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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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http://www.wormbase.org/db/get?name=WBStrain00062599

Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00020142(aak-2)
Genomic Alteration: WBGene00006843(unc-119), WBGene00020142(aak-2)
Availability: unknown
Source References: EMPTY
Synonyms: unc-119(ed3) III; aak-2(ok524) X; fphEx3.
Notes: fphEx3 [aak-2Ap::aak-2C::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. aak-2c isoform expressed from the aak-2a promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384.

Proper citation: RRID:WB-STRAIN:WBStrain00062599 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062632

Source Database: WormBase (WB)
Affected Genes: WBGene00004398(rol-8)
Genomic Alteration: WBGene00004398(rol-8)
Availability: unknown
Source References: EMPTY
Synonyms: rol-8(wrd230[rol-8mNG::3xFLAG]) II.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous rol-8 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.

Proper citation: RRID:WB-STRAIN:WBStrain00062632 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062596

Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00020142(aak-2)
Genomic Alteration: WBGene00006843(unc-119), WBGene00020142(aak-2)
Availability: unknown
Source References: EMPTY
Synonyms: unc-119(ed3) III; aak-2(ok524) X; fphIs1.
Notes: fphIs1 [aak-2Ap::aak-2A::GFP + unc-119(+)]. aak-2A isoform expressed with its own promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384.

Proper citation: RRID:WB-STRAIN:WBStrain00062596 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062597

Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00020142(aak-2)
Genomic Alteration: WBGene00006843(unc-119), WBGene00020142(aak-2)
Availability: unknown
Source References: EMPTY
Synonyms: unc-119(ed3) III; aak-2(ok524) X; fphEx1.
Notes: fphEx1 [aak-2Cp::aak-2C::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. aak-2C isoform expressed from its own promoter in aak-2(ok524) background. Reference: Jeong JH, et al. Nat Commun. 2023 Jan 18;14(1):288. doi: 10.1038/s41467-023-35952-z. PMID: 36653384.

Proper citation: RRID:WB-STRAIN:WBStrain00062597 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062630

Source Database: WormBase (WB)
Affected Genes: WBGene00001066(dpy-4)
Genomic Alteration: WBGene00001066(dpy-4)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-4(wrd228[dpy-4::mNG::3xFLAG]) IV.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous dpy-4 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.

Proper citation: RRID:WB-STRAIN:WBStrain00062630 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062635

Source Database: WormBase (WB)
Affected Genes: WBGene00009983(cut-2)
Genomic Alteration: WBGene00009983(cut-2)
Availability: unknown
Source References: EMPTY
Synonyms: cut-2(wrd233[cut-2::mNG::3xFLAG]) V.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous cut-2 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.

Proper citation: RRID:WB-STRAIN:WBStrain00062635 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062628

Source Database: WormBase (WB)
Affected Genes: WBGene00003553(nas-37)
Genomic Alteration: WBGene00003553(nas-37)
Availability: unknown
Source References: EMPTY
Synonyms: nas-37(wrd106[nas-37:::mNG::3xFLAG]) X.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous nas-37 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.

Proper citation: RRID:WB-STRAIN:WBStrain00062628 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062629

Source Database: WormBase (WB)
Affected Genes: WBGene00000788(cpz-1)
Genomic Alteration: WBGene00000788(cpz-1)
Availability: unknown
Source References: EMPTY
Synonyms: cpz-1(wrd128[cpz-1::mNG::3xFLAG::linker]) I.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted internally in exon 4 of the endogenous cpz-1 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.

Proper citation: RRID:WB-STRAIN:WBStrain00062629 Copy   

    • RRID:WB-STRAIN:WBStrain00062626

http://www.wormbase.org/db/get?name=WBStrain00062626

Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: K02D10.1(bet88) III.
Notes: Homozygous viable. Deletion of 2796 bp in parental strain N2. Left flanking sequence: tatgaactttaagaccaact; Right flanking sequence: ggatgggatgcaactgttgc. sgRNA #1: actcatactataagttcagt; sgRNA #2: ctacttgggcaaagccagga.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062626 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062580

Source Database: WormBase (WB)
Affected Genes: WBGene00003271(mir-43)|WBGene00004140(ebax-1)
Genomic Alteration: WBGene00003271(mir-43), WBGene00004140(ebax-1)
Availability: unknown
Source References: EMPTY
Synonyms: mir-43(sjm2) II; ebax-1(tm2321) IV.
Notes: Homozygotes lack gross phenotypes, though some miRNAs are elevated due to loss-of-function mutation in ebax-1. mir-43(sjm2) has positions 9-23 of miR-43 substituted for random sequence. This strain also has a G>T point substitution at position 8 of miR-42. Generated by mating parental strain CZ9907 hermaphrodites to mir-43(sjm2) males. Reference: Stubna MW, et al. bioRxiv doi: 10.1101/2024.06.28/601170.|"Made_by: Michael Stubna"

Proper citation: RRID:WB-STRAIN:WBStrain00062580 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062583

Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: cshIs128 II; lin-12(ljf33[lin-12::mNeonGreen[C1]::loxP::3xFLAG::AID*]) III; lag-2(bmd204[lag-2::mTurquoise2::lox511i::2xHA]) V.
Notes: cshIs128 [rpl-28p::TIR1::T2A::mCherry::HIS-11)] II. Endogenously tagged LIN-12::mNG::3xFlag::AID crossed to endogenously tagged LAG-2::mTurquoise2::2xHA and ubiquitously expressed TIR1 with nuclear mCherry marker. Reference: Medwig-Kinney TN, et al. An in vivo toolkit to visualize endogenous LAG-2/Delta and LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000602. doi: 10.17912/micropub.biology.000602. PMID: 35966395.|"Made_by: Taylor Medwig-Kinney and Theresa Gibney"

Proper citation: RRID:WB-STRAIN:WBStrain00062583 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062582

Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: lin-12(ljf31[lin-12::mNeonGreen[C1]::loxP::3xFLAG]) III; lag-2(bmd202[lag-2::P2A::H2B::mTurquoise2::lox511i::2xHA]) V.
Notes: Endogenously-tagger reporters allow simultaneous visualization of endogenous LIN-12 localization and lag-2 expression levels. Reference: Medwig-Kinney TN, et al. An in vivo toolkit to visualize endogenous LAG-2/Delta and LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000602. doi: 10.17912/micropub.biology.000602. PMID: 35966395.|"Made_by: Taylor Medwig-Kinney and Ariel Pani"

Proper citation: RRID:WB-STRAIN:WBStrain00062582 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062585

Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: cshIs128 II; lin-12(ljf33[lin-12::mNeonGreen[C1]::LoxP::3xFLAG::AID]) III; lag-2(bmd202[lag-2::P2A::H2B::mTurquoise2::lox511i::2xHA]) V.
Notes: cshIs128 [rpl-28p::TIR1::T2A::mCherry::his-11)] II. Auxin-dependent degradation of endogenous LIN-12 with visible readout of endogenous lag-2 expression. Reference: Pani AM, et al. A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000603. doi: 10.17912/micropub.biology.000603. PMID: 35966394.|"Made_by: Theresa Gibney and Taylor Medwig-Kinney"

Proper citation: RRID:WB-STRAIN:WBStrain00062585 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062586

Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: cshIs140 II; lin-12(ljf33[lin-12::mNeonGreen[C1]::loxP::3xFLAG::AID*]) III; lag-2(bmd202[lag-2::P2A::H2B::mTurquoise2::lox511i::2xHA]) V.
Notes: cshIs140 [rpl-28p::TIR1(F79G)::T2A::mCherry::HIS-11] II. Allows for conditional degradation of endogenous LIN-12 using 5-Ph-IAA. Reference: Pani AM, et al. A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000603. doi: 10.17912/micropub.biology.000603. PMID: 35966394.|"Made_by: Theresa Gibney and Taylor Medwig-Kinney"

Proper citation: RRID:WB-STRAIN:WBStrain00062586 Copy   

    • RRID:WB-STRAIN:WBStrain00062625

http://www.wormbase.org/db/get?name=WBStrain00062625

Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y116F11B.14(bet83) V.
Notes: Homozygous viable. Deletion of 1493 bp in parental strain N2. Left flanking sequence: attaatttttgaatttcctaca; Right flanking sequence: tgacgggctaatattgaatta. sgRNA #1: attacactataataatgtgt; sgRNA #2: aaacgacaaactcattatga.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062625 Copy   

http://www.wormbase.org/db/get?name=WBStrain00062622

Source Database: WormBase (WB)
Affected Genes: WBGene00022629(algn-12)
Genomic Alteration: WBGene00022629(algn-12)
Availability: unknown
Source References: EMPTY
Synonyms: algn-12(bet74) V/nT1[qls51] (IV;V).
Notes: Homozygous sterile. Balanced by nT1[qIs51]. Deletion of 3471 bp in parental strain N2. Left flanking sequence: tgatcactcacagttccctgg; Right flanking sequence: gaatggatatgatgatgtatat. sgRNA #1: atgttcgtggaacgacacca; sgRNA #2: aggataaactctctcttgaa.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062622 Copy   

    • RRID:WB-STRAIN:WBStrain00062617

http://www.wormbase.org/db/get?name=WBStrain00062617

Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y76A2B.4(bet65) III.
Notes: Homozygous viable. Deletion of 1579 bp in parental strain N2. Left flanking sequence: gcaaaaaaaaacataccaga; Right flanking sequence: cgtggtttcaggccattacg. sgRNA #1: cctcactgatgatcgtcatc; sgRNA #2: aaaggttcagcattcacacg.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062617 Copy   

    • RRID:WB-STRAIN:WBStrain00062618

http://www.wormbase.org/db/get?name=WBStrain00062618

Source Database: WormBase (WB)
Affected Genes: WBGene00016665(chil-11)
Genomic Alteration: WBGene00016665(chil-11)
Availability: unknown
Source References: EMPTY
Synonyms: chil-11(bet66) IV.
Notes: Homozygous viable. Deletion of 2532 bp in parental strain N2. Left flanking sequence: agtcaattcggaactccatgt; Right flanking sequence: tctacggtttaaacaactcctc. sgRNA #1: aacgggatctgttcatcaca; sgRNA #2: agtgtgaaacgcaacgtcta.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062618 Copy   

    • RRID:WB-STRAIN:WBStrain00062616

http://www.wormbase.org/db/get?name=WBStrain00062616

Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y67H2A.2(bet63) IV.
Notes: Homozygous viable. Deletion of 2572 bp in parental strain N2. Left flanking sequence: atctatttttttaaggccgaac; Right flanking sequence: tattggcagcaagcgttgcgaa. sgRNA #1: ccatacgttgttgtggagtt; sgRNA #2: tgtgaagcggaaaaccctat.|"Made_by: Bettinger lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062616 Copy   

    • RRID:WB-STRAIN:WBStrain00062572

http://www.wormbase.org/db/get?name=WBStrain00062572

Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: dmaEx617.
Notes: dmaEx617 [fshr-1p::fshr-1::GFP + unc-54p::mCherry]. Pick mCherry+ animals to maintain. Extrachromosomal fshr-1p::fshr-1::GFP translation reporter. Reference: Wang C, et al. Aging Cell. 2023 Jan;22(1):e13735. doi: 10.1111/acel.13735. PMID: 36415159.|"Made_by: Dengke Ma Lab"

Proper citation: RRID:WB-STRAIN:WBStrain00062572 Copy   

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Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."

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