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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_A5LW
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Proper citation: RRID:CVCL_A5LW Copy
https://web.expasy.org/cellosaurus/CVCL_WW20
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_WW20 Copy
https://web.expasy.org/cellosaurus/CVCL_A5LX
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Proper citation: RRID:CVCL_A5LX Copy
https://web.expasy.org/cellosaurus/CVCL_4663
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RCB Cat# RCB2348, RRID:CVCL_4663 Copy
https://web.expasy.org/cellosaurus/CVCL_3351
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Established from a xenograft established in a nude mice., Population: Japanese.
Proper citation: RCB Cat# RCB1033, RRID:CVCL_3351 Copy
https://web.expasy.org/cellosaurus/CVCL_1610
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Established from a xenograft established in a nude mice., Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1610 Copy
https://web.expasy.org/cellosaurus/CVCL_4663
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_4663 Copy
https://web.expasy.org/cellosaurus/CVCL_1610
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Established from a xenograft established in a nude mice., Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RCB Cat# RCB1032, RRID:CVCL_1610 Copy
https://web.expasy.org/cellosaurus/CVCL_3351
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: Established from a xenograft established in a nude mice., Population: Japanese.
Proper citation: RRID:CVCL_3351 Copy
https://web.expasy.org/cellosaurus/CVCL_T745
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese.
Proper citation: RRID:CVCL_T745 Copy
https://web.expasy.org/cellosaurus/CVCL_1613
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_1613 Copy
https://web.expasy.org/cellosaurus/CVCL_LA02
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA02 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ83
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ83 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ72
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ72 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ99
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ99 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ86
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ86 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ71
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ71 Copy
https://web.expasy.org/cellosaurus/CVCL_LA04
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA04 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ75
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ75 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ81
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin parental cell lines express a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA). They can be used to introduce a GPCR tagged with another beta-galactosidase fragment (ProLink=PK)., Population: Caucasian.
Proper citation: RRID:CVCL_KZ81 Copy
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Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
