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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GeneMANIA
 
Resource Report
Resource Website
1000+ mentions
GeneMANIA (RRID:SCR_005709) GeneMANIA analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource Data analysis service to predict the function of your favorite genes and gene sets. Indexing 1,421 association networks containing 266,984,699 interactions mapped to 155,238 genes from 7 organisms. GeneMANIA interaction networks are available for download in plain text format. GeneMANIA finds other genes that are related to a set of input genes, using a very large set of functional association data. Association data include protein and genetic interactions, pathways, co-expression, co-localization and protein domain similarity. You can use GeneMANIA to find new members of a pathway or complex, find additional genes you may have missed in your screen or find new genes with a specific function, such as protein kinases. Your question is defined by the set of genes you input. If members of your gene list make up a protein complex, GeneMANIA will return more potential members of the protein complex. If you enter a gene list, GeneMANIA will return connections between your genes, within the selected datasets. GeneMANIA suggests annotations for genes based on Gene Ontology term enrichment of highly interacting genes with the gene of interest. GeneMANIA is also a gene recommendation system. GeneMANIA is also accessible via a Cytoscape plugin, designed for power users. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, association data, protein interaction, genetic interaction, pathway, co-expression, co-localization, protein, software library, statistical analysis, term enrichment, analysis, browser, gene ontology, gene predicting, gene prioritization, database or data warehouse, other analysis, interaction browser, protein-protein interaction, interaction, FASEB list is listed by: Gene Ontology Tools
is related to: Cytoscape
is related to: Gene Ontology
is related to: PSICQUIC Registry
has parent organization: University of Toronto; Ontario; Canada
Genome Canada ;
Ontario Ministry of Research and Innovation 2007-OGI-TD-05
PMID:20576703
PMID:18613948
PMID:20926419
Open unspecified license, Free for academic use nlx_149159, r3d100013978 https://doi.org/10.17616/R31NJNA2 SCR_005709 2026-08-29 11:22:22 4535
GoFish
 
Resource Report
Resource Website
1+ mentions
GoFish (RRID:SCR_005682) GoFish analysis service resource, data analysis service, production service resource, service resource, software resource, source code Software program, available as a Java applet online or to download, allows the user to select a subset of Gene Ontology (GO) attributes, and ranks genes according to the probability of having all those attributes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, ontology or annotation browser, java, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
has parent organization: Harvard Medical School; Massachusetts; USA
Aventis Pharmaceuticals ;
Howard Hughes Medical Institute ;
NHGRI
PMID:12691998 THIS RESOURCE IS NO LONGER IN SERVICE biotools:gofish, nlx_149126, OMICS_02272 http://llama.mshri.on.ca/Software.html, https://bio.tools/gofish SCR_005682 2026-08-29 11:22:24 1
Pittsburgh Center for Kidney Research Model Organisms
 
Resource Report
Resource Website
Pittsburgh Center for Kidney Research Model Organisms (RRID:SCR_015288) access service resource, core facility, resource, service resource Core that uses the yeast S. cerevisiae and the zebrafish D. rerio to dissect fundamental aspects of kidney development and protein structure and function. renal disease, protein disorders, kidney disease, zebrafish is listed by: NIDDK Information Network (dkNET)
has parent organization: Pittsburgh Center for Kidney Research
is organization facet of: Pittsburgh Center for Kidney Research
NIDDK P30DK079307;
University of Pittsburgh School of Medicine; Pennsylvania; USA ;
Icahn School of Medicine at Mount Sinai; New York; USA
Available to the research community SCR_015288 2026-08-29 11:32:54 0
DNAtraffic
 
Resource Report
Resource Website
DNAtraffic (RRID:SCR_008886) DNAtraffic data or information resource, database DNAtraffic database is dedicated to be an unique comprehensive and richly annotated database of genome dynamics during the cell life. DNAtraffic contains extensive data on the nomenclature, ontology, structure and function of proteins related to control of the DNA integrity mechanisms such as chromatin remodeling, DNA repair and damage response pathways from eight model organisms commonly used in the DNA-related study: Homo sapiens, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Escherichia coli and Arabidopsis thaliana. DNAtraffic contains comprehensive information on diseases related to the assembled human proteins. Database is richly annotated in the systemic information on the nomenclature, chemistry and structure of the DNA damage and drugs targeting nucleic acids and/or proteins involved in the maintenance of genome stability. One of the DNAtraffic database aim is to create the first platform of the combinatorial complexity of DNA metabolism pathway analysis. Database includes illustrations of pathway, damage, protein and drug. Since DNAtraffic is designed to cover a broad spectrum of scientific disciplines it has to be extensively linked to numerous external data sources. Database represents the result of the manual annotation work aimed at making the DNAtraffic database much more useful for a wide range of systems biology applications. DNAtraffic database is freely available and can be queried by the name of DNA network process, DNA damage, protein, disease, and drug. dna, cell cycle, genome, nomenclature, ontology, structure, function, protein, chromatin remodeling, dna repair, damage response pathway, pathway, damage, drug, annotation, disease, dna network process, dna damage, gene sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Polish Academy of Sciences Warsaw; Warsaw; Poland
Norwegian Financial Mechanism PNRF-143-AI-1/07;
Polish Ministry of Science and Higher Education N N301 165835
PMID:22110027 Free biotools:dnatraffic, nlx_151312 https://bio.tools/dnatraffic SCR_008886 DNAtraffic database 2026-08-29 11:30:20 0
GeneTerm Linker
 
Resource Report
Resource Website
1+ mentions
GeneTerm Linker (RRID:SCR_006385) GTLinker analysis service resource, data analysis service, production service resource, service resource Web application that filters and links enriched output data identifying sets of associated genes and terms, producing metagroups of coherent biological significance. The method uses fuzzy reciprocal linkage between genes and terms to unravel their functional convergence and associations. It can also be accessed through its web service. gene, functional annotation, function, functional metagroup, p-value, annotation, web service is listed by: OMICtools
is related to: Gene Ontology
is related to: KEGG
is related to: InterPro
has parent organization: Spanish National Research Council; Madrid; Spain
PMID:21949701 Acknowledgement requested OMICS_02227 SCR_006385 GeneTerm Linker - post enrichment functional association by non-redundant reciprocal linkage 2026-08-29 11:29:40 2
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
 
Resource Report
Resource Website
500+ mentions
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool (RRID:SCR_006848) GOrilla analysis service resource, data analysis service, production service resource, service resource A tool for identifying and visualizing enriched GO terms in ranked lists of genes. It can be run in one of two modes: * Searching for enriched GO terms that appear densely at the top of a ranked list of genes or * Searching for enriched GO terms in a target list of genes compared to a background list of genes. gene, genetic, ontology, ontology or annotation visualization, statistical analysis, term enrichment, visualization, analysis, protein is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
European Union FP6 ;
Yeshaya Horowitz Association
PMID:19192299 Acknowledgement requested, Free, Public nlx_80425, OMICS_02282 SCR_006848 Gene Ontology enRIchment anaLysis and visuaLizAtion tool, GOrilla: Gene Ontology Enrichment Analysis Visualization Tool 2026-08-29 11:29:45 524
eSLDB - eukaryotic Subcellular Localization database
 
Resource Report
Resource Website
1+ mentions
eSLDB - eukaryotic Subcellular Localization database (RRID:SCR_000052) eSLDB data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 22,2022. database of protein subcellular localization annotation for eukaryotic organisms. It contains experimental annotations derived from primary protein databases, homology based annotations and computational predictions. proteome, protein, homology has parent organization: University of Bologna; Bologna; Italy European Union VI Framework Programme PMID:17108361 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02815 SCR_000052 eukaryotic Subcellular Localization database 2026-08-29 11:29:04 1
Lifespan Observations Database
 
Resource Report
Resource Website
1+ mentions
Lifespan Observations Database (RRID:SCR_001609) Lifespan Observations Database data or information resource, database Database that collects published lifespan data across multiple species. The entire database is available for download in various formats including XML, YAML and CSV. lifespan, phenotype, intervention, gene, compound, publication is used by: NIF Data Federation
is used by: Aging Portal
is related to: MONARCH Initiative
has parent organization: Sageweb
Aging THIS RESOURCE IS NO LONGER IN SERVICE nlx_153873 http://sageweb.org/lifespandb SCR_001609 Sageweb Lifespan Observation Database 2026-08-29 11:29:13 1
MINT
 
Resource Report
Resource Website
1000+ mentions
MINT (RRID:SCR_001523) MINT data or information resource, database A database that focuses on experimentally verified protein-protein interactions mined from the scientific literature by expert curators. The curated data can be analyzed in the context of the high throughput data and viewed graphically with the MINT Viewer. This collection of molecular interaction databases can be used to search for, analyze and graphically display molecular interaction networks and pathways from a wide variety of species. MINT is comprised of separate database components. HomoMINT, is an inferred human protein interatction database. Domino, is database of domain peptide interactions. VirusMINT explores the interactions of viral proteins with human proteins. The MINT connect viewer allows you to enter a list of proteins (e.g. proteins in a pathway) to retrieve, display and download a network with all the interactions connecting them. protein-protein interaction, protein, interaction, virus, peptide, organelle co-localization, pathway, molecular interaction, papillomavirus, epstein-barr virus, hepatitis b virus, hepatitis c virus, human adenovirus, human herpesvirus, human immunodeficiency virus, influenza a virus, vaccinia virus, simian virus 40, virus strains, virus protein, orthologous protein, network, proteomics, ortholog, FASEB list uses: IntAct
uses: PSI-MI
is listed by: re3data.org
is affiliated with: IMEx - The International Molecular Exchange Consortium
is related to: MPIDB
is related to: TissueNet - The Database of Human Tissue Protein-Protein Interactions
is related to: InteroPorc
is related to: Interaction Reference Index
is related to: Pathway Commons
is related to: ConsensusPathDB
is related to: VirusMINT
is related to: PSICQUIC Registry
is related to: Agile Protein Interactomes DataServer
has parent organization: University of Rome Tor Vergata; Rome; Italy
works with: IMEx - The International Molecular Exchange Consortium
European Union ;
ENFIN ;
Interaction Proteome Project ;
IMEx - The International Molecular Exchange Consortium ;
HUPO Proteomics Standards Initiative ;
AIRC Associazione Italiana per la Ricerca sul Cancro
PMID:22096227
PMID:24234451
PMID:19897547
PMID:18592188
PMID:18551417
PMID:18428712
PMID:17135203
PMID:11911893
nlx_152821, r3d100010414 https://doi.org/10.17616/R38S3B SCR_001523 MINT, the Molecular INTeraction database, Molecular Interactions Database, Molecular INTeraction database, MINT - the Molecular INTeraction database 2026-08-29 11:29:18 1141
UniProt
 
Resource Report
Resource Website
10000+ mentions
UniProt (RRID:SCR_002380) UniProt data or information resource, database Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB. collection, protein, sequence, annotation, data, functional, information is used by: LIPID MAPS Proteome Database
is used by: ChannelPedia
is used by: Open PHACTS
is used by: DisGeNET
is used by: Smart Dictionary Lookup
is used by: MitoMiner
is used by: Cytokine Registry
is used by: MobiDB
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is used by: Phospho.ELM
is used by: GEROprotectors
is used by: SwissLipids
is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: LabWorm
is related to: Clustal W2
is related to: UniProt DAS
is related to: UniParc at the EBI
is related to: ProDom
is related to: LegumeIP
is related to: Pathway Commons
is related to: NIH Data Sharing Repositories
is related to: FlyMine
is related to: IMEx - The International Molecular Exchange Consortium
is related to: 3D-Interologs
is related to: Biomine
is related to: EBIMed
is related to: STOP
is related to: Coremine Medical
is related to: BioExtract
is related to: STRAP
is related to: GOTaxExplorer
is related to: GoAnnotator
is related to: IT-GOM: Integrated Tool for IC-based GO Semantic Similarity Measures
is related to: Whatizit
is related to: MOPED - Model Organism Protein Expression Database
is related to: Polbase
is related to: PredictSNP
is related to: PSICQUIC Registry
is related to: IntAct
is related to: p300db
is related to: UniProt Proteomes
is related to: SARS-CoV-2 mutation effects and 3D structure prediction from sequence covariation
has parent organization: European Bioinformatics Institute
has parent organization: SIB Swiss Institute of Bioinformatics
has parent organization: Protein Information Resource
is parent organization of: UniProtKB
is parent organization of: NEWT
is parent organization of: UniParc
is parent organization of: UniProt Chordata protein annotation program
is parent organization of: UniRef
works with: Genotate
works with: CellPhoneDB
works with: MOLEonline
works with: MiMeDB
ARUK ;
British Heart Foundation ;
EMBL ;
NCI ;
NCRR P20 RR016472;
NEI ;
NHGRI P41 HG02273;
NHGRI U24 HG007722;
NHGRI U41 HG006104;
NHLBI ;
NIAID ;
NIA ;
NIDDK ;
NIGMS 5R01GM080646;
NIGMS R01 GM080646;
NIMH ;
NLM G08 LM010720;
NSF DBI-0850319;
PDUK
PMID:19843607
PMID:18836194
PMID:18045787
PMID:17142230
PMID:16381842
PMID:15608167
PMID:14681372
nif-0000-00377, SCR_018750, r3d100010357 http://www.ebi.uniprot.org, http://www.uniprot.org/uniprot/, http://www.pir.uniprot.org, ftp://ftp.uniprot.org, https://doi.org/10.17616/R3BW2M SCR_002380 , The Universal Protein Resource, Universal Protein Resource, UNIPROT Universal Protein Resource 2026-08-29 11:29:17 19823
SGD
 
Resource Report
Resource Website
1000+ mentions
SGD (RRID:SCR_004694) SGD, SGD LOCUS, SGD REF data or information resource, database A curated database that provides comprehensive integrated biological information for Saccharomyces cerevisiae along with search and analysis tools to explore these data. SGD allows researchers to discover functional relationships between sequence and gene products in fungi and higher organisms. The SGD also maintains the S. cerevisiae Gene Name Registry, a complete list of all gene names used in S. cerevisiae which includes a set of general guidelines to gene naming. Protein Page provides basic protein information calculated from the predicted sequence and contains links to a variety of secondary structure and tertiary structure resources. Yeast Biochemical Pathways allows users to view and search for biochemical reactions and pathways that occur in S. cerevisiae as well as map expression data onto the biochemical pathways. Literature citations are provided where available. database, yeast, pathway, analysis, gene, nomenclature, predicted sequence, fungi, functional relationship, protein structure, bio.tools, FASEB list uses: InterMOD
is used by: NIF Data Federation
is used by: PhenoGO
is listed by: re3data.org
is listed by: OMICtools
is listed by: InterMOD
is listed by: bio.tools
is listed by: Debian
is affiliated with: InterMOD
is related to: AmiGO
is related to: Yeast Search for Transcriptional Regulators And Consensus Tracking
is related to: HomoloGene
is related to: TXTGate
is related to: PhenoGO
has parent organization: Stanford University School of Medicine; California; USA
has parent organization: Stanford University; Stanford; California
is parent organization of: Ascomycete Phenotype Ontology
is parent organization of: SGD Gene Ontology Slim Mapper
is organization facet of: Alliance of Genome Resources
NHGRI 5P41HG001315-11;
NHGRI 5P41HG002273-05;
NHGRI 5U41HG001315-18;
NHGRI 2U41HG002273-13;
NHGRI 5R01HG004834-04
PMID:24265222
PMID:12519985
PMID:9399804
Free for academic use, The community can contribute to this resource, Non-commercial nif-0000-03456, biotools:sgd, r3d100010419, OMICS_01661 https://bio.tools/sgd, https://doi.org/10.17616/R3N313 http://genome-www.stanford.edu/Saccharomyces/ SCR_004694 SGD LOCUS, Saccharomyces Genome Database, SGD REF 2026-08-29 11:29:28 1950
SwissRegulon
 
Resource Report
Resource Website
10+ mentions
SwissRegulon (RRID:SCR_005333) SwissRegulon data or information resource, database A database of genome-wide annotations of regulatory sites. The predictions are based on Bayesian probabilistic analysis of a combination of input information including: * Experimentally determined binding sites reported in the literature. * Known sequence-specificities of transcription factors. * ChIP-chip and ChIP-seq data. * Alignments of orthologous non-coding regions. Predictions were made using the PhyloGibbs, MotEvo, IRUS and ISMARA algorithms developed in their group, depending on the data available for each organism. Annotations can be viewed in a Gbrowse genome browser and can also be downloaded in flat file format. genome, binding site, transcription factor, genome-wide annotation, annotation, chip-chip, chip-seq, non-coding region, promoter, motif, transcript, regulatory motif, genome browser, FASEB list is listed by: OMICtools
has parent organization: SIB Swiss Institute of Bioinformatics
PMID:23180783
PMID:17130146
Acknowledgement requested nif-0000-03524, OMICS_00543 SCR_005333 SwissRegulon Database 2026-08-29 11:29:34 46
BiGG Database
 
Resource Report
Resource Website
100+ mentions
BiGG Database (RRID:SCR_005809) BiGG data or information resource, database A knowledgebase of Biochemically, Genetically and Genomically structured genome-scale metabolic network reconstructions. BiGG integrates several published genome-scale metabolic networks into one resource with standard nomenclature which allows components to be compared across different organisms. BiGG can be used to browse model content, visualize metabolic pathway maps, and export SBML files of the models for further analysis by external software packages. Users may follow links from BiGG to several external databases to obtain additional information on genes, proteins, reactions, metabolites and citations of interest. biochemical, genetics, genomics, genome, metabolic network, reconstruction, model, metabolic pathway, gene, protein, reaction, metabolite, metabolic reconstruction, compound, pathway, FASEB list uses: SBML
is used by: BiGGR
is listed by: 3DVC
has parent organization: University of California at San Diego; California; USA
NIH ;
Ruth L. Kirschstein National Research Service Award - NIH Bioinformatics Training ;
University of California at San Diego; California; USA ;
Calit2 summer research scholarship ;
NIGMS GM00806-06
PMID:20426874 nlx_149299, r3d100011567 https://doi.org/10.17616/R3MG9M SCR_005809 BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions, BiGG - a Biochemical Genetic and Genomic knowledgebase 2026-08-29 11:29:38 145
UniPROBE
 
Resource Report
Resource Website
100+ mentions
UniPROBE (RRID:SCR_005803) UniPROBE data or information resource, database Database that hosts experimental data from universal protein binding microarray (PBM) experiments (Berger et al., 2006) and their accompanying statistical analyses from prokaryotic and eukaryotic organisms, malarial parasites, yeast, worms, mouse, and human. It provides a centralized resource for accessing comprehensive data on the preferences of proteins for all possible sequence variants ("words") of length k ("k-mers"), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. The database's web tools include a text-based search, a function for assessing motif similarity between user-entered data and database PWMs, and a function for locating putative binding sites along user-entered nucleotide sequences. protein, in vitro, dna binding, protein binding, genetics, dna, nucleotide sequence, sequence variant, k-mer, position weight matrix, graphical sequence logo, motif, motif similarity, binding site, microarray, protein-dna interaction, protein binding microarray probe sequence, probe, FASEB list is listed by: re3data.org
is listed by: OMICtools
PMID:21037262
PMID:18842628
Acknowledgement requested, Academic research use license nif-0000-03611, OMICS_00546, r3d100010557 http://thebrain.bwh.harvard.edu/pbms/webworks_pub/, https://doi.org/10.17616/R35C9J SCR_005803 UniPROBE Database, Universal Protein Binding Microarray Resource for Oligonucleotide Binding Evaluation, Universal PBM Resource for Oligonucleotide Binding Evaluation 2026-08-29 11:29:39 151
Yeast Resource Center
 
Resource Report
Resource Website
1+ mentions
Yeast Resource Center (RRID:SCR_007942) YRC biomedical technology research center, training resource Biomedical technology research center that (1) exploits the budding yeast Saccharomyces cerevisiae to develop novel technologies for investigating and characterizing protein function and protein structure (2) facilitates research and extension of new technologies through collaboration, and (3) actively disseminates data and technology to the research community. Through collaboration, the YRC freely provides resources and expertise in six core technology areas: Protein Tandem Mass Spectrometry, Protein Sequence-Function Relationships, Quantitative Phenotyping, Protein Structure Prediction and Design, Fluorescence Microscopy, Computational Biology. systems biology technology center, protein function, protein structure, mass spectrometry, protein, structure prediction, fluorescence microscopy, computational biology, sequence, function, phenotyping has parent organization: University of Washington; Seattle; USA NCRR ;
NIGMS P41 GM103533
nif-0000-03650 SCR_007942 YRC 2026-08-29 11:31:54 6
InteroPorc
 
Resource Report
Resource Website
1+ mentions
InteroPorc (RRID:SCR_002067) InteroPorc analysis service resource, data analysis service, data analysis software, data or information resource, data processing software, database, production service resource, service resource, software application, software resource, source code Automatic prediction tool to infer protein-protein interaction networks, it is applicable for lots of species using orthology and known interactions. The interoPORC method is based on the interolog concept and combines source interaction datasets from public databases as well as clusters of orthologous proteins (PORC) available on Integr8. Users can use this page to ask InteroPorc for all species present in Integr8. Some results are already computed and users can run InteroPorc to investigate any other species. Currently, the following databases are processed and merged (with datetime of the last available public release for each database used): IntAct, MINT, DIP, and Integr8. orthology, prediction, protein interaction, tool, sequenced genome, proteinprotein interaction, inferred interaction, molecular interaction, interaction, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Integr8 : Access to complete genomes and proteomes
is related to: IntAct
is related to: MINT
is related to: Database of Interacting Proteins (DIP)
is related to: PSICQUIC Registry
has parent organization: CEA; Gif sur Yvette; France
European Union FELICS 021902 RII3;
Marie Curie Fellowship ;
French National Agency of Research ANR Biosys06_134823 SULFIRHOM;
French Atomic Energy Commission
PMID:18508856 Open unspecified license, Acknowledgement requested nif-0000-20816, biotools:interoporc https://bio.tools/interoporc SCR_002067 InteroPorc: Automatic molecular interaction predictions, Automatic molecular interaction predictions 2026-08-29 11:21:10 6
Cscan
 
Resource Report
Resource Website
1+ mentions
Cscan (RRID:SCR_006756) Cscan analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Data resource that includes a large collection of genome-wide ChIP-Seq experiments performed on transcription factors (TFs), histone modifications, RNA polymerases and others. Enriched peak regions from the ChIP-Seq experiments are crossed with the genomic coordinates of a set of input genes, to identify which of the experiments present a statistically significant number of peaks within the input genes' loci. The input can be a cluster of co-expressed genes, or any other set of genes sharing a common regulatory profile. Users can thus single out which TFs are likely to be common regulators of the genes, and their respective correlations. Also, by examining results on promoter activation, transcription, histone modifications, polymerase binding and so on, users can investigate the effect of the TFs (activation or repression of transcription) as well as of the cell or tissue specificity of the genes' regulation and expression. regulator, gene, genome-wide chip-seq, chip-seq, gene, genome is listed by: OMICtools PMID:22669907 Free OMICS_00529 SCR_006756 2026-08-29 11:22:41 4
SCPD - Saccharomyces cerevisiae promoter database
 
Resource Report
Resource Website
10+ mentions
SCPD - Saccharomyces cerevisiae promoter database (RRID:SCR_004412) SCPD analysis service resource, data analysis service, data or information resource, data repository, database, production service resource, service resource, storage service resource A promoter database of Saccharomyces cerevisiae. Users can explore the promoter regions of ~6000 genes and ORFs in yeast genome, annotate putative regulatory sites of all genes and ORFs, locate intergenic regions, and retrieve sequence of the promoter region. In regards to regulatory elements and transcription factors, users can provide information on transcriptionally related genes, browse matrix and consensus sequences, view the correlation between elements, observe binding affinity and expression, and look at genomewise distribution. SCPD also provides some simple but useful tools for promoter sequence analysis. Gene, consensus and matrix records may be submitted. promoter, gene, genome, orf, transcription factor binding site, transcriptional start site, transcription factor is listed by: OMICtools
has parent organization: Cold Spring Harbor Laboratory
PMID:10487868 OMICS_01867, nif-0000-03445 SCR_004412 SCPD - The Promoter Database of Saccharomyces cerevisiae 2026-08-29 11:21:53 20
EGAN: Exploratory Gene Association Networks
 
Resource Report
Resource Website
1+ mentions
EGAN: Exploratory Gene Association Networks (RRID:SCR_008856) EGAN data analysis software, data processing software, software application, software resource Exploratory Gene Association Networks (EGAN) is a software tool that allows a bench biologist to visualize and interpret the results of high-throughput exploratory assays in an interactive hypergraph of genes, relationships (protein-protein interactions, literature co-occurrence, etc.) and meta-data (annotation, signaling pathways, etc.). EGAN provides comprehensive, automated calculation of meta-data coincidence (over-representation, enrichment) for user- and assay-defined gene lists, and provides direct links to web resources and literature (NCBI Entrez Gene, PubMed, KEGG, Gene Ontology, iHOP, Google, etc.). EGAN functions as a module for exploratory investigation of analysis results from multiple high-throughput assay technologies, including but not limited to: * Transcriptomics via expression microarrays or RNA-Seq * Genomics via SNP GWAS or array CGH * Proteomics via MS/MS peptide identifications * Epigenomics via DNA methylation, ChIP-on-Chip or ChIP-Seq * In-silico analysis of sequences or literature EGAN has been built using Cytoscape libraries for graph visualization and layout, and is comparable to DAVID, GSEA, Ingenuity IPA and Ariadne Pathway Studio. There are pre-collated EGAN networks available for human (Homo sapiens), mouse (Mus musculus), rat (Rattus norvegicus), chicken (Gallus gallus), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), nematode (Caenorhabditis elegans), mouse-ear cress (Arabidopsis thaliana), rice (Oryza sativa) and brewer's yeast (Saccharomyces cerevisiae). There is now an EGAN module available for GenePattern (human-only). Platform: Windows compatible, Mac OS X compatible, Linux compatible gene, gene association, network, protein-protein interaction, pathway, interaction, annotation, signaling pathway, enrichment, cytoscape, visualization is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: UCSF Helen Diller Family Comprehensive Cancer Center Biostatistics Core
NCI P30 CA92103 PMID:19933825 Free for academic use nlx_149222 SCR_008856 Exploratory Gene Association Networks, Exploratory Gene Association Networks (EGAN) 2026-08-29 11:23:14 8
GeneMerge
 
Resource Report
Resource Website
10+ mentions
GeneMerge (RRID:SCR_005744) GeneMerge analysis service resource, data analysis service, production service resource, service resource, software application, software resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Web-based and standalone application that returns a wide range of functional genomic data for a given set of study genes and provides rank scores for over-representation of particular functions or categories in the data. It uses the hypergeometric test statistic which returns statistically correct results for samples of all sizes and is the #2 fastest GO tool available (Khatri and Draghici, 2005). GeneMerge can be used with any discrete, locus-based annotation data, including, literature references, genetic interactions, mutant phenotypes as well as traditional Gene Ontology queries. GeneMerge is particularly useful for the analysis of microarray data and other large biological datasets. The big advantage of GeneMerge over other similar programs is that you are not limited to analyzing your data from the perspective of a pre-packaged set of gene-association data. You can download or create gene-association files to analyze your data from an unlimited number of perspectives. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, genomics, functional genomic data, analysis, post-genomic analysis, data mining, hypothesis testing, statistical analysis, slimmer-type tool, term enrichment, text mining, false discovery rate, bonferroni correction, false discovery rate and bonferroni correction, perl, microarray is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Harvard University; Cambridge; United States
PMID:12724301 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149203 http://genemerge.cbcb.umd.edu/ SCR_005744 2026-08-29 11:27:47 26

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