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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) software application, software resource, data processing software COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-07-26 09:04:39 164
SeqExpress
 
Resource Report
Resource Website
SeqExpress (RRID:SCR_007075) software application, software resource, data processing software A comprehensive analysis and visualization software package for gene expression experiments that provides: a number of clustering and analysis techniques; integrated gene expression and analysis result visualizations, integration with the Gene Expression Omnibus; and an optional data sharing architecture. GO is used to assign functional enrichment scores to clusters, using a combination of specially developed techniques and general statistical methods. These results can be explored using the in built ontology browsing tool or through the generated web pages. SeqExpress also supports numerous data transformation, projection, visualization, file export/import, searching, integration (with R), and clustering options. gene, gene expression, function, analysis, visualization, statistical analysis, windows, c#, gene function, chromosome location, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Gene Expression Omnibus
PMID:14988116 Free nlx_149285, biotools:seqexpress https://bio.tools/seqexpress SCR_007075 2026-07-26 09:04:28 0
epigenomix
 
Resource Report
Resource Website
1+ mentions
epigenomix (RRID:SCR_006407) epigenomix software application, software resource, data processing software Software package for the integrative analysis of microarray based gene expression and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types. epigenetic, gene expression, microarray, histone modification, chip-seq, classification, differential expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24403540 GNU Lesser General Public License, v3 biotools:epigenomix, OMICS_02205 https://bio.tools/epigenomix SCR_006407 epigenomix - Epigenetic and gene expression data normalization and integration with mixture models 2026-07-26 09:04:16 2
SOAPaligner/soap2
 
Resource Report
Resource Website
100+ mentions
SOAPaligner/soap2 (RRID:SCR_005503) SOAPaligner, SOAP2 software application, software resource, data processing software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Updated version of SOAP software for short oligonucleotide alignment that features in super fast and accurate alignment for huge amounts of short reads generated by Illumina/Solexa Genome Analyzer., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, alignment, short read, oligonucleotide, single-read, pair-end, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SOAP
PMID:19497933
DOI:10.1093/bioinformatics/btn025
THIS RESOURCE IS NO LONGER IN SERVICE biotools:soap2 https://bio.tools/soap2, https://sources.debian.org/src/soapaligner/ SCR_005503 2026-07-26 09:03:57 322
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) software application, software resource, data processing software Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support ;
Australian Government
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread, https://sources.debian.org/src/subread/ SCR_009803 2026-07-26 09:05:12 1854
GSA-SNP
 
Resource Report
Resource Website
10+ mentions
GSA-SNP (RRID:SCR_013109) GSA-SNP software application, software resource, data processing software A tool for the gene-set (or pathway) analysis of a genome-wide association study result. It accepts a genome-wide list of SNPs and their association P-values. It summarizes the SNP P-values into nearby genes. The gene-by-gene summary results are then further summarized by gene-sets such as Gene Ontology, KEGG pathways, or user-created gene-sets. Various standardization and statistical tests can be performed and the resulting gene-sets that pass a significance level after multiple-testing correction are reported. The tool is written in Java and is available as a standalone version. clinical neuroinformatics, computational neuroscience, imaging genomics, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Soongsil University; Seoul; South Korea
PMID:20501604 GNU General Public License v2 nlx_155765, biotools:gsa-snp https://bio.tools/gsa-snp SCR_013109 2026-07-26 09:05:49 18
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! software application, software resource, data processing software Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore, https://bio.tools/trim_galore, https://sources.debian.org/src/trim-galore/ SCR_011847 TrimGalore 2026-07-26 09:05:32 6255
docker4seq
 
Resource Report
Resource Website
1+ mentions
docker4seq (RRID:SCR_017006) software application, software resource, data processing software Software R package to execute next generation sequencing computing applications, e.g. reads mapping and counting, wrapped in docker containers. next, generation, sequencing, computing, application, read, mapping, count, docker, container, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: University of Turin;Turin;Italy
Free, Available for download, Freely available biotools:docker4seq https://kendomaniac.github.io/docker4seq/index.html, https://bio.tools/docker4seq SCR_017006 2026-07-26 09:06:54 5
ProCon - PROteomics CONversion
 
Resource Report
Resource Website
1+ mentions
ProCon - PROteomics CONversion (RRID:SCR_016363) ProCon software application, software resource, data processing software Java based conversion tool for conversion of data from Proteomics files or a LIMS (Laboratory Information Management System) database into standard formats. Used to support wet-lab scientists in creating proteomics data files ready for upload into the public repositories. data, proteomics, conversion, file, laboratory, information, management, system, database, standard, format, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Ruhr University Bochum; North Rhine-Westphalia; Germany
European Union Projects ProDac ;
European Union Projects ProteomeXchange ;
the German Federal Ministry of Education and Research BMBF
PMID:26182917 Free, Available for download, Freely available biotools:procon https://bio.tools/procon SCR_016363 PROteomics CONversion 2026-07-26 09:06:43 1
ScaffMatch
 
Resource Report
Resource Website
1+ mentions
ScaffMatch (RRID:SCR_017025) software application, software resource, data processing software Software tool as scaffolding algorithm based on maximum weight matching able to produce high quality scaffolds from next generation sequencing data (reads and contigs). Able to handle reads with both short and long insert sizes. scaffolding, algorithm, maximum, weight, matching, next, generation, sequencing, data, read, contig, bio.tools uses: Python Programming Language
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Georgia State University; Georgia; USA
NSF IIS 0916401 PMID:25890305 Free, Available for download, Freely available biotools:scaffmatch, OMICS_08198 http://alan.cs.gsu.edu/NGS/?q=content/scaffmatch, https://bio.tools/scaffmatch SCR_017025 2026-07-26 09:06:54 1
Racon
 
Resource Report
Resource Website
100+ mentions
Racon (RRID:SCR_017642) software application, software resource, data processing software Software tool as de novo genome assembly from long uncorrected reads. Used to correct raw contigs generated by rapid assembly methods which do not include consensus step. Supports data produced by Pacific Biosciences and Oxford Nanopore Technologies. Assembly, de novo, long, uncorrected, read, raw, contig, consensus, step, data, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Croatian Science Foundation ;
Croatian Academy of Sciences and Arts ;
A*STAR ;
Singapore
DOI:10.1101/068122 Free, Available for download, Freely available OMICS_25714, biotools:Racon, BioTools:Racon https://bio.tools/Racon, https://sources.debian.org/src/racon/ SCR_017642 2026-07-26 09:07:03 149
CiLiQuant
 
Resource Report
Resource Website
CiLiQuant (RRID:SCR_019319) software application, software resource, data processing software Software tool to separate junction reads based on their linear or circular origin. Only non ambiguous junction reads are used to compare relative linear and circular transcript abundance. RNA, splicing, circular origin, separate junction reads, circular transcript abundance, linear transcript abundance, compare, bio.tools is listed by: bio.tools
is listed by: Debian
FWO ;
Special Research Fund UGent ;
Stichting Tegen Kanker ;
Kom Op Tegen Kanker (Stand Up To Cancer) ;
European Union's Horizon 2020
Free, Available for download, Freely available biotools:ciliquant https://bio.tools/ciliquant SCR_019319 2026-07-26 09:07:34 0
FlowCal
 
Resource Report
Resource Website
1+ mentions
FlowCal (RRID:SCR_018140) software application, software resource, data processing software Open source software tool for automatically converting flow cytometry data from arbitrary to calibrated units. Can be run using intuitive Microsoft Excel interface, or customizable Python scripts. Software accepts Flow Cytometry Standard (FCS) files as inputs and is compatible with different calibration particles, fluorescent probes, and cell types. Automatically gates data, calculates common statistics, and produces plots. Converting flow cytometry data, arbitrary unit, calibrated unit, data gating, statistic, plot, data, bio.tools is listed by: Debian
is listed by: bio.tools
NSF EFRI 1137266;
NSF MCB 1244135;
Office of Naval Research MURI N000141310074;
Office of Naval Research YIP N000141410487;
NIAID R21 AI115014;
Welch Foundation ;
NSF Graduate Research Fellowship DGE 0940902;
NDSEG Fellowship
PMID:27110723 Free, Available for download, Freely available biotools:flowcal https://bio.tools/flowcal SCR_018140 Python Flow Cytometry Calibration Library 2026-07-26 09:07:12 5
halSynteny
 
Resource Report
Resource Website
1+ mentions
halSynteny (RRID:SCR_018127) software application, software resource, data processing software Software tool as conserved synteny block construction method for multiple whole-genome alignments. Implementation of DAG-based for reconstruction of synteny blocks from genome alignment. Conserved synteny, block construction method, genome alignment, DAG based reconstruction, synteny block, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:halSynteny https://bio.tools/halSynteny SCR_018127 Hierarchical Alignment Format Synteny 2026-07-26 09:07:12 3
PEPPER
 
Resource Report
Resource Website
1+ mentions
PEPPER (RRID:SCR_000431) PEPPER software application, software resource A Cytoscape app designed to identify protein pathways / complexes as densely connected subnetworks from seed lists of proteins derived from pull-down assays (i.e AP-MS...). plugin, protein-protein interaction, network, bio.tools is listed by: OMICtools
is listed by: Cytoscape
is listed by: bio.tools
is listed by: Debian
PMID:25138169 Free, Available for download, Freely available biotools:pepper, OMICS_05485 https://bio.tools/pepper SCR_000431 Protein complex Expansion using Protein-Protein intERaction networks, Protein complex Expansion using Protein-Protein intERactions 2026-07-26 09:02:47 1
GERMLINE
 
Resource Report
Resource Website
100+ mentions
GERMLINE (RRID:SCR_001720) GERMLINE software application, software resource Software application for discovering long shared segments of Identity by Descent (IBD) between pairs of individuals in a large population. It takes as input genotype or haplotype marker data for individuals (as well as an optional known pedigree) and generates a list of all pairwise segmental sharing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, c++, linux, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Columbia University; New York; USA
PMID:18971310 Free, Available for download, Freely available biotools:germline, OMICS_00202, nlx_154080 https://bio.tools/germline http://www1.cs.columbia.edu/~gusev/germline/ SCR_001720 2026-07-26 09:03:05 451
BREAKDANCER
 
Resource Report
Resource Website
100+ mentions
BREAKDANCER (RRID:SCR_001799) BreakDancer software application, software resource A Perl/C++ software package that provides genome-wide detection of structural variants from next generation paired-end sequencing reads. BreakDancerMax predicts five types of structural variants: insertions, deletions, inversions, inter- and intra-chromosomal translocations from next-generation short paired-end sequencing reads using read pairs that are mapped with unexpected separation distances or orientation. (entry from Genetic Analysis Software) gene, genetic, genomic, perl, c++, next generation sequencing, structural variant, insertion, deletion, inversion, inter-chromosomal translocation, intra-chromosomal translocation, chromosomal translocation, indel, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
PMID:19668202 Free, Available for download, Freely available biotools:breakdancer, nlx_154253, OMICS_00307 https://bio.tools/breakdancer SCR_001799 2026-07-26 09:03:04 370
HAPLOPAINTER
 
Resource Report
Resource Website
10+ mentions
HAPLOPAINTER (RRID:SCR_001710) HaploPainter software application, software resource A pedigree drawing program, suitable in processing haplotype outputs from GENEHUNTER, ALLEGRO, MERLIN, and SIMWALK (entry from Genetic Analysis Software) gene, genetic, genomic, perl, pedigree, haplotype, draw, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:15377505 Free, Freely Available nlx_154062, OMICS_00209, biotools:haplopainter https://bio.tools/haplopainter http://haplopainter.sourceforge.net/html/ManualIndex.htm SCR_001710 2026-07-26 09:03:03 45
PEDHUNTER
 
Resource Report
Resource Website
1+ mentions
PEDHUNTER (RRID:SCR_002031) PedHunter software application, software resource Software package that facilitates creation and verification of pedigrees within large genealogies. The pedigrees are produced as files in LINKAGE format ready for linkage analysis and for drawing with a variety of drawing programs, such as PEDDRAW and cranefoot. gene, genetic, genomic, genealogy, pedigree, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: NCBI
PMID:20433770
PMID:9521925
THIS RESOURCE IS NO LONGER IN SERVICE biotools:pedhunter, OMICS_00211, nlx_154518 https://bio.tools/pedhunter SCR_002031 2026-07-26 09:03:08 2
cortex
 
Resource Report
Resource Website
100+ mentions
cortex (RRID:SCR_002467) cortex software application, software resource Software package with functions that will help researchers plan how many subjects per group need to be included in an MRI-based cortical thickness study to ensure a thickness difference is detected. The package requires cortical thickness mapping and co-registration to be carried out using Freesurfer. The power analyses are implemented in the R software package., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. clinical neuroinformatics, mgh/mgz, magnetic resonance, r, surface analysis, thickness, mri, cortical thickness, morphometry, neuroimaging, power analysis, study design, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: bio.tools
is listed by: Debian
has parent organization: Brain Research Institute
PMID:22807270 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155842, biotools:cortex http://brain.org.au/software/cortex/power, http://www.nitrc.org/projects/cortex, https://bio.tools/cortex SCR_002467 Sample Size Estimates for Well-Powered Cross-Sectional Cortical Thickness Studies 2026-07-26 09:03:14 374

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