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URL: http://www.addgene.org/233472
Proper Citation: RRID:Addgene_233472
Insert Name: HLA-A2 CAR
Organism: Synthetic
Bacterial Resistance: Ampicillin
Defining Citation: PMID:38645184
Vector Backbone Description: Backbone Marker:addgene; Backbone Size:5100; Vector Backbone:pMSCV-IRES; Vector Types:Retroviral; Bacterial Resistance:Ampicillin
Comments: The HLA-A2 CAR was generated with optimised coding sequence of the variable regions of the Ig heavy and light chains from the anti–HLA-A2 BB7.2 hybridoma (ATCC). The resulting scFv was fused to a Myc epitope tag in the extracellular region to enable cell-surface detection by flow cytometry, a stalk region from mouse CD8α, the transmembrane and intracellular domains of mouse CD28, and mouse CD3ζ.
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No rating or validation information has been found for pMSCV-IRES-Thy1.1 HLAA2 CAR.
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Source: Addgene
