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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BioCyc
 
Resource Report
Resource Website
500+ mentions
BioCyc (RRID:SCR_002298) data or information resource, database A collection of Pathway/Genome Databases which describes the genome and metabolic pathways of a single organism. The BioCyc collection of Pathway/Genome Databases (PGDBs) provides an electronic reference source on the genomes and metabolic pathways of sequenced organisms. BioCyc PGDBs are generated by software that predicts the metabolic pathway complements of completely sequenced organisms from their genome sequences. They also include the results of a number of other computational inference procedures applied to these genomes, including predictions of which genes code for missing enzymes in metabolic pathways, and predicted operons. The BioCyc Web site provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions. The databases within the BioCyc collection are organized into tiers according to the amount of manual review and updating they have received. Tier 1 PGDBs have been created through intensive manual efforts, and receive continuous updating. Tier 2 PGDBs were computationally generated by the PathoLogic program, and have undergone moderate amounts of review and updating. Tier 3 PGDBs were computationally generated by the PathoLogic program, and have undergone no review and updating. There are 967 DBs in Tier 3. The downloadable version of BioCyc that includes the Pathway Tools software provides more speed and power than the BioCyc Web site. database, pathway/genome databases, PGDB, genome, metabolic pathway, microbiome, FASEB list uses: Pathway Tools
is used by: PathCase Pathways Database System
lists: Pathway Tools
lists: EcoCyc
lists: MetaCyc
lists: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is listed by: LabWorm
is listed by: Human Microbiome Project
is related to: Pathway Tools
is related to: PathCase Pathways Database System
is related to: EcoCyc
is related to: MetaCyc
is related to: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is related to: EcoCyc
is related to: Gramene
is related to: NCBI BioSystems Database
is related to: KOBAS
is related to: Tuberculosis Database
is related to: Pathway Tools
has parent organization: Stanford Research Institute International
NIGMS GM080746 PMID:16246909 Restricted nif-0000-00369, r3d100011259 https://doi.org/10.17616/R36G8H SCR_002298 BioCyc Database Collection 2026-07-28 09:40:23 970
MatrixDB
 
Resource Report
Resource Website
50+ mentions
MatrixDB (RRID:SCR_001727) MatrixDB data or information resource, service resource, database, production service resource Freely available database focused on interactions established by extracellular proteins and polysaccharides, taking into account the multimeric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB is an active member of the International Molecular Exchange (IMEx) consortium and has adopted the PSI-MI standards for annotating and exchanging interaction data. It includes interaction data extracted from the literature by manual curation, and offers access to relevant data involving extracellular proteins provided by the IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. The database reports mammalian protein-protein and protein-carbohydrate interactions involving extracellular molecules. Interactions with lipids and cations are also reported. MatrixDB is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available. MatrixDB provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells. MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa. Statistics (2013): 2283 extracellular matrix interactions including 2095 protein-protein and 169 protein-glycosaminoglycan interactions. extracellular, protein fragment, biomolecule, cation, cleavage, collagen, glycosaminoglycan, human, interaction, laminin, lipid, mammalian, matricryptin, matrikin, matrix, molecule, monomer, mulimerization, multimer, polysaccharide, protein, protein-carbohydrate interaction, protein-protein interaction, recognition, thrombospondin, interactome, extracellular protein, protein-polysaccharide interaction, extracellular interaction, molecular interaction, model organism, inorganic, small molecule-protein, small molecule, extracellular matrix protein, protein-glycosaminoglycan interaction, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Gene Ontology
is related to: PSI-MI
is related to: HPRD - Human Protein Reference Database
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: IntAct
has parent organization: Claude Bernard University Lyon 1; Lyon; France
European Union contract FP7-HEALTH-2007-223411 PMID:20852260
PMID:19147664
THIS RESOURCE IS NO LONGER IN SERVICE biotools:matrixdb, r3d100010672, nif-0000-10226 https://bio.tools/matrixdb, https://doi.org/10.17616/R3M03H http://matrixdb.ibcp.fr/ SCR_001727 MatrixDB: Extracellular Matrix Interactions Database, Extracellular Matrix Interactions Database 2026-07-28 09:40:15 86
CSHL - Hannon Lab
 
Resource Report
Resource Website
50+ mentions
CSHL - Hannon Lab (RRID:SCR_005982) Hannon Lab data or information resource, organization portal, portal, laboratory portal The Hannon laboratory comprises a broad spectrum of programs in small RNA biology, mammalian genetics and genomics. We study RNAi and related pathways in a wide variety of organisms to extract common themes that define both the mechanisms by which small RNAs act and the biological processes which they impact. Currently, we focus on microRNAs, endogenous siRNAs and piRNAs and their roles in gene regulation, cancer biology, stem cell biology and in defense of the genome against transposons. In collaboration with Steve Elledge (Harvard) and Scott Lowe (CSHL), we develop genome-wide shRNA tools for RNAi-based genetics in mammalian cells, and we are now producing similar collections of artificial microRNAs for Arabidopsis with Detlef Weigel (MPI), Dick McCombie (CSHL) and Rob Martienssen (CSHL) as part of the 2010 project (see 2010.cshl.edu). Our genomic efforts include the application of RNAi-based genetic screens to cancer biology and stem cells. We also make heavy use of next generation sequencing methodologies for probing small RNA populations, in part as a member of the ENCODE consortium (with Tom Gingeras, CSHL). Finally, we develop (with Dick McCombie) and apply focal re-sequencing methods for identifying disease relevant mutations, for probing the epigenetic landscape and for the study of human evolution. rnai, rna, mammal, genetics, genomics, microrna, sirna, pirna, gene regulation, cancer biology, stem cell biology, defense, genome, transposon, cancer, stem cell has parent organization: Cold Spring Harbor Laboratory nlx_151354 SCR_005982 Cold Spring Harbor Laboratory - Hannon Lab 2026-07-28 09:41:31 66
Brad Smith Magnetic Resonance Imaging of Embryos
 
Resource Report
Resource Website
Brad Smith Magnetic Resonance Imaging of Embryos (RRID:SCR_006300) Brad Smith MRI of Embryos image collection, data or information resource, data set, video resource Data set of image collections and movies including Magnetic Resonance Imaging of Embryos, Human Embryo Imaging, MRI of Cardiovascular Development, and Live Embryo Imaging. Individual MRI slice images, three-dimensional images, animations, stereo-pair animations, animations of organ systems, and photo-micrographs are included. embryo, magnetic resonance imaging, embryonic development, magnetic resonance microscopy, cardiovascular development, cardiovascular, development, heart, blood vessel, in-utero, in-vitro, embryonic mouse, newborn mouse, embryonic human is related to: Magnetic Resonance Microscopy of Mouse Embryo Specimens
is related to: Multi-Dimensional Human Embryo
has parent organization: University of Michigan; Ann Arbor; USA
Normal, Mutant, Gentically-manipulated nlx_151971 SCR_006300 Brad Smith Research MRI of Embryos, Brad Smith Research 2026-07-28 09:41:34 0
GOblet
 
Resource Report
Resource Website
1+ mentions
GOblet (RRID:SCR_006998) GOblet software application, service resource, data analysis service, software resource, production service resource, analysis service resource Tool that performs annotation based on GO and pathway terms for anonymous cDNA or protein sequences. It uses the species independent GO structure and vocabulary together with a series of protein databases collected from various sites, to perform a detailed GO annotation by sequence similarity searches. The sensitivity and the reference protein sets can be selected by the user. GOblet runs automatically and is available as a public service on our web server. GOblet expects query sequences to be in FASTA-Format (with header-lines). Protein and nucleotide sequences are accepted. Total size of all sequences submitted per request should not be larger than 50kb currently. For security reasons: Larger post's will be rejected. Due to limited capacities the queries may be processed in batches depending on the server load. The output of the BLAST job is filtered automatically and the relevant hits are displayed. In addition, the respective GO-terms are shown together with the complete GO-hierarchy of parent terms., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, sequence, cdna, ontology or annotation browser, pathway, term enrichment, clustering, virus, genomic, protein, nucleotide is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
BMBF PMID:20134064
PMID:15215401
PMID:12824400
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30624, OMICS_02271 http://goblet.molgen.mpg.de SCR_006998 2026-07-28 09:41:42 6
NetOGlyc
 
Resource Report
Resource Website
500+ mentions
NetOGlyc (RRID:SCR_009026) NetOGlyc software application, service resource, data analysis service, software resource, production service resource, analysis service resource Server that produces predictions of mucin-type GalNAc O-glycosylation sites in mammalian proteins. neural network, predict, mucin, galnac, o-glycosylation site, protein, o-glycosylation, glycoprotein, o-glycoproteome, glycosite, proteome, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: CBS Prediction Servers
PMID:23584533 Acknowledgement requested nlx_153864, biotools:netoglyc https://bio.tools/netoglyc SCR_009026 NetOGlyc Server 2026-07-28 09:42:17 601
TargetScan
 
Resource Report
Resource Website
10000+ mentions
TargetScan (RRID:SCR_010845) service resource, data analysis service, data access protocol, software resource, production service resource, web service, analysis service resource Web tool to predict biological targets of miRNAs by searching for presence of conserved 8mer, 7mer and 6mer sites that match seed region of each miRNA. Nonconserved sites are also predicted and sites with mismatches in seed region that are compensated by conserved 3' pairing. Used to search for predicted microRNA targets in mammals. predict, biological, target, miRNA, conserved, 8mer, 7mer, site, match seed, region, nonconserved, mismatched, pair is listed by: OMICtools
is listed by: SoftCite
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
NIGMS GM067031;
Howard Hughes Medical Institute ;
NSF Graduate Research Fellowship
PMID:26267216 Free, Freely available OMICS_00420 http://www.targetscan.org/vert_71/ SCR_010845 TargetScanFly 2026-07-28 09:42:58 10783
Cell Type Ontology
 
Resource Report
Resource Website
1+ mentions
Cell Type Ontology (RRID:SCR_004251) CL controlled vocabulary, data or information resource, ontology Ontology designed as a structured controlled vocabulary for cell types. It was constructed for use by the model organism and other bioinformatics databases. It includes cell types from prokaryotes, mammals, and fungi. The ontology is available in the formats adopted by the Open Biological Ontologies umbrella and is designed to be used in the context of model organism genome and other biological databases. cell ontology, ontology repository is listed by: BioPortal
is listed by: Ontology Lookup Service
is related to: CELDA Ontology
is related to: OBO
is related to: Cell Line Knowledge Base
BBSRC ;
MRC ;
NIH ;
NSF DBI-9978564;
NSF PGRP-0321666
PMID:15693950 Free, Freely available nlx_26501 http://purl.bioontology.org/ontology/CL http://cellontology.org, http://www.obofoundry.org/cgi-bin/detail.cgi?id=cell, SCR_004251 cellontology.org, Obo-cell-type, Cell Ontology 2026-07-28 09:40:56 6
MamPolMammalia Polymorphism Database
 
Resource Report
Resource Website
MamPolMammalia Polymorphism Database (RRID:SCR_007769) MamPol data or information resource, database Database providing a collection of all the existing polymorphic sequences in the Mammalia group. It allows the search for any polymorphic set according to different parameter values of nucleotide diversity. For data collection, diversity measures and updating they use PDA, a pipeline made of a set of Perl modules that automates the process of sequence retrieving, grouping, aligning and estimating diversity parameters from GenBank sequences. Diversity measures, including polymorphism estimates in synonymous and non-synonymous sites, linkage disequilibrium and codon bias, are calculated for each polymorphic set in different functional regions. The database also includes the primary information retrieved from different external sources: the mammalian publicly available nucleotide sequences (excluding ESTs, STSs, GSSs, working draft and patents) with their annotations and references from GenBank, and the cross-references to the PopSet database. The database content is daily updated, and records are assigned unique and permanent MamPol identification numbers to facilitate cross-database referencing. polymorphism has parent organization: Autonomous University of Barcelona; Barcelona; Spain nif-0000-03100 SCR_007769 2026-07-28 09:41:53 0
ProtChemSI
 
Resource Report
Resource Website
1+ mentions
ProtChemSI (RRID:SCR_006115) ProtChemSI data or information resource, database The database of protein-chemical structural interactions includes all existing 3D structures of complexes of proteins with low molecular weight ligands. When one considers the proteins and chemical vertices of a graph, all these interactions form a network. Biological networks are powerful tools for predicting undocumented relationships between molecules. The underlying principle is that existing interactions between molecules can be used to predict new interactions. For pairs of proteins sharing a common ligand, we use protein and chemical superimpositions combined with fast structural compatibility screens to predict whether additional compounds bound by one protein would bind the other. The current version includes data from the Protein Data Bank as of August 2011. The database is updated monthly. protein, chemical, 3d structure, biological network, interaction, ligand, prediction, fasta, fasta sequence, smiles string, complex, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Heidelberg University; Baden-Wurttemberg; Germany
PMID:21573205 Acknowledgement requested nlx_151590, biotools:protchemsi https://bio.tools/protchemsi SCR_006115 Protein-Chemical Structural Interactions, ProtChemSI: protein-chemical interaction database, ProtChemSI - the database of protein-chemical structural interactions 2026-07-28 09:41:31 3
HaploReg
 
Resource Report
Resource Website
1000+ mentions
HaploReg (RRID:SCR_006796) HaploReg data or information resource, database HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. Using linkage disequilibrium (LD) information from the 1000 Genomes Project, linked SNPs and small indels can be visualized along with their predicted chromatin state in nine cell types, conservation across mammals, and their effect on regulatory motifs. HaploReg is designed for researchers developing mechanistic hypotheses of the impact of non-coding variants on clinical phenotypes and normal variation. chromatin state, conservation, regulatory motif, alteration, variant, chromatin, motif, annotation, genome, variation, genome-wide association study, refsnp, refseq gene, snp, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Broad Institute
NHGRI R01-HG004037;
NHGRI RC1-HG005334;
NSF 0644282
PMID:22064851 biotools:HaploReg, nlx_151407 http://compbio.mit.edu/HaploReg, https://bio.tools/HaploReg SCR_006796 2026-07-28 09:41:39 1004
UM Miller School of Medicine Division of Comparative Pathology
 
Resource Report
Resource Website
UM Miller School of Medicine Division of Comparative Pathology (RRID:SCR_012492) UM Miller School of Medicine Division of Comparative Pathology access service resource, service resource, core facility The Division of Comparative Pathology is a full service veterinary pathology laboratory with both clinical pathology and histology services. Routine hematology and serum biochemistry testing is available for multiple species; we work well with low volume samples. Specialized testing is available or can be implemented as needed. Routine histology services including processing, embedding, and sectioning are available with many routine and special staining options. is listed by: ScienceExchange
has parent organization: University of Miami Miller School of Medicine; Florida; USA
SciEx_262 SCR_012492 University of Miami Leonard M. Miller School of Medicine Division of Comparative Pathology, University of Miami Miller School of Medicine Division of Comparative Pathology 2026-07-28 09:43:06 0

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