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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CellProfiler Image Analysis Software
 
Resource Report
Resource Website
1000+ mentions
CellProfiler Image Analysis Software (RRID:SCR_007358) software application, image analysis software, software resource, data processing software Software tool to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically. It counts cells and also measures the size, shape, intensity and texture of every cell (and every labeled subcellular compartment) in every image. It was designed for high throughput screening but can perform automated image analysis for images from time-lapse movies and low-throughput experiments. CellProfiler has an increasing number of algorithms to identify and measure properties of neuronal cell types. high-throughput, high content imaging, software, image, cell, phenotype, measurement, subcellular, intensity, size, shape, analysis, algorithm is listed by: Debian
is related to: CellProfiler Analyst
has parent organization: Broad Institute
NIGMS R01 GM089652;
NIGMS RC2 GM092519;
NHGRI RL1 HG004671
PMID:21349861
PMID:17076895
PMID:19014601
PMID:19188593
Free, Available for download, Freely available SCR_010649, nlx_66812, nif-0000-00280 https://sources.debian.org/src/cellprofiler/ SCR_007358 Cell Profiler, CellProfiler - cell image analysis software 2026-07-28 09:41:45 3265
GENCODE
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
GENCODE (RRID:SCR_014966) project portal, data or information resource, portal, dataset Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation. human, mouse, genome, annotation, sequence, gene features, bio.tools is listed by: Debian
is listed by: bio.tools
is affiliated with: ENCODE
NHGRI 5U54HG004555;
Wellcome Trust WT098051
PMID:22955987 Free biotools:GENCODE https://bio.tools/GENCODE SCR_014966 ENCODE 2026-07-28 09:43:38 7700
ProteomeTools
 
Resource Report
Resource Website
10+ mentions
ProteomeTools (RRID:SCR_018535) project portal, data or information resource, portal Project for building molecular and digital tools from human proteome to facilitate biomedical research, drug discovery, personalized medicine and life science research. Molecular tool, human proteome, proteome, human, peptide, data is related to: ProteomicsDB
is related to: ProteomeXchange
German Federal Ministry of Education and Research ;
Alexander von Humboldt Foundation ;
American Recovery and Reinvestment Act ;
NHGRI RC2 HG005805;
NIGMS R01 GM087221;
NCRR S10 RR027584;
NIGMS P50 GM076547;
European Research Council ;
Swiss National Science Foundation
PMID:28135259 Free, Freely available http://www.proteometools.org SCR_018535 2026-07-28 09:44:46 21
GeneTests
 
Resource Report
Resource Website
10+ mentions
GeneTests (RRID:SCR_010725) GeneTests service resource, biomaterial analysis service, narrative resource, data or information resource, database, production service resource, material analysis service, analysis service resource, topical portal, portal, training material The GeneTests Web site, a publicly funded medical genetics information resource developed for physicians, other healthcare providers, and researchers, is available at no cost to all interested persons. By providing current, authoritative information on genetic testing and its use in diagnosis, management, and genetic counseling, GeneTests promotes the appropriate use of genetic services in patient care and personal decision making. At This Site: * GeneReviews: Expert-authored peer-reviewed disease descriptions * Laboratory Directory: International directory of genetic testing laboratories * Clinic Directory: International directory of genetics and prenatal diagnosis clinics * Educational Materials: Illustrated glossary, information on genetic services, PowerPoint presentations, annotated Internet resources We comply with the HONcode standard for trustworthy health information. has parent organization: University of Washington; Seattle; USA
has parent organization: NCBI
NCI ;
NHGRI 1 P41 LM/HG 06029;
NLM 1 P41 LM/HG 06029;
NLM contract N01-LM-4-3505;
NLM 5 P41 LM07242;
NLM 2 P41 LM 06001;
DOE DE-FG03-02ER63301/A00
nlx_94696 SCR_010725 GeneTests: Clinical Genetic Information Resource 2026-07-28 09:42:58 12
MACS
 
Resource Report
Resource Website
1000+ mentions
MACS (RRID:SCR_013291) MACS software application, software resource, data analysis software, data processing software Software Python package for identifying transcript factor binding sites. Used to evaluate significance of enriched ChIP regions. Improves spatial resolution of binding sites through combining information of both sequencing tag position and orientation. Can be used for ChIP-Seq data alone, or with control sample with increase of specificity. identify, transcript, factor, binding, site, model, based, analysis, CHIP Seq, short, read, sequencer, protein, DNA, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Dana-Farber Cancer Institute
NHGRI HG004069;
NHGRI HG004270;
NIDDK DK074967
PMID:18798982
DOI:10.1186/gb-2008-9-9-r137
Free, Available for download, Freely available OMICS_00446, biotools:macs https://bio.tools/macs, https://sources.debian.org/src/macs/ SCR_013291 MACS - Model-based Analysis for ChIP-Seq, Model-based Analysis for ChIP-Seq, MACS2 2026-07-28 09:43:12 1325
Bamtools
 
Resource Report
Resource Website
100+ mentions
Bamtools (RRID:SCR_015987) software application, data analysis software, software resource, data management software, data processing software, software toolkit Software that provides both a C++ API and a command-line toolkit for reading, writing, and manipulating genome sequence alignment files in the BAM and SAM formats. It is used for research analysis and management of data produced by sequencing technologies. c++, api, sam, bam genome, sequence, alignment, data, analysis, management, command, manipulation, binary, map, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG004719;
NHGRI RC2 HG005552
PMID:21493652
DOI:10.1093/bioinformatics/btr174
biotools:bamtools, OMICS_11315 https://bio.tools/bamtools, https://sources.debian.org/src/bamtools/ SCR_015987 API:Application Programming Interface, BAM:Binary Alignment Map, SAM:Sequence Alignment Map 2026-07-28 09:44:11 324
Blixem
 
Resource Report
Resource Website
1+ mentions
Blixem (RRID:SCR_015994) software application, software resource, data processing software, alignment software, image analysis software Software for sequence alignments that displays multiple match sequences aligned against a single genomic reference sequence. It can be used for manipulation, display and annotation of genomic data, to check the quality of an alignment, to find missing/misaligned sequence, and to identify splice sites and polyA sites. software, sequence, alignment, annotation, genomic, reference, data, display, manipulation, DNA is related to: SEQtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust Grant 098051;
NHGRI U54 HG00455
PMID:26801397 Free, Available for download SCR_015994 SEQtools Blixem 2026-07-28 09:44:02 2
AMAP
 
Resource Report
Resource Website
100+ mentions
AMAP (RRID:SCR_015969) software application, source code, software resource, data processing software, alignment software, image analysis software Source code that performs multiple alignment of peptidic sequences. It utilizes posterior decoding and a sequence-annealing alignment, instead of the traditional progressive alignment method. software, peptide, sequence, alignment, annealing, bioinformatics, multiple, svn, posterior, decoding is listed by: Debian
is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
NSF EF 03-31494;
NHGRI R01 HG2362;
NSF CCF0347992
PMID:17237099
DOI:10.1093/bioinformatics/btl311
Free, Available for download OMICS_19787 http://baboon.math.berkeley.edu/amap/, https://sources.debian.org/src/amap-align/ https://sources.debian.org/src/amos-assembler/ SCR_015969 amap-align 2026-07-28 09:44:01 388
Poretools
 
Resource Report
Resource Website
50+ mentions
Poretools (RRID:SCR_015879) software application, data analysis software, sequence analysis software, software resource, data processing software, software toolkit Software toolkit for analyzing nanopore sequence data. nanopore, sequence, python, oxford nanopore, MinION, quality control, downstream analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
Medical Research Council ;
NHGRI R01 HG006693
PMID:25143291 Open source, Free, Available for download biotools:poretools https://bio.tools/poretools SCR_015879 2026-07-28 09:44:10 81
fermi-lite
 
Resource Report
Resource Website
1+ mentions
fermi-lite (RRID:SCR_016112) software application, algorithm resource, software resource, data processing software, alignment software, standalone software, image analysis software Standalone C library as well as a command-line tool for assembling Illumina short reads in small regions. It is an overlap-based assembler used in sequencing to retain heterozygous events and to assemble diploid regions for the purpose of variant calling. assembling, short, read, small, region, sequencing, retain, heterozygous, event, diploid, variant, calling is related to: Illumina NHGRI U54 HG003037;
NIGMS GM100233
PMID:26220959 Free, Available for download SCR_016112 FermiKit, Fml-asm 2026-07-28 09:44:05 4
AbundantOTU+
 
Resource Report
Resource Website
1+ mentions
AbundantOTU+ (RRID:SCR_016527) AbundantOTU software application, data analysis software, sequence analysis software, software resource, data processing software Software tool for analysis of large 16S rRNA pyrosequences by using a consensus alignment algorithm, utilizing the sequence redundancy of abundant species in the pyrosequence dataset. pyrosequencing, 16S, rRNA, gene, operational, taxonomic, unit, abundant, species, dataset is listed by: OMICtools
has parent organization: Indiana University; Indiana; USA
NHGRI R01 HG004908;
NHLBI U01 HL09896001
PMID:22102981 Free, Available for download, Freely available SCR_016527 AbundantOTU:Abundant Operational Taxonomic Unit, Abundant OTU, AbundantOTU+ 2026-07-28 09:44:16 1
Reactome Knowledgebase
 
Resource Report
Resource Website
100+ mentions
Reactome Knowledgebase (RRID:SCR_023504) data or information resource, database, data access protocol, software resource, web service Open source relational database of signaling and metabolic molecules and their relations organized into biological pathways and processes. Core unit of Reactome data model is the reaction. Entities (nucleic acids, proteins, complexes, vaccines, anti-cancer therapeutics and small molecules) participating in reactions form network of biological interactions and are grouped into pathways including classical intermediary metabolism, signaling, transcriptional regulation, apoptosis and disease. External domain expert provides expertise, curator formalizes it into database structure, and external domain expert reviews representation. System of evidence tracking ensures that all assertions are backed up by primary literature. Website is designed to give the user graphical map of known biological processes and pathways that is also an interface. Database and website enable to find, organize, and utilize biological information to support data visualization, integration and analysis. signaling and metabolic molecules relations, biological pathways and processes, intermediary metabolism, signaling, transcriptional regulation, apoptosis, disease NHGRI U24 HG012198 Free, Freely available SCR_023504 Reactome 2026-07-28 09:45:56 445
Michigan Imputation Server
 
Resource Report
Resource Website
1+ mentions
Michigan Imputation Server (RRID:SCR_023554) software resource, data access protocol, web service Web based service for imputation that facilitates access to new reference panels and improves user experience and productivity. Server implements whole genotype imputation workflow using MapReduce programming model for efficient parallelization of computationally intensive tasks. Genotype imputation service using Minimac4. Genotype imputation, whole genotype imputation workflow, parallelization of computationally intensive tasks, is related to: MINIMAC NHGRI HG007022;
NHLBI HL117626;
NHGRI HG000376;
NIDA R01DA037904;
Austrian Science Fund ;
European Community Seventh Framework Programme ;
NIA
PMID:27571263 Free, Freely available https://github.com/genepi/imputationserver SCR_023554 2026-07-28 09:45:56 8
Hetnet Connectivity Search
 
Resource Report
Resource Website
1+ mentions
Hetnet Connectivity Search (RRID:SCR_023630) Hetnet software resource, data access protocol, web service Web app that allows users to search for the most important paths connecting any two nodes in Hetionet. Hetionet, paths connection, paths search, paths connecting any two nodes in Hetionet, Pfizer Inc ;
NHGRI T32 HG000046;
NHGRI R01 HG010067;
NCI R01 CA237170;
Gordon and Betty Moore Foundation
PMID:36711546 Free, Freely available SCR_023630 , Heterogeneous network Connectivity Search, heterogeneous network 2026-07-28 09:45:59 1
eXpress
 
Resource Report
Resource Website
100+ mentions
eXpress (RRID:SCR_006873) eXpress software application, data analysis software, sequence analysis software, software resource, data processing software THIS RESOURCE IS NO LONGER IN SERVICE. Documented January 29, 2018.
From website: "Note that the eXpress software is also no longer being developed. We recommend you use kallisto instead." Kallisto can be found at http://pachterlab.github.io/kallisto/.

Software for streaming quantification for high-throughput DNA/RNA sequencing.
Can be used in any application where abundances of target sequences need to be estimated from short reads sequenced from them.
quantification, high-throughput, DNA, RNA, sequencing, target, fragment, analysis is listed by: OMICtools
is listed by: Debian
has parent organization: University of California at Berkeley; Berkeley; USA
NSF ;
NHGRI R01HG006129
DOI:10.1038/nmeth.2251 THIS RESOURCE IS NO LONGER IN SERVICE SCR_015990, OMICS_01275 https://sources.debian.org/src/berkeley-express/ SCR_006873 eXpress - Streaming quantification for high-throughput sequencing, Berkeley-express 2026-07-28 09:41:44 494
LINCS Project
 
Resource Report
Resource Website
10+ mentions
LINCS Project (RRID:SCR_016486) LINCS data or information resource, organization portal, project portal, database, consortium, portal Project to create network based understanding of biology by cataloging changes in gene expression and other cellular processes when cells are exposed to genetic and environmental stressors. Program to develop therapies that might restore pathways and networks to their normal states. Has LINCS Data Coordination and Integration Center and six Data and Signature Generation Centers: Drug Toxicity Signature Generation Center, HMS LINCS Center, LINCS Center for Transcriptomics, LINCS Proteomic Characterization Center for Signaling and Epigenetics, MEP LINCS Center, and NeuroLINCS Center. data integration, network biology, gene expression, L1000, MCF10A, MEMA, P100, LINCS program, LINCS project, systems biology, systems pharmacology, FASEB list is related to: Drug Gene Budger
is related to: LINCS Joint Project - Breast Cancer Network Browser
is related to: piNET
cancer, heart disease, neurodegenerative disorder NIH Common Fund ;
NHLBI U54 HL127624;
NHLBI U54 HL127366;
NHLBI U54 HL127365;
NHGRI U54 HG008100;
NHGRI U54 HG008097;
NHGRI U54 HG008098;
NINDS U54 NS091046
PMID:29199020 Free, Freely available SCR_016487 SCR_016486 LINCS, Library of Integrated Network based Cellular Signatures, LINCS Program 2026-07-28 09:44:19 43
biobakery
 
Resource Report
Resource Website
10+ mentions
biobakery (RRID:SCR_016596) software application, data analysis software, software resource, data processing software, software toolkit Analysis environment and collection of individual software tools to process raw shotgun metagenome or metatranscriptome sequencing data for quantitative microbial community profiling. Used for a metaomics data analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Huttenhower lab, metaomics, data, analysis, process, raw, shotgun, metagenome, metatranscriptome, sequencing, microbial, profiling, bio.tools is used by: Nephele
is listed by: Debian
is listed by: bio.tools
is related to: Human Microbiome Project
has parent organization: Harvard University; Cambridge; United States
NIDDK U54 DE023798;
Sloan Foundation 4406J0B;
NHGRI R01 HG005220;
NSF DBI1053486;
NHGRI R01 HG005969;
ARO W911NF1110473
PMID:29194469 THIS RESOURCE IS NO LONGER IN SERVICE biotools:biobakery http://huttenhower.sph.harvard.edu/biobakery, https://bio.tools/biobakery SCR_016596 bioBakery, biobakery 2026-07-28 09:44:18 13
Discovar assembler
 
Resource Report
Resource Website
10+ mentions
Discovar assembler (RRID:SCR_016755) Discovar software application, data analysis software, sequence analysis software, software resource, data processing software Software tool for variant calling with reference and de novo assembly of genomes. The heart of DISCOVAR is a de novo genome assembler which can generate de novo assemblies for both large and small genomes. variant, calling, reference, de novo, assembly, genome, genetic, human, sequence, analysis is listed by: OMICtools
has parent organization: Broad Institute
NHGRI R01 HG003474;
NHGRI U54 HG003067;
NIAID HHSN272200900018C
PMID:25326702 Free, Available for download, Freely available SCR_016755 Discovar de novo, Discovar 2026-07-28 09:44:26 20
PathwayMatcher
 
Resource Report
Resource Website
1+ mentions
PathwayMatcher (RRID:SCR_016759) software application, data analysis software, software resource, data processing software, network analysis software Software tool for multi omics pathway mapping and proteoform network generation. Open source software writen in Java to search for pathways related to a list of proteins in Reactome. mapping, omics, data, pathways, network, analysis, proteoform, generate, Reactome, database, match, bio.tools is listed by: Galaxy
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
works with: Reactome
European Research Council ;
Research Council of Norway ;
Bergen Research Foundation ;
NIGMS U54 GM114833;
NHGRI U41 HG003751
DOI:10.1101/375097 Free, Available for download, Freely available BioTools:PathwayMatcher, biotools:PathwayMatcher https://anaconda.org/bioconda/pathwaymatcher, https://toolshed.g2.bx.psu.edu/repository?repository_id=6d75f02b86acc421, https://bio.tools/PathwayMatcher, https://bio.tools/PathwayMatcher, https://bio.tools/PathwayMatcher SCR_016759 2026-07-28 09:44:26 1
GenomicFeatures
 
Resource Report
Resource Website
50+ mentions
GenomicFeatures (RRID:SCR_016960) software application, data analysis software, software resource, data processing software, software toolkit Software R package for making and manipulating transcript centric annotations. Used to download the genomic locations of the transcripts, exons and cds of a given organism, from either the UCSC Genome Browser or a BioMart database. making, manipulating, transcript, centric, annotation, genomic, location, exon, cds, bio.tools is used by: riboWaltz
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
NHGRI P41 HG004059;
NHGRI U41 HG004059;
NHLBI R01 HL086601;
NHLBI R01 HL093076;
NHLBI R01 HL094635
PMID:23950696 Free, Available for download, Freely available biotools:genomicfeatures https://bio.tools/genomicfeatures SCR_016960 2026-07-28 09:44:30 65

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