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Proper Citation: RRID:MGI:3698734
Description: Allele Detail: Spontaneous This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Spontaneous This is a legacy resource.
Phenotype: decreased T cell proliferation, decreased T cell proliferation, decreased CD4-positive, alpha beta T cell number, osteoporosis, abnormal T cell selection, decreased CD8-positive, alpha-beta T cell number, abnormal T cell differentiation, abnormal thymus cell ratio, decreased CD8-positive, alpha-beta T cell number, abnormal positive T cell selection, abnormal splenic cell ratio, increased B cell number, abnormal thymocyte activation, increased immunoglobulin level, increased autoantibody level, decreased CD4-positive, alpha beta T cell number, joint swelling, decreased interleukin-2 secretion, fused joints, rheumatoid arthritis, abnormal positive T cell selection, chronic joint inflammation, abnormal lymph node cell ratio, increased susceptibility to induced arthritis, lung inflammation, increased activated T cell number, increased memory T cell number, decreased regulatory T cell number, increased interleukin-17 secretion, abnormal T cell clonal deletion, mixed cellular infiltration to dermis, joint dislocation
Affected Gene: Zap70
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
