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Organism Name
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RRID:IMSR_JAX:006022
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Organism Information

URL: https://www.jax.org/strain/006022

Proper Citation: RRID:IMSR_JAX:006022

Description: Mus musculus with name NOD.Cg-Rag1tm1Mom H2-Ab1 Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ from IMSR.

Species: Mus musculus

Synonyms: NOD.Cg-Rag1 H2-Ab1 Tg(CD2-CD4.HLA-DQA1*0301.HLA-DQB1*0302)1Ell/EllJ. NOD.Cg-Rag1 H2-Ab1 Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ

Notes: gene symbol note: CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1; mutant strain|congenic strain: CD4|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell|H2-Ab1|Rag1|CD2|HLA-DQA1|HLA-DQB1

Affected Gene: CD4 molecule|transgene insertion 1; John F Elliott|histocompatibility 2; class II antigen A; beta 1|recombination activating 1|CD2 molecule|major histocompatibility complex; class II; DQ alpha 1|major histocompatibility complex; class II; DQ beta 1

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Ratings and Alerts

No rating or validation information has been found for NOD.Cg-Rag1tm1Mom H2-Ab1 Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.

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Data and Source Information

Source: Integrated Animals

Source Database: JAX Mice and Services