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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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NOD.129S2(B6)-Il6tm1Kopf/YgchJ Resource Report Resource Website 1+ mentions Issue Issue |
RRID:IMSR_JAX:029264 | Mus musculus | gene symbol note: interleukin 6; mutant strain|congenic strain: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | JAX:029264 | JAX Mice and Services | JAX | sperm | 2026-09-04 09:45:45 | 1 | |||||
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B6NCrl.129P2(B6)-Apoetm1Unc Ccr2 Resource Report Resource Website Issue |
RRID:IMSR_JAX:030896 | Mus musculus | gene symbol note: C-C motif chemokine receptor 2|apolipoprotein E|C-C motif chemokine receptor 5; mutant strain|congenic strain: Ccr2|Apoe|Ccr5 | C-C motif chemokine receptor 2|apolipoprotein E|C-C motif chemokine receptor 5 | targeted mutation 1.1; Bruno Luckow|targeted mutation 1; University of North Carolina|targeted mutation 3.1; Bruno Luckow | JAX:030896 | JAX Mice and Services | JAX | embryo | 2026-09-04 09:45:54 | 0 | |||||
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B6NCrl.129(B6J)-Apoetm1Unc Ccr1 Resource Report Resource Website Issue |
RRID:IMSR_JAX:030892 | Mus musculus | gene symbol note: apolipoprotein E|C-C motif chemokine receptor 1; mutant strain|congenic strain: Apoe|Ccr1 | apolipoprotein E|C-C motif chemokine receptor 1 | targeted mutation 1; University of North Carolina|targeted mutation 1; Ji-Liang Gao | JAX:030892 | JAX Mice and Services | JAX | sperm | 2026-09-04 09:45:54 | 0 | |||||
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B6NCrl.129P2(B6)-Apoetm1Unc Ccr2 Resource Report Resource Website Issue |
RRID:IMSR_JAX:030893 | Mus musculus | gene symbol note: apolipoprotein E|C-C motif chemokine receptor 2; mutant strain|congenic strain: Apoe|Ccr2 | apolipoprotein E|C-C motif chemokine receptor 2 | targeted mutation 1; University of North Carolina|targeted mutation 1.1; Bruno Luckow | JAX:030893 | JAX Mice and Services | JAX | sperm | 2026-09-04 09:45:54 | 0 | |||||
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NOD.Cg-Cd28tm1Mak Cd40tm1Kik Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037143-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| abnormal esophageal epithelium morphology [MP:0000468]| enlarged thymus [MP:0000709]| increased activated T cell number [MP:0001829]| brain inflammation [MP:0001847]| increased T cell derived lymphoma incidence [MP:0002024]| abnormal T cell differentiation [MP:0002145]| abnormal lymphopoiesis [MP:0002401]| decreased immunoglobulin level [MP:0002460]| abnormal cytokine secretion [MP:0003009]| esophageal inflammation [MP:0003278]| insulitis [MP:0004031]| increased length of allograft survival [MP:0004751]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| abnormal class switch recombination [MP:0004816]| abnormal regulatory T cell physiology [MP:0004946]| decreased regulatory T cell number [MP:0004974]| abnormal T cell clonal deletion [MP:0005002]| increased eosinophil cell number [MP:0005011]| increased susceptibility to parasitic infection [MP:0005027]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased cytotoxic T cell cytolysis [MP:0005079]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005465]| abnormal T-helper 1 physiology [MP:0005466]| abnormal T-helper 2 physiology [MP:0005596]| increased susceptibility to type I hypersensitivity reaction [MP:0005671]| abnormal response to transplant [MP:0006413]| increased T cell apoptosis [MP:0008049]| increased memory T cell number [MP:0008074]| increased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008192]| increased CD8-positive [MP:0008482]| alpha-beta T cell number [MP:0008495]| abnormal germinal center B cell physiology [MP:0008496]| decreased spleen germinal center number [MP:0008497]| decreased IgG1 level [MP:0008500]| decreased IgG2a level [MP:0008566]| decreased IgG2b level [MP:0008567]| increased IgG2a level [MP:0008578]| increased interferon-gamma secretion [MP:0008603]| decreased interferon-gamma secretion [MP:0008687]| decreased circulating interferon-gamma level [MP:0008688]| decreased circulating interleukin-4 level [MP:0008699]| increased interleukin-2 secretion [MP:0008700]| decreased interleukin-2 secretion [MP:0008747]| increased interleukin-4 secretion [MP:0009335]| decreased interleukin-4 secretion [MP:0010268]| abnormal T cell anergy [MP:0010766] | Cd28||Ifng||Cd40||| | 037143-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37143-MU, MMRRC_037143, MMRRC_37143 | 2026-09-05 04:09:28 | 1 | ||||
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NOD.Cg-Ifngtm1Ts H2h4 Tg(tetO-Tcra)1Doi/HbmMmmh Resource Report Resource Website Issue |
RRID:MMRRC_037147-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Transgenic ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874] | |Tcra|||Ifng| | 037147-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:22298883 | MMRRC_37147-MU, MMRRC_037147, MMRRC_37147 | 2026-09-05 04:09:28 | 0 | |||
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NOD.Cg-Cd28tm1Mak Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037141-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| abnormal esophageal epithelium morphology [MP:0000468]| enlarged thymus [MP:0000709]| increased activated T cell number [MP:0001829]| brain inflammation [MP:0001847]| increased T cell derived lymphoma incidence [MP:0002024]| abnormal T cell differentiation [MP:0002145]| abnormal lymphopoiesis [MP:0002401]| decreased immunoglobulin level [MP:0002460]| abnormal cytokine secretion [MP:0003009]| esophageal inflammation [MP:0003278]| insulitis [MP:0004031]| increased length of allograft survival [MP:0004751]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| abnormal class switch recombination [MP:0004816]| abnormal regulatory T cell physiology [MP:0004946]| decreased regulatory T cell number [MP:0004974]| abnormal T cell clonal deletion [MP:0005002]| increased eosinophil cell number [MP:0005011]| increased susceptibility to parasitic infection [MP:0005027]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased cytotoxic T cell cytolysis [MP:0005079]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005465]| abnormal T-helper 1 physiology [MP:0005466]| abnormal T-helper 2 physiology [MP:0005596]| increased susceptibility to type I hypersensitivity reaction [MP:0005671]| abnormal response to transplant [MP:0006413]| increased T cell apoptosis [MP:0008049]| increased memory T cell number [MP:0008074]| increased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008192]| increased CD8-positive [MP:0008482]| alpha-beta T cell number [MP:0008495]| abnormal germinal center B cell physiology [MP:0008496]| decreased spleen germinal center number [MP:0008497]| decreased IgG1 level [MP:0008500]| decreased IgG2a level [MP:0008566]| decreased IgG2b level [MP:0008567]| increased IgG2a level [MP:0008578]| increased interferon-gamma secretion [MP:0008603]| decreased interferon-gamma secretion [MP:0008687]| decreased circulating interferon-gamma level [MP:0008688]| decreased circulating interleukin-4 level [MP:0008699]| increased interleukin-2 secretion [MP:0008700]| decreased interleukin-2 secretion [MP:0008747]| increased interleukin-4 secretion [MP:0009335]| decreased interleukin-4 secretion [MP:0010268]| abnormal T cell anergy [MP:0010766] | Cd28||Ifng||| | 037141-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37141-MU, MMRRC_037141, MMRRC_37141 | 2026-09-05 04:09:28 | 1 | ||||
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B6.Cg-B2mtm1Jae Tap1tm1Hpl/Mmucd Resource Report Resource Website Issue |
RRID:MMRRC_032245-UCD | Mus musculus | Research areas: Immunology and Inflammation, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | decreased hematocrit [MP:0000208]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| dermatitis [MP:0001194]| decreased body size [MP:0001265]| reduced long term depression [MP:0001475]| anemia [MP:0001577]| abnormal long term depression [MP:0001898]| abnormal glucose homeostasis [MP:0002078]| abnormal T cell differentiation [MP:0002145]| abnormal lymph node morphology [MP:0002339]| abnormal double-positive T cell morphology [MP:0002408]| abnormal CD8-positive [MP:0002436]| alpha-beta cytotoxic T cell morphology [MP:0002461]| increased immunoglobulin level [MP:0002493]| increased IgG level [MP:0002494]| increased IgM level [MP:0002722]| abnormal immune system organ morphology [MP:0003008]| enhanced long term potentiation [MP:0003306]| small intestinal inflammation [MP:0003944]| abnormal T cell subpopulation ratio [MP:0004165]| abnormal lateral geniculate nucleus morphology [MP:0004753]| abnormal miniature excitatory postsynaptic currents [MP:0004792]| abnormal synaptic vesicle number [MP:0005026]| decreased susceptibility to parasitic infection [MP:0005078]| abnormal cytotoxic T cell physiology [MP:0005348]| increased T cell proliferation [MP:0005638]| hemochromatosis [MP:0008071]| absent B cells [MP:0008074]| increased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008077]| decreased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008079]| abnormal CD8-positive [MP:0008080]| alpha-beta T cell number [MP:0008097]| increased CD8-positive [MP:0008101]| alpha-beta T cell number [MP:0008346]| decreased CD8-positive [MP:0008350]| alpha-beta T cell number [MP:0008535]| abnormal CD8-positive [MP:0008560]| alpha-beta T cell differentiation [MP:0008571]| increased plasma cell number [MP:0008696]| lymph node hypoplasia [MP:0008700]| increased gamma-delta T cell number [MP:0008751]| increased gamma-delta intraepithelial T cell number [MP:0008752]| enlarged lateral ventricles [MP:0009538]| reduced long term depression [MP:0001475]| abnormal long term depression [MP:0001898]| increased tumor incidence [MP:0002020]| enhanced long term potentiation [MP:0003008]| abnormal lateral geniculate nucleus morphology [MP:0004165]| abnormal miniature excitatory postsynaptic currents [MP:0004753]| abnormal synaptic vesicle number [MP:0004792]| increased lung tumor incidence [MP:0008014]| enlarged lateral ventricles [MP:0008535]| abnormal synaptic bouton morphology [MP:0008571]| increased uterus tumor incidence [MP:0009222]| abnormal synapse morphology [MP:0009538]| increased gastrointestinal tumor incidence [MP:0010279]| increased mammary gland tumor incidence [MP:0010299]| increased skin tumor incidence [MP:0010300] | |B2m||Tap1 | 032245-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11118151 PMID:17420446 PMID:9548460 PMID:2685607 PMID:8643655 |
MMRRC_32245-UCD, MMRRC_032245, MMRRC_32245 | 2026-09-05 04:08:50 | 0 | |||
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B6.Cg-Tg(Nes-cre)1Kln/MullMmmh Resource Report Resource Website Issue |
RRID:MMRRC_031750-MU | Mus musculus | Research areas: ; Mutation Type: Transgenic ; Collection: Neuroscience Blueprint | Nes|cre| | 031750-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_31750-MU, MMRRC_031750, MMRRC_3175 | 2026-09-05 04:08:47 | 0 | |||||
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B6J.Cg-Apoetm1Unc Tg(MSR1-Plau)1Ddi/Mmmh Resource Report Resource Website Issue |
RRID:MMRRC_067987-MU | Mus musculus | Research areas: Cardiovascular, Models for Human Disease; Mutation Type: Transgenic ; Collection: | abnormal cochlea morphology [MP:0000031]| organ of Corti degeneration [MP:0000043]| abnormal stria vascularis morphology [MP:0000048]| increased bone mineral density [MP:0000062]| decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| abnormal vertebrae morphology [MP:0000137]| abnormal circulating cholesterol level [MP:0000180]| increased circulating LDL cholesterol level [MP:0000182]| decreased circulating HDL cholesterol level [MP:0000186]| decreased hematocrit [MP:0000208]| increased monocyte cell number [MP:0000220]| decreased monocyte cell number [MP:0000223]| hypertension [MP:0000231]| abnormal blood flow velocity [MP:0000233]| macrocytosis [MP:0000248]| abnormal blood vessel physiology [MP:0000249]| echinocytosis [MP:0000256]| abnormal heart morphology [MP:0000266]| abnormal aorta morphology [MP:0000272]| enlarged heart [MP:0000274]| altered response to myocardial infarction [MP:0000343]| decreased hair follicle number [MP:0000379]| alopecia [MP:0000414]| sparse hair [MP:0000416]| abnormal femur morphology [MP:0000559]| abnormal liver morphology [MP:0000598]| amyloidosis [MP:0000604]| abnormal liver physiology [MP:0000609]| abnormal adrenal gland morphology [MP:0000639]| abnormal immune system morphology [MP:0000685]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| enlarged thymus [MP:0000709]| abnormal skin condition [MP:0001191]| thick skin [MP:0001200]| skin lesions [MP:0001212]| hyperkeratosis [MP:0001242]| abnormal dermal layer morphology [MP:0001243]| thick dermal layer [MP:0001245]| mixed cellular infiltration to dermis [MP:0001246]| decreased body length [MP:0001258]| increased body weight [MP:0001260]| obese [MP:0001261]| decreased body weight [MP:0001262]| abnormal retina morphology [MP:0001325]| dry eyes [MP:0001337]| Meibomian gland atrophy [MP:0001345]| increased anxiety-related response [MP:0001363]| abnormal stationary movement [MP:0001388]| abnormal locomotor behavior [MP:0001392]| abnormal response to new environment [MP:0001413]| decreased exploration in new environment [MP:0001417]| abnormal spatial learning [MP:0001463]| increased startle reflex [MP:0001488]| decreased startle reflex [MP:0001489]| abnormal kindling response [MP:0001499]| abnormal coat appearance [MP:0001510]| abnormal skeleton physiology [MP:0001533]| abnormal hematopoietic system physiology [MP:0001545]| abnormal lipid level [MP:0001547]| hyperlipidemia [MP:0001548]| increased circulating triglyceride level [MP:0001552]| increased circulating free fatty acid level [MP:0001554]| increased circulating HDL cholesterol level [MP:0001556]| hyperglycemia [MP:0001559]| anemia [MP:0001577]| cardiac hypertrophy [MP:0001625]| hypersecretion of corticosterone [MP:0001744]| increased circulating corticosterone level [MP:0001745]| abnormal immune system physiology [MP:0001790]| impaired macrophage phagocytosis [MP:0001798]| abnormal inflammatory response [MP:0001845]| heart inflammation [MP:0001853]| kidney inflammation [MP:0001859]| lung inflammation [MP:0001861]| vascular inflammation [MP:0001863]| abnormal lung volume [MP:0001942]| deafness [MP:0001967]| abnormal skin morphology [MP:0002060]| abnormal fear/anxiety-related behavior [MP:0002065]| increased circulating insulin level [MP:0002079]| premature death [MP:0002083]| abnormal lipid homeostasis [MP:0002118]| abnormal cardiovascular system morphology [MP:0002127]| abnormal kidney morphology [MP:0002135]| abnormal brain morphology [MP:0002152]| abnormal gland physiology [MP:0002164]| gliosis [MP:0002183]| abnormal artery morphology [MP:0002191]| neurodegeneration [MP:0002229]| abnormal pulmonary alveolus morphology [MP:0002270]| abnormal lymph node morphology [MP:0002339]| abnormal dendritic cell physiology [MP:0002376]| abnormal cell-mediated immunity [MP:0002421]| abnormal macrophage morphology [MP:0002446]| abnormal erythrocyte morphology [MP:0002447]| abnormal macrophage physiology [MP:0002451]| increased immunoglobulin level [MP:0002461]| abnormal neutrophil physiology [MP:0002463]| increased IgG level [MP:0002493]| increased IgM level [MP:0002494]| abnormal blood coagulation [MP:0002551]| hepatic steatosis [MP:0002628]| reticulocytosis [MP:0002640]| poikilocytosis [MP:0002643]| decreased circulating triglyceride level [MP:0002644]| abnormal sciatic nerve morphology [MP:0002651]| abnormal immune serum protein physiology [MP:0002723]| decreased circulating insulin level [MP:0002727]| abnormal thermal nociception [MP:0002733]| glomerulonephritis [MP:0002743]| dilated heart left ventricle [MP:0002753]| decreased vertical activity [MP:0002757]| abnormal retinal vasculature morphology [MP:0002792]| increased thigmotaxis [MP:0002797]| increased heart weight [MP:0002833]| increased systemic arterial blood pressure [MP:0002842]| decreased systemic arterial blood pressure [MP:0002843]| cochlear ganglion degeneration [MP:0002857]| increased growth rate [MP:0002865]| albuminuria [MP:0002871]| decreased hemoglobin content [MP:0002874]| increased insulin sensitivity [MP:0002891]| thick ventricular wall [MP:0002953]| increased urine protein level [MP:0002962]| increased liver weight [MP:0002981]| abnormal cytokine secretion [MP:0003009]| increased vasoconstriction [MP:0003025]| decreased myocardial infarction size [MP:0003038]| abnormal impulse conducting system conduction [MP:0003137]| cardiac fibrosis [MP:0003141]| abnormal tectorial membrane morphology [MP:0003149]| impaired muscle relaxation [MP:0003157]| increased cholesterol efflux [MP:0003192]| amyloid beta deposits [MP:0003329]| hypopituitarism [MP:0003348]| increased cardiac output [MP:0003394]| abnormal nervous system physiology [MP:0003633]| abnormal response/metabolism to endogenous compounds [MP:0003638]| abnormal axon extension [MP:0003651]| oxidative stress [MP:0003674]| xanthoma [MP:0003692]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal retinal inner nuclear layer morphology [MP:0003733]| abnormal bone structure [MP:0003795]| impaired macrophage chemotaxis [MP:0003799]| vascular smooth muscle hypoplasia [MP:0003814]| enhanced coordination [MP:0003858]| abnormal myelin sheath morphology [MP:0003871]| decreased macrophage cell number [MP:0003884]| abnormal ST segment [MP:0003897]| decreased kidney weight [MP:0003918]| abnormal lymphocyte physiology [MP:0003945]| abnormal cholesterol level [MP:0003947]| abnormal circulating lipid level [MP:0003949]| increased circulating VLDL triglyceride level [MP:0003975]| increased circulating phospholipid level [MP:0003980]| increased cholesterol level [MP:0003982]| decreased cholesterol level [MP:0003983]| arteriosclerosis [MP:0003991]| aortic dissection [MP:0004044]| abnormal coronary artery morphology [MP:0004111]| abnormal aortic arch morphology [MP:0004113]| increased compact bone thickness [MP:0004148]| increased renal tubule apoptosis [MP:0004153]| abnormal basilar membrane morphology [MP:0004308]| cochlear inner hair cell degeneration [MP:0004398]| cochlear outer hair cell degeneration [MP:0004404]| abnormal spiral modiolar artery morphology [MP:0004629]| spiral modiolar artery stenosis [MP:0004630]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal synaptic vesicle morphology [MP:0004769]| increased macrophage derived foam cell number [MP:0004778]| increased anti-nuclear antigen antibody level [MP:0004794]| increased susceptibility to systemic lupus erythematosus [MP:0004801]| increased mean systemic arterial blood pressure [MP:0004875]| decreased systemic vascular resistance [MP:0004879]| abnormal vascular wound healing [MP:0004883]| decreased adiponectin level [MP:0004893]| increased uterus weight [MP:0004904]| skin inflammation [MP:0004947]| increased spleen weight [MP:0004952]| abnormal osteoblast physiology [MP:0005006]| increased B cell number [MP:0005014]| increased T cell number [MP:0005015]| decreased T cell number [MP:0005018]| increased susceptibility to parasitic infection [MP:0005027]| abnormal thrombosis [MP:0005048]| decreased acute inflammation [MP:0005087]| decreased cardiac muscle contractility [MP:0005140]| increased circulating VLDL cholesterol level [MP:0005145]| decreased circulating VLDL cholesterol level [MP:0005146]| abnormal blood-brain barrier function [MP:0005167]| increased circulating cholesterol level [MP:0005178]| decreased circulating cholesterol level [MP:0005179]| glomerulosclerosis [MP:0005264]| abnormal cholesterol homeostasis [MP:0005278]| improved glucose tolerance [MP:0005292]| impaired glucose tolerance [MP:0005293]| abnormal circulating amino acid level [MP:0005311]| increased triglyceride level [MP:0005317]| abnormal enzyme/coenzyme level [MP:0005319]| abnormal renal glomerulus morphology [MP:0005325]| insulin resistance [MP:0005331]| abnormal gonadal fat pad morphology [MP:0005335]| atherosclerotic lesions [MP:0005338]| increased susceptibility to atherosclerosis [MP:0005339]| altered susceptibility to atherosclerosis [MP:0005340]| decreased susceptibility to atherosclerosis [MP:0005341]| abnormal bile salt homeostasis [MP:0005365]| vascular stenosis [MP:0005412]| abnormal circulating protein level [MP:0005416]| increased macrophage cell number [MP:0005425]| increased susceptibility to weight gain [MP:0005455]| vascular smooth muscle hyperplasia [MP:0005489]| abnormal eye electrophysiology [MP:0005551]| increased circulating creatinine level [MP:0005553]| increased circulating glucose level [MP:0005559]| decreased circulating glucose level [MP:0005560]| abnormal enzyme/coenzyme activity [MP:0005584]| increased vasodilation [MP:0005590]| decreased vasodilation [MP:0005591]| abnormal vascular smooth muscle morphology [MP:0005592]| abnormal vascular smooth muscle physiology [MP:0005595]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| decreased susceptibility to diet-induced obesity [MP:0005659]| decreased circulating leptin level [MP:0005668]| increased circulating leptin level [MP:0005669]| increased apoptosis [MP:0006042]| abnormal vascular endothelial cell morphology [MP:0006055]| decreased cerebral infarction size [MP:0006058]| increased cerebral infarction size [MP:0006060]| abnormal circulating homocysteine level [MP:0006076]| increased fat cell size [MP:0006094]| calcified artery [MP:0006133]| artery occlusion [MP:0006134]| increased systemic arterial systolic blood pressure [MP:0006144]| decreased systemic arterial systolic blood pressure [MP:0006264]| aortic aneurysm [MP:0006278]| abnormal T cell number [MP:0006387]| delayed cellular replicative senescence [MP:0008009]| impaired lipolysis [MP:0008033]| abnormal CD4-positive [MP:0008073]| alpha beta T cell number [MP:0008074]| increased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| decreased CD4-positive [MP:0008090]| alpha beta T cell number [MP:0008143]| decreased CD8-positive [MP:0008174]| alpha-beta T cell number [MP:0008181]| increased T-helper 2 cell number [MP:0008182]| abnormal dendrite morphology [MP:0008217]| decreased follicular B cell number [MP:0008243]| increased marginal zone B cell number [MP:0008248]| decreased marginal zone B cell number [MP:0008288]| abnormal B cell activation [MP:0008289]| abnormal macrophage derived foam cell morphology [MP:0008389]| abnormal mononuclear phagocyte morphology [MP:0008406]| abnormal adrenal cortex morphology [MP:0008428]| abnormal adrenal medulla morphology [MP:0008511]| hypochromic macrocytic anemia [MP:0008515]| increased cellular sensitivity to hydrogen peroxide [MP:0008544]| abnormal spatial working memory [MP:0008553]| thin retinal inner nuclear layer [MP:0008561]| thin retinal outer nuclear layer [MP:0008566]| impaired olfaction [MP:0008567]| increased circulating tumor necrosis factor level [MP:0008577]| decreased tumor necrosis factor secretion [MP:0008596]| increased interferon-gamma secretion [MP:0008597]| decreased interferon-gamma secretion [MP:0008617]| increased circulating interferon-gamma level [MP:0008660]| increased circulating interleukin-6 level [MP:0008817]| decreased circulating interleukin-6 level [MP:0008916]| increased circulating interleukin-12 level [MP:0009278]| increased interleukin-10 secretion [MP:0009289]| hematoma [MP:0009346]| abnormal astrocyte physiology [MP:0009538]| abnormal bone marrow cell physiology [MP:0009763]| decreased epididymal fat pad weight [MP:0009764]| decreased trabecular bone thickness [MP:0009814]| abnormal synapse morphology [MP:0009862]| increased sensitivity to induced morbidity/mortality [MP:0009864]| decreased sensitivity to induced morbidity/mortality [MP:0009866]| increased prostaglandin level [MP:0009868]| abnormal aorta elastic tissue morphology [MP:0009873]| abnormal aorta endothelium morphology [MP:0009932]| abnormal aorta wall morphology [MP:0010210]| abnormal descending thoracic aorta morphology [MP:0010451]| abnormal aorta tunica media morphology [MP:0010483]| skin fibrosis [MP:0010574]| abnormal circulating cytokine level [MP:0010658]| kidney microaneurysm [MP:0010659]| aortic sinus aneurysm [MP:0010663]| aorta dilation [MP:0010724]| thoracic aorta aneurysm [MP:0010760]| abdominal aorta aneurysm [MP:0010868]| abnormal brachiocephalic trunk morphology [MP:0010869]| thick interventricular septum [MP:0010879]| abnormal macrophage chemotaxis [MP:0010895]| increased bone trabecula number [MP:0010922]| decreased bone trabecula number [MP:0010933]| decreased trabecular bone volume [MP:0010935]| increased lung compliance [MP:0010950]| alveolitis [MP:0011086]| decreased trabecular bone connectivity density [MP:0011231]| increased airway resistance [MP:0011294]| abnormal lung hysteresivity [MP:0011309]| postnatal lethality [MP:0011339]| incomplete penetrance [MP:0011353]| abnormal vitamin E level [MP:0011368]| renal glomerulus hypertrophy [MP:0011430]| abnormal kidney arterial blood vessel morphology [MP:0011477]| abnormal glomerular mesangium morphology [MP:0011508]| expanded mesangial matrix [MP:0011509]| increased kidney apoptosis [MP:0011561]| mesangiolysis [MP:0011567]| abnormal urine nucleoside level [MP:0011572]| glomerular capillary thrombosis [MP:0011578]| dilated glomerular capillary [MP:0011581]| renal glomerulus lipidosis [MP:0011599]| increased renal glomerulus lobularity [MP:0011939]| abnormal aorta bulb morphology [MP:0011941]| increased lipoprotein lipase activity [MP:0011951]| increased triglyceride lipase activity [MP:0011967]| increased phosphatidylcholine-sterol O-acyltransferase activity [MP:0012307]| increased food intake [MP:0012335]| increased fluid intake [MP:0013022]| increased cardiac stroke volume [MP:0014169]| increased or absent threshold for auditory brainstem response [MP:0020253]| impaired spatial learning [MP:0020408]| increased circulating homocysteine level [MP:0020519] | Plau||MSR1||Apoe | 067987-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:15096455 PMID:15297377 PMID:16554301 PMID:27262672 PMID:23536772 PMID:20380835 |
MMRRC_67987-MU, MMRRC_067987, MMRRC_67987 | 2026-09-05 04:15:46 | 0 | |||
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STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax Resource Report Resource Website Issue |
RRID:MMRRC_069611-JAX | Mus musculus | Research areas: Metabolism, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| abnormal eating behavior [MP:0001431]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| decreased insulin secretion [MP:0003059]| increased circulating glycerol level [MP:0003443]| increased circulating cholesterol level [MP:0005178]| decreased oxygen consumption [MP:0005290]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| abnormal triiodothyronine level [MP:0005472]| increased circulating thyroxine level [MP:0005477]| increased circulating triiodothyronine level [MP:0005480]| increased body temperature [MP:0005533]| decreased brown fat cell lipid droplet size [MP:0009125]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| impaired adaptive thermogenesis [MP:0011049]| decreased brown adipose tissue mass [MP:0014169] | |Gpd2||Slc25a13 | 069611-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:17591776 PMID:14701727 |
MMRRC_69611-JAX, MMRRC_069611, MMRRC_69611 | 2026-09-05 04:15:53 | 0 | |||
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C.129-Slc25a13tm1Lct/SinaMmjax Resource Report Resource Website Issue |
RRID:MMRRC_069594-JAX | Mus musculus | Research areas: Metabolism; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643] | Slc25a13 | 069594-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14701727 | MMRRC_69594-JAX, MMRRC_069594, MMRRC_69594 | 2026-09-05 04:15:53 | 0 | |||
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C.129(ICR)-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:581 | Mus musculus |
C.129S4(Cg)-Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:581 | Center for Animal Resources and Development | CARD | embryo | 2026-09-04 10:23:38 | 0 | ||||
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NZB;129(ICR)(C)(NZW)-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:582 | Mus musculus |
STOCK Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:582 | Center for Animal Resources and Development | CARD | embryo | 2026-09-04 10:23:38 | 0 | ||||
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B6;129(ICR)-Parp1tm1Hsmm Tg(GPT-delta)/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:585 | Mus musculus |
STOCK Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | transgene; National Cancer Center Research Institute|targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:585 | Center for Animal Resources and Development | CARD | embryo | 2026-09-04 10:23:38 | 0 | ||||
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D2;129-Parp1tm1Hsmm/Hsmm Resource Report Resource Website Issue |
RRID:IMSR_CARD:584 | Mus musculus |
D2;129S4-Parp1 |
gene symbol note: poly (ADP-ribose) polymerase family; member 1; mutant stock: Parp1 | poly (ADP-ribose) polymerase family; member 1 | targeted mutation 1; Hiroshi Suzuki Mitsuko Masutani | CARD:584 | Center for Animal Resources and Development | CARD | embryo | 2026-09-04 10:23:38 | 0 | ||||
|
B6;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04918 | Mus musculus | gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04918 | RIKEN BioResource Research Center | RBRC | embryo | 2026-09-04 10:24:30 | 0 | |||||
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C;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04919 | Mus musculus |
C.129S2-Il6 |
gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04919 | RIKEN BioResource Research Center | RBRC | sperm | 2026-09-04 10:24:30 | 0 | ||||
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B6.Cg-Ighmtm1Cgn Tg(Aicda-cre)9Mbu Gt(ROSA)26Sor Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC05550 | Mus musculus |
B6.Cg-Gt(ROSA)26Sor |
gene symbol note: |transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano; mutant stock: |Tg(Aicda-cre)9Mbu|Ighm|Aicda|Gt(ROSA)26Sor | |transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano | |transgene insertion 9; Meinrad Busslinger|targeted mutation 1; University of Cologne|activation-induced cytidine deaminase|targeted mutation 1; Stuart Orkin | RBRC05550 | RIKEN BioResource Research Center | RBRC | embryo | 2026-09-04 10:24:36 | 0 | ||||
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MSM.MRL-Faslpr/OhnotRbrc Resource Report Resource Website Issue |
RRID:IMSR_RBRC06798 | Mus musculus | gene symbol note: Fas cell surface death receptor; mutant strain: Fas | Fas cell surface death receptor | lymphoproliferation | RBRC06798 | RIKEN BioResource Research Center | RBRC | embryo | 2026-09-04 10:24:45 | 0 |
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