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Proper Citation: RRID:MGI:5771573
Description: Allele Detail: Gene trapped This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Gene trapped This is a legacy resource.
Phenotype: increased cellular sensitivity to DNA damaging agents, increased tumor incidence, increased lymphoma incidence, chromosomal instability, abnormal DNA replication, testicular atrophy, small testis, ovary cysts, increased Harderian gland adenoma incidence, abnormal seminiferous tubule epithelium morphology, increased adenocarcinoma incidence, decreased litter size, decreased cell proliferation, abnormal spermatogonia morphology, abnormal seminiferous tubule morphology, abnormal double-strand DNA break repair, abnormal X-Y chromosome synapsis during male meiosis, decreased primordial germ cell proliferation, increased primordial germ cell apoptosis, abnormal chiasmata formation, decreased primordial germ cell number, decreased testis weight, oligozoospermia, small testis, abnormal spermatogonia proliferation, abnormal cell physiology, abnormal chromosome morphology, abnormal double-strand DNA break repair, decreased testis weight, reduced fertility, early cellular replicative senescence, increased pituitary adenoma incidence, increased adenoma incidence, abnormal cell physiology, induced chromosome breakage, hepatic steatosis, abnormal ovary development, endometrium hyperplasia, testis hypoplasia, abnormal primary ovarian follicle morphology, Sertoli cell hyperplasia
Affected Gene: Brip1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
