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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: CD5 antigen|glucose homeostasis QTL 2|MX dynamin-like GTPase 1|NLR family; pyrin domain containing 12|cadherin related 23 (otocadherin)|forebrain weight 1|purinergic receptor P2X; ligand-gated ion channel; 7|latent transforming growth factor beta binding protein 4|arylalkylamine N-acetyltransferase|glucose homeostasis QTL 1|nuclear encoded tRNA arginine 5 (anticodon TCT)|microwave induced increase in complement receptor B cells|hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|annexin A6|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|aryl-hydrocarbon receptor|glucose homeostasis QTL 3|forebrain weight 2|beta-2 microglobulin|gamma-aminobutyric acid type A receptor subunit alpha 2|cytochrome c oxidase subunit 7A2 like; inbred strain: Cd5|Gluchos2|Mx1|Nlrp12|Cdh23|Fbrwt1|P2rx7|Ltbp4|Aanat|Gluchos1|n-TRtct5|Micrl|Hbb|Nnt|Anxa6|Apobec3|Ahr|Gluchos3|Fbrwt2|B2m|Gabra2|Cox7a2l
Affected Gene: CD5 antigen|glucose homeostasis QTL 2|MX dynamin-like GTPase 1|NLR family; pyrin domain containing 12|cadherin related 23 (otocadherin)|forebrain weight 1|purinergic receptor P2X; ligand-gated ion channel; 7|latent transforming growth factor beta binding protein 4|arylalkylamine N-acetyltransferase|glucose homeostasis QTL 1|nuclear encoded tRNA arginine 5 (anticodon TCT)|microwave induced increase in complement receptor B cells|hemoglobin beta chain complex|nicotinamide nucleotide transhydrogenase|annexin A6|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|aryl-hydrocarbon receptor|glucose homeostasis QTL 3|forebrain weight 2|beta-2 microglobulin|gamma-aminobutyric acid type A receptor subunit alpha 2|cytochrome c oxidase subunit 7A2 like
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services
Data set from Kravitz, Owen and Kretizer's 2012 paper "Optogenetic identification of striatal projection neuron subtypes during in vivo recordings."
