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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
SS-Trpc3em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_11553892 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Trpc3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion in Exon 2 of the Trpc3 gene. Contact MCW rat distribution at [email protected] 11553892 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2018-10-10) 11553892 2026-07-25 12:43:03 0
SS-Rfwd2em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790717 Rattus norvegicus This strain was produced by targeting the Rfwd2 sequence in SS/JrHsdMcwi rat embryos. The resulting mutation is a 6-bp insertion ( 7-bp insertion in the 1-bp deletion site) in exon 4. 12790717 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12790717 2026-07-25 12:43:02 0
SS-Rag2em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790713 Rattus norvegicus This strain was produced by targeting the Rag2 sequence in SS/JrHsdMcwi rat embryos. The resulting mutation is a 8-bp deletion in exon 2. 12790713 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12790713 2026-07-25 12:43:03 0
WKY-Tertem2Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790954 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Tert gene of WKY/NCrl rat embryos. The resulting mutation is a 17-bp deletion in Tert gene. Contact MCW rat distribution at [email protected] 12790954 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2017-02-22) 12790954 2026-07-25 12:43:02 0
SS-Trpc3em2Mcwi
 
Resource Report
Resource Website
RRID:RGD_11553889 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Trpc3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 25-bp deletion in Exon 2 of the Trpc3 gene. Contact MCW rat distribution at [email protected] 11553889 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm; Cryorecovery (as of 2018-10-10) 11553889 2026-07-25 12:43:02 0
SD-Tp53em3Mcwi
 
Resource Report
Resource Website
RRID:RGD_11553886 Rattus norvegicus ZFN system was used to introduce a mutation in the Trp53 gene of Crl:SD rat embryos.The resulting mutation is a 84-bp deletion in Exon 3 of the Tp53 gene. Contact MCW rat distribution at [email protected] 11553886 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2017-01-26) 11553886 2026-07-25 12:43:02 0
F344-Ccdc85cem1Kyo
 
Resource Report
Resource Website
RRID:RGD_11565091 Rattus norvegicus TALEN targeting the exon1 of rat Ccdc85c gene was designed and mRNA coding these TALEN was microinjected into F344/Stm embyo. Rats developed hydrocephalus and Subcortical heterotopia. Homozygous rats die within 1 month of hydrocephalus. National BioResource Project for the Rat in Japan 11565091 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2016-11-18) 11565091 2026-07-25 12:43:03 0
SS-Rbm20em10Mcwi
 
Resource Report
Resource Website
RRID:RGD_11553881 Rattus norvegicus ZFN system was used to introduce a mutation in the Rbm20 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp deletion in Exon 2 of the Rbm20 gene. Contact MCW rat distribution at [email protected] 11553881 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2017-01-26) 11553881 2026-07-25 12:43:02 0
SS-Axlem2Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790604 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Axl gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 32-bp deletion in the exon 2 of the Axl gene. Contact MCW rat distribution at [email protected] 12790604 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12790604 2026-07-25 12:43:02 0
SS-Axlem1Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790602 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Axl gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 31-bp deletion in the exon 2 of the Axl gene. Contact MCW rat distribution at [email protected] 12790602 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12790602 2026-07-25 12:43:02 0
NMC/Nrs
 
Resource Report
Resource Website
RRID:RGD_11565100 Rattus norvegicus This strain was found in a colony of F344.LEC-xhs1/1Nrs (NBRP Rat No: 0293). As to radiosensitivity gene, D4Nirs8-D4Rat45 region is LEC type. Affected females with dominant gene on Chr10 develop mammary gland cancer after pregnancy (histological type is undetermined). In many cases, this neoplastis lesion resolve spontaneously after delivery. No homozygous female is obtained at this time. Affected male rats don't show any phenotype. National BioResource Project for the Rat in Japan 11565100 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2016-11-18) 11565100 2026-07-25 12:43:03 0
SS.BN-(D13Rat25-rs198199323)-Btg2em24Mcwi
 
Resource Report
Resource Website
RRID:RGD_12437071 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 2-bp insertion in the exon 1 in the Btg2 gene of SS.BN-(D13Rat25-rs198199323)/Mcwi rat embryos. Contact MCW rat distribution at [email protected] 12437071 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12437071 2026-07-25 12:43:03 0
SD-Grm5em1Sage
 
Resource Report
Resource Website
RRID:RGD_11568067 Rattus norvegicus The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Grm5 into Sprague Dawley embryos. The resulting mutation was a knockout of Grm5 demonstrated by western blot. Horizon Discovery 11568067 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Embryo (as of 2016-12-13) 11568067 2026-07-25 12:43:02 0
SS-Sorcs2em7Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790947 Rattus norvegicus This strain was produced by injecting ZFNs targeting the sequence of Sorcs2 into SS/JrHsdMcwi rat embryos. The resulting mutation is a 33-bp frameshift deletion in exon 15. 12790947 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2017-02-22) 12790947 2026-07-25 12:43:02 0
SS-Pon3em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_12790702 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Pon3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 16-bp deletion of exon 4 in the Pon1 gene. Contact MCW rat distribution at [email protected] 12790702 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 12790702 2026-07-25 12:43:03 0
W-Ift140em1Kyo
 
Resource Report
Resource Website
RRID:RGD_12879432 Rattus norvegicus This strain was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 1 (em1) has 2-bp insertion (c.23_24insGG) in the exon 1 of Ift140 (intraflagellar transport 140) gene. National BioResource Project for the Rat in Japan 12879432 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2017-04-19) 12879432 2026-07-25 12:43:04 0
W-Ift140em2Kyo
 
Resource Report
Resource Website
RRID:RGD_12879434 Rattus norvegicus This strain was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 2 (em2) has 2-bp deletion (c.23_24del) in the exon 1 of Ift140 (intraflagellar transport 140) gene. National BioResource Project for the Rat in Japan 12879434 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2017-04-19) 12879434 2026-07-25 12:43:04 0
F344-Rag2em1Sage
 
Resource Report
Resource Website
RRID:RGD_12904905 Rattus norvegicus This ZFN model carries a 2 bp deletion within exon 3 of the Rag2 gene.on chromosome 3 Rag2 knockout rats completely lack B and T cells. Horizon Discovery 12904905 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2017-05-24) 12904905 2026-07-25 12:43:03 0
SD-Prkdcem1Sage
 
Resource Report
Resource Website
RRID:RGD_12904907 Rattus norvegicus This ZFN induced knockout rats carrying a shorter truncated gene, 872 by PCR vs 1627 in wild type, have severe combined immunodeficiency (SCID) and lack of both B and T cells Horizon Discovery 12904907 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2017-05-24) 12904907 2026-07-25 12:43:03 0
SS-Shc1em5Mcwi
 
Resource Report
Resource Website
RRID:RGD_11553916 Rattus norvegicus ZFN system was used to introduce a T>G transversion mutation in the Shc1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a substitution to generate S36A in Exon 2 of theShc1 gene. Contact MCW rat distribution at [email protected] 11553916 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2017-01-25) 11553916 2026-07-25 12:43:03 0

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