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URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151356946
Proper Citation: RRID:RRRC_00953
Description: Rattus norvegicus with name LE-ROSA26em1(EEF1A1-TetR, Fos-iCre)/BhopeRrrc from RGD.
Species: Rattus norvegicus
Notes: Two DNA expression constructs, the bacterial tetracyclin repressor (TetR) under the expression control of human EEF1A1 promoter and the improved Cre recombinase (iCre) under Fos promoter were joined in an antiparallel orientation in one rat ROSA26 targeting cassette. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. The DNA construct, together with CRISPR /Cas9 system, was injected to one cell Long-Evans (Crl:LE) rat embryos and founders were identified and bred for 8 generations at at NIDA IRP (Hope lab). Rat Resource and Research Center
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Source: Integrated Animals
Source Database: Rat Resource and Research Center (RRRC)
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
