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URL: http://meme.nbcr.net/meme/cgi-bin/gomo.cgi
Proper Citation: GOMO - Gene Ontology for Motifs (RRID:SCR_008864)
Description: Gene Ontology for Motifs (GOMO) is an alignment- and threshold-free comparative genomics approach for assigning functional roles to DNA regulatory motifs from DNA sequence. The algorithm detects associations between a user-specified DNA regulatory motif (expressed as a position weight matrix; PWM) and Gene Ontology terms. The original method for predicting the roles of transcription factors (TFs starts with a PWM motif describing the DNA-binding affinity of the TF. GOMO uses the PWM to score the promoter region of each gene in the genome for its likelihood to be bound by the TF. The resulting ''''affinity'''' scores are then used to test each term in the Gene Ontology for association with high-scoring genes. The algorithm was subsequently extended to leverage conserved signals using multiple, related species in a comparative approach, which greatly improves the resulting annotations. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible
Abbreviations: GOMO
Synonyms: Gene Ontology for Motifs
Resource Type: analysis service resource, data analysis service, data processing software, production service resource, service resource, software application, software resource
Defining Citation: PMID:20147307, PMID:18544606
Keywords: gene, motif, genomics, gene ontology, function, compare, ontology or annotation editor, statistical analysis, dna binding motif, dna binding, dna, transcription factor, sequence
Funding: Australian Research Council ; University of Queensland; Brisbane; Australia ; International Research Tuition Award ; NCRR R01 RR021692
Availability: Free for academic use
Resource Name: GOMO - Gene Ontology for Motifs
Resource ID: SCR_008864
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
