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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38599146
Proper Citation: RRID:RGD_38599146
Description: Rattus norvegicus with name BN-Aireem1Ang-/- from RGD.
Species: Rattus norvegicus
Notes: The homozygous Aire mutant rats are littermates of cross of heterozygotes Aire mutant rats . The mutations created by ZFN reagents targeting to a DNA sequence 59-TGCCACCCAGACCCCCCACAAAGAGAAGAGCCCTGGAAGAG- 39 in exon 3 of the Aire gene. This mutant carries a 17-bp deletion in the nuclear localization signal sequence, causing a premature stop codon.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)