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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040368
Source Database: WormBase (WB)
Affected Genes: WBGene00001159(eff-1)
Genomic Alteration: WBGene00001159(eff-1)
Availability: available
Source References: EMPTY
Synonyms: eff-1(oj55) II.
Alternate IDs: WB-STRAIN:WH170, CGC_WH170
Notes: Loss of cell fusion in hypodermis (epithelial fusion failures). Viable and fertile as homozygotes. Tail-spike defect in all young larvae, less visible in older larvae and adults. oj55 appears to cause incomplete loss of function, as many cells fuse in postembryonic development. Homozygous males have tail and mating defects. ES-3. Cloned: ORF C26D10.5 encodes a type-I membrane glycoprotein with a single TM domain.
Proper citation: RRID:WB-STRAIN:WBStrain00040368 Copy
http://www.wormbase.org/db/get?name=WBStrain00040367
Source Database: WormBase (WB)
Affected Genes: WBGene00004953(spd-2)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00004953(spd-2), WBGene00006752(unc-13)
Availability: available
Source References: PMID:9649522
Synonyms: nDf29/unc-13(e1091) spd-2(oj29) I.
Alternate IDs: WB-STRAIN:WH163, CGC_WH163
Notes: Heterozygotes are WT and segregate WT, dead eggs and Uncs. At 25C the Unc Spds are Sterile; at 16C the Unc Spds are fertile but produce mostly dead eggs. Unc Spd animals will exhibit a fully penetrant maternal-effect embryonic lethal phenotype if shifted to 25C at the L4 stage. unc-13 spd-2 homozygotes may be propagated at 16C but may become sick causing immense frustration! See also WBPaper00004200.|"Made_by: O'Connell/Maxwell"
Proper citation: RRID:WB-STRAIN:WBStrain00040367 Copy
http://www.wormbase.org/db/get?name=WBStrain00040400
Source Database: WormBase (WB)
Affected Genes: WBGene00001063(dpy-1)|WBGene00015267(chin-1)
Genomic Alteration: WBGene00001063(dpy-1), WBGene00015267(chin-1)
Availability: available
Source References: EMPTY
Synonyms: chin-1(tm1909)/sC1 [dpy-1(s2170) let(gk597)] III.
Alternate IDs: WB-STRAIN:WH515, CGC_WH515
Notes: Maintain under normal conditions. Heterozygotes are WT, and segregate WT, occasional Dpy (non-let recombinant sC1 homozygotes), and nearly sterile tm1909 homozygotes. Pick WT and check for correct segregation of progeny to maintain. Reference: Kumfer et al. (2010) Mol Bio Cell21(2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040400 Copy
http://www.wormbase.org/db/get?name=WBStrain00040330
Source Database: WormBase (WB)
Affected Genes: WBGene00003931(pat-4)
Genomic Alteration: WBGene00003931(pat-4)
Availability: available
Source References: EMPTY
Synonyms: pat-4(st551) III; zpEx204.
Alternate IDs: WB-STRAIN:WB201, CGC_WB201
Notes: zpEx204 [pat-4::YFP + pat-3::CFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. zpEx204 produces a fully functional YFP-tagged pat-4 protein that localizes to the dense bodies in muscle cells, and rescues the lethal phenotype of pat-4(st551) homozygous animals. Reference: Mackinnon AC, et al. Curr Biol. 2002 May 14;12(10):787-97.
Proper citation: RRID:WB-STRAIN:WBStrain00040330 Copy
http://www.wormbase.org/db/get?name=WBStrain00040336
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: wbmEx64.
Alternate IDs: WB-STRAIN:WBM179, CGC_WBM179
Notes: wbmEx64 [rab-3p::nhr-49(cDNA)::unc-54 3'UTR + myo-3p::mCherry::unc54 3'UTR]. mCherry expression in muscle. Pick fluorescent animals to maintain. Reference: Burkewitz K, et al. Cell. 2015 Feb 26; 160(5): 842-55.
Proper citation: RRID:WB-STRAIN:WBStrain00040336 Copy
http://www.wormbase.org/db/get?name=WBStrain00040332
Source Database: WormBase (WB)
Availability: available
Source References: PMID:36653384
Synonyms: uthIs226.
Alternate IDs: WB-STRAIN:WBM55, CGC_WBM55
Notes: Mutagen:Gamma radiation|"uthIs226 [crtc-1p::crtc-1(S76A, S179A)::tdTOMATO::unc-54 3'UTR + rol-6(su1006)]. Rollers. tdTOMATO-tagged, non-phosphorylatable CRTC-1 expression from native promoter. Constitutively nuclear expression in neurons and intestine. Reference: Burkewitz K, et al. Cell. 2015 Feb 26; 160(5): 842-55."
Proper citation: RRID:WB-STRAIN:WBStrain00040332 Copy
http://www.wormbase.org/db/get?name=WBStrain00040342
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: wbmIs66 IV.
Alternate IDs: WB-STRAIN:WBM1141, CGC_WBM1141
Notes: Made_by: Carlos G Silva-Garca|"wbmIs66 [rab-3p::3XFLAG::dpy-10 crRNA::rab-3 3'UTR] (IV:5015000). Superficially wild-type. SKI LODGE system allows for CRISPR knock-in of single-copy transcripts downstream of a tissue-specific promoter. wbmIs66 can be used to direct neuron-specific gene expression from the rab-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific rab-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. G3 (Bethesda). 2019 Jul 9;9(7):2195-2198."|"wbmIs66 [rab-3p::3XFLAG::dpy-10 crRNA::rab-3 3'UTR] (IV:5015000). Superficially wild-type. wbmIs66 can be used to direct neuron-specific gene expression from the rab-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific rab-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. Single-copy Knock-In Loci for Defined Gene Expression in C. elegans. BioRxiv. December 19, 2018 doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00040342 Copy
http://www.wormbase.org/db/get?name=WBStrain00040347
Source Database: WormBase (WB)
Affected Genes: WBGene00001996(hpl-2)
Genomic Alteration: WBGene00001996(hpl-2)
Availability: available
Source References: EMPTY
Synonyms: hpl-2(ok916) III.
Alternate IDs: WB-STRAIN:WFK1, CGC_WFK1
Notes: Made_by: Yogesh Ostwal|"Maintain at 15-20C. Multivulva (Muv) phenotype at higher temperature."
Proper citation: RRID:WB-STRAIN:WBStrain00040347 Copy
http://www.wormbase.org/db/get?name=WBStrain00040349
Source Database: WormBase (WB)
Affected Genes: WBGene00000086(aex-3)|WBGene00000934(dat-1)
Genomic Alteration: WBGene00000086(aex-3), WBGene00000934(dat-1)
Availability: unknown
Source References: EMPTY
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:WG8
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040349 Copy
http://www.wormbase.org/db/get?name=WBStrain00040343
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: wbmIs76 IV.
Alternate IDs: WB-STRAIN:WBM1179, CGC_WBM1179
Notes: Made_by: Carlos G Silva-Garca and Caroline Heintz|"wbmIs76 [eft-3p::3XFLAG::dpy-10 crRNA::unc-54 3'UTR] (IV:5015000). Superficially wild-type. SKI LODGE system allows for CRISPR knock-in of single-copy transcripts downstream of a tissue-specific promoter. wbmIs76 can be used to direct soma-specific gene expression from the eft-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific eft-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. G3 (Bethesda). 2019 Jul 9;9(7):2195-2198."|"wbmIs76 [eft-3p::3XFLAG::dpy-10 crRNA::unc-54 3'UTR] (IV:5015000). Superficially wild-type. wbmIs76 can be used to direct soma-specific gene expression from the eft-3 promoter through CRISPR-mediated insertion of transcripts downstream of tissue-specific eft-3 promoter inserted as a single copy into the C. elegans genome. Reference: Silva-Garca CG, et al. Single-copy Knock-In Loci for Defined Gene Expression in C. elegans. BioRxiv. December 19, 2018 doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00040343 Copy
http://www.wormbase.org/db/get?name=WBStrain00040319
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: vzEx8.
Alternate IDs: WB-STRAIN:VZ55, CGC_VZ55
Notes: vzEx8 [trx-2p(4 kb)::trx-2::GFP + rol-6(su1006)]. Rollers. Pick rollers to maintain. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400.
Proper citation: RRID:WB-STRAIN:WBStrain00040319 Copy
http://www.wormbase.org/db/get?name=WBStrain00040318
Source Database: WormBase (WB)
Affected Genes: WBGene00022663(glrx-21)
Genomic Alteration: WBGene00022663(glrx-21)
Availability: available
Source References: EMPTY
Synonyms: glrx-21(tm2921) III.
Alternate IDs: WB-STRAIN:VZ54, CGC_VZ54
Notes: Made_by: F. Munoz Lobato|"Superficially wild-type. Hypersensitive to selenium-induced motility impairment, but not lethality. Reference: Morgan KL, et al., Toxicol Sci. 2010 Dec;118(2):530-43."
Proper citation: RRID:WB-STRAIN:WBStrain00040318 Copy
http://www.wormbase.org/db/get?name=WBStrain00040394
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:17913784
Synonyms: unc-119(ed3) ojIs58 III.
Alternate IDs: WB-STRAIN:WH416, CGC_WH416
Notes: ojIs58 [pie-1p::sep-1::GFP + unc-119(+)] III. Maintain under normal conditions. Reference: Bembenek J, et al. Development. (2007) 134(21):3837-48.
Proper citation: RRID:WB-STRAIN:WBStrain00040394 Copy
http://www.wormbase.org/db/get?name=WBStrain00040397
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
Source References: EMPTY
Synonyms: sep-1(e2406) I/hT2 (I;III); ojIs58 III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH485, CGC_WH485
Notes: ojIs58 [pie-1p::sep-1::GFP + unc-119(+)] III. Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040397 Copy
http://www.wormbase.org/db/get?name=WBStrain00040396
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
Source References: EMPTY
Synonyms: sep-1(e2406) I/hT2 (I;III); ruIs32 III/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH468, CGC_WH468
Notes: ruIs32 [pie-1p::GFP::H2B + unc-119(+)] III. Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2 [bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040396 Copy
http://www.wormbase.org/db/get?name=WBStrain00040392
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00004775(sep-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00004775(sep-1)
Availability: available
Source References: EMPTY
Synonyms: sep-1(e2406) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WH408, CGC_WH408
Notes: Homozygous embryonic lethal mutation balanced by bli-4- and GFP-marked translocation. Maintain at 15 C. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP e2406 homozygotes (embryonic arrest). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Bembenek J, et al. Curr Biol (2010) Feb 9;20(3):259-64.
Proper citation: RRID:WB-STRAIN:WBStrain00040392 Copy
http://www.wormbase.org/db/get?name=WBStrain00040314
Source Database: WormBase (WB)
Affected Genes: WBGene00007099(trx-2)|WBGene00014028(trxr-2)
Genomic Alteration: WBGene00007099(trx-2), WBGene00014028(trxr-2)
Availability: available
Source References: EMPTY
Synonyms: trxr-2(tm2047) III; trx-2(tm2720) V.
Alternate IDs: WB-STRAIN:VZ17, CGC_VZ17
Notes: Made_by: Briseida Cacho|"Superficially wild-type. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040314 Copy
http://www.wormbase.org/db/get?name=WBStrain00040311
Source Database: WormBase (WB)
Affected Genes: WBGene00007099(trx-2)
Genomic Alteration: WBGene00007099(trx-2)
Availability: available
Source References: EMPTY
Synonyms: trx-2(tm2720) V.
Alternate IDs: WB-STRAIN:VZ13, CGC_VZ13
Notes: Made_by: Briseida Cacho|"Superficially wild-type. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040311 Copy
http://www.wormbase.org/db/get?name=WBStrain00040398
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; ojIs69.
Alternate IDs: WB-STRAIN:WH497, CGC_WH497
Notes: ojIs69 [pie-1::mGFP::chin-1 + unc-119(+)]. N-terminal fusion of mGFP to sole predicted BE0003N10.2 ORF. Reference: Kumfer et al. (2010) Mol Biol Cell (2):266-77.
Proper citation: RRID:WB-STRAIN:WBStrain00040398 Copy
http://www.wormbase.org/db/get?name=WBStrain00040313
Source Database: WormBase (WB)
Affected Genes: WBGene00014028(trxr-2)
Genomic Alteration: WBGene00014028(trxr-2)
Availability: available
Source References: EMPTY
Synonyms: trxr-2(ok2267) III.
Alternate IDs: WB-STRAIN:VZ15, CGC_VZ15
Notes: Made_by: Briseida Cacho|"Superficially wild-type. ok2267 removes bases +114 to 1751 relative to the start of the trxr-2 coding sequence. Reference: Cacho-Valdez B, et al. Antioxid Redox Signal. 2012 Jun 15;16(12):1384-400."
Proper citation: RRID:WB-STRAIN:WBStrain00040313 Copy
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