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https://www.colorado.edu/chbe/instrument-shop

Provides mechanical and electrical design and fabrication services at CU Boulder.Provides solutions for instructional and research needs for any department or college. Collectively comprised of machine shop and electronics shop, both of which are located in basement level of Jennie Smoly Caruthers Biotechnology Building.

Proper citation: University of Colorado Boulder Chemical and Bio. Engineering instrument and electronics Core Facility (RRID:SCR_019298) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/applied-bioinformatics-laboratories

Core provides computational analysis for high throughput genomic data, including but not limited to, next generation sequencing data. Our mission is to accelerate scientific discoveries by guiding experimental design, performing robust data quality assessment, and carrying out comprehensive computational analyses. Registration to iLab required.

Proper citation: New York University Grossman School of Medicine Applied Bioinformatics Laboratories Facility (RRID:SCR_019178) Copy   

•   Source: SciCrunch Registry

https://www.boisestate.edu/brc/home/

Designed to provide supportive environment for interdisciplinary research and education with opportunities for students and faculty members alike with focus on biomolecules study with emphasis on proteins and protein interactions. Provides instrumentation and facilities for characterization of biomolecules and their role in variety of biomedical and environmental processes. Partnerships between Center and Idaho-BRIN/INBRE, UI, ISU, Boise VA Medical Center, College of Idaho, and Northwest Nazarene University. BRC provides seminars, training workshops, and other networking opportunities.

Proper citation: Boise State University Biomolecular Research Center Core Facility (RRID:SCR_019174) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/medicine/research/corefacilities/transgenic-facility/index.html

Core provides mouse transgenic and cryopreservation services including Sperm cryopreservation, Mouse in vitro fertilization, Mouse Rederivation, Transgenic Mouse Generation,DNA microinjection,CRISPR/Cas9-Mediated Genetically Engineered Mouse Production. Core equipment includes Hamilton Thorne Computer-Aided Sperm Analysis System,Sutter Xenoworks Micromanipulator,Sutter Xenoworks Digital Microinjector,Nikon TE2000 inverted microscope,MINC benchtop incubator,Leica M165 dissecting microscope.

Proper citation: University of Alberta Faculty of Medicine and Dentistry Transgenic Core Facility (RRID:SCR_019175) Copy   

•   Source: SciCrunch Registry

https://www.unh.edu/research/welcome-university-instrumentation-center

University wide core facility offers NMR,SEM including FIB, EBS, EBSD, Tensile Stage,Confocal,X-Ray Photoelectron Spectroscopy,X-Ray Microscope aka Micro CT, Expert analysis of research and industrial samples,Training in scientific instrument operation and data analysis, Maintenance, repair, and calibration of instruments,Specialty instrument engineering design and application services,Facilitation of access to scientific instruments throughout the university.

Proper citation: University of New Hampshire University Instrumentation Center Core Facility (RRID:SCR_021101) Copy   

•   Source: SciCrunch Registry

https://www.lsi.umich.edu/science/centers-technologies/center-structural-biology

Comprehensive structural biology resource.Provides high throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, and X-ray facility with access to high energy synchrotron radiation. Provides expert guidance to researchers through every stage of project, collaborating and consulting with researchers who use the facilities. Service categories are Chemical, Material and Protein Characterization, Molecular Biology. Services include Cloning, Crystallization, Differential thermal analysis, Drug development, NMR (small molecule), PCR, Protein crystallography, Protein engineering, Protein production, Structure determination, Xray.

Proper citation: University of Michigan Center for Structural Biology Core Facility (RRID:SCR_021065) Copy   

•   Source: SciCrunch Registry

https://cami.northwestern.edu/

Provides access to range of preclinical imaging modalities and support services. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture. Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis. Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.

Proper citation: Northwestern University Center for Advanced Molecular Imaging Core Facility (RRID:SCR_021192) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/zebrafish/

Provides Penn State research community with modern, centralized facility for housing, breeding and performing experiments with zebrafish.Provides physical and intellectual infrastructure for investigators whose research can benefit from use of zebrafish as model system.

Proper citation: Penn State Hershey College of Medicine Zebrafish Functional Genomics Core Facility (RRID:SCR_021199) Copy   

•   Source: SciCrunch Registry

https://www.etsu.edu/com/mbcf/

Core provides Genomics, Transcriptomics and Proteomics Services to researchers.

Proper citation: East Tennessee State University Quillen College of Medicine Molecular Biology Core Facility (RRID:SCR_021106) Copy   

•   Source: SciCrunch Registry

https://www.coresri.org/facilities?facility_id=16

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Core offers contemporary imaging, molecular biology, histology, flow cytometry, cell sorting, and real-time gene expression. Provides technologies and training including specialized microscope facility.

Proper citation: Brown Alpert Medical School Women and Infants Hospital of Rhode Island Kilguss Research Institute Molecular Biology and Imaging Core Facility (RRID:SCR_021348) Copy   

•   Source: SciCrunch Registry

https://www.wadsworth.org/research/cores/alm

Core facility is designed for Imaging living cells or tissues, Fluorescence imaging, Image analysis. Provides imaging of adherent cells or tissue fragments,drug delivery using perfusion chamber, gas exchange for the growth media, Rose chambers for imaging, image processing and analysis software to assist in data analysis and interpretation.

Proper citation: New York State Department of Health Wadsworth Center Advanced Light Microscopy and Image Analysis Core Facility (RRID:SCR_021104) Copy   

•   Source: SciCrunch Registry

https://psxl.ku.edu/

Core laboratory with infrastructure and expertise to perform all aspects of protein and small molecule structure determination using X-ray crystallography. For protein structure determination, high-throughput methods are utilized to move projects rapidly from gene-to-structure.

Proper citation: University of Kansas Lawrence Protein Structure and X-ray Crystallography Laboratory Core Facility (RRID:SCR_021742) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/proteomics-metabolomics-facility

Facility provides diverse range of Mass Spectrometry based proteomics and metabolomics services.Services include sample preparation, sample analysis, and data interpretation.

Proper citation: Cornell University BRC Proteomics and Metabolomics Core Facility (RRID:SCR_021743) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/epigenomics-facility

Provides service that maps protein DNA interactions genome wide, tracks experimental metadata, and implements quality controlled data processing and research based analysis pipelines. Provides epigenomic and bioinformatic research resources and services that include sample preparation services and data generation. Open source platforms enable and reinforce FAIR data practices. Core is able to receive and process cell and tissue samples for various diagnostic epigenetic assays.

Proper citation: Cornell University BRC Epigenomics Core Facility (RRID:SCR_021287) Copy   

•   Source: SciCrunch Registry

https://nuance.northwestern.edu/facilities/biocryo/index.html

Provides source for characterization of biological, soft matter, and hybrid samples with TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and STEM (Scanning Transmission Electron Microscopy) at cryogenic or at ambient temperature.Provide expertise and access to equipment for cryofixation and processing of frozen hydrated samples by high pressure freezing, plunge freezing, freeze fracturing, cryo ultramicrotomy, freeze substitution, and turbo freeze-drying. Conventional samples can be processed at ambient temperature with chemical fixation, dehydration, and resin embedding, or critical point drying. Offers EDX (Energy Dispersive X-ray Spectroscopy) for elemental analysis.Offers training on instruments and sample preparation techniques.BioCryo staff mentors new users, advises on experimental design, and collaborates with researchers in experiments with challenging and unconventional samples.BioCryo Facility participates in numerous educational and outreach events, e.g. workshops, seminars, demos, and facility tours.

Proper citation: Northwestern University NUANCE BioCryo Core Facility (RRID:SCR_021288) Copy   

•   Source: SciCrunch Registry

http://web.ncifcrf.gov/atp/default.asp?LabID=12&page=labs

Comprises six service groups. Our services are available to all NIH intramural researchers, and by interagency agreements to FDA and US Army at Ft. Detrick. We are happy to consult and distribute materials to not-for-profit institutions.Clone Optimization service include DNA cloning for protein expression; Gateway-based; fluorescent, epitope, solubility, purification tags; mutagenesis; vectors for insect/ baculovirus, mammalian, E. coli, P. pastoris, K. lactis. Microbial Expression: E. coli, P. pastoris, K. lactis, 2 mL to 60 L, autoinduction and IPTG; fully instrumented fermenters.Eukaryotic Expression service include insect / baculovirus, mammalian transient and stable, monoclonal antibodies.Protein Purification service include parallel microscale for process development; affinity and native, tag and endotoxin removal; scale-up to low gram scale.Virus Technology service include custom and stock adenovirus and lentivirus production; titer determination; promoter and reporter panels in lentivirus ready to deliver.Molecular Detection: qPCR and ELISA assaysdeveloped and executed, focused on human viruses in human samples; qPCR assays for mycoplasma and human pathogenic viruses contaminating cell lines; cell line identity testing.

Proper citation: Frederick National Laboratory Protein Expression Laboratory Core Facility (RRID:SCR_021286) Copy   

•   Source: SciCrunch Registry

https://strucbiol.pbsci.ucsc.edu/

Provides instrumentation, supplies, and expertise to assist researchers in structural characterization of biological macromolecules. Resources are available for crystallization and structure determination as wells as biophysical characterization of macromolecular stability and interactions.

Proper citation: University of California Santa Cruz Macromolecular Structure Function Core Facility (RRID:SCR_021283) Copy   

•   Source: SciCrunch Registry

http://www.nersc.gov

Supercomputer user facility operated by Lawrence Berkeley National Laboratory for the United States Department of Energy Office of Science.Houses high performance computing and data systems used by scientists at national laboratories and universities around the country.

Proper citation: University of California at Berkeley National Energy Research Scientific Computing Core Facility (RRID:SCR_021318) Copy   

•   Source: SciCrunch Registry

https://gladstone.org/science/flow-cytometry-core

Core offers operation, training and consultation on both cell sorters and analyzers.Our core comprises BDFACsAria II, two BDFACSAria Fusions, Fortessa X-20 and Attune, with analyzing and sorting up to 18 colors possible. Core also offers antibody staining, protocol optimization and data analysis services.

Proper citation: Gladstone Institutes Gladstone Flow Cytometry Core Facility (RRID:SCR_021714) Copy   

•   Source: SciCrunch Registry

https://biotech.unl.edu/proteomics-and-metabolomics#tab1

Provides services using mass spectrometry, including identification and relative quantification of proteins and several advanced methods for profiling and quantitation of small molecules.Provides outreach and education program including workshops,seminars and courses.Proteomics services include Bottom-up Proteomics of whole organisms, organs, organelles, tissues, cell pellets, pulldowns, complex or single protein mixes from solutions or gels;Quantification by label-free or multiplexed labeling techniques with microscale subfractionation to increase coverage;Post Translational Modification Characterization especially phosphopeptide enrichment from whole organism digests, but also ubiquitylation, acetylation, etc.Metabolomics services include Untargeted Quantification of small molecules;Primary metabolism using GC-MS and NIST/Fiehn Libraries;Secondary metabolism using LC-MS and Progenesis QI, NIST Library, mzCloud;Targeted Quantification using HPLC or LCMS.

Proper citation: University of Nebraska Lincoln Nebraska Center for Biotechnology Proteomics and Metabolomics Core Facility (RRID:SCR_021314) Copy   

•   Source: SciCrunch Registry