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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207516
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Alternate IDs: 13207516
Notes: This strain was produced by crossing of SD-Rag2em3Mcwi and SD-Il2rgem2Mcwi. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207516 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904912
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2017-05-24)
References:
Synonyms:
Alternate IDs: 12904912
Notes: This ZFN model possesses a 151 bp deletion spanning exon 1/intron 1 junction of Leptin gene. Homozygous knockout rats display loss of Leptin protein via Western blot. Homozygous knockout rats demonstrate significant weight gain compared to wild type littermates. Homozygous knockout rats show significantly elevated serum cholesterol levels Inotiv
Proper citation: RRID:RGD_12904912 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13506832
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Alternate IDs: 13506832
Notes: CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 10-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13506832 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13506831
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-02-21)
References:
Synonyms:
Alternate IDs: 13506831
Notes: CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 11-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13506831 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904891
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-05-24)
References:
Synonyms:
Alternate IDs: 12904891
Notes: This ZFN model carries the knockout of the rat Slc22a2. Horizon Discovery
Proper citation: RRID:RGD_12904891 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904892
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2017-05-24)
References:
Synonyms:
Alternate IDs: 12904892
Notes: This ZFN model carries the knockout of the rat Slc22a6. Horizon Discovery
Proper citation: RRID:RGD_12904892 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904897
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Extinct (as of 2024-04-16)
References:
Synonyms:
Alternate IDs: 12904897
Notes: This ZFN model carries the monoallelic 11 base pair deletion in Tp53 gene. Animals exhibit broad tumor spectrum with high degree of tumor malignancy. Horizon Discovery
Proper citation: RRID:RGD_12904897 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13210578
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 13210578
Notes: This CRISPR/Cas9 model possesses a 3 bp(ATC) deletion resulting in the deletion of isoleucine at position 14. The Lep mutant rats exhibited similar mutant phenotypes to Lep and Lepr null rats.
Proper citation: RRID:RGD_13210578 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800845
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2023-06-21)
References:
Synonyms:
Alternate IDs: 13800845
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of rat Mybphl gene in the FHH/EurMcwi embryos. embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13800845 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792803
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2023-06-21)
References:
Synonyms:
Alternate IDs: 13792803
Notes: This allele was made by CRISPR/Cas9 system. The resulting mutation is a 10-bp deletion in Exon 2 of the P2rx7 gene.
Proper citation: RRID:RGD_13792803 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792801
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-09-28)
References:
Synonyms:
Alternate IDs: 13792801
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion of exon 1 in the Nlrp3 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792801 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12910101
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 12910101
Notes: This model possesses a 19-bp deletion in the seventh exon of the ldlr gene by ZFN method.
Proper citation: RRID:RGD_12910101 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12907570
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 12907570
Notes: This model contains one 19- bp deletion and one 428-bp deletion within Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot.
Proper citation: RRID:RGD_12907570 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12907568
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 12907568
Notes: This model contains biallelic 19- bp deletion in exon 7 of Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot.
Proper citation: RRID:RGD_12907568 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=629459
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 629459
Notes: Obtained from Louisiana Sate University Medical Center, New Orleans by the Department of Physiology.
Proper citation: RRID:RGD_629459 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=629462
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Unknown
References:
Synonyms:
Alternate IDs: 629462
Notes: This recessive fatty Zucker rat carries a mutation that occurred spontaneously in the 13M stock and was reported by Lois Zucker and Theodore Zucker in 1960. This was observed during genetic experiments related to coat color and body size.
Proper citation: RRID:RGD_629462 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054420
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2017-01-26)
References:
Synonyms:
Alternate IDs: 10054420
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Mprl28 gene of LEW/NCrl rat embryos. The resulting mutation is a 7-bp insertion in the 2-bp deletion site in the Mrpl28 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054420 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054405
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-22)
References:
Synonyms:
Alternate IDs: 10054405
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Helz2 gene of FHH-Chr 3BN/Mcwi rat embryos.The resulting mutation is a 1-bp insertion in the Helz2 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054405 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054408
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Alternate IDs: 10054408
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Kcnj10 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion in the Kcnj10 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054408 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054417
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Alternate IDs: 10054417
Notes: CRISPR/Cas9 system was used to introduce a delins sequence alteration in the Mmp9 gene of SS/JrHsdMcwi rat embryos. The mutation is a 1-bp (t) deletion and a 5-bp (cgggta) insertion in in exon 4, which causes frameshift of the coded protein and premature stop codon in exon 8. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_10054417 Copy
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