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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2026-07-25 12:05:58 3
Digital Curation Centre
 
Resource Report
Resource Website
1+ mentions
Digital Curation Centre (RRID:SCR_005087) DCC institution The Digital Curation Centre (DCC) is a world-leading centre of expertise in digital information curation with a focus on building capacity, capability and skills for research data management across the UK''s higher education research community. The Digital Curation Centre provides expert advice and practical help to anyone in UK higher education and research wanting to store, manage, protect and share digital research data. The DCC provides access to a range of resources including our popular How-to Guides, case studies and online services. Our training programmes aim to equip researchers and data custodians with the skills they need to manage and share date effectively. We also provide consultancy and support with issues such as policy development and data management planning. is parent organization of: DCC DIFFUSE Standards Frameworks JISC Wikidata: Q5275828, nlx_144098, grid.499933.d https://ror.org/01k9d6864 SCR_005087 Digital Curation Center 2026-07-25 12:05:59 7
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-07-25 12:05:59 3
Applied Biosystems
 
Resource Report
Resource Website
10000+ mentions
Applied Biosystems (RRID:SCR_005039) commercial organization An Antibody supplier is parent organization of: Ambion Inc. nlx_152278 SCR_005039 2026-07-25 12:05:57 32510
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-07-25 12:05:57 20
Bioworld Technology
 
Resource Report
Resource Website
1+ mentions
Bioworld Technology (RRID:SCR_005036) commercial organization An Antibody supplier nlx_152317 SCR_005036 2026-07-25 12:05:58 1
Gift of Hope Organ and Tissue Donor Network
 
Resource Report
Resource Website
Gift of Hope Organ and Tissue Donor Network (RRID:SCR_004968) Gift of Hope nonprofit organization Gift of Hope Organ & Tissue Donor Network is proud to serve as the federally designated not-for-profit agency that coordinates organ and tissue donation and supports families of donors in the northern three-quarters of Illinois and northwest Indiana. Since our inception in 1986, we have coordinated donations that have saved the lives of 17,000 organ transplant recipients and helped hundreds of thousands of other patients receive needed tissue transplants. As one of 58 organ procurement organizations (OPOs) that make up the nation''s organ donation system, we work with 179 hospitals in our donation service area. In managing the recovery, care and transportation of donated organs to transplant patients, we work closely with Illinois'' nine transplant centers, which operate 32 transplant programs. We also work with other transplant centers and other OPOs through the United Network for Organ Sharing (UNOS) to provide lifesaving organs for patients awaiting them. UNOS is the federally mandated registration center for organ transplant candidates in the United States. UNOS'' computer-based system matches donated organs with patients in need, in accordance with strict federal guidelines intended to ensure equitable distribution. is listed by: One Mind Biospecimen Bank Listing grid.477192.e, nlx_93206, ISNI: 0000 0004 0628 5713 https://ror.org/00swcah48 SCR_004968 Gift of Hope Organ & Tissue Donor Network 2026-07-25 12:05:56 0
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace, https://sources.debian.org/src/sspace/ SCR_005056 2026-07-25 12:05:58 426
HPC-CLUST
 
Resource Report
Resource Website
1+ mentions
HPC-CLUST (RRID:SCR_005052) HPC-CLUST software resource A set of tools designed to cluster large numbers (>1 million) of pre-aligned nucleotide sequences. It performs the clustering of sequences using the Hierarchical Clustering Algorithm (HCA). There are currently three different cluster metrics implemented: single-linkage, complete-linkage, and average-linkage. In addition, there are currently four sequence distance functions implemented, these are: identity (gap-gap counting as match), nogap (gap-gap being ignored), nogap-single (like nogap, but consecutive gap-nogap''s count as a single mismatch), tamura (distance is calculated with the knowledge that transitions are more likely than transversions). One advantage that HCA has over other algorithms is that instead of producing only the clustering at a given threshold, it produces the set of merges occuring at each threshold. With this approach, the clusters can afterwards very quickly be reported for every arbitrary threshold with little extra computation. This approach also allows the plotting of the variation of number of clusters with clustering threshold without requiring the clustering to be run for each threshold independently. Another feature of the way HPC-CLUST is implemented is that the single-, complete-, and average-linkage clusterings can be computed in a single run with little overhead. c++, mpi is listed by: OMICtools
has parent organization: University of Zurich; Zurich; Switzerland
PMID:24215029 OMICS_01446 SCR_005052 2026-07-25 12:05:57 5
M-pick
 
Resource Report
Resource Website
M-pick (RRID:SCR_004995) M-pick software resource A modularity-based clustering software for Operational Taxonomic Unit (OTU) picking of 16S rRNA sequences. The algorithm does not require a predetermined cut-off level, and our simulation studies suggest that it is superior to existing methods that require specified distance or variance levels to define OTUs. 16s rrna sequence, 16s rrna, rrna, sequence, binning is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
OMICS_01447 SCR_004995 M-pick: a modularity-based clustering method for OTU picking 2026-07-25 12:05:57 0
University of Manchester; Manchester; United Kingdom
 
Resource Report
Resource Website
1+ mentions
University of Manchester; Manchester; United Kingdom (RRID:SCR_004996) university Public research university in Manchester, England, formed in 2004 by merger of University of Manchester Institute of Science and Technology and Victoria University of Manchester. Second largest university in United Kingdom by enrollment. is affiliated with: OpenMinTeD
is related to: NEWMEDS
is related to: ORBITO
is related to: Open PHACTS
is related to: EMIF
is parent organization of: Smart Dictionary Lookup
is parent organization of: mlgt
is parent organization of: Utopia Docs
is parent organization of: Kidney and Urinary Pathway Knowledge Base
is parent organization of: PUMA
is parent organization of: DOSY Toolbox
is parent organization of: RightField
is parent organization of: SEEK
is parent organization of: miRBase
is parent organization of: PRINTS
is parent organization of: CHEM21
is parent organization of: Taverna
is parent organization of: SysMO-DB
is parent organization of: MethodBox
is parent organization of: OWL API
is parent organization of: X:MAP
is parent organization of: Mimas
is parent organization of: National Centre for Text Mining
is parent organization of: Chemistry Using Text Annotations
is parent organization of: TerMine
is parent organization of: Acromine Disambiguator
is parent organization of: Census Dissemination Unit
is parent organization of: Open Regulatory Annotation Database
is parent organization of: ADAPT: A Database of Affymetrix Probesets and Transcripts
is parent organization of: brat rapid annotation tool
is parent organization of: UK DNA Banking Network
is parent organization of: AcroMine
is parent organization of: BioIE: Extracting Informative Sentences From the Biomedical Literature
is parent organization of: Biocatalogue - The Life Science Web Services Registry
is parent organization of: myExperiment
is parent organization of: Software Ontology
is parent organization of: bioNerDS
is parent organization of: MorphoJ
is parent organization of: University of Manchester Bioinformatics Core Facility
is parent organization of: miRBase
is parent organization of: Simple Assignment of Spots to Surfaces
is parent organization of: AMBER parameter database
is parent organization of: University of Manchester Electron Microscopy Core Facility
is parent organization of: University of Manchester Mass Spectrometry and Separations Core Facility
is parent organization of: University of Manchester Advanced Manufacturing Platform Core Facility
is parent organization of: University of Manchester Surface Characterisation Core Facility
is parent organization of: University of Manchester Biochemical and Biophysical Sciences Technology Platform Core Facility
is parent organization of: University of Manchester Corrosion and Materials for Demanding Environments Core Facility
is parent organization of: University of Manchester Magnetic Resonance and Related Technology Platform Core Facility
is parent organization of: University of Manchester X-ray Diffraction Platform Core Facility
is parent organization of: University of Manchester Services and Equipment Core Facility
is parent organization of: University of Manchester Design, Fabrication and Testing Core Facility
is parent organization of: University of Manchester National X-ray Computed Tomography Core Facility
is parent organization of: University of Manchester Advanced Metal Development Core Facility
is parent organization of: University of Manchester BioAutomation and Biofoundry Core Facility
is parent organization of: University of Manchester Biomolecular NMR Core Facility
has organization facet: MANC-RISK-SCREEN
nlx_74265, Wikidata:Q230899, grid.5379.8, ISNI:121662407, Crossref funder ID:501100000770 https://ror.org/027m9bs27 SCR_004996 University of Manchester 2026-07-25 12:05:59 7
Bio X Cell
 
Resource Report
Resource Website
1000+ mentions
Bio X Cell (RRID:SCR_004997) commercial organization Commercial supplier and developer of in vivo antibodies. Provides antibodies and antibody production services. commercial, antibody, reagent, biomedical, research, new hampshire, SCR_019248, nlx_152318 SCR_004997 2026-07-25 12:05:57 4386
ESPRIT-Tree
 
Resource Report
Resource Website
1+ mentions
ESPRIT-Tree (RRID:SCR_005045) ESPRIT-Tree software resource Software for hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time. clustering, 16s rrna, pyrosequence is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
PMID:21596775 OMICS_01445 SCR_005045 ESPRIT-Tree: Hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time 2026-07-25 12:05:58 9
Huazhong University of Science and Technology; Wuhan; China
 
Resource Report
Resource Website
Huazhong University of Science and Technology; Wuhan; China (RRID:SCR_005047) HUST university Public research university located in Guanshan Subdistrict, Hongshan District, Wuhan, Hubei province, China. is parent organization of: AnimalTFDB
is parent organization of: Midbody, Centrosome and Kinetochore
is parent organization of: EPSD Eukaryotic Phosphorylation Site Database
ISNI:0000 0004 0368 7223, grid.33199.31, Wikidata:Q1711196, nlx_144495, Crossref funder ID:501100003397 https://ror.org/00p991c53 SCR_005047 Huazhong University of Science and Technology, Huazhong University of Science & Technology, Huazhong University of Science & Technology; Hubei; China 2026-07-25 12:06:00 0
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-07-25 12:05:58 1
AGORA
 
Resource Report
Resource Website
50+ mentions
AGORA (RRID:SCR_005070) AGORA software resource An algorithm to use optical map information directly within the de Bruijn graph framework to help produce an accurate assembly of a genome that is consistent with the optical map information provided. AGORA takes as input two data structures: OpMap ? an ordered list of fragment sizes representing the optical map; and Edges ? a list of de Bruijn graph edges with their corresponding sequences. genome assembly, genome, reconstruction is listed by: OMICtools PMID:22856673 OMICS_00039 SCR_005070 Assembly Guided by Optical Restriction Alignment 2026-07-25 12:06:01 99
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-07-25 12:05:58 89
MapAl
 
Resource Report
Resource Website
1+ mentions
MapAl (RRID:SCR_004938) MapAl software resource A software tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. Allowing an incorporation of ''gene models'' already at the alignment stage almost doubles the number of transcripts that can be measured reliably. rna?seq is listed by: OMICtools
has parent organization: BOKU University; Vienna; Austria
PMID:22485116 GNU General Public License OMICS_01261 SCR_004938 2026-07-25 12:05:59 1
Open University; Milton Keynes; United Kingdom
 
Resource Report
Resource Website
1+ mentions
Open University; Milton Keynes; United Kingdom (RRID:SCR_004931) OU university Public research university and the largest university in the UK for undergraduate education. The majority of the OU's undergraduate students are based in the United Kingdom and principally study off-campus; many of its courses can also be studied anywhere in the world. is affiliated with: OpenMinTeD
is parent organization of: Scholarly Ontologies Project
is parent organization of: Cohere
is parent organization of: Rexplore
Wikidata:Q2413375, nlx_19814, grid.10837.3d, ISNI:96069301, Crossref funder ID:100008509 https://ror.org/05mzfcs16 SCR_004931 Open University, The Open University 2026-07-25 12:05:59 3
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-07-25 12:05:58 0

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