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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ESTHER
 
Resource Report
Resource Website
100+ mentions
ESTHER (RRID:SCR_002621) ESTHER data or information resource, database Database and tools for analysis of protein and nucleic acid sequences belonging to superfamily of alpha/beta hydrolases homologous to cholinesterases. Covers multiple species, including human, mouse caenorhabditis and drosophila., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. alpha hydrolase, beta hydrolase, cholinesterase, protein, protein superfamily, blast, gene, protein binding, protein-protein interaction, nucleotide, nucleotide sequence, enzyme, genetics, genome, genomics, mutation, disease, gene expression, peptide, chromosome is listed by: re3data.org
is related to: UniProtKB
is related to: AceDB
has parent organization: INRA - French National Institute for Agricultural Research; Paris; France
PMID:23193256 Free, Available for download, Freely available nif-0000-30526, SCR_008479, nif-0000-02817, r3d100010542 https://doi.org/10.17616/R33K77 SCR_002621 ESTerases and alpha/beta-Hydrolase Enzymes and Relatives, ESTHER Database, ESTerases and alpha / beta-hydrolase Enzymes and Relatives 2026-09-02 05:39:00 134
RNA Abundance Database
 
Resource Report
Resource Website
1+ mentions
RNA Abundance Database (RRID:SCR_002771) RAD data or information resource, data repository, database, resource, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE, Documented on March 24, 2014. A resource for gene expression studies, storing highly curated MIAME-compliant studies (i.e. experiments) employing a variety of technologies such as filter arrays, 2-channel microarrays, Affymetrix chips, SAGE, MPSS and RT-PCR. Data were available for querying and downloading based on the MGED ontology, publications or genes. Both public and private studies (the latter viewable only by users having appropriate logins and permissions) were available from this website. Specific details on protocols, biomaterials, study designs, etc., are collected through a user-friendly suite of web annotation forms. Software has been developed to generate MAGE-ML documents to enable easy export of studies stored in RAD to any other database accepting data in this format. RAD is part of a more general Genomics Unified Schema (http://gusdb.org), which includes a richly annotated gene index (http://allgenes.org), thus providing a platform that integrates genomic and transcriptomic data from multiple organisms. NOTE: Due to changes in technology and funding, the RAD website is no longer available. RAD as a schema is still very much active and incorporated in the GUS (Genomics Unified Schema) database system used by CBIL (EuPathDB, Beta Cell Genomics) and others. The schema for RAD can be viewed along with the other GUS namespaces through our Schema Browser. gene expression, gene, affymetrix, biomaterial, genomics, microarray, mpss, ontology, rna, rt-pcr, sage, functional genomics, transcript abundance is listed by: OMICtools
is related to: MIAME
is related to: MGED Ontology
is related to: MicroArray and Gene Expression Markup Language
has parent organization: University of Pennsylvania; Philadelphia; USA
NIH ;
NHGRI RO1-HG-01539;
NIDDK U01DK56947;
NHGRI K25-HG-02296;
NHGRI K25-HG-00052
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00869, nif-0000-00133, r3d100000017 https://doi.org/10.17616/R3QP4Q SCR_002771 RNA Abundance Database 2026-09-02 05:39:03 4
New Science of Addiction: Genetics and the Brain
 
Resource Report
Resource Website
1+ mentions
New Science of Addiction: Genetics and the Brain (RRID:SCR_002770) New Science of Addiction data or information resource, disease-related portal, narrative resource, portal, topical portal, training material A physiologic and molecular look at drug addiction involving many factors including: basic neurobiology, a scientific examination of drug action in the brain, the role of genetics in addiction, and ethical considerations. Designed to be used by students, teachers and members of the public, the materials meet selected US education standards for science and health. Drug addiction is a chronic disease characterized by changes in the brain which result in a compulsive desire to use a drug. A combination of many factors including genetics, environment and behavior influence a person's addiction risk, making it an incredibly complicated disease. The new science of addiction considers all of these factors - from biology to family - to unravel the complexities of the addicted brain. * Natural Reward Pathways Exist in the Brain: The reward pathway is responsible for driving our feelings of motivation, reward and behavior. * Drugs Alter the Brain's Reward Pathway: Drugs work over time to change the reward pathway and affect the entire brain, resulting in addiction. * Genetics Is An Important Factor In Addiction: Genetic susceptibility to addiction is the result of the interaction of many genes. * Timing and Circumstances Influence Addiction: If you use drugs when you are an adolescent, you are more likely to develop lifetime addiction. An individual's social environment also influences addiction risk. * Challenges and Issues in Addiction: Addiction impacts society with many ethical, legal and social issues. drug abuse, drug delivery, drug, drug of abuse, environmental risk factor, genetic factor, genetics, addiction, gene, treatment, brain, brain circuit, pathway, human, lesson plan, neuron, reward pathway, spanish, teacher, chronic disease has parent organization: University of Utah Genetic Science Learning Center - Learn Genetics Substance-Related Disorder NIDA 1 R25 DA 15461 Free nif-0000-00430 SCR_002770 2026-09-02 05:39:04 3
Aging Genes and Interventions Database
 
Resource Report
Resource Website
1+ mentions
Aging Genes and Interventions Database (RRID:SCR_002701) AGEID data or information resource, data repository, database, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 17,2023. A database of genes and interventions connected with aging phenotypes including those with respect to their effects on life-span or age-related neurological diseases. Information includes: organism, aging phenotype, allele type, strain, gene function, phenotypes, mutant, and homologs. If you know of published data (or your own unpublished data that you'd like to share) not currently in the database, please use the Submit a Gene/Intervention link. allele, strain, gene function, phenotype, mutant, homolog, mutation, degeneration, gene, intervention, life-span is used by: Aging Portal
is used by: NIF Data Federation
has parent organization: University of Washington; Seattle; USA
Aging, Age-related neurological disease, Neurological disease Ellison Medical Foundation PMID:12044961 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-23326 http://sageke.sciencemag.org/highlights/gidb/ SCR_002701 Aging Genes DB, Aging Genes Database, Genes/Interventions Database 2026-09-02 05:38:55 2
FlyMine
 
Resource Report
Resource Website
100+ mentions
FlyMine (RRID:SCR_002694) FlyMine data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. Integrated database of genomic, expression and protein data for Drosophila, Anopheles, C. elegans and other organisms. You can run flexible queries, export results and analyze lists of data. FlyMine presents data in categories, with each providing information on a particular type of data (for example Gene Expression or Protein Interactions). Template queries, as well as the QueryBuilder itself, allow you to perform searches that span data from more than one category. Advanced users can use a flexible query interface to construct their own data mining queries across the multiple integrated data sources, to modify existing template queries or to create your own template queries. Access our FlyMine data via our Application Programming Interface (API). We provide client libraries in the following languages: Perl, Python, Ruby and & Java API anopheles, genome, c. elegans, drosophila, gene, chromosomal location, genomics, proteomics, gene expression, interaction, homology, function, regulation, protein, phenotype, pathway, disease, publication, FASEB list is related to: FlyBase
is related to: UniProt
is related to: Ensembl
is related to: InterPro
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: Tree families database
is related to: IntAct
is related to: Gene Ontology
is related to: GOA
is related to: ArrayExpress
is related to: REDfly Regulatory Element Database for Drosophilia
is related to: KEGG
is related to: Reactome
has parent organization: University of Cambridge; Cambridge; United Kingdom
Wellcome Trust 067205;
NHGRI
PMID:17615057 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02845 SCR_002694 2026-09-02 05:38:55 107
PharmGKB
 
Resource Report
Resource Website
1000+ mentions
PharmGKB (RRID:SCR_002689) PharmGKB data access protocol, data or information resource, data repository, data set, database, service resource, software resource, storage service resource, web service Database and central repository for genetic, genomic, molecular and cellular phenotype data and clinical information about people who have participated in pharmacogenomics research studies. The data includes, but is not limited to, clinical and basic pharmacokinetic and pharmacogenomic research in the cardiovascular, pulmonary, cancer, pathways, metabolic and transporter domains. PharmGKB welcomes submissions of primary data from all research into genes and genetic variation and their effects on drug and disease phenotypes. PharmGKB collects, encodes, and disseminates knowledge about the impact of human genetic variations on drug response. They curate primary genotype and phenotype data, annotate gene variants and gene-drug-disease relationships via literature review, and summarize important PGx genes and drug pathways. PharmGKB is part of the NIH Pharmacogenomics Research Network (PGRN), a nationwide collaborative research consortium. Its aim is to aid researchers in understanding how genetic variation among individuals contributes to differences in reactions to drugs. A selected subset of data from PharmGKB is accessible via a SOAP interface. Downloaded data is available for individual research purposes only. Drugs with pharmacogenomic information in the context of FDA-approved drug labels are cataloged and drugs with mounting pharmacogenomic evidence are listed. pharmacogenomics, microarray, pathway, phenotype, snp array, genotype, clinical, genetic variation, drug, gene, genetic variation, disease, cardiovascular, pulmonary, cancer, metabolic, transporter, drug response, small molecule, research, drug response, FASEB list is used by: NIF Data Federation
is listed by: OMICtools
is related to: WikiPathways
is related to: ConsensusPathDB
is related to: Integrated Molecular Interaction Database
is related to: MalaCards
is related to: phenomeNET
has parent organization: Stanford University; Stanford; California
is parent organization of: PharmGKB Ontology
NIGMS R24 GM61374 PMID:11908751 Free, Freely available nif-0000-00414, OMICS_01586, r3d100012325 https://doi.org/10.17616/R31H1N SCR_002689 Pharmacogenomics Knowledge Base 2026-09-02 05:39:01 1276
Gene Ontology
 
Resource Report
Resource Website
10000+ mentions
Gene Ontology (RRID:SCR_002811) GO consortium, data or information resource, knowledge environment resource, organization portal, portal, project portal Computable knowledge regarding functions of genes and gene products. GO resources include biomedical ontologies that cover molecular domains of all life forms as well as extensive compilations of gene product annotations to these ontologies that provide largely species-neutral, comprehensive statements about what gene products do. Used to standardize representation of gene and gene product attributes across species and databases. gene, product, annotation, molecular, function, cellular, biological, role, database, query, obo, gold standard, bio.tools, FASEB list is used by: NIF Data Federation
is used by: GreenPhylDB
is used by: LIPID MAPS Proteome Database
is used by: Aging Portal
is used by: ChannelPedia
is used by: Open PHACTS
is used by: CoPub
is used by: PhenoGO
is used by: Database for Annotation Visualization and Integrated Discovery
is used by: MitoMiner
is used by: dcGO
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is used by: barleyGO
is used by: SynGO
is used by: Functional Annotation
is used by: SwissLipids
is listed by: BioPortal
is listed by: OBO
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is affiliated with: Mouse Genome Informatics: The Gene Ontology Project
is related to: GenNav
is related to: SynaptomeDB
is related to: High-Throughput GoMiner
is related to: Onto-Design
is related to: OnEx - Ontology Evolution Explorer
is related to: Avadis
is related to: GONUTS
is related to: PiNGO
is related to: Automated Microarray Pipeline
is related to: categoryCompare
is related to: globaltest
is related to: Semantic Measures Library
is related to: WegoLoc
is related to: AnimalTFDB
is related to: MEME Suite - Motif-based sequence analysis tools
is related to: Arabidopsis Hormone Database
is related to: DAVID
is related to: Arabidopsis thaliana Protein Interactome Database
is related to: TM4 Microarray Software Suite - TIGR MultiExperiment Viewer
is related to: pSTIING
is related to: GoMiner
is related to: FunSimMat
is related to: GeneSpeed- A Database of Unigene Domain Organization
is related to: Centre for Modeling Human Disease Gene Trap Resource
is related to: Patterns of Gene Expression in Drosophila Embryogenesis
is related to: Babelomics
is related to: BioPerl
is related to: GeneCruiser
is related to: GOLEM An interactive, graphical gene-ontology visualization, navigation, and analysis tool
is related to: GOToolBox Functional Investigation of Gene Datasets
is related to: Cotton EST Database
is related to: MouseNET
is related to: PLANTTFDB
is related to: T-profiler
is related to: Physico-Chemical Process
is related to: Integrated Molecular Interaction Database
is related to: SEGS
is related to: GOCat
is related to: Quantitative Enrichment of Sequence Tags
is related to: Neural-Immune Gene Ontology
is related to: INMEX
is related to: StRAnGER
is related to: QuickGO
is related to: Repository of molecular brain neoplasia data
is related to: Cardiovascular Gene Ontology Annotation Initiative
is related to: PANTHER
is related to: Short Time-series Expression Miner (STEM)
is related to: DATFAP
is related to: GORetriever
is related to: Gene Ontology Browsing Utility (GOBU)
is related to: GeneTools
is related to: GOSlimViewer
is related to: go-moose
is related to: Network Ontology Analysis
is related to: Onto-Compare
is related to: Onto-Express
is related to: OntoVisT
is related to: STRAP
is related to: CGAP GO Browser
is related to: COBrA
is related to: Gene Class Expression
is related to: GeneInfoViz
is related to: GOfetcher
is related to: GoFish
is related to: GOProfiler
is related to: GOanna
is related to: Manatee
is related to: Pandora - Protein ANnotation Diagram ORiented Analysis
is related to: TAIR Keyword Browser
is related to: Wandora
is related to: GOTaxExplorer
is related to: Onto-Miner
is related to: Onto-Translate
is related to: ToppGene Suite
is related to: DBD - Slim Gene Ontology
is related to: ONTO-PERL
is related to: Blip: Biomedical Logic Programming
is related to: OWL API
is related to: CLENCH
is related to: BiNGO: A Biological Networks Gene Ontology tool
is related to: CateGOrizer
is related to: FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products
is related to: ProteInOn
is related to: GeneMerge
is related to: GraphWeb
is related to: ClueGO
is related to: CLASSIFI - Cluster Assignment for Biological Inference
is related to: GOHyperGAll
is related to: FuncAssociate: The Gene Set Functionator
is related to: GOdist
is related to: FuncExpression
is related to: FunCluster
is related to: FIVA - Functional Information Viewer and Analyzer
is related to: GARBAN
is related to: GOEx - Gene Ontology Explorer
is related to: SGD Gene Ontology Slim Mapper
is related to: GOArray
is related to: SNPsandGO
is related to: GoSurfer
is related to: GOtcha
is related to: MAPPFinder
is related to: GoAnnotator
is related to: MetaGeneProfiler
is related to: OntoGate
is related to: ProfCom - Profiling of complex functionality
is related to: SerbGO
is related to: SOURCE
is related to: Ontologizer
is related to: THEA - Tools for High-throughput Experiments Analysis
is related to: Generic GO Term Mapper
is related to: GREAT: Genomic Regions Enrichment of Annotations Tool
is related to: GoBean - a Java application for Gene Ontology enrichment analysis
is related to: TXTGate
is related to: GO-Module
is related to: IT-GOM: Integrated Tool for IC-based GO Semantic Similarity Measures
is related to: G-SESAME - Gene Semantic Similarity Analysis and Measurement Tools
is related to: MalaCards
is related to: FSST - Functional Similarity Search Tool
is related to: Expression Profiler
is related to: GOChase
is related to: GoPubMed
is related to: Whatizit
is related to: REViGO
is related to: WEGO - Web Gene Ontology Annotation Plot
is related to: Blast2GO
is related to: InterProScan
is related to: PubSearch
is related to: TrED
is related to: CharProtDB: Characterized Protein Database
is related to: VirHostNet: Virus-Host Network
is related to: Pathbase
is related to: GO Online SQL Environment (GOOSE)
is related to: Neurobehavior Ontology
is related to: InterSpecies Analysing Application using Containers
is related to: KOBAS
is related to: ConceptWiki
is related to: GeneTerm Linker
is related to: Bioconductor
is related to: ErmineJ
is related to: Gene Ontology For Functional Analysis (GOFFA)
is related to: MGI GO Browser
is related to: Comparative Toxicogenomics Database (CTD)
is related to: GOEAST - Gene Ontology Enrichment Analysis Software Toolkit
is related to: Ontology Lookup Service
is related to: LexGrid
is related to: WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
is related to: g:Profiler
is related to: OwlSim
is related to: GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
is related to: YeTFaSCo
is related to: FastSemSim
is related to: RamiGO
is related to: AutismKB
is related to: GeneCodis
is related to: FunSpec
is related to: FunNet - Transcriptional Networks Analysis
is related to: PhenoM - Phenomics of yeast Mutants
is related to: agriGO
is related to: GOblet
is related to: DynGO
is related to: SeqExpress
is related to: ProbeExplorer
is related to: ECgene: Gene Modeling with Alternative Splicing
is related to: Organelle DB
is related to: Gemma
is related to: Candidate Genes to Inherited Diseases
is related to: Proteome Analyst PA-GOSUB
is related to: Network Analysis, Visualization and Graphing TORonto
is related to: GOstat
is related to: Onto-Express To Go (OE2GO)
is related to: Tk-GO
is related to: EGAN: Exploratory Gene Association Networks
is related to: Spotfire
is related to: GOMO - Gene Ontology for Motifs
is related to: GFINDer: Genome Function INtegrated Discoverer
is related to: Generic GO Term Finder
is related to: Agile Protein Interactomes DataServer
is related to: AgingDB
is related to: UBERON
is related to: Algal Functional Annotation Tool
is related to: gsGator
is related to: Flash Gviewer
is related to: Cerebellar Development Transcriptome Database
is related to: PlantNATsDB - Plant Natural Antisense Transcripts DataBase
is related to: EASE: the Expression Analysis Systematic Explorer
is related to: PiGenome
is related to: L2L Microarray Analysis Tool
is related to: MeGO
is related to: CELDA Ontology
is related to: Diabetes Disease Portal
is related to: MatrixDB
is related to: Kidney and Urinary Pathway Knowledge Base
is related to: MouseCyc
is related to: Candida Genome Database
is related to: Honey Bee Brain EST Project
is related to: ECO
is related to: FlyMine
is related to: Gramene
is related to: 3D-Interologs
is related to: Biomine
is related to: UniProtKB
is related to: NCBI BioSystems Database
is related to: EBIMed
is related to: Coremine Medical
is related to: EMAGE Gene Expression Database
is related to: GeneMANIA
is related to: Yeast Search for Transcriptional Regulators And Consensus Tracking
is related to: GeneTrail
is related to: Magic
is related to: Mouse Genome Informatics (MGI)
is related to: FlyBase
is related to: InterPro
is related to: InnateDB
is related to: canSAR
is related to: HPRD - Human Protein Reference Database
is related to: CRCView
is related to: Integrated Manually Extracted Annotation
is related to: LegumeIP
is related to: Renal Disease Portal
is related to: PhenoGO
is related to: DOAF
is related to: OBO
is related to: biomaRt
is related to: OncoboxPD
is parent organization of: AmiGO
is parent organization of: GOlr
is parent organization of: RefGenome
is parent organization of: OBO-Edit
is parent organization of: OWLTools
is parent organization of: Gene Ontology Tools
is parent organization of: Gene Ontology Extension
is parent organization of: SO
is parent organization of: go-db-perl
is parent organization of: go-perl
works with: topGO
works with: DIANA-mirPath
works with: GOnet
is organization facet of: Alliance of Genome Resources
European Union QLRI-CT-2001-00015;
European Union QLRI-CT-2001-0098;
NHGRI P41 HG002273
PMID:23161678
PMID:10802651
Free, Freely available, Available for download biotools:go, OMICS_02278, nif-0000-02915 http://bioportal.bioontology.org/ontologies/GO, https://bio.tools/go SCR_002811 the Gene Ontology, GO, Gene Ontology Resource, Gene Ontology 2026-09-02 05:39:04 12993
Neurogenetics and Behavior Center
 
Resource Report
Resource Website
Neurogenetics and Behavior Center (RRID:SCR_002851) analysis service resource, behavioral analysis service, data or information resource, portal, production service resource, service resource, topical portal This center provides routine behavioral/cognitive testing of mice with phenotypes that are expressed as a consequence of alterations at the level of gene function, and that are relevant to basic neuroscience and to animal models of neurological and psychiatric disorders. Current Research Behavioral testing within the center involves a collaborative component in which mice provided by users are assessed for behavioral/cognitive functions. All research includes behavioral assessment of a variety of genetically altered mice provided by users. Services Provided The objective of the center is to provide a link between genetic and molecular analysis of neural function and the study of integrative systems and clinical conditions through behavioral assessment of animal models, and mouse behavioral phenotypes generated by genetic modification. Sponsors: This resource is supported by the National Center of Research Resources (Grant Number: P40 RR017688). function, gene, animal, behavioral, clinical, cognitive, disorder, model, mouse, neural, neurological, neuroscience, phenotype, psychiatric, testing has parent organization: Johns Hopkins University; Maryland; USA Free, Freely available nif-0000-25310 SCR_002851 NBC 2026-09-02 05:39:06 0
Sal-Site
 
Resource Report
Resource Website
50+ mentions
Sal-Site (RRID:SCR_002850) Sal-Site analysis service resource, data analysis service, data or information resource, database, image collection, organism-related portal, portal, production service resource, service resource, topical portal Portal that supports Ambystoma-related research and educational efforts. It is composed of several resources: Salamander Genome Project, Ambystoma EST Database, Ambystoma Gene Collection, Ambystoma Map and Marker Collection, Ambystoma Genetic Stock Center, and Ambystoma Research Coordination Network. gene, genomic, expressed sequence tag, blast, model organism, genome, salamander, animal model, genetic map, genetic marker, gene expression, limb regeneration, microarray, quantitative-pcr, rna-seq, nanostring, husbandry, embryo, limb, mutant, strain, neural, olfaction, phentotype, regeneration, renal, retina, sequence, vision, human, chicken, xenopus tropicalis, FASEB list has parent organization: University of Kentucky; Kentucky; USA NCRR R24 RR016344;
NIH Office of the Director R24 OD010435;
NSF DBI0443496;
NSF OB0242833
PMID:16359543 Free, Freely available nif-0000-25309 https://orip.nih.gov/comparative-medicine/programs/vertebrate-models SCR_002850 Ambystoma Resources for Model Amphibians Database 2026-09-02 05:39:07 92
Special Mouse Strains Resource
 
Resource Report
Resource Website
Special Mouse Strains Resource (RRID:SCR_002885) SMSR biomaterial supply resource, material resource, organism supplier Resource of special strains of mice that are valuable tools for genetic analysis of complex diseases. They include panels of recombinant inbred (RI) and chromosome substitution (CS) strains. strain panel, frozen, cryopreserved, recombinant inbred mouse, chromosome substitution mouse, consomic strain, gene, disease, strain is listed by: One Mind Biospecimen Bank Listing
is related to: One Mind Biospecimen Bank Listing
is related to: Mouse Phenome Database (MPD)
has parent organization: Jackson Laboratory
Recombinant inbred mouse, Chromosome substitution mouse, Consomic strain NCRR P40 RR016049;
NIH Office of the Director P40 OD011102
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25593 SCR_002885 Special Mouse Strains Resource (SMSR) 2026-09-02 05:39:05 0
Computational Biology Center
 
Resource Report
Resource Website
50+ mentions
Computational Biology Center (RRID:SCR_002877) data or information resource, disease-related portal, portal, topical portal, training resource Computational biology research at Memorial Sloan-Kettering Cancer Center (MSKCC) pursues computational biology research projects and the development of bioinformatics resources in the areas of: sequence-structure analysis; gene regulation; molecular pathways and networks, and diagnostic and prognostic indicators. The mission of cBio is to move the theoretical methods and genome-scale data resources of computational biology into everyday laboratory practice and use, and is reflected in the organization of cBio into research and service components ~ the intention being that new computational methods created through the process of scientific inquiry should be generalized and supported as open-source and shared community resources. Faculty from cBio participate in graduate training provided through the following graduate programs: * Gerstner Sloan-Kettering Graduate School of Biomedical Sciences * Graduate Training Program in Computational Biology and Medicine Integral to much of the research and service work performed by cBio is the creation and use of software tools and data resources. The tools that we have created and utilize provide evidence of our involvement in the following areas: * Cancer Genomics * Data Repositories * iPhone & iPod Touch * microRNAs * Pathways * Protein Function * Text Analysis * Transcription Profiling drug, evolution, experiment, gene, algorithm, bioinformatics, biology, cancer, clinical, computational, diagnostic, genome, human, initiation, kinetics, laboratory, leukemia, ligand, metastasis, microrna, mirna, model, molecular, network, pathway, phenotype, prognostic, progression, protein, regulation, research, resistance, rna, sequence, stem cell, structure, t cell, therapy, treatment, tumor is parent organization of: TMBETA-GENOME- Annotation of Beta-Barrel Membrane Proteins in Genomic Sequences Free, Freely available nif-0000-25560 SCR_002877 cBio 2026-09-02 05:39:07 71
Harvard Partners HealthCare Center for Personalized Genetic Medicine Bioinformatics Core Facility
 
Resource Report
Resource Website
Harvard Partners HealthCare Center for Personalized Genetic Medicine Bioinformatics Core Facility (RRID:SCR_000882) access service resource, analysis service resource, core facility, production service resource, service resource Core to provide gene expression data analysis service. Activities range from the provision of services to fully collaborative grant funded investigations. affymetrix, array, PCPGM, gene, expression, data, analysis, service is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156324 http://www.partners.org/researchcores/trash/bioinformatics_HPCGG.html SCR_000882 PCPGM, bioinformatics, The Partners HealthCare Center for Personalized Genetic Medicine 2026-09-02 05:38:35 0
Yandell Lab Portal
 
Resource Report
Resource Website
Yandell Lab Portal (RRID:SCR_000807) data analysis software, data or information resource, data processing software, laboratory portal, organization portal, portal, software application, software resource Sequenced genomes contain a treasure trove of information about how genes function and evolve. Getting at this information, however, is challenging and requires novel approaches that combine computer science and experimental molecular biology. My lab works at the intersection of both domains, and research in our group can be summarized as follows: generate hypotheses concerning gene function and evolution by computational means, and then test these hypotheses at the bench. This is easier said than done, as serious barriers still exist to using sequenced genomes and their annotations as starting points for experimental work. Some of these barriers lie in the computational domain, others in the experimental. Though challenging, overcoming these barriers offers exciting training opportunities in both computer science and molecular genetics, especially for those seeking a future at the intersection of both fields. Ongoing projects in the lab are centered on genome annotation and comparative genomics; exploring the relationships between sequence variation and human disease; and high-throughput biological image analysis. Current software tools available: VAAST (the Variant Annotation, Analysis & Search Tool) is a probabilistic search tool for identifying damaged genes and their disease-causing variants in personal genome sequences. VAAST builds upon existing amino acid substitution (AAS) and aggregative approaches to variant prioritization, combining elements of both into a single unified likelihood-framework that allows users to identify damaged genes and deleterious variants with greater accuracy, and in an easy-to-use fashion. VAAST can score both coding and non-coding variants, evaluating the cumulative impact of both types of variants simultaneously. VAAST can identify rare variants causing rare genetic diseases, and it can also use both rare and common variants to identify genes responsible for common diseases. VAAST thus has a much greater scope of use than any existing methodology. MAKER 2 (updated 01-16-2012) MAKER is a portable and easily configurable genome annotation pipeline. It's purpose is to allow smaller eukaryotic and prokaryotic genomeprojects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER is also easily trainable: outputs of preliminary runs can be used to automatically retrain its gene prediction algorithm, producing higher quality gene-models on seusequent runs. MAKER's inputs are minimal and its ouputs can be directly loaded into a GMOD database. They can also be viewed in the Apollo genome browser; this feature of MAKER provides an easy means to annotate, view and edit individual contigs and BACs without the overhead of a database. MAKER should prove especially useful for emerging model organism projects with minimal bioinformatics expertise and computer resources. RepeatRunner RepeatRunner is a CGL-based program that integrates RepeatMasker with BLASTX to provide a comprehensive means of identifying repetitive elements. Because RepeatMasker identifies repeats by means of similarity to a nucleotide library of known repeats, it often fails to identify highly divergent repeats and divergent portions of repeats, especially near repeat edges. To remedy this problem, RepeatRunner uses BLASTX to search a database of repeat encoded proteins (reverse transcriptases, gag, env, etc...). Because protein homologies can be detected across larger phylogenetic distances than nucleotide similarities, this BLASTX search allows RepeatRunner to identify divergent protein coding portions of retro-elements and retro-viruses not detected by RepeatMasker. RepeatRunner merges its BLASTX and RepeatMasker results to produce a single, comprehensive XML-based output. It also masks the input sequence appropriately. In practice RepeatRunner has been shown to greatly improve the efficacy of repeat identifcation. RepeatRunner can also be used in conjunction with PILER-DF - a program designed to identify novel repeats - and RepeatMasker to produce a comprehensive system for repeat identification, characterization, and masking in the newly sequenced genomes. CGL CGL is a software library designed to facilitate the use of genome annotations as substrates for computation and experimentation; we call it CGL, an acronym for Comparitive Genomics Library, and pronounce it Seagull. The purpose of CGL is to provide an informatics infrastructure for a laboratory, department, or research institute engaged in the large-scale analysis of genomes and their annotations. software, gene, genome annotation, human has parent organization: University of Utah; Utah; USA
is parent organization of: VAAST
PMID:21700766
PMID:21700266
PMID:21325948
PMID:21347285
nlx_144364 SCR_000807 2026-09-02 05:38:35 0
ROSTLAB
 
Resource Report
Resource Website
1+ mentions
ROSTLAB (RRID:SCR_000792) group A lab organization which has bases in Munich, Germany and at Columbia University and focuses its research on protein structure and function using sequence and evolutionary information. They utilize machine learning and statistical methods to analyze genetic material and its gene products. Research goals of the lab involve using protein and DNA sequences along with evolutionary information to predict aspects of the proteins relevant to the advance of biomedical research. protein, structure, function, dna, rna, gene, machine learning, statistics, analysis, protein, biomedical has parent organization: Columbia University; New York; USA
is parent organization of: PredictNLS
is parent organization of: SNPdbe
NLM LM007329;
NLM GM50291
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-31417 http://cubic.bioc.columbia.edu/services/disis SCR_000792 Rost Group 2026-09-02 05:38:35 1
Functional Annotation of the Mammalian Genome
 
Resource Report
Resource Website
10+ mentions
Functional Annotation of the Mammalian Genome (RRID:SCR_000788) FANTOM consortium, data or information resource, database, organization portal, portal International collaborative research project and database of annotated mammalian genome. Used to improve estimates of total number of genes and their alternative transcript isoforms in both human and mouse. Consortium to assign functional annotations to full length cDNAs that were collected during Mouse Encyclopedia Project at RIKEN. mammal, genome, isoform, human, gene, transcriptome, regulatory network, FASEB list is related to: CAGE Basic Viewer for Mus musculus
is related to: RIKEN integrated database of mammals
has parent organization: RIKEN Brain Science Institute
NIMH MH062261 PMID:20211142
PMID:33211864
nif-0000-30552 http://fantom.gsc.riken.jp SCR_000788 Functional Annotation of the Mammalian Genome, FANTOM, Functional Annotation of the Mammalian Genome (FANTOM) 2026-09-02 05:38:30 43
Kyoto Encyclopedia of Genes and Genomes Expression Database
 
Resource Report
Resource Website
1000+ mentions
Kyoto Encyclopedia of Genes and Genomes Expression Database (RRID:SCR_001120) KEGG Expression Database data or information resource, data repository, database, service resource, storage service resource Database for mapping gene expression profiles to pathways and genomes. Repository of microarray gene expression profile data for Synechocystis PCC6803 (syn), Bacillus subtilis (bsu), Escherichia coli W3110 (ecj), Anabaena PCC7120 (ana), and other species contributed by the Japanese research community. encyclopedia, endogenous, environment, enzyme, escherichia coli, exogenous, expression, family, functional, gene, genetic, anabaena, bacillus subtilis, biological system, biology, building block, cell, cellular, chemical, community, complex, genome, genomic, hierarchy, interaction, japanese, mapping, metabolic, metabolic pathway databases, microarray, molecular, molecular wiring, nomenclature, order, organism, ortholog, pathway, process, protein, reaction, research, sequence, specie, substance, synechocystis, FASEB list is listed by: LabWorm
is affiliated with: KEGG
has parent organization: Kyoto University; Kyoto; Japan
PMID:9847135
PMID:10592173
Free, Available for download, Freely available r3d100011570, nif-0000-21234 https://doi.org/10.17616/R3792T SCR_001120 Kyoto Encyclopedia of Genes and Genomes Expression Database 2026-09-02 05:38:34 1279
sim4cc
 
Resource Report
Resource Website
sim4cc (RRID:SCR_001204) alignment software, data processing software, image analysis software, software application, software resource Software tool as cross species spliced alignment program.Heuristic sequence alignment tool for comparing cDNA sequence with genomic sequence containing homolog of gene in another species. Cross species spliced alignment, unix, sequence alignment, cdna sequence, genomic sequence, homolog, gene, splice, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Johns Hopkins University; Maryland; USA
NLM R01 LM006845;
NSF CLS20163A;
Sloan Research Fellowship
PMID:19429899 Free, Available for download, Freely available biotools:sim4cc, OMICS_02145 https://bio.tools/sim4cc SCR_001204 2026-09-02 05:38:42 0
Omixon Target Data Analysis
 
Resource Report
Resource Website
Omixon Target Data Analysis (RRID:SCR_001207) Omixon Target commercial organization, data analysis software, data processing software, software application, software resource, software toolkit Software application suite to help clinical labs adopt next generation sequencing for the analysis of diagnostic gene targets. next-generation sequencing, gene target, windows, linux, mac, gene, diagnostic is listed by: OMICtools
is parent organization of: Omixon Target HLA Typing
License required OMICS_02141 SCR_001207 2026-09-02 05:38:36 0
betr
 
Resource Report
Resource Website
10+ mentions
betr (RRID:SCR_001332) betr software resource Software package that implements the Bayesian Estimation of Temporal Regulation algorithm to identify differentially expressed genes in microarray time-course data. differentially expression, gene, microarray, time-course is listed by: OMICtools
has parent organization: Bioconductor
PMID:20003283 Free, Available for download, Freely available OMICS_01997 http://www.bioconductor.org/packages/release/bioc/html/betr.html SCR_001332 Bayesian Estimation of Temporal Regulation 2026-09-02 05:38:34 17
Happy
 
Resource Report
Resource Website
10+ mentions
Happy (RRID:SCR_001395) HAPPY data analysis software, data processing software, software application, software resource, source code THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package for Multipoint QTL Mapping in Genetically Heterogeneous Animals (entry from Genetic Analysis Software) The method is implemented in a C-program and there is now an R version of HAPPY. You can run HAPPY remotely from their web server using your own data (or try it out on the data provided for download). qtl, quantitative trait locus, r, c, gene, genetic, genomic, ansi c, unix, irix, sunos, linux, animal model, trait, map, genotype, phenotype, haplotype, linear regression, data set, qtl mapping is listed by: Genetic Analysis Software
is listed by: Debian
has parent organization: Wellcome Trust Centre for Human Genetics
Wellcome Trust PMID:11050180
DOI:10.1073/pnas.230304397
THIS RESOURCE IS NO LONGER IN SERVICE nlx_152594 http://www.well.ox.ac.uk/~rmott/happy.html https://sources.debian.org/src/r-other-mott-happy.hbrem/ SCR_001395 reconstructing HAPlotYpes 2026-09-02 05:38:40 46

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