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Proper Citation: RRID:MGI:3579861
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal metencephalon morphology, small thalamus, abnormal oculomotor nerve morphology, abnormal brain development, abnormal forebrain morphology, enlarged cerebellum, abnormal pretectal region morphology, small hippocampus, basisphenoid bone foramen, abnormal posterior commissure morphology, abnormal cartilage morphology, enlarged cerebellum, increased pons size, small thalamus, abnormal telencephalon morphology, abnormal midbrain-hindbrain boundary morphology, decreased midbrain size, abnormal rhombic lip morphology, abnormal cerebral aqueduct morphology, abnormal cerebral cortex morphology, abnormal diencephalon morphology, abnormal midbrain morphology, small hippocampus, abnormal hypothalamus morphology, abnormal inferior colliculus morphology, abnormal trigeminal V mesencephalic nucleus morphology, abnormal midbrain morphology, abnormal nervous system morphology, abnormal optic nerve morphology, abnormal cranium morphology, abnormal sphenoid bone morphology, abnormal mammillary body morphology, abnormal orbitosphenoid bone morphology, presphenoid bone hypoplasia, abnormal red nucleus morphology, abnormal oculomotor nucleus morphology, decreased substantia nigra size, abnormal superior colliculus morphology, abnormal tegmentum morphology, abnormal telencephalon morphology, abnormal trochlear nerve morphology, prenatal lethality, complete penetrance, small olfactory bulb, abnormal cerebral hemisphere morphology
Affected Gene: Otx1, Otx2
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No rating or validation information has been found for Otx1tm1Sia/Otx1+; Otx2tm1Sia/Otx2+.
No alerts have been found for Otx1tm1Sia/Otx1+; Otx2tm1Sia/Otx2+.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
