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http://www.scienceexchange.com/facilities/vib-compound-screening-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Compound screening facility that has several drug-like compound collections available that amount to a total of about 74,000 compounds and a human siRNA library that targets almost 8,000 genes. State-of-the-art liquid handling systems and detection technologies are available for screening in-house or custom collections in 96- or 384-well plate format. The platform is compatible with biochemical assays, cell-based assays in a broad range of cellular systems and assays in the model plant Arabidopsis thaliana. Its core activities consist of managing the VIB screening collections, assisting researchers in assay development / automation and performing high-throughput screenings. After hit clustering and selection, the VIB-CSF team can contribute in structure-activity analysis, IC50 measurements, cytotoxicity analysis, secondary screening for hit validation and counter screening for specificity analysis.

Proper citation: VIB Compound Screening Facility (RRID:SCR_012256) Copy   

•   Source: SciCrunch Registry

http://www.uottawa.ca/

University of Ottawa often referred to as uOttawa or U of O, is a bilingual public research university in Ottawa, Ontario, Canada.

Proper citation: University of Ottawa; Ontario; Canada (RRID:SCR_006319) Copy   

•   Source: SciCrunch Registry

https://vpixx.com/products/viewpixx-3d/

VIEWPixx /3D (VPixx Technologies) is a 1920x1080 resolution, 120 Hz, calibrated research-grade LCD monitor. It is designed for stereoscopic (3D) stimulus presentation and other high-dynamic vision-science paradigms where deterministic timing and synchronized I/O are critical. It pairs fast-response industrial TN LCD glass with a custom VPixx panel/video controller and a scanning direct-RGB LED backlight engineered to reduce motion artifacts/ghosting/crosstalk, and to improve spatial uniformity, while bypassing consumer “enhancement” processing for predictable experimental output. For stereoscopic workflows, VIEWPixx /3D supports 120 Hz frame-sequential 3D (60 Hz/eye) when used with 3DPixx active shutter glasses (RF emitter + glasses kit), and it can provide a dual-link DVI console output to mirror the participant's view without adding GPU load. The system is also a synchronized display + acquisition toolbox: integrated button-box interface, 24-channel TTL triggers, stereo audio I/O, and a full analog I/O subsystem are implemented on the same board as video control to enable microsecond-precision synchronization to video refresh—useful for EEG triggers, reaction-time tasks, and other timing-sensitive paradigms.In terms of bit depth, the VIEWPixx /3D is native 8 bits per colour, with support fot 10-bit resolution per RGB channel via custom video modes.

Proper citation: VPixx: VIEWPixx /3D (RRID:SCR_009646) Copy   

•   Source: SciCrunch Registry

https://www.foundationmedicine.com/

American company based in Cambridge, Massachusetts, which develops, manufactures, and sells genomic profiling assays based on next-generation sequencing technology for solid tumors, hematologic malignancies, and sarcomas. Specializes in precision medicine. FMI routinely analyzes cancer specimens using advanced sequencing technology of FoundationOne to profile tumor genomics.

Proper citation: Foundation Medicine (RRID:SCR_025628) Copy   

•   Source: SciCrunch Registry

https://sysmex-inostics.com/

Biotechnology company in Baltimore, Maryland, specializing in liquid biopsy. Offers comprehensive NGS testing services for clinical trials, enhancing oncology drug development and patient outcomes.

Proper citation: Sysmex Inostics (RRID:SCR_025629) Copy   

•   Source: SciCrunch Registry

https://www.aacr.org/

Cancer research organization dedicated to accelerating the conquest of cancer. The mission is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research. Through its programs and services, the AACR fosters research in cancer and related biomedical science, accelerates dissemination of new research findings, promotes science education and training, and advances the understanding of cancer etiology, prevention, diagnosis, and treatment throughout the world.

Proper citation: American Association for Cancer Research (RRID:SCR_025561) Copy   

•   Source: SciCrunch Registry

https://www.accord-healthcare.com:2053/

Global pharmaceutical company that develops, manufactures and distributes essential medicines for hospitals and retail pharmacies.

Proper citation: Accord (RRID:SCR_025575) Copy   

•   Source: SciCrunch Registry

https://www.petermac.org/

Australian oncology research institute, cancer treatment and professional oncologist training centre located in Melbourne, Victoria.

Proper citation: Peter MacCallum Cancer Institute (RRID:SCR_025611) Copy   

•   Source: SciCrunch Registry

https://www.licor.com/bio/odyssey-m/

Imager has multiple detection modes with up to 19 fluorescent and luminescent channel combinations to power wide range of assays including 3-Color Quantitative Western Blots, 3-Color In-Cell Western Assays, Cell Analysis Studies, ELISA, Tissue Section Imaging, Viral Titration Assays. Imager includes sCMOS image sensor and 5-micron resolution.

Proper citation: LI-COR: ODYSSEY M Imaging System (RRID:SCR_025709) Copy   

•   Source: SciCrunch Registry

https://owncloud.com

Open-source software project for content collaboration and sharing and syncing of files in distributed and federated enterprise scenarios. Used for file synchronization and sharing of data. Platform that allows users to securely store, access, and manage files from anywhere, on any device. Designed for privacy and control, it offers customizable storage solutions, collaboration tools, and integrations, making it ideal for businesses and individuals seeking secure, self-hosted alternative to traditional cloud services.

Proper citation: ownCloud (RRID:SCR_025669) Copy   

•   Source: SciCrunch Registry

https://www.cytivalifesciences.com/en/us/shop/protein-analysis/molecular-imaging-for-proteins/imaging-systems/amersham-typhoon-gel-and-blot-imaging-systems-p-00192

Laser scanner with exceptional data quality through extremely sensitive detection, high image resolution, and very broad linear dynamic range. Amersham Typhoon 5 model offers five-laser configuration option with advanced photomultiplier tubes. Has the same capabilities as Amersham Typhoon RGB model, with the addition of near-infrared (NIR) functionality.

Proper citation: Cytiva: Amersham Typhoon 5 (RRID:SCR_025702) Copy   

•   Source: SciCrunch Registry

https://www.beckman.com/centrifuges/ultracentrifuges/optima-max-xp/393315

Benchtop ultracentrifuge with separations for volumes as low as 175 ul, touch screen navigation, speeds up to 150,000 RPM, and RCF capability of up to 1019000 x g.

Proper citation: Beckman Coulter: Optima Max-XP Tabletop Ultracentrifuge (RRID:SCR_025704) Copy   

•   Source: SciCrunch Registry

https://nanotempertech.com/prometheus/

Instrument that uses nanoDSF to analyze protein folding and stability. Provides precise stability data across multiple parameters to characterize thermal unfolding, particle sizing, and aggregation of proteins. Used in variety of applications, including protein engineering, membrane protein research, formulation development, and quality control.

Proper citation: Oxford: Nanopore Technologies: Prometheus (RRID:SCR_025758) Copy   

•   Source: SciCrunch Registry

https://mass-spec.stanford.edu/about/instruments

Bruker timsTOF Ultra boasts increased sensitivity and resolution whilst allowing for exceptionally low sample input and resolution whilst allowing for exceptionally low sample input.

Proper citation: Stanford Bruker timsTOF Ultra nanoLC/MS (RRID:SCR_025639) Copy   

•   Source: SciCrunch Registry

https://missionbio.com/wp-content/uploads/2023/08/Tapestri-Single-Cell-DNA-Sequencing-v3-User-Guide_MB05-0017.pdf

Tapestri single-cell DNA sequencing platform provides both genotype and phenotype data from the same cell. Platform consists of instrument, DNA cartridge, which represents microfluidics device, and reagents. Cartridge is equipped with reservoirs that are used to load reagents required for automated cell processing. Pressure supplied by instrument drives reagents from reservoirs through microfluidic device and out to PCR collection tubes that are mounted below cartridge. Cartridge and tubes can be loaded and unloaded from instrument and disposed of after completion of workflow. User interacts with instrument via touch screen interface, which can be used to select programs, monitor status of running programs, and more.

Proper citation: Mission Bio: Tapestri Platform (RRID:SCR_025736) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/order/catalog/product/A52864?SID=srch-srp-A52864

PCR System is plate based digital PCR platform powered by proprietary microfluidic array plate technology that enables all necessary steps for dPCR including compartmentalizing, thermal cycling and data acquisition to be conducted on single instrument. Uses nucleic acid quantification technique that allows absolute quantification without the need for standard curves. Bulk reaction mix is distributed or digitized into thousands of small independent reactions so that each micro-chamber contains either one or zero copies of the target. Statistical methods are then used to calculate the original concentrations based on the number of positive and negative micro-chambers.

Proper citation: Thermo Fisher: Applied Biosystems: QuantStudio Absolute Q Digital PCR System (RRID:SCR_025737) Copy   

•   Source: SciCrunch Registry

https://ipfs.tech/

Open system to manage data without central server. Peer-to-peer content delivery network built around the content addressing: store, retrieve, and locate data based on fingerprint of its actual content rather than its name or location.

Proper citation: InterPlanetary File System (RRID:SCR_025685) Copy   

•   Source: SciCrunch Registry

https://www.thermofisher.com/es/es/home/industrial/chromatography/liquid-chromatography-lc/hplc-uhplc-systems/vanquish-horizon-uhplc-system.html

System for applications requiring high-quality Ultra High Performance Liquid Chromatography. Uses high pressure to separate and identify components of mixture. Provides accurate separation, retention times, peak area, detector sensitivity and reduced baseline noise for high flow rates.

Proper citation: Thermo Fisher: Vanquish Horizon UHPLC System (RRID:SCR_025713) Copy   

•   Source: SciCrunch Registry

https://tracedrawer.com/product/tracedrawer/

Software for evaluating, comparing and presenting real-time interaction data. Used for quantification of kinetics and affinity through curve fitting, with large number of binding models to choose from. Can extract experimental information from measurement, requiring minimal user input.

Proper citation: TraceDrawer (RRID:SCR_025782) Copy   

•   Source: SciCrunch Registry

https://umaine.edu/

Public land-grant research university in Orono, Maine. It was established in 1865 as the land-grant college of Maine and is the flagship university of the University of Maine System.

Proper citation: University of Maine; Orono; United States (RRID:SCR_025786) Copy   

•   Source: SciCrunch Registry