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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13451538
Proper Citation: RRID:RGD_13451538
Description: Rattus norvegicus with name FHH-Chr 1BN-Dusp5em1Mcwi from RGD.
Species: Rattus norvegicus
Notes: This strain was produced by injecting ZFNs targeting the following sequence CAGGGCAGCCGC-CACtggcaGAAGCTGCGGGAGGA in exon 1 of the rat Dusp5 gene into FHH-Chr 1BN/Mcwi embryos. The resulting mutation is a 14 bp deletion and a 3 bp insertion between nucleotides 449 and 464 in Dusp5 mRNA that creates a frame shift mutation which is predicted to introduce a premature stop codon at amino acid 121.
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No rating or validation information has been found for FHH-Chr 1BN-Dusp5em1Mcwi.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)