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URL: http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695030
Proper Citation: RRID:RRRC_00846
Description: Rattus norvegicus with name SD.DA-Pex1tm(G843D-FRT-CAG-Pac-FRT)1Qly from RGD.
Species: Rattus norvegicus
Notes: This strain was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 5.8kb 5' and 1.7kb 3' homology arms. A G843D point mutation is introduced into the Pex1 gene. The 12th and 13th exons are flanked with two loxP sites. A FRT-CAG-Pac-FRT cassette is inserted into the intron between Pex1 13th and 14th exon. This strain mimics the Peroxisomal Disorders. Heterozygote does not show any abnormalities. Rat Resource and Research Center
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Source: Integrated Animals
Source Database: Rat Resource and Research Center (RRRC)