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URL: http://tiger.dbs.nus.edu.sg/AllerHunter
Proper Citation: AllerHunter: Cross-reactive Allergen Prediction Home (RRID:SCR_002950)
Description: A cross-reactive allergen prediction program built on a combination of Support Vector Machine (SVM) and pairwise sequence similarity. Cross-reactivity is based on similarity of proteins to allergens. However, not all proteins with similar sequence or structure to known allergens are cross-reactive allergens. AllerHunter aims to predict allergens and non-allergens with high sensitivity and specificity, without compromising efficiency at classification of proteins with similar sequence to known allergens. There are distinct differences between prediction of allergenicity and cross-reactivity of allergens. Allergenicity is the immunogenic potential of an allergen to induce IgE antibody production, whereas cross-reactivity is the potential of a substance to bind to IgE previously induced by a known allergen. It is difficult to predict allergenicity because causes of immunogenicity of allergens are still not completely clear. However it is possible to predict cross-reactivity since it implies similarity in IgE binding sites. Please provide protein sequence in fasta format.
Abbreviations: AllerHunter
Synonyms: AllerHunter: Cross-reactive Allergen Prediction Program
Resource Type: analysis service resource, data analysis service, production service resource, service resource
Defining Citation: PMID:19516900
Keywords: fasta, allergen, prediction program, support vector machine
Availability: THIS RESOURCE IS NO LONGER IN SERVICE
Resource Name: AllerHunter: Cross-reactive Allergen Prediction Home
Resource ID: SCR_002950
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
