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Medical College of Wisconsin Comprehensive Rodent Metabolic Phenotyping Core Facility (RRID:SCR_028283)Copy Citation Copied
URL: https://mcw.ilab.agilent.com/service_center/5692/?tab=about
Proper Citation: Medical College of Wisconsin Comprehensive Rodent Metabolic Phenotyping Core Facility (RRID:SCR_028283)
Description: Core provides guided access to novel technologies for complete dissection of energy flux in rodents and other small animals. Our expert staff assist in development, testing, and standardization of metabolic technologies and workflows to leverage both mouse and rat models of interest. Facility offers 16-cage multiplexed metabolic phenotyping system (Promethion, Sable Systems International) that provides detailed mechanistic dissection of resting metabolic rate (RMR), physical activity, and ingestive behaviors of rodents in home style cage designs across the light cycle. CRMPC combines RMR assessments with direct/combined calorimetry (total heat dissipation) to enable assessment of anaerobic forms of energy expenditure (gut microbiome). Additional services include body composition analysis (via NMR), bone content and density analysis (via DEXA), metabolic caging, indirect calorimetry, bioimpedance spectroscopy, thermal imaging. Staff provide guidance for experimental design, execution of studies, statistical analysis of resulting data, and regulatory assistance and compliance.
Synonyms: Comprehensive Rodent Metabolic Phenotyping Core (CRMPC) at the Medical College of Wisconsin
Resource Type: access service resource, core facility, service resource
Keywords: ABRF, dissection of metabolic function, rodents, small animals,
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