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Proper Citation: RRID:MGI:3584247
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased susceptibility to endotoxin shock, abnormal innate immunity, enlarged Peyer's patches, increased tumor necrosis factor secretion, decreased trabecular bone volume, decreased body size, decreased compact bone thickness, decreased diameter of femur, abnormal osteoclast physiology, increased osteoblast cell number, abnormal compact bone morphology, abnormal trabecular bone morphology, increased interleukin-12b secretion, increased interleukin-6 secretion, increased neutrophil cell number, abnormal inflammatory response, kyphosis, increased osteoclast cell number, abnormal Peyer's patch morphology, abnormal immune system morphology
Affected Gene: Irak3
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
