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Proper Citation: RRID:MGI:3036449
Description: Allele Detail: Targeted, Transgenic This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted, Transgenic This is a legacy resource.
Phenotype: cyanosis, abnormal pulmonary alveolus epithelial cell morphology, postnatal lethality, incomplete penetrance, increased respiratory mucosa goblet cell number, respiratory distress, postnatal lethality, incomplete penetrance, neonatal lethality, incomplete penetrance, pulmonary hyaline membrane formation, abnormal surfactant secretion, dilated respiratory conducting tubes, pulmonary vascular congestion, abnormal pulmonary alveolus wall morphology, increased neutrophil cell number, decreased surfactant secretion, absent alveolar lamellar bodies, abnormal lung saccule morphology, increased macrophage cell number, impaired lung alveolus development, absent type I pneumocytes, abnormal surfactant composition, impaired lung alveolus development, abnormal type II pneumocyte morphology, atelectasis, pup cannibalization
Affected Gene: Foxa2
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No rating or validation information has been found for Tg(SFTPC-rtTA)5Jaw; Tg(tetO-cre)1Jaw; Foxa2tm1Khk/Foxa2tm1Khk.
No alerts have been found for Tg(SFTPC-rtTA)5Jaw; Tg(tetO-cre)1Jaw; Foxa2tm1Khk/Foxa2tm1Khk.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
