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NYU Langone’s Advanced Rodent Transgenics Laboratory ART-Lab Core Facility (RRID:SCR_017692)
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URL: https://nyumc.ilab.agilent.com/service_center/4273

Proper Citation: NYU Langone’s Advanced Rodent Transgenics Laboratory ART-Lab Core Facility (RRID:SCR_017692)

Description: Core offers services for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Provides expertise in generating novel mutant and transgenic mouse strains using genome engineering in mouse embryos and in embryonic stem cells (ESCs). Available technologies include:Generation of genome-edited mice by embryo pronuclear microinjection of DNA and genome editors (e.g., CRISPR/Cas9, site-specific recombinases) or traditional BAC transgenesis;Generation of genome-edited mice from mouse embryonic stem cells (mESCs) by chimeric blastocyst injection;Generation of genome-edited mice from mESCs by tetraploid blastocyst injection; Generation of mice from induced pluripotent stem cells;Assisted reproductive technologies; Sperm and embryo cryopreservation, storage and import/export;in vitro fertilization (IVF); Embryo rederivation technologies for animal import into barrier vivaria through quarantine.

Synonyms: NYU School of Medicine Rodent Genetic Engineering Laboratory Core Facility, Advanced Rodent Transgenics Laboratory (ART-Lab), NYU Langone Rodent Genetic Engineering Laboratory, New York University School of Medicine Langone Health Rodent Genetic Engineering Laboratory Core Facility, ART-Lab, RGEL, New York University Langone Medical Center Rodent Genetic Engineering Laboratory

Resource Type: access service resource, core facility, service resource

Keywords: Rodent, model, generation, mutant, mouse, strain, gene, targeting, embryonic, stem, cell, genetically, modified, CRISPR, Cas9, editing, in vivo, EZ-mouse model, in vitro, fertilization, cryopreservation, sperm, service, core, ABRF, USEDit

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