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http://www.bioconductor.org/packages/release/bioc/html/maCorrPlot.html
Software that graphically displays correlation in microarray data that is due to insufficient normalization.
Proper citation: maCorrPlot (RRID:SCR_001348) Copy
http://www.bioconductor.org/packages/release/bioc/html/lapmix.html
Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes.
Proper citation: lapmix (RRID:SCR_001347) Copy
http://www.bioinf.jku.at/software/farms/farms.html
Software using a model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. It is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaussian measurement noise.
Proper citation: FARMS (RRID:SCR_001344) Copy
http://www.bioconductor.org/packages/release/bioc/html/OCplus.html
Software package that allows to characterize the operating characteristics of a microarray experiment, i.e. the trade-off between false discovery rate and the power to detect truly regulated genes. The package includes tools both for planned experiments (for sample size assessment) and for already collected data (identification of differentially expressed genes).
Proper citation: OCplus (RRID:SCR_001342) Copy
https://bioconductor.org/packages//2.11/bioc/html/bridge.html
Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space.
Proper citation: bridge (RRID:SCR_001343) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/CALIB.html
Software package that contains functions for normalizing spotted microarray data, based on a physically motivated calibration model. The model parameters and error distributions are estimated from external control spikes.
Proper citation: CALIB (RRID:SCR_001338) Copy
http://www.bioconductor.org/packages/release/bioc/html/LPE.html
Software library used to do significance analysis of microarray data with small number of replicates. It uses resampling based FDR adjustment, and gives less conservative results than traditional "BH" or "BY" procedures. Data accepted is raw data in txt format from MAS4, MAS5 or dChip. Data can also be supplied after normalization. LPE library is primarily used for analyzing data between two conditions.
Proper citation: LPE (RRID:SCR_001364) Copy
http://www.bioconductor.org/packages/release/bioc/html/aroma.light.html
Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes.
Proper citation: aroma.light (RRID:SCR_001312) Copy
http://www.bioconductor.org/packages/2.13/bioc/html/BeadDataPackR.html
Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform.
Proper citation: BeadDataPackR (RRID:SCR_001310) Copy
https://www.bioconductor.org/packages/release/bioc/html/OLIN.html
Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data.
Proper citation: OLIN (RRID:SCR_001304) Copy
http://www.bioconductor.org/packages/release/bioc/html/simpleaffy.html
Software package that provides high level functions for reading Affy .CEL files, phenotypic data, and then computing simple things with it, such as t-tests, fold changes and the like. It makes heavy use of the affy library. It also has some basic scatter plot functions and mechanisms for generating high resolution journal figures.
Proper citation: Simpleaffy (RRID:SCR_001302) Copy
http://www.bioconductor.org/packages/release/bioc/html/qcmetrics.html
Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats.
Proper citation: qcmetrics (RRID:SCR_001303) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/dexus.html
Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power.
Proper citation: DEXUS (RRID:SCR_001309) Copy
Software resource for multiple whole genome alignment. It uses Nucmer, a custom graph-based segmentation procedure, for pairwise alignment, and the Seqan:TCoffee's multiple alignment strategy.
Proper citation: Mugsy (RRID:SCR_001414) Copy
http://www.biostat.jhsph.edu/~hji/cisgenome/index.htm
Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis.
Proper citation: CisGenome (RRID:SCR_001558) Copy
http://pfind.ict.ac.cn/se/plink/
Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: pFind Studio: pLink (RRID:SCR_000084) Copy
http://www.tm4.org/spotfinder.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software designed for the rapid, reproducible and computer-aided analysis of microarray images and the quantification of gene expression.
Proper citation: Spotfinder (RRID:SCR_000085) Copy
http://www.computationalbioenergy.org/parallel-meta.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Open source pipeline for metagenomic data analysis, which enables efficient and parallel analysis of multiple metagenomic datasets and visualization of results for multiple samples. Can perform rapid data mining among microbial community data for comparative taxonomic and functional analysis.
Proper citation: Parallel-META (RRID:SCR_000121) Copy
http://biolemmatizer.sourceforge.net/
A domain-specific lemmatization software tool for the morphological analysis of biomedical literature.
Proper citation: BioLemmatizer (RRID:SCR_000117) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 23,2022. A metagenomic open reading frame (ORF) finding tool for the prediction of protein coding genes in short, environmental DNA sequences with unknown phylogenetic origin. The resource is based on a two-stage machine learning approach that uses linear discriminants to extract features from the ORFs. An artificial neural network then combines the features and computes a gene probability for each ORF fragment.
Proper citation: Orphelia (RRID:SCR_000119) Copy
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