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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11531094
Proper Citation: RRID:RGD_11531094
Description: Rattus norvegicus with name SD-F8em1Sage/Novo from RGD.
Species: Rattus norvegicus
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat F8 into Sprague Dawley embryos. A premature translation stop in rat F8 was created in the mutant founders carrying a 13-bp deletion in exon 16. These mutant founders were backcrossed with Sprague Dawley to produce heterozygous offspring, which were then intercrossed to produce homozygous and heterozygous offspring.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)