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Proper Citation: RRID:MGI:3843242
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal aorta tunica media morphology, decreased creatinine clearance, cardiac fibrosis, adrenal medulla hyperplasia, abnormal physiological response to xenobiotic, abnormal heart morphology, abnormal bradykinin level, abnormal adrenal gland secretion, vascular smooth muscle hyperplasia, renal fibrosis, heart left ventricle hypertrophy, increased renin activity, increased mean systemic arterial blood pressure, increased heart rate, increased circulating renin level, increased circulating noradrenaline level, increased circulating antidiuretic hormone level, increased circulating aldosterone level, increased circulating adrenaline level, hypertension, hydrocephaly, enlarged myocardial fiber, enlarged adrenal medulla, decreased urine sodium level, oliguria, abnormal class switch recombination, decreased B cell number, decreased spleen germinal center number, decreased IgM level, decreased IgG3 level, decreased IgG2b level, decreased B cell proliferation, decreased IgG1 level
Affected Gene: Vav2
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
