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http://www.scienceexchange.com/facilities/histopathology-core

Both animal model and clinical research require the production of high quality tissue samples for morphological and molecular analyses. The NYU Histopathology Core, one component of the Experimental Pathology Shared Resources provides?_services, instrumentation and training to facilitate the generation of these critical materials. Services offered by the Histopathology Core include: tissue preparation, processing, embedding, sectioning, histochemical staining, digital whole slide scanning, and laser capture microdissection of both animal and fixed human tissues. The Histopathology Core also makes available several instruments for investigator use on a self-serve basis. This option is valuable for researchers who wish to direct certain stages of specimen preparation and is more cost-effective in some cases. Available instrumentation includes a state-of the-art Laser Dissection Microscope, a microtome, a cryostat and a microscope fitted with a digital camera. Training is provided by Core staff. The components of pricing for each service include the cost of consumables, the cost for technician time for each service, and a small percentage of any associated service contracts. As with many of our services, the incremental cost of each procedure is affected by overall volume; as volume increases, we pass the resulting savings on to users in the form of reduced prices.

Proper citation: NYU Histopathology Core (RRID:SCR_012409) Copy   

•   Source: SciCrunch Registry

https://www.moffitt.org/research-science/shared-resources/small-animal-imaging-lab/

Core provides advanced and affordable multi-modality imaging services including consultation, imaging and image analysis for both basic and translational research. Offers instrumentation including 7T MRI, multimodal PET/SPECT/CT, ultrasound and optical modalities. Used to evaluate tumor development, progression, metastasis and therapy response in rodent models of cancer including development of imaging biomarkers, contrast agents and tumor targeting agents, evaluating tumor metabolism and microenvironment, and high-resolution anatomical imaging of human specimens.

Proper citation: Moffitt Cancer Center Small Animal Imaging Laboratory Core Facility (RRID:SCR_012401) Copy   

•   Source: SciCrunch Registry

https://www.umc.edu/Research/Core-Facilities/Departmental%20Core%20Facilities/Animal-Behavior-Core.html

Provides tools and assistance to identify and monitor behavior in rodents. Supports basic and translational research by providing assistance with project development, technical assistance to identify and monitor behavior in rats and mice, training in techniques for analysis of animal behaviors, assisting with interpretation and presentation of data and results relating to animal behaviors.

Proper citation: University of Mississippi Medical Center Animal Behavior Core Facility (RRID:SCR_012494) Copy   

•   Source: SciCrunch Registry

https://tacc.utexas.edu/

Texas Advanced Computing Center (TACC) at The University of Texas at Austin is one of the leading centers of computational excellence in the United States. Located on the J.J. Pickle Research Campus, the center''''s mission is to enable discoveries that advance science and society through the application of advanced computing technologies. To fulfill this mission, TACC identifies, evaluates, deploys, and supports powerful computing, visualization, and storage systems and software. TACC staff help researchers and educators use these technologies effectively, and conduct research and development to make these technologies more powerful, more reliable, and easier to use. TACC staff also help encourage, educate, and train the next generation of researchers, empowering them to make discoveries that change the world.

Proper citation: Texas Advanced Computing Center (RRID:SCR_012530) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/neurotransgenic-laboratory-duke

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Neurotransgenic Laboratory (NTL) at Duke University conducts technology development research and provides services, tools, and training towards the genetic analysis of the nervous system. Such tools include viruses for the precise stereotactical application of transgenes, plasmids and BACs for the generation of transgenic animals, genetically modified embryonic and induced pluripotent stem cells for differentiation and transplantation studies as well as for the generation of genetically modified animals.

Proper citation: Duke Neurotransgenic Laboratory (RRID:SCR_012496) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/rbc/

One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.

Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/baker-mountain-research-corporation

We are a not-for-profit scientific research corporation founded in 2010. The mission of the Baker Mountain Research Corporation has three complementary aspects: to advance scientific knowledge, to develop science-based solutions to local and global challenges, and to foster scientific education. A particular challenge we seek to address is the lack of scientific career and educational opportunities in our region. We work to build an interdisciplinary community that facilitates synthetic and analytic exploration, mentorship, sharing of experiences and which provides fair financial support.

Proper citation: Baker Mountain Research Corporation (RRID:SCR_012531) Copy   

•   Source: SciCrunch Registry

https://ophthalmology.pitt.edu/research/core-research-facilities/tissue-culture-histology-module

Core offers Tissue Culture Services including Basic Cell Culture, Specialized Culture Services, Virus Services; Histology Services including Paraffin Histology, Frozen Histology, Monolayers,Personnel Training and more.

Proper citation: University of Pittsburgh Department of Ophthalmology Tissue Culture and Histology Module Core Facility (RRID:SCR_012412) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/agcenter-biotechnology-laboratory-lsu

The LSU AgCenter Biotechnology Laboratory (ABL) is a core facility that provides basic and applied research expertise to support researchers in the LSU system as well as those in other academic institutions and industry. The ABL was formed in 1998 to provide support to faculty in performing biomolecular research. In 2010, the ABL was merged with the Protein Facility in LSU''''s College of Basic Sciences. Today, the ABL consists of three units: the Protein Facility, the Plant Transformation Facility and the Animal Cell Culture Facility.

Proper citation: LSU AgCenter Biotechnology Laboratory (RRID:SCR_012536) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/children-s-hospital-boston-intellectual-and-developmental-disabilities-research-center-molecular-genetics-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8,2024. An Core facility

Proper citation: Childrens Hospital Boston Intellectual And Developmental Disabilities Research Center - Molecular Genetics Core (RRID:SCR_012414) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html

MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.

Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cri-flow-cytometry-shared-facility

The UT Southwestern CRI Flow Cytometry Shared Facility is a GLP certified lab.

Proper citation: UT Southwestern CRI Flow Cytometry Shared Facility (RRID:SCR_012422) Copy   

•   Source: SciCrunch Registry

https://bcmb.franklin.uga.edu/bff

BFF consists of Fermentation Research Facility, Protein Purification Facility, Monoclonal Antibody Facility and Cell Culture Facility. Provides services covering wide range of biomanufacturing areas, protein expression, purification and antibody discovery.Provides equipment and expertise in biotechnological applications to academic and industry clients.

Proper citation: University of Georgia Bioexpression and Fermentation Core Facility (RRID:SCR_012421) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gvk-bio-chemistry-group

GVK Biosciences has expertise in small molecule synthesis from milligrams to kilo gram scale. Our Chemistry team serves diverse customer requirements from custom synthesis to scale-up through discovery chemistry. Customers can avail these services on a stand-alone or integrated services basis. Advantages of working with GVK Biosciences include: * No Conflict model: GVK BIO has no internal programs. * The IP /Confidentiality of Customers is well protected * Proven ability to Scale from mg to kg level at one location * On-line project tracking * E-Note book reporting (Optional) * Chemistry complemented by expert services in Biology and Computational Chemistry * The largest SAR manually curated database with 4 million compounds available * Multiple research sites across India * Comprehensive technical team with relevant Pharmaceutical, Biopharmaceutical, and Academic experiences. Highly qualified and experienced team * State of the art Analytical instrumentation with experienced analytical research scientists

Proper citation: GVK BIO Chemistry Group (RRID:SCR_012542) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/machine-shop-umass

The UMMS Machine Shop is a support service dedicated to assisting research in a technical/mechanical manner. Although all types of basic laboratory apparatus are manufactured and repaired on a regular basis, we specialize in design and fabrication of equipment that is not commercially available. No job too big or too small, too simple or too complex. Our staff is experienced and knowledgeable in working with all plastics and composites, all metals and alloys. We have over 35 years combined of experience in biomedical design and machining experience and are always available to discuss projects either at the shop or at your location. The Machine Shop is located at the Shrewsbury Campus. Pick-up and delivery of jobs can be arranged at your convenience.

Proper citation: UMass Medical School Machine Shop (RRID:SCR_012633) Copy   

•   Source: SciCrunch Registry

https://www.crr.columbia.edu/raraf

RARAF is dedicated to providing user-friendly radiation sources and bio-labs for research in biology, radiation biology, and radiation physics.

Proper citation: Columbia University Radiological Research Accelerator Core Facility (RRID:SCR_012639) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/transgenic-mouse-shared-resource-columbia

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Core facility that specializes in the generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for biomedical research. Our services include: Production of transgenic mice by pronuclear DNA microinjection and embryo transfer. Production of chimeric mice by blastocyst injection of genetically modified ES cells and embryo transfer, which is part of the procedure of producing knockout or knockin mice. Gene targeting, which involves the electroporation of a targeting vector into pluripotent mouse embryonic stem (ES) cells and the selection of gene-targeted clones. Education of investigators and advice on vector and experimental design for experiments using transgenic and knockout mice. Bioimaging: The Animal Imaging Service provides investigators the opportunity for non-invasive detection, localization, and longitudinal monitoring of primary and metastatic cancer cells in vivo, in allograft, zenograft, transgenic and knock-out mouse models. The IVIS Spectrum (Caliper Life Sciences, Hopkinton MA) uses optical imaging technology to detect bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. DNA samples and ES cell lines are injected in the order in which the signed service request forms are received. Currently, the average time from receipt of the service request to injection is approximately 2 weeks. For ES Cell electroporation and expansion, success in gene targeting cannot be guaranteed due to inherent variability in the frequency of targeting different loci, and the possibility of mistakes or mutations in the targeting vector.

Proper citation: Columbia Transgenic Mouse Shared Resource (RRID:SCR_012640) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-core-laboratory-upenn

The Electron Microscopy Resource Laboratory (EMRL ) at Penn is a research facility dedicated to ultrastructure analysis of biological samples by electron microscopy (EM). We offer high quality EM imaging services at low cost. With a team of experienced professional staff and state-of-the-art sample preparation and imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services.

Proper citation: Penn Electron Microscopy Core Laboratory (RRID:SCR_012642) Copy   

•   Source: SciCrunch Registry

https://pcrlab.vetmed.ucdavis.edu/

Real-time PCR Research and Diagnostics Core Facility accepts research projects from both academic and private sector. The Core Facility can accommodate projects involving laser microdissection, RNA and DNA extractions through semi-automated nucleic acid extractions systems, cDNA synthesis and complete Real-time PCR analysis using a laser 7900 HTA FAST platform.

Proper citation: University of California at Davis Real Time PCR Research and Diagnostics Core Facility (RRID:SCR_012641) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cell-and-cell-products-fermentation-facility

Since its inception in 1951, the fermentation facility''s goal has been to provide affordable fermentation services to a highly diverse client base. Completely renovated in 2011 the fermentation facility, which meets BL2-LS containment requirements, is comprised of four contiguous operation units: -Material Preparation Laboratory -Fermentation In-Process -Computer Control -Product Recovery Room Bio-reactor working capacities range from 10 to 800 liters. All systems are computer controlled with algorithm-based cascade-capable PID programming. In the recovery room, downstream processing includes: -Centrifugation -Filtration -Micro and Ultra-filtration -Cell Disruption With the advantage of having the world''s pharmaceutical industry in its backyard, a productive climate of industrial liaison has been the historical legacy of the facility. Many former facility students and graduates hold positions within the industry. www.waksman.rutgers.edu/fermentation/home

Proper citation: Rutgers Cell and Cell Products Fermentation Facility (RRID:SCR_012729) Copy   

•   Source: SciCrunch Registry