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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
SD-Myh7bem1Blar+/+
 
Resource Report
Resource Website
RRID:RGD_149735898 Rattus norvegicus This is the homozygous wild type littermate from crossing of heterozygous SD-Myh7b mutants. The Myh7b knockout SD rats were generated using the CRISPR/Cas9 system targeting exon 2, resulting 7 bases deletion of exon 2 and generated a new termination codon TGA in exon 3. The heterzygous Myh7b+/- rats were crossed to generate littermate controls. The birth ratio of wild type (WT):Myh7b+/-:Myh7b-/- was approximately 1:2:1, indicating that Myh7b-/- did not cause fetal death. 149735898 mutant Rat Genome Database (RGD) RGD Unknown 149735898 2026-07-25 12:43:08 0
SS-Xdhem2Mcwi
 
Resource Report
Resource Website
RRID:RGD_14398481 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 12-bp deletion in exon 4 of rat Xdh gene in the SS/JrHsdMcwi embryos. Contact MCW rat distribution at [email protected] 14398481 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 14398481 2026-07-25 12:43:09 0
LEW-Glp1rem3Mcwi
 
Resource Report
Resource Website
RRID:RGD_14394491 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 4-bp deletion in exon 2 of the Glp1r gene in Lew/NCrl embryos. Contact MCW rat distribution at [email protected] 14394491 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2026-02-19) 14394491 2026-07-25 12:43:08 0
LE-Scn2aem1Mcwi
 
Resource Report
Resource Website
1+ mentions
RRID:RGD_25394530 Rattus norvegicus The rat strain was produced by injecting CRISPR/Cas9 targeting rat Scn2a into Crl:LE embryos. The mutant allele was produced by injecting CRISPR/Cas9 targeting rat Scn2a into Crl:LE embryos. The resulting mutation is net 4-bp deletion in exon 5 comprising a 10-bp deletion (shown in lower case: CTACGGGATccctggaattGGTTGGATTTCACAGTCATT ) and a 6-bp insertion (TTCACT). Autism Rat Model Resource. Contact MCW rat distribution at [email protected] 25394530 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2025-02-20) 25394530 2026-07-25 12:43:08 1
SD-Cyp3a23/3a1em1Myliu,Cyp3a2em1Myliu
 
Resource Report
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RRID:RGD_14696722 Rattus norvegicus This rat strain is a double knock out for Cyp3a23/3a1 and Cyp3a2 created by using CRISPR/Cas9 targeting exons of Cyp3a23/3a1 and Cyp3a2. This strain carries a 22-bp deletion of Cyp3a23/3a1 and a 10-bp deletion of Cyp3a2 on Sprague Dawley background. 14696722 mutant Rat Genome Database (RGD) RGD Unknown 14696722 2026-07-25 12:43:08 0
W-Trpa1em1Kcrd
 
Resource Report
Resource Website
RRID:RGD_38676448 Rattus norvegicus This Trpa1-deleted Wistar (background: Crl:WI) strain was generated by using Zinc Finger Nuclease at Kirin Company, Limited in 2013. Exon 22-24, which form ion channel pore required for the activation in Trpa1 gene, was deleted. National BioResource Project for the Rat in Japan 38676448 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2020-09-17) 38676448 2026-07-25 12:43:08 0
SD-Ubdem1
 
Resource Report
Resource Website
1+ mentions
RRID:RGD_126925138 Rattus norvegicus This Ubd (FAT10) knockout rat strain was generated using theCRISPR-Cas9 technique in a Sprague Dawley (SD) background. The knockout allele has a 911 bp deletion of exon 2, leading to a truncated protein of Ubd. 126925138 mutant Rat Genome Database (RGD) RGD Unknown 126925138 2026-07-25 12:43:09 1
LE-Dyrk1aem1Mcwi
 
Resource Report
Resource Website
RRID:RGD_40818253 Rattus norvegicus The rat strain was produced by injecting CRISPR/Cas9 targeting rat Dyrk1a into Crl:LE embryos. The result is a 14-bp deletion in exon 3 Contact MCW rat distribution at [email protected] 40818253 mutant Rat Genome Database (RGD) RGD Unknown 40818253 2026-07-25 12:43:09 0
DA.F344-Dpp4DPPIV/SvH
 
Resource Report
Resource Website
RRID:RGD_41408337 Rattus norvegicus Generation of the congenic strain was started with an initial cross between F344/Crl(Wiga)SvH-Dpp4m females, homozygous for the loss-of-function mutation in the Dpp4 gene on RNO3 and a DA/Ztm wild type male rat. The DP4 deficient congenic DA strain is maintained via brother=sister mating 41408337 mutant Rat Genome Database (RGD) RGD Unknown 41408337 2026-07-25 12:43:09 0
W-Phf24em11Iexas
 
Resource Report
Resource Website
RRID:RGD_38676451 Rattus norvegicus This strain was establishe by CRISPR-Cas9 system at Osaka University. Target sequence is CCATGGGGGTGTTGATGTCCAAG (CCA is PAM sequence). Back ground strain is Crlj:Wistar (WI). This strain is line No. 11 and has a 128-bp deletion in Phf24 gene. Off-target effects (214 candidate region) have not yet been examined. National BioResource Project for the Rat in Japan 38676451 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2020-09-17) 38676451 2026-07-25 12:43:09 0
SS-Prr5em2Mcwi
 
Resource Report
Resource Website
RRID:RGD_14398465 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Prr5 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp deletion in the exon 1 of the gene. Contact MCW rat distribution at [email protected] 14398465 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2019-04-19) 14398465 2026-07-25 12:43:08 0
SD-Myh7bem1Blar+/-
 
Resource Report
Resource Website
RRID:RGD_126925949 Rattus norvegicus The Myh7b knockout SD rats were generated using the CRISPR/Cas9 system targeting exon 2, resulting 7 bases deletion of exon 2 and generated a new termination codon TGA in exon 3. The heterzygous Myh7b+/- rats were crossed to generate littermate controls. The birth ratio of wild type (WT):Myh7b+/-:Myh7b-/- was approximately 1:2:1, indicating that Myh7b-/- did not cause fetal death. 126925949 mutant Rat Genome Database (RGD) RGD Unknown 126925949 2026-07-25 12:43:09 0
WI;WDB-Prdm14tm1(H2BVenus)Nips
 
Resource Report
Resource Website
RRID:RGD_125097491 Rattus norvegicus Targeting vector was designed to replace 1st and 4th exons encoding DNA-binding domain of Prdm14 locus with H2BVenus. The vector was introduced into WDB/Nips-ES1/Nips (RGD ID:10054010) embryonic stem cells by electroporation . Targeted ES cells were injected into Crlj:WI blastocysts to produce chimeric rats. The chimeric rats were crossed with Crlj:WI rats to produce heterozygous founder rats. These rat strains are being maintained by crossing the founder rats with Crlj:WI rats. Homozygous Prdm14 knocked-in rats have the germ cell-deficient phenotype. Section of Mammalian Transgenesis, Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki, Aichi 444-8787, JAPAN 125097491 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Embryo (as of 2021-04-01) 125097491 2026-07-25 12:43:09 0
WI-Sall1em1Nips
 
Resource Report
Resource Website
RRID:RGD_125097492 Rattus norvegicus Sall1 mutation was induced by injecting a mix of two pX330 expressing Cas9 and sgRNA targeting the sequence into Crlj:WI rat embryos. The resulting mutation is a 4456-bp deletion in exon 2 to 3. Homozygous Sall1 knocked-out rats had the anephric phenotype at E21.5, and died at postnatal Day-1. Section of Mammalian Transgenesis, Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki, Aichi 444-8787, JAPAN. 125097492 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Embryo (as of 2021-04-01) 125097492 2026-07-25 12:43:09 0
F344-Rag2em1Iexas
 
Resource Report
Resource Website
RRID:RGD_38599189 Rattus norvegicus This strain was established by targeting Rag2 gene in F344/Jcl using CRISPR/Cas9 system. gRNA to Rag2: AACATAGCCTTAATTCAACCAGG (PAM: last AGG); Cas 9 mRNA transcribed from T7-NLS hCas9-pA (RDB13130) was used for the system. Gene transfer was performed by electroporation. This strain shows severe combined immunodeficiency (SCID) caused by 1-bp insertion in Rag2 gene on chromosome 3. This strain grows normally under SPF condition. National BioResource Project for the Rat in Japan 38599189 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2020-09-14) 38599189 2026-07-25 12:43:09 0
WI;WDB-Sall1tm4(tdTomato)Nips
 
Resource Report
Resource Website
RRID:RGD_125097494 Rattus norvegicus Targeting vector was designed to replace 2nd and 3rd exons encoding DNA-binding domain of Sall1 locus with tdTomato. The vector was introduced into WDB/Nips-ES1/Nips (RGD ID:10054010) embryonic stem cells by electroporation.Targeted ES cells were injected into Crlj:WI blastocysts to produce chimeric rats. The chimeric rats were crossed with Crlj:WI rats to produce heterozygous founder rats..These rat strains are being maintained by crossing the founder rats with Crlj:WI rats. Homozygous Sall1 knocked-in rats had the anephric phenotype at E21.5, and died at postnatal Day-1. Section of Mammalian Transgenesis, Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki Aichi 444-8787, JAPAN 125097494 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Embryo (as of 2021-04-01) 125097494 2026-07-25 12:43:09 0
WIC;WI;WDB-Kiss1tm8Nips
 
Resource Report
Resource Website
RRID:RGD_125097497 Rattus norvegicus This strain was made by electroporation of WDB/Nips-ES1/Nips (RGD ID:10054010) embryonic stem (ES) cells with a targeting vector. A targeting vector was designed to insert two loxP sites encompassing exons 2 and 3 of the Kiss1 gene coding for 52-amino acid rat kisspeptin-1 (Kiss1) and a neomycin-resistance gene into the Kiss1 locus in rat ES cells via homologous recombination. Targeted ES cells were injected into Crlj:WI blastocysts to produce chimeric rats. The chimeric rats were crossed with Iar:Wistar-Imamichi rats to produce heterozygous founder rats. This rat strain is being maintained by crossing the founder rat with Iar:Wistar-Imamichi rats. 125097497 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Embryo (as of 2021-04-01) 125097497 2026-07-25 12:43:08 0
WI-Grm2em1
 
Resource Report
Resource Website
RRID:RGD_41410881 Rattus norvegicus This mutant rat strain was produced by Transposagen Biopharmaceutical and available in mGluR2+/- breeding pairs. The genome modification created a premature stop codon insertion that causes a nonsense mutation at amino acid C407, deleting the transmembrane and intracellular domains of the receptor and rendering the gene nonfunctional. 41410881 mutant Rat Genome Database (RGD) RGD Unknown 41410881 2026-07-25 12:43:08 0
WIC-Cspg4em3Kyst
 
Resource Report
Resource Website
RRID:RGD_39128163 Rattus norvegicus By CRISPR/Cas9 system, mutation was introduced in Cspg4 gene of Wistar-Imamichi rat. 2 bp insertion on Exon1. National BioResource Project for the Rat in Japan 39128163 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2020-09-23) 39128163 2026-07-25 12:43:09 0
SS-Vwfem2Mcwi-/-
 
Resource Report
Resource Website
RRID:RGD_18182944 Rattus norvegicus CRISPR/Cas9 mediated gene editing was used to delete a 130,954bp region of the VWF gene in DahlSS/Mcw (SS/JrHsdMcwi ) rat embryos Contact MCW rat distribution at [email protected] 18182944 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2020-01-14) 18182944 2026-07-25 12:43:08 0

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