal to review Center guidelines and policies; view available data and tissue; access data tables and codebooks; and submit request for resources.

Proper citation: Washington University School of Medicine Knight ADRC Request Center Resources Core Facility (RRID:SCR_025254) Copy   

•   Source: SciCrunch Registry

https://dsigdb.tanlab.org/DSigDBv1.0/

Online database provides collection of gene sets based on quantitative inhibition and/or drug-induced gene expression changes data of drugs and compounds. Allows users to search, view and download drugs/compounds and gene sets.

Proper citation: DSigDB (RRID:SCR_026202) Copy   

•   Source: SciCrunch Registry

https://marmotgraph.org

Knowledge graph system developed for managing and organizing rich metadata objects, initially for the Human Brain Project (HBP) and now extended to be a more generic, domain-agnostic solution. It is associated with CSCS (Swiss National Supercomputing Centre) and aims to provide a comprehensive toolset and API for working with knowledge graphs.

Proper citation: MarmotGraph (RRID:SCR_027452) Copy   

•   Source: SciCrunch Registry

https://www.bwhneurosciences.org/neurotechnology-studio/

Offers advanced instrumentation and expert support to advance understanding of brain function and brain disease by providing researchers with access to cutting-edge technologies. Provides access to advanced instrumentation for optical microscopy, genomics, metabolic imaging and other technologies, as well as image analysis software. Provides expert support and training, data quality and interpretation.

Proper citation: Brigham and Women’s Hospital NeuroTechnology Studio Core Facility (RRID:SCR_027687) Copy   

•   Source: SciCrunch Registry

http://www.concepthub.org/wiki/Main_Page

THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 18, 2016. A database built up with software and services that maintains multiple versions of terminologies, map sets, and values sets concurrently. HDD Access has superseded Concept Hub.

Proper citation: Concept Hub (RRID:SCR_013586) Copy   

•   Source: SciCrunch Registry

https://www.digitalpsych.org/mindlamp1.html

Core collects data to capture and consider the real-time lived experiences of patients. Uses open-source digital platform and mobile app for neuropsychiatric research and clinical care, to monitor, support, and improve brain health by collecting real-time data (like location, activity, heart rate via sensors), conducting digital assessments (surveys, cognitive tests), and delivering interventions (meditation, journaling, psychoeducation) to patients and clinicians. It helps study behavioral patterns, track symptoms, and personalize mental health treatment through features organized around Learn, Assess, Manage, and Prevent.

Proper citation: BIDMC Division of Digital Psychiatry LAMP platform Core Facility (RRID:SCR_027767) Copy   

•   Source: SciCrunch Registry