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Organism Name
Organism Information

URL: https://www.infrafrontier.eu/emma/strain-details/?q=6943

Proper Citation: RRID:IMSR_EM:06943

Description: Mus musculus with name STOCK Rag2tm1Fwa B2m Prf1 H2-Ab1 Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl from IMSR.

Species: Mus musculus

Synonyms: STOCK Rag2 B2m Prf1 H2-Ab1 Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl

Notes: gene symbol note: beta-2 microglobulin|transgene insertion 1; Daniel M Altmann|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|perforin 1 (pore forming protein)|histocompatibility 2; class II antigen A; beta 1; mutant strain: B2m|Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|Tg(HLA-A/H2-D/B2M)1Bpe|Rag2|Prf1|H2-Ab1

Affected Gene: beta-2 microglobulin|transgene insertion 1; Daniel M Altmann|transgene insertion 1; Beatrice Perarnau|recombination activating gene 2|perforin 1 (pore forming protein)|histocompatibility 2; class II antigen A; beta 1

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Ratings and Alerts

No rating or validation information has been found for STOCK Rag2tm1Fwa B2m Prf1 H2-Ab1 Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.

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Data and Source Information

Source: Integrated Animals

Source Database: European Mouse Mutant Archive