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B6.129S4-Kras^tm4Tyj/J Resource Report Resource Website 100+ mentions Issue	RRID:IMSR_JAX:008179	Mus musculus		gene symbol note: Kras proto-oncogene; GTPase; congenic strain: Kras		Kras proto-oncogene; GTPase	targeted mutation 4; Tyler Jacks	JAX:008179		JAX Mice and Services	JAX	live			2026-09-04 09:44:50	187
C3.129S7(B6)-Ifng^tm1Ts/J Resource Report Resource Website 1+ mentions Issue	RRID:IMSR_JAX:008228	Mus musculus		gene symbol note: interferon gamma; mutant strain\|congenic strain: Ifng		interferon gamma	targeted mutation 1; Timothy Stewart	JAX:008228		JAX Mice and Services	JAX	sperm			2026-09-04 09:44:51	1
B6.129(SJL)-Oxtr^tm1.1Wsy/J Resource Report Resource Website 50+ mentions Issue	RRID:IMSR_JAX:008471	Mus musculus		gene symbol note: oxytocin receptor; congenic strain: Oxtr		oxytocin receptor	targeted mutation 1.1; W Scott Young III	JAX:008471		JAX Mice and Services	JAX	sperm			2026-09-04 09:44:53	89
129S/Sv-Ret^tm1Cos/J Resource Report Resource Website 1+ mentions Issue Issue	RRID:IMSR_JAX:009085	Mus musculus		gene symbol note: ret proto-oncogene; mutant strain: Ret		ret proto-oncogene	targeted mutation 1; Frank Costantini	JAX:009085		JAX Mice and Services	JAX	sperm			2026-09-04 09:44:57	1
NOD.Cg-B2m^tm1Unc Prkdc Il2rg/SzJ Resource Report Resource Website 10+ mentions Issue	RRID:IMSR_JAX:010636	Mus musculus	NOD.Cg-Prkdc B2m Il2rg/SzJ. NOD-scid Il2rg B2m. NOD-scid gamma B2m. NSG B2m	gene symbol note: protein kinase; DNA activated; catalytic polypeptide\|interleukin 2 receptor; gamma chain\|beta-2 microglobulin; mutant strain\|congenic strain: Prkdc\|Il2rg\|B2m		protein kinase; DNA activated; catalytic polypeptide\|interleukin 2 receptor; gamma chain\|beta-2 microglobulin	severe combined immunodeficiency\|targeted mutation 1; Warren J Leonard\|targeted mutation 1; University of North Carolina	JAX:010636		JAX Mice and Services	JAX	live			2026-09-04 09:45:01	11
B6.FVB-Tg(Myh6-cre)2182Mds/J Resource Report Resource Website 100+ mentions Issue	RRID:IMSR_JAX:011038	Mus musculus		gene symbol note: transgene insertion 2182; Michael D Schneider\|\|myosin; heavy polypeptide 6; cardiac muscle; alpha; mutant strain\|congenic strain: Tg(Myh6-cre)2182Mds\|\|Myh6		transgene insertion 2182; Michael D Schneider\|\|myosin; heavy polypeptide 6; cardiac muscle; alpha	transgene insertion 2182; Michael D Schneider	JAX:011038		JAX Mice and Services	JAX	live			2026-09-04 09:45:03	102
B6.129S4-Atp8b1^tm1Nbf/Mmucd Resource Report Resource Website Issue	RRID:MMRRC_036310-UCD	Mus musculus		Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection:	abnormal cochlea morphology [MP:0000031]\| organ of Corti degeneration [MP:0000043]\| enlarged liver [MP:0000599]\| abnormal liver physiology [MP:0000609]\| cholestasis [MP:0000610]\| weight loss [MP:0001263]\| postnatal growth retardation [MP:0001732]\| abnormal cochlear ganglion morphology [MP:0002855]\| increased circulating alanine transaminase level [MP:0002941]\| increased circulating alkaline phosphatase level [MP:0002968]\| increased liver weight [MP:0002981]\| bile duct proliferation [MP:0003255]\| cochlear inner hair cell degeneration [MP:0004398]\| cochlear outer hair cell degeneration [MP:0004404]\| degeneration of organ of Corti supporting cells [MP:0004465]\| abnormal outer hair cell stereociliary bundle morphology [MP:0004527]\| abnormal bile secretion [MP:0004772]\| abnormal bile salt level [MP:0004774]\| increased bile salt level [MP:0004789]\| increased circulating aspartate transaminase level [MP:0005343]\| increased circulating bilirubin level [MP:0005344]\| abnormal bile salt homeostasis [MP:0005365]\| increased sensitivity to induced morbidity/mortality [MP:0009763]\| increased susceptibility to weight loss [MP:0010180]\| increased or absent threshold for auditory brainstem response [MP:0011967]	Atp8b1		036310-UCD	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:20126555 PMID:18466903	MMRRC_36310-UCD, MMRRC_036310, MMRRC_3631	2026-09-05 04:09:19	0
129S/Sv-Atp8b1^tm1Nbf/Mmucd Resource Report Resource Website Issue	RRID:MMRRC_036309-UCD	Mus musculus		Research areas: Cell Biology, Internal/Organ, Metabolism, Models for Human Disease, Sensorineural; Mutation Type: Targeted Mutation ; Collection:	abnormal cochlea morphology [MP:0000031]\| organ of Corti degeneration [MP:0000043]\| enlarged liver [MP:0000599]\| abnormal liver physiology [MP:0000609]\| cholestasis [MP:0000610]\| weight loss [MP:0001263]\| postnatal growth retardation [MP:0001732]\| abnormal cochlear ganglion morphology [MP:0002855]\| increased circulating alanine transaminase level [MP:0002941]\| increased circulating alkaline phosphatase level [MP:0002968]\| increased liver weight [MP:0002981]\| bile duct proliferation [MP:0003255]\| cochlear inner hair cell degeneration [MP:0004398]\| cochlear outer hair cell degeneration [MP:0004404]\| degeneration of organ of Corti supporting cells [MP:0004465]\| abnormal outer hair cell stereociliary bundle morphology [MP:0004527]\| abnormal bile secretion [MP:0004772]\| abnormal bile salt level [MP:0004774]\| increased bile salt level [MP:0004789]\| increased circulating aspartate transaminase level [MP:0005343]\| increased circulating bilirubin level [MP:0005344]\| abnormal bile salt homeostasis [MP:0005365]\| increased sensitivity to induced morbidity/mortality [MP:0009763]\| increased susceptibility to weight loss [MP:0010180]\| increased or absent threshold for auditory brainstem response [MP:0011967]	Atp8b1		036309-UCD	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:20126555 PMID:18466903	MMRRC_36309-UCD, MMRRC_036309, MMRRC_3639	2026-09-05 04:09:19	0
NOD.Cg-Ifng^tm1Ts H2^h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue	RRID:MMRRC_037140-MU	Mus musculus		Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen	increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]\| abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]	Ifng		037140-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:16394017 PMID:21220693 PMID:22119715 PMID:23509363 PMID:25400914 PMID:12244202	MMRRC_37140-MU, MMRRC_037140, MMRRC_3714	2026-09-05 04:09:28	2
NOD.Cg-Pdcd1^tm1.1Shr Ifng^tm1Ts H2^h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue	RRID:MMRRC_037145-MU	Mus musculus		Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen	increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]\| abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]\| vasculitis [MP:0001864]\| pancreas inflammation [MP:0001869]\| increased retinal ganglion cell number [MP:0002983]\| insulitis [MP:0004031]\| increased susceptibility to autoimmune diabetes [MP:0004803]\| increased regulatory T cell number [MP:0004973]\| decreased B-1 B cell number [MP:0004978]\| abnormal immune tolerance [MP:0005000]\| decreased T cell proliferation [MP:0005095]\| increased T cell proliferation [MP:0005348]	\|Pdcd1\|\|Ifng\|\|		037145-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC			MMRRC_37145-MU, MMRRC_037145, MMRRC_37145	2026-09-05 04:09:28	1
NOD.Cg-Ifng^tm1Ts Ighm^tm1Cgn H2^h4/HbmMmmh Resource Report Resource Website Issue Issue Issue	RRID:MMRRC_037144-MU	Mus musculus		Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen	abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]\| decreased bone mineral density [MP:0000063]\| abnormal trabecular bone morphology [MP:0000130]\| decreased compact bone thickness [MP:0000135]\| enlarged heart [MP:0000274]\| increased cell proliferation [MP:0000351]\| abnormal intestinal epithelium morphology [MP:0000488]\| abnormal spleen morphology [MP:0000689]\| enlarged lymph nodes [MP:0000702]\| abnormal skin condition [MP:0001191]\| abnormal cardiovascular system physiology [MP:0001544]\| abnormal humoral immune response [MP:0001800]\| arrested B cell differentiation [MP:0001802]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| thymus hypoplasia [MP:0001823]\| abnormal antigen presentation [MP:0001835]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| heart inflammation [MP:0001853]\| myocarditis [MP:0001856]\| kidney inflammation [MP:0001859]\| abnormal lymphatic vessel morphology [MP:0001879]\| premature death [MP:0002083]\| abnormal respiratory system physiology [MP:0002133]\| abnormal B cell differentiation [MP:0002144]\| abnormal spleen marginal sinus morphology [MP:0002363]\| abnormal B lymphocyte antigen presentation [MP:0002453]\| decreased immunoglobulin level [MP:0002460]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| tubular nephritis [MP:0002704]\| increased urine protein level [MP:0002962]\| abnormal cytokine secretion [MP:0003009]\| cardiac fibrosis [MP:0003141]\| thrombocytopenia [MP:0003179]\| small intestinal inflammation [MP:0003306]\| increased susceptibility to induced arthritis [MP:0003724]\| increased autoantibody level [MP:0003725]\| abnormal compact bone morphology [MP:0003797]\| abnormal PR interval [MP:0003901]\| insulitis [MP:0004031]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| increased susceptibility to autoimmune diabetes [MP:0004803]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| decreased spleen weight [MP:0004953]\| increased osteoclast cell number [MP:0004984]\| increased T cell number [MP:0005015]\| decreased B cell number [MP:0005017]\| abnormal response to infection [MP:0005025]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal T cell proliferation [MP:0005094]\| decreased T cell proliferation [MP:0005095]\| cachexia [MP:0005150]\| decreased susceptibility to injury [MP:0005166]\| abnormal pancreatic islet morphology [MP:0005215]\| abnormal CD4-positive [MP:0005463]\| alpha-beta T cell physiology [MP:0005559]\| increased circulating glucose level [MP:0005616]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]\| abnormal T cell number [MP:0008071]\| absent B cells [MP:0008075]\| decreased CD4-positive [MP:0008079]\| alpha beta T cell number [MP:0008127]\| decreased CD8-positive [MP:0008171]\| alpha-beta T cell number [MP:0008201]\| decreased dendritic cell number [MP:0008211]\| abnormal mature B cell morphology [MP:0008212]\| absent follicular dendritic cells [MP:0008213]\| decreased mature B cell number [MP:0008240]\| absent mature B cells [MP:0008241]\| absent immature B cells [MP:0008401]\| abnormal spleen marginal zone macrophage morphology [MP:0008470]\| abnormal metallophilic macrophage morphology [MP:0008495]\| abnormal CD8 positive [MP:0009346]\| alpha-beta intraepithelial T cell morphology [MP:0010965]\| abnormal spleen B cell follicle morphology [MP:0012431]\| increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]	Ighm\|\|Ifng\|\|\|		037144-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:23509363	MMRRC_37144-MU, MMRRC_037144, MMRRC_37144	2026-09-05 04:09:28	0
NOD.Cg-Cd40^tm1Kik Ifng^tm1Ts H2^h4 Tg(tetO-Tcra)1Doi/HbmMmmh Resource Report Resource Website Issue	RRID:MMRRC_037149-MU	Mus musculus		Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen	increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]\| decreased bone mineral density [MP:0000063]\| decreased neutrophil cell number [MP:0000222]\| enlarged spleen [MP:0000691]\| enlarged lymph nodes [MP:0000702]\| abnormal humoral immune response [MP:0001800]\| decreased IgA level [MP:0001807]\| no abnormal phenotype detected [MP:0002169]\| abnormal thymus medulla morphology [MP:0002375]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| decreased IgE level [MP:0002492]\| glomerulonephritis [MP:0002743]\| increased urine protein level [MP:0002962]\| increased anti-double stranded DNA antibody level [MP:0004762]\| abnormal class switch recombination [MP:0004816]\| decreased B cell number [MP:0005017]\| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]\| decreased cerebral infarction size [MP:0006058]\| increased follicular B cell number [MP:0008173]\| absent germinal center B cells [MP:0008179]\| increased marginal zone B cell number [MP:0008181]\| increased transitional stage B cell number [MP:0008189]\| abnormal B cell activation [MP:0008217]\| absent spleen germinal center [MP:0008474]\| decreased IgG1 level [MP:0008495]\| decreased IgG2a level [MP:0008496]\| decreased IgG2b level [MP:0008497]\| decreased IgG3 level [MP:0008498]\| abnormal thymus epithelium morphology [MP:0009544]\| decreased platelet aggregation [MP:0009549]\| decreased trabecular bone mass [MP:0010873]\| decreased compact bone mass [MP:0010962]\| renal glomerular immunoglobulin deposits [MP:0020519]\| abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]	Cd40\|\|Ifng\|\|\|\|		037149-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC			MMRRC_37149-MU, MMRRC_037149, MMRRC_37149	2026-09-05 04:09:28	0
NOD.Cg-Ighm^tm1Cgn H2^h4 Tg(Foxp3-HBEGF/EGFP)1Doi/HbmMmmh Resource Report Resource Website Issue Issue Issue	RRID:MMRRC_037354-MU	Mus musculus		Research areas: ; Mutation Type: Targeted Mutation ; Collection: Mullen	decreased bone mineral density [MP:0000063]\| abnormal trabecular bone morphology [MP:0000130]\| decreased compact bone thickness [MP:0000135]\| enlarged heart [MP:0000274]\| increased cell proliferation [MP:0000351]\| abnormal intestinal epithelium morphology [MP:0000488]\| abnormal spleen morphology [MP:0000689]\| enlarged lymph nodes [MP:0000702]\| abnormal skin condition [MP:0001191]\| abnormal cardiovascular system physiology [MP:0001544]\| abnormal humoral immune response [MP:0001800]\| arrested B cell differentiation [MP:0001802]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| thymus hypoplasia [MP:0001823]\| abnormal antigen presentation [MP:0001835]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| heart inflammation [MP:0001853]\| myocarditis [MP:0001856]\| kidney inflammation [MP:0001859]\| abnormal lymphatic vessel morphology [MP:0001879]\| premature death [MP:0002083]\| abnormal respiratory system physiology [MP:0002133]\| abnormal B cell differentiation [MP:0002144]\| abnormal spleen marginal sinus morphology [MP:0002363]\| abnormal B lymphocyte antigen presentation [MP:0002453]\| decreased immunoglobulin level [MP:0002460]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| tubular nephritis [MP:0002704]\| increased urine protein level [MP:0002962]\| abnormal cytokine secretion [MP:0003009]\| cardiac fibrosis [MP:0003141]\| thrombocytopenia [MP:0003179]\| small intestinal inflammation [MP:0003306]\| increased susceptibility to induced arthritis [MP:0003724]\| increased autoantibody level [MP:0003725]\| abnormal compact bone morphology [MP:0003797]\| abnormal PR interval [MP:0003901]\| insulitis [MP:0004031]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| increased susceptibility to autoimmune diabetes [MP:0004803]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| decreased spleen weight [MP:0004953]\| increased osteoclast cell number [MP:0004984]\| increased T cell number [MP:0005015]\| decreased B cell number [MP:0005017]\| abnormal response to infection [MP:0005025]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal T cell proliferation [MP:0005094]\| decreased T cell proliferation [MP:0005095]\| cachexia [MP:0005150]\| decreased susceptibility to injury [MP:0005166]\| abnormal pancreatic islet morphology [MP:0005215]\| abnormal CD4-positive [MP:0005463]\| alpha-beta T cell physiology [MP:0005559]\| increased circulating glucose level [MP:0005616]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]\| abnormal T cell number [MP:0008071]\| absent B cells [MP:0008075]\| decreased CD4-positive [MP:0008079]\| alpha beta T cell number [MP:0008127]\| decreased CD8-positive [MP:0008171]\| alpha-beta T cell number [MP:0008201]\| decreased dendritic cell number [MP:0008211]\| abnormal mature B cell morphology [MP:0008212]\| absent follicular dendritic cells [MP:0008213]\| decreased mature B cell number [MP:0008240]\| absent mature B cells [MP:0008241]\| absent immature B cells [MP:0008401]\| abnormal spleen marginal zone macrophage morphology [MP:0008470]\| abnormal metallophilic macrophage morphology [MP:0008495]\| abnormal CD8 positive [MP:0009346]\| alpha-beta intraepithelial T cell morphology [MP:0010965]\| abnormal spleen B cell follicle morphology [MP:0012431]\| increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]\| abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]	Ifng\|\|EGFP\|\|HBEGF\|Foxp3\|\|Ighm\|\|		037354-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC			MMRRC_37354-MU, MMRRC_037354, MMRRC_37354	2026-09-05 04:09:28	0
NOD.Cg-Ifng^tm1Ts H2^h4 CD40lg^tm1Imx/HbmMmmh Resource Report Resource Website 1+ mentions Issue	RRID:MMRRC_037631-MU	Mus musculus		Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen	increased leukocyte cell number [MP:0000218]\| increased monocyte cell number [MP:0000220]\| extramedullary hematopoiesis [MP:0000240]\| increased granulocyte number [MP:0000322]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| abnormal lymph node size [MP:0000701]\| enlarged lymph nodes [MP:0000702]\| increased body weight [MP:0001260]\| decreased body weight [MP:0001262]\| increased metastatic potential [MP:0001272]\| abnormal response to new environment [MP:0001413]\| altered susceptibility to infection [MP:0001793]\| abnormal humoral immune response [MP:0001800]\| decreased IgG level [MP:0001805]\| decreased IgM level [MP:0001806]\| decreased IgA level [MP:0001807]\| abnormal inflammatory response [MP:0001845]\| increased inflammatory response [MP:0001846]\| brain inflammation [MP:0001847]\| kidney inflammation [MP:0001859]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| stomach inflammation [MP:0001873]\| decreased inflammatory response [MP:0001876]\| abnormal lactation [MP:0001882]\| mammary gland alveolar hyperplasia [MP:0001884]\| decreased litter size [MP:0001935]\| abnormal lung volume [MP:0001942]\| increased airway responsiveness [MP:0001952]\| emphysema [MP:0001958]\| increased B cell derived lymphoma incidence [MP:0002023]\| increased T cell derived lymphoma incidence [MP:0002024]\| increased lung adenocarcinoma incidence [MP:0002027]\| increased sarcoma incidence [MP:0002032]\| increased carcinoma incidence [MP:0002038]\| increased pituitary adenoma incidence [MP:0002041]\| decreased tumor incidence [MP:0002052]\| premature death [MP:0002083]\| abnormal spleen size [MP:0002224]\| abnormal pulmonary alveolus morphology [MP:0002270]\| decreased airway responsiveness [MP:0002335]\| abnormal lymph node cortex morphology [MP:0002343]\| abnormal lymph node primary follicle morphology [MP:0002345]\| abnormal lymph node secondary follicle morphology [MP:0002346]\| abnormal spleen red pulp morphology [MP:0002356]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal dendritic cell physiology [MP:0002376]\| increased susceptibility to bacterial infection [MP:0002412]\| increased susceptibility to viral infection [MP:0002418]\| abnormal adaptive immunity [MP:0002420]\| altered susceptibility to autoimmune disorder [MP:0002425]\| abnormal macrophage physiology [MP:0002451]\| abnormal dendritic cell antigen presentation [MP:0002455]\| abnormal B cell physiology [MP:0002459]\| decreased immunoglobulin level [MP:0002460]\| increased immunoglobulin level [MP:0002461]\| abnormal immunoglobulin level [MP:0002490]\| decreased IgE level [MP:0002492]\| increased IgE level [MP:0002497]\| abnormal type IV hypersensitivity reaction [MP:0002534]\| glomerulonephritis [MP:0002743]\| decreased vertical activity [MP:0002757]\| albuminuria [MP:0002871]\| increased circulating alanine transaminase level [MP:0002941]\| abnormal cytokine secretion [MP:0003009]\| abnormal redox activity [MP:0003186]\| small intestinal inflammation [MP:0003306]\| abnormal tumor morphology [MP:0003448]\| increased fear-related response [MP:0003459]\| abnormal pancreatic beta cell physiology [MP:0003562]\| increased ovarian carcinoma incidence [MP:0003579]\| increased autoantibody level [MP:0003725]\| decreased autoantibody level [MP:0003726]\| abnormal nitric oxide homeostasis [MP:0003957]\| abnormal lung vasculature morphology [MP:0004007]\| abnormal maternal decidual layer morphology [MP:0004256]\| decreased length of allograft survival [MP:0004752]\| decreased anti-nuclear antigen antibody level [MP:0004795]\| decreased anti-double stranded DNA antibody level [MP:0004798]\| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]\| decreased susceptibility to systemic lupus erythematosus [MP:0004802]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| abnormal immune tolerance [MP:0005000]\| increased eosinophil cell number [MP:0005011]\| increased lymphocyte cell number [MP:0005013]\| increased T cell number [MP:0005015]\| abnormal response to infection [MP:0005025]\| decreased susceptibility to parasitic infection [MP:0005026]\| increased susceptibility to parasitic infection [MP:0005027]\| abnormal MHC II cell surface expression on macrophages [MP:0005040]\| impaired natural killer cell mediated cytotoxicity [MP:0005070]\| abnormal cytotoxic T cell physiology [MP:0005078]\| decreased double-negative T cell number [MP:0005089]\| cachexia [MP:0005150]\| abnormal response to injury [MP:0005164]\| decreased susceptibility to injury [MP:0005166]\| abnormal renal glomerulus morphology [MP:0005325]\| atherosclerotic lesions [MP:0005338]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| abnormal Langerhans cell physiology [MP:0005362]\| increased susceptibility to fungal infection [MP:0005399]\| abnormal skin physiology [MP:0005501]\| corneal vascularization [MP:0005542]\| decreased circulating creatinine level [MP:0005554]\| increased blood urea nitrogen level [MP:0005565]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]\| abnormal response to transplant [MP:0005671]\| abnormal mammary gland growth during pregnancy [MP:0006269]\| increased NK T cell number [MP:0008039]\| abnormal uterine NK cell morphology [MP:0008054]\| increased CD4-positive [MP:0008074]\| alpha beta T cell number [MP:0008078]\| increased CD8-positive [MP:0008135]\| alpha-beta T cell number [MP:0008466]\| small Peyer's patches [MP:0008474]\| enlarged mesenteric lymph nodes [MP:0008496]\| absent spleen germinal center [MP:0008497]\| decreased IgG2a level [MP:0008498]\| decreased IgG2b level [MP:0008499]\| decreased IgG3 level [MP:0008523]\| increased IgG1 level [MP:0008567]\| absent lymph node germinal center [MP:0008596]\| decreased interferon-gamma secretion [MP:0008660]\| increased circulating interleukin-6 level [MP:0008661]\| increased interleukin-10 secretion [MP:0008663]\| decreased interleukin-10 secretion [MP:0008681]\| increased interleukin-12 secretion [MP:0008687]\| increased interleukin-17 secretion [MP:0008699]\| increased interleukin-2 secretion [MP:0008702]\| increased interleukin-4 secretion [MP:0008713]\| increased interleukin-5 secretion [MP:0008770]\| abnormal cytokine level [MP:0008828]\| decreased survivor rate [MP:0008874]\| abnormal lymph node cell ratio [MP:0009099]\| decreased physiological sensitivity to xenobiotic [MP:0009246]\| abnormal uterine NK cell physiology [MP:0009336]\| pale spleen [MP:0009394]\| increased splenocyte proliferation [MP:0009419]\| increased uterine NK cell number [MP:0009643]\| skeletal muscle fibrosis [MP:0009763]\| abnormal urine homeostasis [MP:0009766]\| increased sensitivity to induced morbidity/mortality [MP:0009788]\| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]\| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]\| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]\| increased tumor latency [MP:0010308]\| abnormal circulating cytokine level [MP:0010574]\| decreased tumor latency [MP:0010639]\| aorta dilation [MP:0010659]\| altered tumor pathology [MP:0010740]\| abdominal aorta aneurysm [MP:0010750]\| abnormal dendritic cell chemotaxis [MP:0010751]\| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]\| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]\| abnormal macrophage chemotaxis [MP:0011086]\| abnormal NK cell physiology [MP:0011320]\| postnatal lethality [MP:0011427]\| incomplete penetrance [MP:0012431]\| abnormal glomerular capillary morphology [MP:0013239]\| mesangial cell hyperplasia [MP:0013590]\| increased lymphoma incidence [MP:0030466]\| decreased bone mineral density [MP:0000063]\| abnormal thalamus morphology [MP:0000832]\| abnormal immune system physiology [MP:0001790]\| decreased IgA level [MP:0001807]\| abnormal antigen presentation [MP:0001835]\| neurodegeneration [MP:0002229]\| abnormal lymph node morphology [MP:0002339]\| decreased immunoglobulin level [MP:0002460]\| decreased IgE level [MP:0002492]\| abnormal blood coagulation [MP:0002551]\| spongiform encephalopathy [MP:0002654]\| abnormal immune system organ morphology [MP:0002722]\| loss of cortex neurons [MP:0003241]\| abnormal leukocyte adhesion [MP:0003628]\| abnormal nervous system physiology [MP:0003633]\| abnormal class switch recombination [MP:0004816]\| abnormal T cell clonal deletion [MP:0005002]\| abnormal thrombosis [MP:0005048]\| increased susceptibility to prion infection [MP:0005364]\| increased bleeding time [MP:0005606]\| abnormal vascular endothelial cell morphology [MP:0006055]\| decreased cerebral infarction size [MP:0006058]\| lymph node hypoplasia [MP:0008101]\| absent spleen germinal center [MP:0008474]\| decreased IgG1 level [MP:0008495]\| decreased IgG2b level [MP:0008497]\| absent lymph node germinal center [MP:0008523]\| microgliosis [MP:0008918]\| decreased platelet aggregation [MP:0009549]\| decreased trabecular bone mass [MP:0010873]\| decreased compact bone mass [MP:0010962]\| abnormal cytokine secretion [MP:0003009]\| thyroid inflammation [MP:0003504]\| insulitis [MP:0004031]\| decreased susceptibility to autoimmune diabetes [MP:0004804]\| periinsulitis [MP:0005580]\| decreased physiological sensitivity to xenobiotic [MP:0008874]	IfngCd40lg		037631-MU	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:23776180	MMRRC_37631-MU, MMRRC_037631, MMRRC_37631	2026-09-05 04:09:32	6
B6J.Cg-Slc25a13^tm1Lct/TsahMmjax Resource Report Resource Website Issue	RRID:MMRRC_069593-JAX	Mus musculus		Research areas: Diabetes, Metabolism; Mutation Type: Targeted Mutation ; Collection:	hypoglycemia [MP:0000189]\| decreased body weight [MP:0001262]\| increased circulating free fatty acid level [MP:0001554]\| postnatal growth retardation [MP:0001732]\| premature death [MP:0002083]\| hepatic steatosis [MP:0002628]\| decreased circulating insulin level [MP:0002727]\| increased circulating alkaline phosphatase level [MP:0002968]\| abnormal gluconeogenesis [MP:0003383]\| increased circulating glycerol level [MP:0003443]\| increased circulating ammonia level [MP:0005309]\| abnormal circulating amino acid level [MP:0005311]\| abnormal amino acid level [MP:0005332]\| increased liver triglyceride level [MP:0009355]\| abnormal blood homeostasis [MP:0009642]\| abnormal urine homeostasis [MP:0009643]	Slc25a13		069593-JAX	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:14701727	MMRRC_69593-JAX, MMRRC_069593, MMRRC_69593	2026-09-05 04:15:53	0
B6;129S5-Csmd1^tm1Lex/Mmucd Resource Report Resource Website 1+ mentions Issue	RRID:MMRRC_032236-UCD	Mus musculus		Research areas: Cancer, Developmental Biology, Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:	increased body weight [MP:0001260]\| increased anxiety-related response [MP:0001363]\| hyperactivity [MP:0001399]\| decreased startle reflex [MP:0001489]\| abnormal emotion/affect behavior [MP:0002572]\| behavioral despair [MP:0002573]\| increased thigmotaxis [MP:0002797]\| abnormal voluntary movement [MP:0003491]\| improved glucose tolerance [MP:0005292]	Csmd1		032236-UCD	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC			MMRRC_32236-UCD, MMRRC_032236, MMRRC_32236	2026-09-05 04:08:50	1
C.129-Thy1^a Foxp3^sf/Mmnc Resource Report Resource Website Issue	RRID:MMRRC_010500-UNC	Mus musculus		Research areas: Immunology and Inflammation, Models for Human Disease; Mutation Type: Spontaneous Mutation ; Collection:	small ears [MP:0000018]\| thick ears [MP:0000019]\| scaly ears [MP:0000020]\| decreased hematocrit [MP:0000208]\| increased leukocyte cell number [MP:0000218]\| extramedullary hematopoiesis [MP:0000240]\| enlarged heart [MP:0000274]\| gastrointestinal hemorrhage [MP:0000465]\| abnormal liver morphology [MP:0000598]\| enlarged liver [MP:0000599]\| enlarged liver sinusoidal spaces [MP:0000602]\| pale liver [MP:0000603]\| jaundice [MP:0000611]\| abnormal spleen morphology [MP:0000689]\| enlarged spleen [MP:0000691]\| enlarged lymph nodes [MP:0000702]\| abnormal thymus morphology [MP:0000703]\| small thymus [MP:0000706]\| small gonad [MP:0001116]\| abnormal male reproductive system morphology [MP:0001145]\| small testis [MP:0001147]\| scaly skin [MP:0001192]\| dermatitis [MP:0001194]\| tight skin [MP:0001198]\| skin lesions [MP:0001212]\| abnormal epidermal layer morphology [MP:0001216]\| epidermal hyperplasia [MP:0001222]\| decreased body weight [MP:0001262]\| decreased body size [MP:0001265]\| distended abdomen [MP:0001270]\| delayed eyelid opening [MP:0001290]\| hunched posture [MP:0001505]\| anemia [MP:0001577]\| multifocal hepatic necrosis [MP:0001655]\| postnatal growth retardation [MP:0001732]\| abnormal homeostasis [MP:0001764]\| increased inflammatory response [MP:0001846]\| conjunctivitis [MP:0001852]\| abnormal atrial thrombosis [MP:0001855]\| liver inflammation [MP:0001860]\| lung inflammation [MP:0001861]\| salivary gland inflammation [MP:0001870]\| male infertility [MP:0001925]\| abnormal breathing pattern [MP:0001951]\| postnatal lethality [MP:0002082]\| premature death [MP:0002083]\| cryptorchism [MP:0002286]\| abnormal lymph node morphology [MP:0002339]\| abnormal lymph node B cell domain morphology [MP:0002344]\| abnormal lymph node T cell domain morphology [MP:0002347]\| abnormal spleen white pulp morphology [MP:0002357]\| abnormal thymus cortex morphology [MP:0002371]\| abnormal megakaryocyte progenitor cell morphology [MP:0002413]\| abnormal reticulocyte morphology [MP:0002424]\| abnormal CD4-positive [MP:0002432]\| alpha beta T cell morphology [MP:0002435]\| abnormal effector T cell morphology [MP:0002446]\| abnormal macrophage morphology [MP:0002447]\| abnormal erythrocyte morphology [MP:0002459]\| abnormal B cell physiology [MP:0002461]\| increased immunoglobulin level [MP:0002493]\| increased IgG level [MP:0002494]\| increased IgM level [MP:0002590]\| increased mean corpuscular volume [MP:0002599]\| increased mean platelet volume [MP:0002619]\| abnormal lymphocyte morphology [MP:0002642]\| anisocytosis [MP:0002643]\| poikilocytosis [MP:0002670]\| absent scrotum [MP:0002722]\| abnormal immune system organ morphology [MP:0002771]\| absent prostate gland anterior lobe [MP:0002874]\| decreased hemoglobin content [MP:0002875]\| decreased erythrocyte cell number [MP:0003009]\| abnormal cytokine secretion [MP:0003179]\| thrombocytopenia [MP:0003292]\| melena [MP:0003427]\| parakeratosis [MP:0003550]\| short perineum [MP:0003642]\| absent seminal vesicle [MP:0004947]\| skin inflammation [MP:0004952]\| increased spleen weight [MP:0004969]\| pale kidney [MP:0005010]\| abnormal CD8-positive [MP:0005036]\| alpha beta T cell morphology [MP:0005097]\| diarrhea [MP:0005150]\| polychromatophilia [MP:0005202]\| cachexia [MP:0005251]\| lethargy [MP:0005287]\| blepharitis [MP:0005463]\| narrow eye opening [MP:0005639]\| abnormal CD4-positive [MP:0008074]\| alpha-beta T cell physiology [MP:0008097]\| hemosiderosis [MP:0008234]\| increased CD4-positive [MP:0008255]\| alpha beta T cell number [MP:0008470]\| increased plasma cell number [MP:0008475]\| absent spleen marginal zone [MP:0008476]\| decreased megakaryocyte cell number [MP:0008478]\| abnormal spleen B cell follicle morphology [MP:0008560]\| intermingled spleen red and white pulp [MP:0008699]\| increased spleen red pulp amount [MP:0008705]\| increased spleen white pulp amount [MP:0008751]\| increased tumor necrosis factor secretion [MP:0008752]\| increased interleukin-4 secretion [MP:0009675]\| increased interleukin-6 secretion [MP:0010169]\| abnormal interleukin level [MP:0010334]\| abnormal tumor necrosis factor level [MP:0011083]\| orthokeratosis [MP:0011086]\| decreased CD4-positive [MP:0011224]\| CD25-positive [MP:0012078]\| alpha-beta regulatory T cell number [MP:0012246]	\|\|Foxp3\|Thy1		010500-UNC	Spontaneous Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:12932350 PMID:12612578	MMRRC_10500-UNC, MMRRC_010500, MMRRC_15	2026-09-05 04:04:35	0
B6J.Cg-Ikbkg^tm1Dln Tnf^tm1Gkl/Mmucd Resource Report Resource Website Issue	RRID:MMRRC_041405-UCD	Mus musculus		Research areas: Apoptosis, Cell Biology, Dermatology, Developmental Biology, Hematology, Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:	increased bone mineral density [MP:0000062]\| abnormal trabecular bone morphology [MP:0000130]\| increased leukocyte cell number [MP:0000218]\| increased neutrophil cell number [MP:0000219]\| abnormal Peyer's patch morphology [MP:0000696]\| abnormal spermatogenesis [MP:0001156]\| decreased body weight [MP:0001262]\| abnormal vasodilation [MP:0001613]\| abnormal inflammatory response [MP:0001845]\| decreased inflammatory response [MP:0001876]\| abnormal glucose homeostasis [MP:0002078]\| premature death [MP:0002083]\| abnormal lipid homeostasis [MP:0002118]\| abnormal lymph node B cell domain morphology [MP:0002344]\| abnormal spleen marginal sinus morphology [MP:0002363]\| abnormal Peyer's patch follicle morphology [MP:0002389]\| abnormal Peyer's patch germinal center morphology [MP:0002391]\| abnormal Peyer's patch T cell area morphology [MP:0002392]\| decreased susceptibility to bacterial infection [MP:0002411]\| increased susceptibility to bacterial infection [MP:0002412]\| abnormal macrophage physiology [MP:0002451]\| decreased circulating triglyceride level [MP:0002644]\| oligozoospermia [MP:0002687]\| decreased circulating insulin level [MP:0002727]\| dilated heart left ventricle [MP:0002753]\| abnormal testes secretion [MP:0002782]\| colitis [MP:0002816]\| abnormal cytokine secretion [MP:0003009]\| rheumatoid arthritis [MP:0003561]\| oxidative stress [MP:0003674]\| abnormal lymphocyte physiology [MP:0003945]\| abnormal spermiation [MP:0004182]\| decreased incidence of tumors by chemical induction [MP:0004502]\| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]\| decreased testis weight [MP:0004852]\| abnormal testis physiology [MP:0004884]\| increased osteoblast cell number [MP:0004988]\| increased lymphocyte cell number [MP:0005013]\| increased susceptibility to parasitic infection [MP:0005027]\| cachexia [MP:0005150]\| abnormal mesenteric lymph node morphology [MP:0005232]\| abnormal fat pad morphology [MP:0005334]\| decreased susceptibility to autoimmune disorder [MP:0005351]\| decreased percent body fat/body weight [MP:0005459]\| decreased circulating glucose level [MP:0005560]\| decreased ventricle muscle contractility [MP:0005598]\| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]\| decreased circulating leptin level [MP:0005668]\| decreased Peyer's patch number [MP:0008133]\| small Peyer's patches [MP:0008135]\| absent follicular dendritic cells [MP:0008201]\| abnormal metallophilic macrophage morphology [MP:0008241]\| abnormal osteoclast differentiation [MP:0008396]\| abnormal spleen primary B follicle morphology [MP:0008471]\| abnormal spleen follicular dendritic cell network [MP:0008473]\| absent spleen germinal center [MP:0008474]\| increased circulating tumor necrosis factor level [MP:0008553]\| decreased circulating tumor necrosis factor level [MP:0008554]\| increased tumor necrosis factor secretion [MP:0008560]\| abnormal chemokine secretion [MP:0008722]\| decreased susceptibility to endotoxin shock [MP:0008734]\| increased susceptibility to endotoxin shock [MP:0008735]\| cecum inflammation [MP:0009481]\| decreased keratinocyte proliferation [MP:0009584]\| prenatal lethality [MP:0011101]\| incomplete penetrance [MP:0013486]\| decreased Paneth cell number [MP:0030466]	Tnf\|\|Ikbkg\|		041405-UCD	Targeted Mutation	Mutant Mouse Resource and Research Center (MMRRC)	MMRRC		PMID:8879212 PMID:11179023	MMRRC_41405-UCD, MMRRC_041405, MMRRC_4145	2026-09-05 04:10:19	0
B6.BTBR-Pah^enu2/Rbrc Resource Report Resource Website Issue	RRID:IMSR_RBRC06319	Mus musculus		gene symbol note: phenylalanine hydroxylase; mutant strain: Pah		phenylalanine hydroxylase	phenylalanine hydroxylase enu 2	RBRC06319		RIKEN BioResource Research Center	RBRC	embryo			2026-09-04 10:24:42	0
NC.MRL-Fas^lpr/OhnotRbrc Resource Report Resource Website Issue	RRID:IMSR_RBRC06464	Mus musculus		gene symbol note: Fas cell surface death receptor; mutant strain: Fas		Fas cell surface death receptor	lymphoproliferation	RBRC06464		RIKEN BioResource Research Center	RBRC	embryo			2026-09-04 10:24:44	0

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