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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/038929
Source Database: JAX Mice and Services
Affected Genes: retinoic acid receptor; beta|retinoid X receptor gamma
Genomic Alteration: endonuclease-mediated mutation 1; Nenad Sestan
Availability: live
Notes: gene symbol note: retinoic acid receptor; beta|retinoid X receptor gamma; mutant stock: Rarb|Rxrg
Proper citation: RRID:IMSR_JAX:038929 Copy
https://www.jax.org/strain/039033
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 1
Genomic Alteration: targeted mutation 1.2; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 1; coisogenic strain|mutant strain: Htra1
Proper citation: RRID:IMSR_JAX:039033 Copy
https://www.jax.org/strain/039032
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 2
Genomic Alteration: targeted mutation 1.1; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 2; coisogenic strain|mutant strain: Htra2
Proper citation: RRID:IMSR_JAX:039032 Copy
https://www.jax.org/strain/038908
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 17; Michael Koob 2|amyloid beta precursor protein
Genomic Alteration: interspecies replacement; human Chr 17; Michael Koob 2|endonuclease-mediated mutation 1; MODEL-AD Center
Availability: live
Synonyms: B6.Cg-Tc(HSA17)2Mdk App
Notes: gene symbol note: interspecies replacement; human Chr 17; Michael Koob 2|amyloid beta precursor protein; mutant strain|congenic strain: Isr(HSA17)2Mdk|App
Proper citation: RRID:IMSR_JAX:038908 Copy
https://www.jax.org/strain/039199
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 4.2.28; Myriam Hemberger
Genomic Alteration: transgene insertion 4.2.28; Myriam Hemberger
Availability: live
Synonyms: B6N.Cg-Tg(Sox2-flpo)4.2.28Mhem/J
Notes: gene symbol note: transgene insertion 4.2.28; Myriam Hemberger; mutant strain: Tg(Sox2-flpo)4.2.28Mhem
Proper citation: RRID:IMSR_JAX:039199 Copy
https://www.jax.org/strain/039055
Source Database: JAX Mice and Services
Affected Genes: major histocompatibility complex; class II; DQ alpha 1|histocompatibility 2; K1; K region|transgene insertion 1; Chella David|protein kinase; DNA activated; catalytic polypeptide|histocompatibility 2; class II antigen A; beta 1|histocompatibility 2; D region locus 1|interleukin 2 receptor; gamma chain|major histocompatibility complex; class II; DQ beta 1
Genomic Alteration: transgene insertion 1; Chella David|endonuclease-mediated mutation 1; David V Serreze|severe combined immunodeficiency|endonuclease-mediated mutation 1; Jackson|endonuclease-mediated mutation 5; David V Serreze|targeted mutation 1; Warren J Leonard
Availability: live
Notes: gene symbol note: major histocompatibility complex; class II; DQ alpha 1|histocompatibility 2; K1; K region|transgene insertion 1; Chella David|protein kinase; DNA activated; catalytic polypeptide|histocompatibility 2; class II antigen A; beta 1|histocompatibility 2; D region locus 1|interleukin 2 receptor; gamma chain|major histocompatibility complex; class II; DQ beta 1; mutant strain|congenic strain: HLA-DQA1|H2-K1|Tg(HLA-DQA1;HLA-DQB1)1Dv|Prkdc|H2-Ab1|H2-D1|Il2rg|HLA-DQB1
Proper citation: RRID:IMSR_JAX:039055 Copy
https://www.jax.org/strain/039172
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 6; Michael Koob 1
Genomic Alteration: interspecies replacement; human Chr 6; Michael Koob 1
Availability: live
Synonyms: C57BL/6-Tc(HSA6)1Mdk/J
Notes: gene symbol note: interspecies replacement; human Chr 6; Michael Koob 1; mutant strain: Isr(HSA6)1Mdk
Proper citation: RRID:IMSR_JAX:039172 Copy
https://www.jax.org/strain/039175
Source Database: JAX Mice and Services
Affected Genes: amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 1|presenilin 1
Genomic Alteration: targeted mutation 1.1; Michael D Koob|interspecies replacement; human Chr 17; Michael Koob 1
Availability: live
Synonyms: B6J.B6N(CBA)-Tc(HSA17)1Mdk Psen1
Notes: gene symbol note: amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 1|presenilin 1; mutant strain|congenic strain: App|Isr(HSA17)1Mdk|Psen1
Proper citation: RRID:IMSR_JAX:039175 Copy
https://www.jax.org/strain/039108
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y
Genomic Alteration: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y-deletion 1; Robin Lovell-Badge
Availability: live
Notes: gene symbol note: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y; mutant strain|congenic strain: Tg(Sry)2Ei|Sry
Proper citation: RRID:IMSR_JAX:039108 Copy
https://www.jax.org/strain/039039
Source Database: JAX Mice and Services
Affected Genes: crystallin; gamma C
Genomic Alteration: mutation 2 Jackson
Availability: live
Notes: gene symbol note: crystallin; gamma C; mutant strain: Crygc
Proper citation: RRID:IMSR_JAX:039039 Copy
https://www.jax.org/strain/039168
Source Database: JAX Mice and Services
Affected Genes: synuclein; alpha
Genomic Alteration: targeted mutation 3.1; Michael D Koob
Availability: live
Notes: gene symbol note: synuclein; alpha; mutant strain|congenic strain: Snca
Proper citation: RRID:IMSR_JAX:039168 Copy
https://www.jax.org/strain/039090
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano
Genomic Alteration: targeted mutation 1; Sarah Spiegel
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano; mutant strain|congenic strain: Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:039090 Copy
https://www.jax.org/strain/039143
Source Database: JAX Mice and Services
Affected Genes: collagen; type I; alpha 1|Kras proto-oncogene; GTPase|transformation related protein 53|gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator|
Genomic Alteration: targeted mutation 1; Tuomas Tammela|targeted mutation 4; Tyler Jacks|targeted mutation 1; Anton Berns|targeted mutation 2; Scott Lowe
Availability: live
Synonyms: B6.Cg-Gt(ROSA)26Sor
Notes: gene symbol note: collagen; type I; alpha 1|Kras proto-oncogene; GTPase|transformation related protein 53|gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator|; mutant stock: Col1a1|Kras|Trp53|Gt(ROSA)26Sor|rtTA|
Proper citation: RRID:IMSR_JAX:039143 Copy
https://www.jax.org/strain/039144
Source Database: JAX Mice and Services
Affected Genes: transformation related protein 53|collagen; type I; alpha 1||gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator|Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 1; Anton Berns|targeted mutation 2; Tuomas Tammela|targeted mutation 2; Scott Lowe|targeted mutation 4; Tyler Jacks
Availability: live
Synonyms: B6.Cg-Gt(ROSA)26Sor
Notes: gene symbol note: transformation related protein 53|collagen; type I; alpha 1||gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator|Kras proto-oncogene; GTPase; mutant stock: Trp53|Col1a1||Gt(ROSA)26Sor|rtTA|Kras
Proper citation: RRID:IMSR_JAX:039144 Copy
https://www.jax.org/strain/039526
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano
Genomic Alteration: endonuclease-mediated mutation 1; Sidi Chen
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano; coisogenic strain|mutant strain: Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:039526 Copy
https://www.jax.org/strain/039577
Source Database: JAX Mice and Services
Affected Genes: EYA transcriptional coactivator and phosphatase 2
Genomic Alteration: targeted mutation 2; Pin-Xian Xu
Availability: live
Notes: gene symbol note: EYA transcriptional coactivator and phosphatase 2; mutant stock: Eya2
Proper citation: RRID:IMSR_JAX:039577 Copy
https://www.jax.org/strain/039554
Source Database: JAX Mice and Services
Affected Genes: mab-21-like 2
Genomic Alteration: targeted mutation 1.1; King L Chow
Availability: live
Notes: gene symbol note: mab-21-like 2; mutant strain|congenic strain: Mab21l2
Proper citation: RRID:IMSR_JAX:039554 Copy
https://www.jax.org/strain/039319
Source Database: JAX Mice and Services
Affected Genes: immunoglobulin heavy chain complex|immunoglobulin kappa chain complex
Genomic Alteration: endonuclease-mediated mutation 1; Dan Rohrer|endonuclease-mediated mutation 2; Dan Rohrer|endonuclease-mediated mutation 4; Dan Rohrer
Availability: live
Notes: gene symbol note: immunoglobulin heavy chain complex|immunoglobulin kappa chain complex; mutant stock: Igh|Igk
Proper citation: RRID:IMSR_JAX:039319 Copy
https://www.jax.org/strain/039562
Source Database: JAX Mice and Services
Affected Genes: submaxillary gland androgen regulated protein 2
Genomic Alteration: targeted mutation 1; David D Ginty
Availability: live
Notes: gene symbol note: submaxillary gland androgen regulated protein 2; mutant stock: Smr2
Proper citation: RRID:IMSR_JAX:039562 Copy
https://www.jax.org/strain/039564
Source Database: JAX Mice and Services
Affected Genes: transient receptor potential cation channel; subfamily M; member 8
Genomic Alteration: targeted mutation 1; David D Ginty
Availability: live
Notes: gene symbol note: transient receptor potential cation channel; subfamily M; member 8; mutant stock: Trpm8
Proper citation: RRID:IMSR_JAX:039564 Copy
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Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
